Protein: MYO2
Myosin-2 (Cell division control protein 66) (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2)

Gene: MYO2
Organism: Saccharomyces cerevisiae S288C
Interactions: 185
UniProt ID: P19524

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0000131 - incipient cellular bud site
GO:0000132 - establishment of mitotic spindle orientation
GO:0000146 - microfilament motor activity
GO:0000329 - fungal-type vacuole membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

585348

MLC1
Myosin light chain 1

13

17

Small-scale

0.981

High

420223

CALM
Calmodulin

7

11

Small-scale

0.973

High

429168

SEC4
Ras-related protein SEC4

6

10

Small-scale

0.956

High

585341

YPT11
GTP-binding protein YPT11

5

12

Small-scale

0.923

High

585248

MYO2
Myosin-2

4

16

Small-scale

0.885

High

585346

YPT32
GTP-binding protein YPT32/YPT11

3

9

Small-scale

0.873

High

585356

ACT
Actin

3

16

Small-scale

0.865

High

585306

YPT31
GTP-binding protein YPT31/YPT8

3

9

Small-scale

0.865

High

446110

MYO1
Myosin-1

2

19

High-throughput

0.802

High

585360

RHO3
GTP-binding protein RHO3

2

7

Small-scale

0.786

High

585274

SMY1
Kinesin-related protein SMY1

11

8

Small-scale

0.755

High

585261

VAC17
vacuole-related protein 17

10

0

Small-scale

0.722

High

585345

SHE4
SWI5-dependent HO expression protein 4

5

1

Small-scale

0.713

High

585388

SRO7
Lethal(2) giant larvae protein homolog SRO7

4

1

Small-scale

0.694

High

585368

INP2
Inheritance of peroxisomes protein 2

5

0

Small-scale

0.693

High

585278

KAR9
Karyogamy protein KAR9

5

0

Small-scale

0.685

High

585376

MMR1
Mitochondrial MYO2 receptor-related protein 1

4

0

Small-scale

0.673

High

585254

SPA2
Protein SPA2

3

5

Small-scale

0.642

High

585270

XPO1
Exportin-1

2

1

Small-scale

0.614

High

585324

MAM33
Mitochondrial acidic protein MAM33

3

1

High-throughput

0.604

High

585332

NMD5
Nonsense-mediated mRNA decay protein 5

2

0

High-throughput

0.595

High

585268

BMH1
Protein BMH1

2

3

Small-scale

0.584

High

585315

RGA1
Rho-type GTPase-activating protein 1

2

4

Small-scale

0.584

High

585394

GYP5
GTPase-activating protein GYP5

2

2

Small-scale

0.584

High

585252

SEC15
Exocyst complex component SEC15

1

2

Small-scale

0.573

High

585379

PEX19
Peroxisomal membrane protein import receptor PEX19

1

3

Small-scale

0.573

High

365763

HSP82
ATP-dependent molecular chaperone HSP82

2

10

High-throughput

0.571

High

585255

NAP1
Nucleosome assembly protein

2

3

High-throughput

0.571

High

498433

METK1
S-adenosylmethionine synthase 1

2

0

High-throughput

0.563

High

425591

KAPR
cAMP-dependent protein kinase regulatory subunit

1

6

Small-scale

0.561

High

585299

DYHC
Dynein heavy chain, cytoplasmic

2

0

Small-scale

0.559

High

493162

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

510211

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

585321

PEA2
Protein PEA2

1

0

Small-scale

0.549

High

585289

GCN1
eIF-2-alpha kinase activator GCN1

2

6

High-throughput

0.537

High

585331

RRP41
Exosome complex component SKI6

2

1

High-throughput

0.537

High

585351

RRP46
Exosome complex component RRP46

2

1

High-throughput

0.537

High

585392

RRP42
Exosome complex component RRP42

2

1

High-throughput

0.537

High

585251

PWP1
Periodic tryptophan protein 1

1

7

High-throughput

0.536

High

585269

MCM5
Minichromosome maintenance protein 5

1

6

High-throughput

0.536

High

585285

SWE1
Mitosis inhibitor protein kinase SWE1

1

13

High-throughput

0.536

High

585287

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.536

High

585307

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

12

High-throughput

0.536

High

585316

PEX7
Peroxisomal targeting signal 2 receptor

1

4

High-throughput

0.536

High

585355

ARK1
Actin-regulating kinase 1

1

5

High-throughput

0.536

High

585362

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

8

High-throughput

0.536

High

585382

RBX1
RING-box protein HRT1

1

8

High-throughput

0.536

High

585349

MPS2
Monopolar spindle protein 2

1

0

Small-scale

0.529

High

585256

SIS1
Protein SIS1

2

2

High-throughput

0.521

High

585257

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

7

High-throughput

0.515

High

585273

SSH4
Protein SSH4

1

1

High-throughput

0.515

High

585326

BUB1
Checkpoint serine/threonine-protein kinase BUB1

1

7

High-throughput

0.515

High

585340

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.515

High

585344

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

11

