Protein: MS116
ATP-dependent RNA helicase MSS116, mitochondrial (EC 3.6.4.13)

Gene: MS116, MSS116
Organism: Saccharomyces cerevisiae S288C
Interactions: 154
UniProt ID: P15424

Gene Ontology (top 5):
GO:0000372 - Group I intron splicing
GO:0000373 - Group II intron splicing
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000963 - mitochondrial RNA processing
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548402

CIC1
Proteasome-interacting protein CIC1

1

5

High-throughput

0.691

High

548350

XRN1
5'-3' exoribonuclease 1

3

7

Small-scale

0.640

High

548362

SPB4
ATP-dependent rRNA helicase SPB4

1

16

High-throughput

0.618

High

548403

DHH1
ATP-dependent RNA helicase DHH1

1

17

High-throughput

0.618

High

548422

MRH4
ATP-dependent RNA helicase MRH4, mitochondrial

1

15

Small-scale

0.618

High

548442

DHR1
Probable ATP-dependent RNA helicase DHR1

1

13

High-throughput

0.618

High

548386

RM03
Large ribosomal subunit protein mL44

1

0

High-throughput

0.586

High

548374

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

2

High-throughput

0.584

High

548351

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

6

High-throughput

0.553

High

527171

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

Small-scale

0.537

High

548426

BRE5
UBP3-associated protein BRE5

1

10

High-throughput

0.536

High

548430

NOP13
Nucleolar protein 13

1

10

High-throughput

0.536

High

548448

ESF1
Pre-rRNA-processing protein ESF1

1

4

High-throughput

0.536

High

548453

NOP6
Nucleolar protein 6

1

2

High-throughput

0.536

High

548353

SIS1
Protein SIS1

2

8

High-throughput

0.521

High

548381

RSSA1
Small ribosomal subunit protein uS2A

2

12

High-throughput

0.521

High

548348

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.513

High

548406

SERA
D-3-phosphoglycerate dehydrogenase 1

1

4

High-throughput

0.494

High

548366

MIG1
Regulatory protein MIG1

1

8

High-throughput

0.489

High

141123

RS9A
Small ribosomal subunit protein uS4A

1

9

High-throughput

0.479

High

376614

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

10

Small-scale

0.479

High

382919

RL25
Large ribosomal subunit protein uL23

1

8

High-throughput

0.479

High

402867

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

3

Small-scale

0.479

High

405394

RL26A
Large ribosomal subunit protein uL24A

1

10

High-throughput

0.479

High

406741

RS3
Small ribosomal subunit protein uS3

1

7

High-throughput

0.479

High

407690

RS13
Small ribosomal subunit protein uS15

1

7

High-throughput

0.479

High

410294

SC160
Protein SCP160

1

10

High-throughput

0.479

High

413272

RS14A
Small ribosomal subunit protein uS11A

1

8

High-throughput

0.479

High

424036

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

Small-scale

0.479

High

425729

RS19A
Small ribosomal subunit protein eS19A

1

10

High-throughput

0.479

High

477856

HSP77
Import motor subunit, mitochondrial

1

10

High-throughput

0.479

High

479890

RS6A
Small ribosomal subunit protein eS6A

1

10

High-throughput

0.479

High

482049

RS18A
Small ribosomal subunit protein uS13A

1

6

High-throughput

0.479

High

485442

SSBP1
Single-stranded nucleic acid-binding protein

1

9

High-throughput

0.479

High

543112

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

548355

RRP43
Exosome complex component RRP43

1

4

High-throughput

0.479

High

548356

RS2
Small ribosomal subunit protein uS5

1

10

High-throughput

0.479

High

548358

KRR1
KRR1 small subunit processome component

1

9

High-throughput

0.479

High

548361

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

High-throughput

0.479

High

548365

RS7A
Small ribosomal subunit protein eS7A

1

6

High-throughput

0.479

High

548370

RM09
Large ribosomal subunit protein uL3m

1

8

High-throughput

0.479

High

548373

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

15

High-throughput

0.479

High

548376

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

17

High-throughput

0.479

High

548380

RM06
Large ribosomal subunit protein uL6m

1

2

High-throughput

0.479

High

548382

HSP78
Heat shock protein 78, mitochondrial

1

7

High-throughput

0.479

High

548384

RM38
Large ribosomal subunit protein uL14m

1

1

High-throughput

0.479

High

548385

RS27A
Small ribosomal subunit protein eS27A

1

6

High-throughput

0.479

High

548387

RM07
Large ribosomal subunit protein uL5m

1

5

High-throughput

0.479

High

548401

RS20
Small ribosomal subunit protein uS10

1

9

High-throughput

0.479

High

548407

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.479

High

548413

UTP10
U3 small nucleolar RNA-associated protein 10

1

6

High-throughput

0.479

High

548415

LSM1
Sm-like protein LSm1

1

5

High-throughput

0.479

High

548419

RL4P
Large ribosomal subunit protein uL4m

1

2

High-throughput

0.479

High

548420

RMD9
RNA-binding protein RMD9, mitochondrial

1

1

High-throughput

0.479

High

548423

EIF2A
Eukaryotic translation initiation factor 2A

1

5

High-throughput

0.479

High

548427

GIS2
Zinc finger protein GIS2

1

8

High-throughput

0.479

High

548429

RM22
Large ribosomal subunit protein uL22m

1

3

High-throughput

0.479

High

548431

ORC1
Origin recognition complex subunit 1

1

6

High-throughput

0.479

High

548433

RS15
Small ribosomal subunit protein uS19

1

7

High-throughput

0.479

High

548437

XRN2
5'-3' exoribonuclease 2

1

7

High-throughput

0.479

High

548440

RT17
Small ribosomal subunit protein uS17m

1

4

High-throughput

0.479

High

548441

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

548456

RS10A
Small ribosomal subunit protein eS10A

1

9

High-throughput

0.479

High

548457

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.479

High

548458

YRA1
RNA annealing protein YRA1

1

13

High-throughput

0.479

High

548459

RM23
Large ribosomal subunit protein uL13m

1

9

High-throughput

0.479

High

357193

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

371008

CBP2
Cytochrome B pre-mRNA-processing protein 2

1

0

High-throughput

0.458

High

446102

MYO1
Myosin-1

1

0

Small-scale

0.458

High

520461

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.458

High

534445

RM31
Large ribosomal subunit protein mL60

1

0

High-throughput

0.458

High

548349

