Protein: RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog (U1 70K) (U1 snRNP 70 kDa homolog) (U1-70K) (U1 small nuclear ribonucleoprotein SNP1) (U1 snRNP protein SNP1)

Gene: RU17, SNP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 104
UniProt ID: Q00916

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

696657

RU1A
U1 small nuclear ribonucleoprotein A

7

1

Small-scale

0.965

High

960460

NAM8
Protein NAM8

6

17

Small-scale

0.940

High

962592

RU1C
U1 small nuclear ribonucleoprotein C

5

1

High-throughput

0.922

High

962600

NCBP2
Nuclear cap-binding protein subunit 2

5

20

Small-scale

0.922

High

766941

RSMB
Small nuclear ribonucleoprotein-associated protein B

5

9

Small-scale

0.915

High

962589

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

6

0

Small-scale

0.895

High

710198

NCBP1
Nuclear cap-binding protein complex subunit 1

4

6

High-throughput

0.892

High

770323

RUXG
Small nuclear ribonucleoprotein G

4

11

High-throughput

0.881

High

962579

NOP3
Serine/arginine

4

20

Small-scale

0.878

High

962594

SMD2
Small nuclear ribonucleoprotein Sm D2

3

4

High-throughput

0.839

High

962581

SMD1
Small nuclear ribonucleoprotein Sm D1

3

2

Small-scale

0.827

High

873653

RUXF
Small nuclear ribonucleoprotein F

2

6

High-throughput

0.776

High

795407

SMD3
Small nuclear ribonucleoprotein Sm D3

2

14

High-throughput

0.754

High

962577

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

2

18

Small-scale

0.754

High

962601

RU2A
U2 small nuclear ribonucleoprotein A'