High-throughput

0.515

High

585350

CUL3
Cullin-3

1

4

High-throughput

0.515

High

585354

FAP1
FKBP12-associated protein 1

1

3

High-throughput

0.515

High

585366

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.515

High

585290

MKS1
Negative regulator of RAS-cAMP pathway

1

0

High-throughput

0.513

High

585398

DCP1
mRNA-decapping enzyme subunit 1

1

0

Small-scale

0.504

High

585377

CORO
Coronin-like protein

1

7

Small-scale

0.501

High

585327

BUD6
Bud site selection protein 6

1

0

High-throughput

0.493

High

585372

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.493

High

585397

KCS1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.493

High

585293

SPT7
Transcriptional activator SPT7

1

8

High-throughput

0.489

High

585303

TAF5
Transcription initiation factor TFIID subunit 5

1

3

High-throughput

0.489

High

585367

GCN5
Histone acetyltransferase GCN5

1

6

High-throughput

0.489

High

585337

SGM1
Protein SGM1

1

19

Small-scale

0.481

High

585304

SRO77
Lethal(2) giant larvae protein homolog SRO77

1

1

Small-scale

0.481

High

585311

KEL1
Kelch repeat-containing protein 1

1

11

High-throughput

0.481

High

585318

SNF7
Vacuolar-sorting protein SNF7

1

3

High-throughput

0.481

High

585343

KEL2
Kelch repeat-containing protein 2

1

10

Small-scale

0.481

High

585374

SPH1
Protein SPH1

1

1

Small-scale

0.481

High

585266

PEX3
Peroxisomal biogenesis factor 3

1

0

Small-scale

0.480

High

585384

MCA1
Metacaspase-1

1

0

Small-scale

0.480

High

339424

CDK1
Cyclin-dependent kinase 1

1

7

High-throughput

0.479

High

407712

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

410304

SC160
Protein SCP160

1

1

High-throughput

0.479

High

543165

HSC82
ATP-dependent molecular chaperone HSC82

1

10

High-throughput

0.479

High

585272

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

585277

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.479

High

585280

SEC6
Exocyst complex component SEC6

1

1

Small-scale

0.479

High

585281

SEC8
Exocyst complex component SEC8

1

1

Small-scale

0.479

High

585286

SEC3
Exocyst complex component SEC3

1

11

Small-scale

0.479

High

585291

UBX1
UBX domain-containing protein 1

1

2

Small-scale

0.479

High

585292

BMH2
Protein BMH2

1

3

Small-scale

0.479

High

585300

SHE2
SWI5-dependent HO expression protein 2

1

1

High-throughput

0.479

High

585302

GBLP
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.479

High

585308

RCK2
Serine/threonine-protein kinase RCK2

1

6

High-throughput

0.479

High

585317

DHH1
ATP-dependent RNA helicase DHH1

1

1

Small-scale

0.479

High

585323

TM108
Protein TMA108

1

1

High-throughput

0.479

High

585361

NUM1
Nuclear migration protein NUM1

1

19

High-throughput

0.479

High

585363

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

585369

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

585381

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

585387

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

585391

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

585396

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

145900

YO304
Uncharacterized protein YOR304C-A

1

0

Small-scale

0.460

High

409945

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.460

High

585330

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.460

High

585370

VPS64
Vacuolar protein sorting-associated protein 64

1

0

High-throughput

0.460

High

141142

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

406766

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

482071

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

524157

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

535976

CHS2
Chitin synthase 2

1

0

Small-scale

0.458

High

585249

EXO70
Exocyst complex component EXO70

1

0

Small-scale

0.458

High

585258

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

585283

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

585284

STE5
Protein STE5

1

0

Small-scale

0.458

High

585296

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

585305

EXO84
Exocyst complex component EXO84

1

0

Small-scale

0.458

High

585309

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

585310

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

585334

LSM1
Sm-like protein LSm1

1

0

Small-scale

0.458

High

585338

TTI2
TEL2-interacting protein 2

1

0

High-throughput

0.458

High

585342

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

585347

MDM34
Mitochondrial distribution and morphology protein 34