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.458

High

548352

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.458

High

548354

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.458

High

548359

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.458

High

548360

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.458

High

548372

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

548375

PT309
Pentatricopeptide repeat-containing protein PET309, mitochondrial

1

0

Small-scale

0.458

High

548378

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.458

High

548379

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

548388

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.458

High

548389

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.458

High

548390

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.458

High

548391

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.458

High

548392

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.458

High

548393

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.458

High

548394

RM36
Large ribosomal subunit protein bL31m

1

0

High-throughput

0.458

High

548395

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.458

High

548396

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.458

High

548397

RM40
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.458

High

548405

MRX1
MIOREX complex component 1

1

0

High-throughput

0.458

High

548408

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

0

High-throughput

0.458

High

548409

RRG9
Required for respiratory growth protein 9, mitochondrial

1

0

High-throughput

0.458

High

548412

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.458

High

548421

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.458

High

548425

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.458

High

548435

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.458

High

548439

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.458

High

548443

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.458

High

548445

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.458

High

548446

RRG8
Required for respiratory growth protein 8, mitochondrial

1

0

High-throughput

0.458

High

548449

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

548451

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.458

High

548434

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.457

High

548454

RTC1
Restriction of telomere capping protein 1

1

15

High-throughput

0.457

High

342843

ENO2
Enolase 2

1

3

High-throughput

0.445

High

365716

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

367688

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

404483

RL7A
Large ribosomal subunit protein uL30A

1

11

High-throughput

0.445

High

406285

RL15A
Large ribosomal subunit protein eL15A

1

3

High-throughput

0.445

High

479408

RS24A
Small ribosomal subunit protein eS24A

1

5

High-throughput

0.445

High

490219

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

493104

HSP72
Heat shock protein SSA2

1

16

High-throughput

0.445

High

534872

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.445

High

548357

GBP2
Serine/arginine

1

7

High-throughput

0.445

High

548364

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.445

High

548369

RL8B
Large ribosomal subunit protein eL8B

1

15

High-throughput

0.445

High

548371

HS104
Heat shock protein 104

1

6

High-throughput

0.445

High

548377

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

548417

RL4B
Large ribosomal subunit protein uL4B

1

9

High-throughput

0.445

High

548418

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.445

High

548436

RL6A
Large ribosomal subunit protein eL6A

1

6

High-throughput

0.445

High

548444

RRP5
rRNA biogenesis protein RRP5

1

12

High-throughput

0.445

High

355327

H2B1
Histone H2B.1

1

6

High-throughput

0.437

High

355762

H2B2
Histone H2B.2

1

6

High-throughput

0.437

High

357851

RS17A
Small ribosomal subunit protein eS17A

1

8

High-throughput

0.437

High

392274

H2A2
Histone H2A.2

1

6

High-throughput

0.437

High

470826

RS22A
Small ribosomal subunit protein uS8A

1

8

High-throughput

0.437

High

471989

RL31A
Large ribosomal subunit protein eL31A

1

13

High-throughput

0.437

High

480446

RS8A
Small ribosomal subunit protein eS8A

1

8

High-throughput

0.437

High

524136

CAF20
Cap-associated protein CAF20

1

4

High-throughput

0.437

High

548367

TF2B
Transcription initiation factor IIB

1

8

High-throughput

0.437

High

548368

BMH1
Protein BMH1

1

10

High-throughput

0.437

High

548383

RS3A1
Small ribosomal subunit protein eS1A

1

8

High-throughput

0.437

High

548398

GBLP
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.437

High

548400

NU170
Nucleoporin NUP170

1

3

High-throughput

0.437

High

548404

LAA1
AP-1 accessory protein LAA1

1

7

High-throughput

0.437

High

548410

ULP2
Ubiquitin-like-specific protease 2

1

5

High-throughput

0.437

High

548411

DSN1
Kinetochore-associated protein DSN1

1

6

High-throughput

0.437

High

548416

RS12
Small ribosomal subunit protein eS12

1

6

High-throughput

0.437

High

548432

H3
Histone H3

1

16

High-throughput

0.437

High

548438

LGE1
Transcriptional regulatory protein LGE1

1

3

High-throughput

0.437

High

548447

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

4

High-throughput

0.437

High

548452

VAM6
Vacuolar morphogenesis protein 6

1

6

High-throughput

0.437

High

548455

SGO1
Shugoshin

1

6

High-throughput

0.437

High

334601

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

399314

RLA0
Large ribosomal subunit protein uL10

1

7

High-throughput

0.407

High

535177

RS17B
Small ribosomal subunit protein eS17B

1

8

High-throughput

0.407

High

548363

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.407

High

548414

RL17B
Large ribosomal subunit protein uL22B

1

7

High-throughput

0.407

High

548450

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

4

High-throughput

0.407

High

548428

ELOA1
Elongin-A

1

0

High-throughput

0.279

Low

548424

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.249

Low

548399

SEA4
SEH-associated protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024