2

11

Small-scale

0.754

High

703256

PRP40
Pre-mRNA-processing protein PRP40

7

9

Small-scale

0.745

High

763244

PRP39
Pre-mRNA-processing factor 39

6

5

Small-scale

0.730

High

860150

SNU71
U1 small nuclear ribonucleoprotein component SNU71

8

0

Small-scale

0.716

High

962597

LUC7
Protein LUC7

5

7

High-throughput

0.714

High

962588

PRP42
U1 small nuclear ribonucleoprotein component PRP42

4

7

High-throughput

0.694

High

376897

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

18

High-throughput

0.691

High

676287

XPO1
Exportin-1

1

12

High-throughput

0.691

High

704702

PRP8
Pre-mRNA-splicing factor 8

3

4

Small-scale

0.680

High

962604

RUXE
Small nuclear ribonucleoprotein E

1

3

High-throughput

0.665

High

688798

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

7

High-throughput

0.656

High

732381

MUD2
Splicing factor MUD2

3

1

Small-scale

0.640

High

697244

BRR2
Pre-mRNA-splicing helicase BRR2

2

17

Small-scale

0.640

High

765034

IF4F1
Eukaryotic initiation factor 4F subunit p150

2

17

High-throughput

0.621

High

962598

WHI4
Protein WHI4

1

12

Small-scale

0.621

High

743639

HMT1
Protein arginine N-methyltransferase 1

2

18

Small-scale

0.619

High

694189

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

19

High-throughput

0.618

High

962582

CUS1
Cold sensitive U2 snRNA suppressor 1

1

2

High-throughput

0.618

High

962603

BBP
Branchpoint-bridging protein

1

20

Small-scale

0.618

High

605680

KIN3
Serine/threonine-protein kinase KIN3

1

17

High-throughput

0.590

High

425645

KAPR
cAMP-dependent protein kinase regulatory subunit

1

4

High-throughput

0.536

High

512367

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.536

High

594355

PP11
Serine/threonine-protein phosphatase PP1-1

1

9

High-throughput

0.536

High

733227

SA190
SIT4-associating protein SAP190

1

1

High-throughput

0.536

High

748679

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.536

High

774944

MAM33
Mitochondrial acidic protein MAM33

1

2

High-throughput

0.536

High

777316

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.536

High

962583

IMA1
Importin subunit alpha

1

1

High-throughput

0.536

High

452122

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

1

High-throughput

0.508

High

520675

REV1
DNA repair protein REV1

1

3

High-throughput

0.508

High

542143

CYC8
General transcriptional corepressor CYC8

1

9

High-throughput

0.508

High

643197

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

10

High-throughput

0.508

High

660054

KIP1
Kinesin-like protein KIP1

1

1

High-throughput

0.508

High

675769

RENT1
ATP-dependent helicase NAM7

1

14

Small-scale

0.508

High

857270

ACS2
Acetyl-coenzyme A synthetase 2

1

1

High-throughput

0.508

High

746531

IMB2
Importin subunit beta-2

1

7

Small-scale

0.501

High

633488

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.500

High

424122

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

3

High-throughput

0.489

High

424230

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

3

High-throughput

0.489

High

737199

LONM
Lon protease homolog, mitochondrial

1

6

High-throughput

0.489

High

962585

HAS1
ATP-dependent RNA helicase HAS1

1

16

High-throughput

0.489

High

599378

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.486

High

609128

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.486

High

698564

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.486

High

792335

YCH1
CDC25-like phosphatase YCH1

1

0

High-throughput

0.486

High

962580

GCR2
Glycolytic genes transcriptional activator GCR2

1

0

High-throughput

0.486

High

962586

MTND
Acireductone dioxygenase

1

0

High-throughput

0.486

High

962587

USA1
U1 SNP1-associating protein 1

1

0

Small-scale

0.486

High

962590

IOC4
ISWI one complex protein 4

1

0

High-throughput

0.486

High

962599

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.486

High

962602

PALA
pH-response regulator protein palA/RIM20

1

0

High-throughput

0.486

High

693347

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.479

High

624154

DBP2
ATP-dependent RNA helicase DBP2

1

10

High-throughput

0.479

High

663047

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

731757

SN114
Pre-mRNA-splicing factor SNU114

1

10

Small-scale

0.479

High

775231

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.479

High

962593

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

962605

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

1

Small-scale

0.479

High

446211

MYO1
Myosin-1

1

3

High-throughput

0.464

High

715841

MDJ1
DnaJ homolog 1, mitochondrial

1

5

High-throughput

0.464

High

735233

RM04
Large ribosomal subunit protein uL29m

1

1

High-throughput

0.464

High

698111

YSC84
Protein YSC84

1

9

High-throughput

0.457

High

764115

RV167
Reduced viability upon starvation protein 167

1

4

High-throughput

0.457

High

797838

LSB3
LAS seventeen-binding protein 3

1

4

High-throughput

0.457

High

521036

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

556236

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.457

High

494717

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

692339

PRP19
Pre-mRNA-processing factor 19

1

16

Small-scale

0.445

High

695311

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

754631

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

769193

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

520548

RM02
Large ribosomal subunit protein bL27m

1

2

High-throughput

0.437

High

613741

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.437

High

962584

NOG1
Nucleolar GTP-binding protein 1

1

7

High-throughput

0.437

High

478438

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.407

High

962595

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

4

High-throughput

0.407

High

747225

EXO84
Exocyst complex component EXO84

1

0

Small-scale

0.305

High

754100

DOG1
2-deoxyglucose-6-phosphate phosphatase 1

1

0

High-throughput

0.279

Low

757321

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.279

Low

778763

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.279

Low

962596

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.279

Low

140795

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.265

Low

635033

YCZ1
Uncharacterized protein YCR101C

1

0

High-throughput

0.265

Low

763701

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.265

Low

767593

NU157
Nucleoporin NUP157

1

0

High-throughput

0.265

Low

797994

OSW7
Outer spore wall protein 7

1

0

High-throughput

0.265

Low

962578

ACAC
Acetyl-CoA carboxylase

1

0

High-throughput

0.265

Low

962591

CRR1
Probable glycosidase CRR1

1

0

High-throughput

0.265

Low

434712

CHS1
Chitin synthase 1

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024