1

0

Small-scale

0.458

High

585353

INN1
Ingression protein 1

1

0

Small-scale

0.458

High

585358

SEC5
Exocyst complex component SEC5

1

0

Small-scale

0.458

High

585371

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

585375

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.458

High

585383

SGO1
Shugoshin

1

0

High-throughput

0.458

High

585385

AB140
tRNA(Thr)

1

0

High-throughput

0.458

High

490290

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

540522

CYPH
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.445

High

585275

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

3

High-throughput

0.445

High

585276

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.445

High

585279

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

585298

LHS1
Heat shock protein 70 homolog LHS1

1

6

High-throughput

0.445

High

585312

SET5
Histone-lysine N-methyltransferase SET5

1

3

High-throughput

0.445

High

585319

VAC8
Vacuolar protein 8

1

5

Small-scale

0.445

High

585322

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

585329

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.445

High

585393

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

585271

ZIP1
Synaptonemal complex protein ZIP1

1

13

High-throughput

0.439

High

382941

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

470852

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

472008

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

480468

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

557860

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

585267

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

585288

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

585297

CENPA
Histone H3-like centromeric protein CSE4

1

4

High-throughput

0.437

High

585357

H3
Histone H3

1

4

High-throughput

0.437

High

585386

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

585389

ATG9
Autophagy-related protein 9

1

2

High-throughput

0.437

High

367723

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

585259

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

585301

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.426

High

585352

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

585373

BCH1
Protein BCH1

1

0

High-throughput

0.426

High

585250

NUP1
Nucleoporin NUP1

1

5

High-throughput

0.417

High

541612

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.407

High

585265

SPT5
Transcription elongation factor SPT5

1

2

High-throughput

0.407

High

585325

DJP1
DnaJ-like protein 1

1

2

High-throughput

0.407

High

585339

HLJ1
Protein HLJ1

1

3

High-throughput

0.407

High

585380

BRE1
E3 ubiquitin-protein ligase BRE1

1

19

High-throughput

0.407

High

585336

NNF1
Kinetochore-associated protein NNF1

2

0

High-throughput

0.310

High

585359

CTR9
RNA polymerase-associated protein CTR9

2

0

High-throughput

0.307

High

585390

RRP6
Exosome complex exonuclease RRP6

2

0

High-throughput

0.307

High

585364

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.269

Low

585262

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

585395

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

357872

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

405418

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

413294

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

425752

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

479911

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

585253

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

585260

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

585263

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.249

Low

585264

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

585282

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

585294

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

585295

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

585328

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

Small-scale

0.249

Low

585333

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.249

Low

585335

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

585378

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

585313

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low

585314

SNF11
Transcription regulatory protein SNF11

1

0

High-throughput

0.232

Low

585320

GET2
Golgi to ER traffic protein 2

1

0

High-throughput

0.232

Low

585365

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024