Protein: FAS2
Fatty acid synthase subunit alpha (EC 2.3.1.86) [Includes: Acyl carrier; 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (Beta-ketoacyl reductase); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) (Beta-ketoacyl synthase)]

Gene: FAS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 120
UniProt ID: P19097

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004312 - fatty acid synthase activity
GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004321 - fatty-acyl-CoA synthase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

421570

FAS1
Fatty acid synthase subunit beta

8

5

Small-scale

0.967

High

580509

FAS2
Fatty acid synthase subunit alpha

2

12

Small-scale

0.737

High

580565

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

0

High-throughput

0.613

High

580515

SIS1
Protein SIS1

2

2

High-throughput

0.601

High

580543

ATG8
Autophagy-related protein 8

2

5

Small-scale

0.584

High

365758

HSP82
ATP-dependent molecular chaperone HSP82

2

4

High-throughput

0.571

High

510203

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.571

High

580519

MAS5
Mitochondrial protein import protein MAS5

2

2

High-throughput

0.571

High

490282

HSP71
Heat shock protein SSA1

2

3

High-throughput

0.552

High

580525

HS104
Heat shock protein 104

2

0

High-throughput

0.547

High

580529

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.536

High

580557

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.536

High

580579

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

580574

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

580550

YCFI
Metal resistance protein YCF1

1

1

High-throughput

0.494

High

425748

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

543157

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

580512

HSP74
Heat shock protein SSA4

1

3

High-throughput

0.479

High

580530

HFA1
Acetyl-CoA carboxylase, mitochondrial

1

2

High-throughput

0.479

High

580541

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

580578

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.479

High

141139

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

357869

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

375263

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

382939

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

402880

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

Small-scale

0.458

High

405416

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

406763

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

407711

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413291

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

419798

SNF1
Carbon catabolite-derepressing protein kinase

1

0

Small-scale

0.458

High

425588

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.458

High

470849

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

472006

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

479909

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

480466

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

482068

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

580511

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

580518

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

580521

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

580522

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

580531

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

580532

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

580534

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

580539

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

580544

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

580546

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

580549

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

580552

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

580561

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.458

High

580563

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

580568

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

580571

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

580573

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

580577

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

580581

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

580585

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

580589

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

580591

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

580593

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

580600

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

493153

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

580526

APE2
Aminopeptidase 2, mitochondrial

1

1

High-throughput

0.445

High

580553

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

580575

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.445

High

580595

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.439

High

410303

SC160
Protein SCP160

1

1

High-throughput

0.437

High

580523

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

580524

BMH1
Protein BMH1

1

1

Small-scale

0.437

High

580527

HOG1
Mitogen-activated protein kinase HOG1

1

3

High-throughput

0.437

High

580535

BMH2
Protein BMH2

1

1

Small-scale

0.437

High

580547

ECM29
Proteasome component ECM29

1

1

High-throughput

0.437

High

580548

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.437

High

580551

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.437

High

580558

TM108
Protein TMA108

1

1

High-throughput

0.437

High

580583

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.437

High

580584

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

580596

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

580514

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.426

High

580516

YCP4
Flavoprotein-like protein YCP4

1

0

High-throughput

0.426

High

580517

LSB5
LAS seventeen-binding protein 5

1

0

High-throughput

0.426

High

409944

NOT3
General negative regulator of transcription subunit 3

2

0

High-throughput

0.307

High

580586

UFO1
Ubiquitin ligase complex F-box protein UFO1

1

0

Small-scale

0.292

High

580582

YMY9
Glucose-6-phosphate 1-epimerase

1

0

High-throughput

0.279

Low

580597

NOP58
Nucleolar protein 58

1

0

High-throughput

0.279

Low

580576

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

1

0

High-throughput

0.269

Low

580510

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

Small-scale

0.249

Low

580513

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

580520

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.249

Low

580533

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.249

Low

580536

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

580537

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

580538

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.249

Low

580540

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.249

Low

580545

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

580556

FTR1
Plasma membrane iron permease

1

0

High-throughput

0.249

Low

580559

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

580560

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

580562

MID1
Stretch-activated cation channel MID1

1

0

Small-scale

0.249

Low

580564

SET4
SET domain-containing protein 4

1

0

Small-scale

0.249

Low

580569

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

580572

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

580580

MDM1
Structural protein MDM1

1

0

Small-scale

0.249

Low

580587

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

580588

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

580592

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.249

Low

580594

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

580601

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

561211

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.232

Low

580528

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.232

Low

580542

SEA4
SEH-associated protein 4

1

0

High-throughput

0.232

Low

580554

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

580555

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

High-throughput

0.232

Low

580566

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

580567

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.232

Low

580570

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

580590

AB140
tRNA(Thr)

1

0

High-throughput

0.232

Low

580598

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low

580599

H2AZ
Histone H2A.Z

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024