Protein: PHO4
Phosphate system positive regulatory protein PHO4

Gene: PHO4
Organism: Saccharomyces cerevisiae S288C
Interactions: 171
UniProt ID: P07270

Gene Ontology (top 5):
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006338 - chromatin remodeling
GO:0016036 - cellular response to phosphate starvation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

425258

PHO4
Phosphate system positive regulatory protein PHO4

5

0

Small-scale

0.855

High

425287

PHO85
Cyclin-dependent protein kinase PHO85

14

1

Small-scale

0.761

High

425292

PHO80
PHO85 cyclin PHO80

6

1

Small-scale

0.733

High

425220

PHO2
Regulatory protein PHO2

9

0

Small-scale

0.724

High

425363

MSN5
Protein MSN5

3

1

Small-scale

0.672

High

425320

IMB3
Importin subunit beta-3

3

0

Small-scale

0.650

High

425317

TF2B
Transcription initiation factor IIB

3

0

Small-scale

0.619

High

425280

TBP
TATA-box-binding protein

2

0

Small-scale

0.603

High

425298

SIN3
Transcriptional regulatory protein SIN3

2

0

Small-scale

0.592

High

425323

GSP1
GTP-binding nuclear protein GSP1/CNR1

2

0

Small-scale

0.569

High

425324

PRS7
26S proteasome regulatory subunit 7 homolog

1

2

Small-scale

0.561

High

425369

PRS10
26S proteasome subunit RPT4

1

2

Small-scale

0.561

High

425375

PRS8
26S proteasome regulatory subunit 8 homolog

1

1

Small-scale

0.561

High

141059

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.536

High

404449

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.536

High

425264

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.536

High

425274

YG22B
Transposon Ty2-GR2 Gag-Pol polyprotein

1

7

High-throughput

0.536

High

425301

STE11
Serine/threonine-protein kinase STE11

1

1

High-throughput

0.536

High

425303

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.536

High

425307

YC21B
Transposon Ty2-C Gag-Pol polyprotein

1

7

High-throughput

0.536

High

425314

NSR1
Nuclear localization sequence-binding protein

1

1

High-throughput

0.536

High

425318

XPO1
Exportin-1

1

1

High-throughput

0.536

High

425327

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.536

High

425341

HRB1
Serine/arginine

1

1

High-throughput

0.536

High

425357

HOSC
Homocitrate synthase, cytosolic isozyme

1

1

High-throughput

0.536

High

425362

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.536

High

425378

YD22B
Transposon Ty2-DR2 Gag-Pol polyprotein

1

7

High-throughput

0.536

High

425380

YM13B
Transposon Ty1-MR1 Gag-Pol polyprotein

1

7

High-throughput

0.536

High

425383

YM14B
Transposon Ty1-MR2 Gag-Pol polyprotein

1

7

High-throughput

0.536

High

425394

HOSM
Homocitrate synthase, mitochondrial

1

1

High-throughput

0.536

High

425397

RL7B
Large ribosomal subunit protein uL30B

1

1

High-throughput

0.536

High

425398

NOP56
Nucleolar protein 56

1

1

High-throughput

0.536

High

425399

YD21B
Transposon Ty2-DR1 Gag-Pol polyprotein

1

7

High-throughput

0.536

High

425402

RL11B
Large ribosomal subunit protein uL5B

1

1

High-throughput

0.536

High

425404

YN12B
Transposon Ty1-NL2 Gag-Pol polyprotein

1

7

High-throughput

0.536

High

425281

INO4
Protein INO4

1

0

Small-scale

0.529

High

425334

BOB1
Protein BOB1

1

0

High-throughput

0.518

High

360694

TBB
Tubulin beta chain

1

0

High-throughput

0.513

High

406179

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.513

High

419761

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.513

High

421540

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.513

High

423496

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.513

High

425259

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

High-throughput

0.513

High

425262

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

425277

AK
Aspartokinase

1

0

High-throughput

0.513

High

425294

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.513

High

425295

RCC1
Guanine nucleotide exchange factor SRM1

1

0

High-throughput

0.513

High

425296

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.513

High

425297

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.513

High

425305

STE50
Protein STE50

1

0

High-throughput

0.513

High

425306

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.513

High

425308

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

425310

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

425311

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

425315

URA7
CTP synthase 1

1

0

High-throughput

0.513

High

425316

AROC
Chorismate synthase ARO2

1

0

High-throughput

0.513

High

425322

AROG
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited

1

0

High-throughput

0.513

High

425330

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.513

High

425340

LSM12
Protein LSM12

1

0

High-throughput

0.513

High

425344

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.513

High

425346

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

High-throughput

0.513

High

425348

TM108
Protein TMA108

1

0

High-throughput

0.513

High

425353

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.513

High

425355

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.513

High

425358

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.513

High

425361

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.513

High

425377

DIG1
Down-regulator of invasive growth 1

1

0

High-throughput

0.513

High

425382

MYO5
Myosin-5

1

0

High-throughput

0.513

High

425388

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.513

High

425389

CDC73
Cell division control protein 73

1

0

High-throughput

0.513

High

425390

TSR1
Ribosome biogenesis protein TSR1

1

0

High-throughput

0.513

High

425393

CHS5
Chitin biosynthesis protein CHS5

1

0

High-throughput

0.513

High

425286

CSK21
Casein kinase II subunit alpha

1

2

Small-scale

0.501

High

425290

CSK22
Casein kinase II subunit alpha'

