Protein: TOF2
Topoisomerase 1-associated factor 2

Gene: TOF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: Q02208

Gene Ontology (top 5):
GO:0000182 - rDNA binding
GO:0000183 - rDNA heterochromatin formation
GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0007000 - nucleolus organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

961464

CDC14
Tyrosine-protein phosphatase CDC14

6

1

Small-scale

0.738

High

636074

CSM1
Monopolin complex subunit CSM1

8

0

Small-scale

0.718

High

810717

NET1
Nucleolar protein NET1

4

2

Small-scale

0.693

High

416244

SIR2
NAD-dependent histone deacetylase SIR2

3

1

Small-scale

0.667

High

140796

FOB1
DNA replication fork-blocking protein FOB1

3

1

Small-scale

0.660

High

969461

LRS4
Monopolin complex subunit LRS4

2

1

Small-scale

0.584

High

550104

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.536

High

584785

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

388120

TOP1
DNA topoisomerase 1

1

0

Small-scale

0.529

High

772318

ATAD2
ATPase histone chaperone YTA7

2

1

High-throughput

0.521

High

841419

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.512

High

512397

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.489

High

624747

CG23
G2/mitotic-specific cyclin-3

1

2

High-throughput

0.489

High

744979

CHK1
Serine/threonine-protein kinase CHK1

1

1

High-throughput

0.489

High

969460

VHS1
Serine/threonine-protein kinase VHS1

1

2

High-throughput

0.489

High

501403

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

1

High-throughput

0.479

High

648419

NSR1
Nuclear localization sequence-binding protein

1

1

High-throughput

0.479

High

693874

SRP40
Suppressor protein SRP40

1

1

High-throughput

0.479

High

716328

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

810445

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

862512

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

1

High-throughput

0.479

High

963165

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

969462

RTN1
Reticulon-like protein 1

1

0

Small-scale

0.458

High

969457

TOF2
Topoisomerase 1-associated factor 2

1

2

High-throughput

0.457

High

494742

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

544269

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.445

High

969464

RIO1
Serine/threonine-protein kinase RIO1

1

1

Small-scale

0.439

High

356668

H4
Histone H4

1

1

Small-scale

0.437

High

429757

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.437

High

604603

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

2

High-throughput

0.437

High

606111

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.437

High

655648

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.437

High

663073

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

692704

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

1

High-throughput

0.437

High

693148

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

1

High-throughput

0.437

High

805018

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

1

High-throughput

0.437

High

812081

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

355596

H2B1
Histone H2B.1

1

1

High-throughput

0.407

High

492166

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.407

High

633499

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.407

High

689938

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.407

High

691926

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

1

High-throughput

0.407

High

695332

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.407

High

733290

SET3
SET domain-containing protein 3

1

2

High-throughput

0.407

High

769226

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

859061

HOS2
Probable histone deacetylase HOS2

1

1

High-throughput

0.407

High

969458

LGE1
Transcriptional regulatory protein LGE1

1

1

High-throughput

0.407

High

969465

RLF2
Chromatin assembly factor 1 subunit p90

1

1

High-throughput

0.407

High

964864

CTF4
DNA polymerase alpha-binding protein

1

0

Small-scale

0.309

High

859571

MLC1
Myosin light chain 1

1

0

High-throughput

0.269

Low

969459

SLD5
DNA replication complex GINS protein SLD5

1

0

Small-scale

0.249

Low

969463

CDC45
Cell division control protein 45

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024