Protein: ALF
Fructose-bisphosphate aldolase (FBP aldolase) (FBPA) (EC 4.1.2.13) (Fructose-1,6-bisphosphate aldolase)

Gene: ALF, FBA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 224
UniProt ID: P14540

Gene Ontology (top 5):
GO:0004332 - fructose-bisphosphate aldolase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006094 - gluconeogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

537359

SIS1
Protein SIS1

3

2

High-throughput

0.643

High

537337

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.618

High

537447

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

0

High-throughput

0.613

High

510111

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.611

High

375569

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

1

Small-scale

0.604

High

537477

GCN5
Histone acetyltransferase GCN5

2

0

High-throughput

0.602

High

334878

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

2

3

Small-scale

0.588

High

340598

PGK
Phosphoglycerate kinase

2

1

Small-scale

0.588

High

490195

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

493083

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.571

High

537341

HSC82
ATP-dependent molecular chaperone HSC82

2

2

High-throughput

0.571

High

537365

MAS5
Mitochondrial protein import protein MAS5

2

2

High-throughput

0.571

High

537464

RHO5
GTP-binding protein RHO5

2

0

Small-scale

0.569

High

537466

FAR11
Factor arrest protein 11

2

0

High-throughput

0.563

High

537431

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

537470

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

446099

MYO1
Myosin-1

1

0

Small-scale

0.529

High

537456

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.513

High

537462

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

537480

ACL4
Assembly chaperone of RPL4

1

0

High-throughput

0.513

High

537487

ASR1
Alcohol-sensitive RING finger protein 1

1

0

High-throughput

0.513

High

537346

GLRX2
Glutaredoxin-2

1

1

Small-scale

0.501

High

537362

GLRX1
Glutaredoxin-1

1

1

Small-scale

0.501

High

485626

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.500

High

537345

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.500

High

537491

RTC1
Restriction of telomere capping protein 1

1

1

High-throughput

0.500

High

537509

AP2M
AP-2 complex subunit mu

1

1

High-throughput

0.500

High

474252

NFT1
ABC transporter NFT1

1

1

High-throughput

0.494

High

537391

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

1

High-throughput

0.494

High

537444

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

1

High-throughput

0.494

High

412934

KAPB
cAMP-dependent protein kinase type 2

1

0

High-throughput

0.479

High

503041

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.479

High

537339

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.479

High

537351

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.479

High

537353

PP11
Serine/threonine-protein phosphatase PP1-1

1

0

High-throughput

0.479

High

537360

MSH3
DNA mismatch repair protein MSH3

1

0

High-throughput

0.479

High

537375

CDC3
Cell division control protein 3

1

0

High-throughput

0.479

High

537376

CDC12
Cell division control protein 12

1

0

High-throughput

0.479

High

537379

DUR1
Urea amidolyase [Includes: Urea carboxylase

1

0

High-throughput

0.479

High

537381

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.479

High

537382

FIMB
Fimbrin

1

0

High-throughput

0.479

High

537388

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.479

High

537402

IMB2
Importin subunit beta-2

1

0

High-throughput

0.479

High

537419

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.479

High

537422

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.479

High

537449

SA155
SIT4-associating protein SAP155

1

0

High-throughput

0.479

High

537459

RPN14
26S proteasome regulatory subunit RPN14

1

0

High-throughput

0.479

High

537474

IMA1
Importin subunit alpha

1

0

High-throughput

0.479

High

537488

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.479

High

537504

ATG5
Autophagy protein 5

1

0

High-throughput

0.479

High

334421

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

3

High-throughput

0.479

High

334598

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

3

High-throughput

0.479

High

339402

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

339990

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.479

High

342636

ENO1
Enolase 1

1

1

High-throughput

0.479

High

342837

ENO2
Enolase 2

1

1

High-throughput

0.479

High

343514

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

365697

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

389208

HXKA
Hexokinase-1

1

1

High-throughput

0.479

High

389360

HXKB
Hexokinase-2

1

1

High-throughput

0.479

High

477846

HSP77
Import motor subunit, mitochondrial

1

3

High-throughput

0.479

High

498418

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.479

High

537350

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.479

High

537463

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.479

High

141122

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

336656

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

341701

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.458

High

343343

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

382917

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

399311

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.458

High

404292

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.458

High

405393

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

406735

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

410881

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

413268

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

421742

KAD2
Adenylate kinase

1

0

High-throughput

0.458

High

424981

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.458

High

425578

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.458

High

425724

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

450267

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

470822

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

471986

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

479887

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

480445

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

482044

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

520894

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

522659

UNG
Uracil-DNA glycosylase

1

0

High-throughput

0.458

High

524127

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

537338

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

537340

TAL1
Transaldolase

1

0

High-throughput

0.458

High

537343

THRC
Threonine synthase

1

0

High-throughput

0.458

High

537348

PGTB1
Geranylgeranyl transferase type-1 subunit beta

1

0

High-throughput

0.458

High

537349

IRA2
Inhibitory regulator protein IRA2

1

0

Small-scale

0.458

High

537355

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

537356

TKT1
Transketolase 1

1

0

High-throughput

0.458

High

537363

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

537366

GID7
Glucose-induced degradation protein 7

1

0

High-throughput

0.458

High

537368

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

537373

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.458

High

537374

EF2
Elongation factor 2

1

0

High-throughput

0.458

High

537377

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.458

High

537378

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

537384

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

537386

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.458

High

537387

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

537390

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

537392

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.458

High

537393

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

537394

YPT52
GTP-binding protein YPT52

1

0

High-throughput

0.458

High