1

1

Small-scale

0.501

High

425309

PCL2
PHO85 cyclin-2

1

1

Small-scale

0.501

High

425373

H3
Histone H3

1

0

High-throughput

0.493

High

145672

RL36B
Large ribosomal subunit protein eL36B

1

1

High-throughput

0.489

High

357426

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.489

High

382676

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.489

High

399820

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.489

High

405331

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.489

High

406089

RL36A
Large ribosomal subunit protein eL36A

1

1

High-throughput

0.489

High

407442

RS9B
Small ribosomal subunit protein uS4B

1

1

High-throughput

0.489

High

425260

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.489

High

425261

RS19B
Small ribosomal subunit protein eS19B

1

1

High-throughput

0.489

High

425265

RS25B
Small ribosomal subunit protein eS25B

1

1

High-throughput

0.489

High

425293

DBP3
ATP-dependent RNA helicase DBP3

1

1

High-throughput

0.489

High

425302

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.489

High

425313

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.489

High

425337

RS27B
Small ribosomal subunit protein eS27B

1

1

High-throughput

0.489

High

425349

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.489

High

425350

RS29A
Small ribosomal subunit protein uS14A

1

1

High-throughput

0.489

High

425351

RS29B
Small ribosomal subunit protein uS14B

1

1

High-throughput

0.489

High

425356

RS7B
Small ribosomal subunit protein eS7B

1

1

High-throughput

0.489

High

425367

RL26B
Large ribosomal subunit protein uL24B

1

1

High-throughput

0.489

High

425374

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.489

High

425403

RS25A
Small ribosomal subunit protein eS25A

1

1

High-throughput

0.489

High

339344

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.481

High

412615

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

425279

SCH9
Serine/threonine-protein kinase SCH9

1

0

High-throughput

0.480

High

425283

CYC8
General transcriptional corepressor CYC8

1

0

Small-scale

0.480

High

425300

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

425329

T2EB
Transcription initiation factor IIE subunit beta

1

0

Small-scale

0.480

High

425335

HMT1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.480

High

425365

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.480

High

425396

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.480

High

425263

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.479

High

425266

RL11A
Large ribosomal subunit protein uL5A

1

1

High-throughput

0.479

High

425304

PCL1
PHO85 cyclin-1

1

1

Small-scale

0.479

High

425359

ASNS1
Asparagine synthetase [glutamine-hydrolyzing] 1

1

1

High-throughput

0.479

High

425391

YD23B
Transposon Ty2-DR3 Gag-Pol polyprotein

1

7

High-throughput

0.479

High

425288

PHO81
Phosphate system positive regulatory protein PHO81

1

0

Small-scale

0.460

High

376584

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.458

High

419434

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

424784

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.458

High

425267

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.458

High

425272

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.458

High

425282

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.458

High

425321

RME1
Zinc finger protein RME1

1

0

High-throughput

0.458

High

425326

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

425364

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.458

High

425370

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

425379

TAF8
Transcription initiation factor TFIID subunit 8

1

0

High-throughput

0.458

High

425387

NMA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

High-throughput

0.458

High

425395

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

193992

YA075
Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W

1

1

High-throughput

0.445

High

425360

ASNS2
Asparagine synthetase [glutamine-hydrolyzing] 2

1

1

High-throughput

0.445

High

425269

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.437

High

425271

RS23B
Small ribosomal subunit protein uS12B

1

1

High-throughput

0.437

High

425400

NOP58
Nucleolar protein 58

1

1

High-throughput

0.437

High

425276

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

425278

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

425299

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

425325

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

425339

PIH1
Protein interacting with Hsp90 1

1

0

High-throughput

0.426

High

425342

STM1
Suppressor protein STM1

1

0

High-throughput

0.426

High

425368

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.426

High

425268

RL43A
Large ribosomal subunit protein eL43A

1

1

High-throughput

0.407

High

425270

RS23A
Small ribosomal subunit protein uS12A

1

1

High-throughput

0.407

High

425376

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

0

Small-scale

0.292

High

425338

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

0

High-throughput

0.282

High

425284

SEC23
Protein transport protein SEC23

1

0

High-throughput

0.279

Low

425285

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.279

Low

425289

HXKG
Glucokinase-1

1

0

High-throughput

0.279

Low

425291

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.279

Low

425312

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.279

Low

425328

EAP1
Protein EAP1

1

0

High-throughput

0.279

Low

425331

APE3
Aminopeptidase Y

1

0

High-throughput

0.279

Low

425332

GLY1
Low specificity L-threonine aldolase

1

0

High-throughput

0.279

Low

425333

VRP1
Verprolin

1

0

High-throughput

0.279

Low

425336

GUAA
GMP synthase [glutamine-hydrolyzing]

1

0

High-throughput

0.279

Low

425343

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.279

Low

425347

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.279

Low

425352

KRI1
Protein KRI1

1

0

High-throughput

0.279

Low

425354

BBC1
Myosin tail region-interacting protein MTI1

1

0

High-throughput

0.279

Low

425366

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.279

Low

425371

EF3B
Elongation factor 3B

1

0

High-throughput

0.279

Low

425372

PUR91
Bifunctional purine biosynthesis protein ADE16 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.279

Low

425381

RRB1
Ribosome assembly protein RRB1

1

0

High-throughput

0.279

Low

425384

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.279

Low

425385

BCH1
Protein BCH1

1

0

High-throughput

0.279

Low

425401

GLT1
Glutamate synthase [NADH]

1

0

High-throughput

0.279

Low

336705

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.269

Low

399703

RLA1
Large ribosomal subunit protein P1A

1

0

High-throughput

0.249

Low

425273

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

425275

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.249

Low

425319

EF2
Elongation factor 2

1

0

High-throughput

0.249

Low

425386

PUR8
Adenylosuccinate lyase

1

0

Small-scale

0.249

Low

425392

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

425345

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024