Protein: SYTC
Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)

Gene: SYTC, THS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 111
UniProt ID: P04801

Gene Ontology (top 5):
GO:0004829 - threonine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006435 - threonyl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

388920

SYTC
Threonine--tRNA ligase, cytoplasmic

2

12

High-throughput

0.776

High

388953

HS104
Heat shock protein 104

3

4

Small-scale

0.640

High

388990

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

4

High-throughput

0.640

High

388926

SYH
Histidine--tRNA ligase, mitochondrial

1

1

High-throughput

0.618

High

388972

SYG
Glycine--tRNA ligase 1, mitochondrial

1

9

High-throughput

0.618

High

388977

YHI0
Putative proline--tRNA ligase YHR020W

1

12

High-throughput

0.618

High

388935

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.611

High

388945

SIS1
Protein SIS1

3

5

High-throughput

0.587

High

365516

HSP82
ATP-dependent molecular chaperone HSP82

2

9

Small-scale

0.584

High

388938

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.571

High

389023

RRP6
Exosome complex exonuclease RRP6

2

4

High-throughput

0.558

High

388985

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.552

High

388941

FKBP
FK506-binding protein 1

1

2

High-throughput

0.536

High

388965

PTK1
Serine/threonine-protein kinase PTK1/STK1

1

6

High-throughput

0.536

High

389002

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

389005

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

388968

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.513

High

389008

YMY9
Glucose-6-phosphate 1-epimerase

1

0

High-throughput

0.513

High

388962

HSL1
Probable serine/threonine-protein kinase HSL1

1

5

High-throughput

0.501

High

388975

KSP1
Serine/threonine-protein kinase KSP1

1

3

High-throughput

0.501

High

388993

GYP7
GTPase-activating protein GYP7

1

0

High-throughput

0.493

High

389012

SEN15
tRNA-splicing endonuclease subunit SEN15

1

1

High-throughput

0.489

High

389016

PIN3
[PSI+] inducibility protein 3

1

1

Small-scale

0.481

High

388974

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.480

High

141030

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

343779

SYMC
Methionine--tRNA ligase, cytoplasmic

1

10

High-throughput

0.479

High

388921

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

388923

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

388924

SC160
Protein SCP160

1

2

High-throughput

0.479

High

388927

SYV
Valine--tRNA ligase, mitochondrial

1

9

High-throughput

0.479

High

388928

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

9

Small-scale

0.479

High

388932

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

388936

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

388937

SYQ
Glutamine--tRNA ligase

1

6

High-throughput

0.479

High

388939

SYKC
Lysine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

388944

IF5A1
Eukaryotic translation initiation factor 5A-1

1

2

High-throughput

0.479

High

388947

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.479

High

388948

SYLC
Leucine--tRNA ligase, cytoplasmic

1

11

High-throughput

0.479

High

388952

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

388955

ZUO1
Zuotin

1

6

High-throughput

0.479

High

388957

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

388958

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

388960

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

388964

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

388966

KKQ8
Probable serine/threonine-protein kinase KKQ8

1

8

High-throughput

0.479

High

388967

EF1G2
Elongation factor 1-gamma 2

1

2

High-throughput

0.479

High

388969

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.479

High

388970

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

388971

RM16
Large ribosomal subunit protein uL16m

1

1

High-throughput

0.479

High

388976

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

388978

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.479

High

388979

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.479

High

388981

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

388987

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.479

High

388992

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

388994

HOSC
Homocitrate synthase, cytosolic isozyme

1

2

High-throughput

0.479

High

388995

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

388999

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.479

High

389000

SPC98
Spindle pole body component SPC98

1

1

High-throughput

0.479

High

389001

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

1

High-throughput

0.479

High

389003

PDR16
Phosphatidylinositol transfer protein PDR16

1

1

High-throughput

0.479

High

389004

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.479

High

389007

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

389009

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

389011

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

389017

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

388942

ATP5E
ATP synthase subunit epsilon, mitochondrial

1

0

High-throughput

0.458

High

388946

RBSK
Ribokinase

1

0

High-throughput

0.458

High

388988

TM108
Protein TMA108

1

0

High-throughput

0.458

High

388989

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

High-throughput

0.458

High

389018

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

389021

TIM18
Mitochondrial import inner membrane translocase subunit TIM18

1

0

High-throughput

0.458

High

388959

PRP40
Pre-mRNA-processing protein PRP40

1

1

High-throughput

0.457

High

389019

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.457

High

388930

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.445

High

388933

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

388934

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

388940

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.445

High

388956

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

388961

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

388984

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.445

High

388997

INO80
Chromatin-remodeling ATPase INO80

1

2

High-throughput

0.445

High

388922

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

388925

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

388929

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

388943

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.437

High

388951

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

388954

MET4
Transcriptional activator of sulfur metabolism MET4

1

1

High-throughput

0.437

High

388973

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

388980

RPN10
26S proteasome regulatory subunit RPN10

1

2

High-throughput

0.437

High

388983

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

388996

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

388998

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

389006

MAP1
Methionine aminopeptidase 1

1

1

High-throughput

0.437

High

389010

YMC0
Uncharacterized protein YML020W

1

1

High-throughput

0.437

High

389014

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

389015

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

389020

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

389022

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

388982

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

389013

YL287
Uncharacterized protein YLR287C

1

0

High-throughput

0.426

High

388949

LAC1
Ceramide synthase LAC1

1

1

High-throughput

0.407

High

388986

ELO3
Fatty acid elongase 3

1

1

High-throughput

0.407

High

388991

TRS85
Trafficking protein particle complex III-specific subunit 85

1

0

High-throughput

0.269

Low

388931

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.249

Low

388963

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

389024

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.249

Low

389025

RKM4
Ribosomal lysine N-methyltransferase 4

1

0

High-throughput

0.249

Low

389026

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.249

Low

388950

SEC20
Protein transport protein SEC20

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024