537398

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

537403

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.458

High

537404

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

537407

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

537408

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.458

High

537411

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

537412

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

537416

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

537424

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

537425

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

537427

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.458

High

537432

MMF1
Protein MMF1, mitochondrial

1

0

High-throughput

0.458

High

537435

MLP2
Protein MLP2

1

0

High-throughput

0.458

High

537436

TM108
Protein TMA108

1

0

High-throughput

0.458

High

537438

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

537441

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.458

High

537442

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.458

High

537443

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

High-throughput

0.458

High

537450

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

537452

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

537457

VID30
Vacuolar import and degradation protein 30

1

0

High-throughput

0.458

High

537461

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

537467

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

537471

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

537475

COFI
Cofilin

1

0

High-throughput

0.458

High

537476

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

537484

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.458

High

537489

ZEO1
Protein ZEO1

1

0

High-throughput

0.458

High

537492

SGO1
Shugoshin

1

0

High-throughput

0.458

High

537493

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

537494

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

537497

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

537400

AP3M
AP-3 complex subunit mu

1

1

High-throughput

0.457

High

537406

ARPC1
Actin-related protein 2/3 complex subunit 1

1

1

High-throughput

0.457

High

449882

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

537342

HSP26
Heat shock protein 26

1

1

High-throughput

0.445

High

537372

PUS3
tRNA pseudouridine(38/39) synthase

1

1

High-throughput

0.445

High

537380

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

537421

XDJ1
DnaJ protein homolog XDJ1

1

2

High-throughput

0.445

High

537428

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.445

High

537502

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

474275

YK104
Putative uncharacterized protein YKR104W

1

1

High-throughput

0.439

High

537481

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

537506

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

537344

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

537367

BUB2
Mitotic check point protein BUB2

1

0

High-throughput

0.426

High

537369

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.426

High

537383

GLRX4
Monothiol glutaredoxin-4

1

0

High-throughput

0.426

High

537401

SEA4
SEH-associated protein 4

1

0

High-throughput

0.426

High

537405

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.426

High

537415

TVP23
Golgi apparatus membrane protein TVP23

1

0

High-throughput

0.426

High

537429

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

537434

ATM1
Iron-sulfur clusters transporter ATM1, mitochondrial

1

0

High-throughput

0.426

High

537448

LSB3
LAS seventeen-binding protein 3

1

0

High-throughput

0.426

High

537454

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.426

High

537460

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.426

High

537465

FMP41
Uncharacterized mitochondrial hydrolase FMP41

1

0

High-throughput

0.426

High

537472

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.426

High

537500

NCE2
Non-classical export protein 2

1

0

High-throughput

0.426

High

537507

FOLD
Dihydrofolate synthetase

1

0

High-throughput

0.426

High

537490

MED7
Mediator of RNA polymerase II transcription subunit 7

2

0

High-throughput

0.307

High

537439

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.298

High

537469

SLG1
Protein SLG1

1

0

Small-scale

0.288

High

537423

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.282

High

537354

NUP1
Nucleoporin NUP1

1

0

High-throughput

0.279

Low

537397

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

537399

TAF5
Transcription initiation factor TFIID subunit 5

1

0

High-throughput

0.279

Low

537413

SPT8
Transcription factor SPT8

1

0

High-throughput

0.279

Low

537479

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.279

Low

537483

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.279

Low

537508

SUS1
Transcription and mRNA export factor SUS1

1

0

High-throughput

0.279

Low

537430

SHO1
High osmolarity signaling protein SHO1

1

0

Small-scale

0.269

Low

429607

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.261

Low

537352

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.261

Low

537358

VAN1
Mannan polymerase I complex VAN1 subunit

1

0

High-throughput

0.261

Low

537361

CDC10
Cell division control protein 10

1

0

High-throughput

0.261

Low

537364

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.261

Low

537385

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

537396

SWD2
COMPASS component SWD2

1

0

High-throughput

0.261

Low

537417

TEM1
Protein TEM1

1

0

High-throughput

0.261

Low

537418

DUN1
DNA damage response protein kinase DUN1

1

0

High-throughput

0.261

Low

537482

ERB1
Ribosome biogenesis protein ERB1

1

0

High-throughput

0.261

Low

537503

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.261

Low

537395

MID2
Cell wall integrity sensor MID2

1

0

Small-scale

0.251

Low

537473

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.251

Low

537347

PDI
Protein disulfide-isomerase

1

0

High-throughput

0.249

Low

537357

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

537370

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

537371

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

537389

IXR1
Intrastrand cross-link recognition protein

1

0

Small-scale

0.249

Low

537409

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.249

Low

537414

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

537440

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

537445

SET4
SET domain-containing protein 4

1

0

Small-scale

0.249

Low

537451

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

537453

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

537458

ERV14
ER-derived vesicles protein ERV14

1

0

High-throughput

0.249

Low

537468

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low

537478

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

537485

PEX30
Peroxisomal membrane protein PEX30

1

0

Small-scale

0.249

Low

537486

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

537495

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.249

Low

537496

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

537501

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.249

Low

537410

NPR3
Nitrogen permease regulator 3

1

0

High-throughput

0.232

Low

537420

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

537426

NPR2
Nitrogen permease regulator 2

1

0

High-throughput

0.232

Low

537433

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.232

Low

537437

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low

537446

EMP47
Protein EMP47

1

0

High-throughput

0.232

Low

537455

SPT20
Transcription factor SPT20

1

0

High-throughput

0.232

Low

537498

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

0

Small-scale

0.232

Low

537499

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

High-throughput

0.232

Low

537505

PEX11
Peroxisomal membrane protein PMP27

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024