Protein: THDH
Threonine dehydratase, mitochondrial (EC 4.3.1.19) (Threonine deaminase)

Gene: THDH, ILV1
Organism: Saccharomyces cerevisiae S288C
Interactions: 113
UniProt ID: P00927

Gene Ontology (top 5):
GO:0003941 - L-serine ammonia-lyase activity
GO:0004794 - threonine deaminase activity
GO:0005739 - mitochondrion
GO:0006565 - L-serine catabolic process
GO:0006567 - threonine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343054

THDH
Threonine dehydratase, mitochondrial

2

19

High-throughput

0.775

High

343084

HSP60
Heat shock protein 60, mitochondrial

4

2

High-throughput

0.687

High

343082

HSC82
ATP-dependent molecular chaperone HSC82

3

11

High-throughput

0.643

High

343088

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

20

High-throughput

0.618

High

343076

HSP71
Heat shock protein SSA1

4

8

High-throughput

0.608

High

343112

EF1G2
Elongation factor 1-gamma 2

2

0

High-throughput

0.595

High

343066

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

2

1

High-throughput

0.571

High

343126

LYS12
Homoisocitrate dehydrogenase, mitochondrial

2

3

High-throughput

0.571

High

343159

RUVB2
RuvB-like protein 2

2

7

High-throughput

0.558

High

343057

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.536

High

343139

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

343100

HS104
Heat shock protein 104

2

7

Small-scale

0.533

High

334390

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.515

High

334851

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.515

High

343113

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.513

High

343104

EI2BB
Translation initiation factor eIF2B subunit beta

1

2

High-throughput

0.508

High

343063

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.493

High

343058

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

3

High-throughput

0.489

High

343067

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.489

High

343127

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.489

High

343070

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.479

High

343074

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

343083

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

343095

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

1

High-throughput

0.479

High

343097

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

3

High-throughput

0.479

High

343110

HSP78
Heat shock protein 78, mitochondrial

1

7

High-throughput

0.479

High

343122

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

343125

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

3

High-throughput

0.479

High

343133

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

343136

ALAM
Probable alanine aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

343141

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.479

High

343144

ESP1
Separin

1

1

High-throughput

0.479

High

343092

CSM1
Monopolin complex subunit CSM1

1

1

High-throughput

0.464

High

343102

IMB3
Importin subunit beta-3

1

2

High-throughput

0.464

High

343161

MTR10
mRNA transport regulator MTR10

1

1

High-throughput

0.464

High

343101

OAC1
Mitochondrial oxaloacetate transport protein

1

0

High-throughput

0.458

High

343107

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

343114

YKT6
Synaptobrevin homolog YKT6

1

0

High-throughput

0.458

High

343145

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

343150

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

343065

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

343077

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

343081

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.445

High

343135

RL4P
Large ribosomal subunit protein uL4m

1

1

High-throughput

0.445

High

343078

MTF2
Mitochondrial transcription factor 2

1

0

High-throughput

0.438

High

141015

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.437

High

343055

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

343056

HSP82
ATP-dependent molecular chaperone HSP82

1

11

High-throughput

0.437

High

343059

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

343060

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

343061

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.437

High

343062

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

343068

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

343069

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

343075

IF4A
ATP-dependent RNA helicase eIF4A

1

2

High-throughput

0.437

High

343080

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

343085

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.437

High

343086

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.437

High

343087

SIS1
Protein SIS1

1

4

High-throughput

0.437

High

343089

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.437

High

343094

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

343098

URA7
CTP synthase 1

1

1

High-throughput

0.437

High

343099

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

343108

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

343109

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

343111

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

343118

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.437

High

343124

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

343132

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

343134

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.437

High

343137

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.437

High

343142

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

343146

RUVB1
RuvB-like protein 1

1

7

High-throughput

0.437

High

343148

SIZ1
E3 SUMO-protein ligase SIZ1

1

3

High-throughput

0.437

High

343152

TFC6
Transcription factor tau 91 kDa subunit

1

2

High-throughput

0.437

High

343153

SUB2
ATP-dependent RNA helicase SUB2

1

1

High-throughput

0.437

High

343155

MCA1
Metacaspase-1

1

1

High-throughput

0.437

High

343156

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

343096

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.426

High

343160

GLT1
Glutamate synthase [NADH]

1

0

High-throughput

0.426

High

339304

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.407

High

343079

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.407

High

343091

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.407

High

343105

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.407

High

343120

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.407

High

343123

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.407

High

343129

PFD1
Prefoldin subunit 1

1

2

High-throughput

0.407

High

343090

RAD51
DNA repair protein RAD51

2

0

High-throughput

0.324

High

343143

MUK1
Protein MUK1

2

0

High-throughput

0.307

High

343116

TOS1
Probable circularly permuted 1,3-beta-glucanase TOS1

2

0

High-throughput

0.307

High

343130

BBC1
Myosin tail region-interacting protein MTI1

1

0

High-throughput

0.282

High

343140

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.282

High

343119

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.279

Low

343128

SA155
SIT4-associating protein SAP155

1

0

High-throughput

0.279

Low

343064

CDC31
Cell division control protein 31

1

0

High-throughput

0.269

Low

343117

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.265

Low

343151

BCP1
Protein BCP1

1

0

High-throughput

0.265

Low

343157

NBP2
NAP1-binding protein 2

1

0

High-throughput

0.251

Low

343071

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

343072

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

343073

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.249

Low

343093

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

343103

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

343115

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.249

Low

343121

SBE22
Protein SBE22

1

0

High-throughput

0.249

Low

343131

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.249

Low

343138

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.249

Low

343158

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.249

Low

343106

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

0

High-throughput

0.238

Low

343149

MYO5
Myosin-5

1

0

High-throughput

0.238

Low

343154

ADY3
Accumulates dyads protein 3

1

0

High-throughput

0.238

Low

343147

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024