Protein: EBP2
rRNA-processing protein EBP2 (EBNA1-binding protein homolog)

Gene: EBP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 179
UniProt ID: P36049

Gene Ontology (top 5):
GO:0000280 - nuclear division
GO:0003729 - mRNA binding
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0030687 - preribosome, large subunit precursor

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

731878

BRX1
Ribosome biogenesis protein BRX1

9

8

Small-scale

0.973

High

731796

RPF2
Ribosome biogenesis protein RPF2

11

1

Small-scale

0.973

High

731806

SSF1
Ribosome biogenesis protein SSF1

9

1

Small-scale

0.964

High

731891

SSF2
Ribosome biogenesis protein SSF2

2

1

High-throughput

0.767

High

731885

RRS1
Regulator of ribosome biosynthesis

9

1

Small-scale

0.749

High

731838

PESC
Pescadillo homolog

9

1

Small-scale

0.747

High

638712

SPB4
ATP-dependent rRNA helicase SPB4

7

4

High-throughput

0.738

High

731797

NOP4
Nucleolar protein 4

6

1

Small-scale

0.736

High

731807

RPF1
Ribosome production factor 1

2

0

High-throughput

0.720

High

731825

LOC1
60S ribosomal subunit assembly/export protein LOC1

8

0

Small-scale

0.720

High

731822

RLP7
Ribosome biogenesis protein RLP7

5

1

Small-scale

0.710

High

731877

NOP12
Nucleolar protein 12

5

1

Small-scale

0.705

High

731816

NUG1
Nuclear GTP-binding protein NUG1

5

1

High-throughput

0.704

High

731858

HAS1
ATP-dependent RNA helicase HAS1

5

4

High-throughput

0.704

High

731894

DBP10
ATP-dependent RNA helicase DBP10

4

2

High-throughput

0.696

High

731805

CIC1
Proteasome-interacting protein CIC1

4

1

High-throughput

0.694

High

731889

NOP53
Ribosome biogenesis protein NOP53

4

1

High-throughput

0.686

High

731814

NOC2
Nucleolar complex protein 2

5

0

Small-scale

0.681

High

731870

DBP9
ATP-dependent RNA helicase DBP9

4

3

Small-scale

0.680

High

731794

RRP14
Ribosomal RNA-processing protein 14

5

0

Small-scale

0.675

High

731832

NSA1
Ribosome biogenesis protein NSA1

5

0

Small-scale

0.672

High

731887

YTM1
Ribosome biogenesis protein YTM1

4

3

Small-scale

0.672

High

597821

PWP1
Periodic tryptophan protein 1

3

4

High-throughput

0.666

High

731818

NSA2
Ribosome biogenesis protein NSA2

4

0

High-throughput

0.661

High

731892

MAK21
Ribosome biogenesis protein MAK21

3

2

High-throughput

0.658

High

731844

NOP15
Ribosome biogenesis protein 15

3

1

High-throughput

0.650

High

731863

ERB1
Ribosome biogenesis protein ERB1

3

2

Small-scale

0.650

High

699666

DRS1
ATP-dependent RNA helicase DRS1

3

3

High-throughput

0.646

High

731799

MAK5
ATP-dependent RNA helicase MAK5

3

4

High-throughput

0.646

High

731810

FKBP3
Peptidyl-prolyl cis-trans isomerase

3

2

High-throughput

0.646

High

731868

FKBP4
FK506-binding protein 4

3

2

High-throughput

0.646

High

731875

NOC3
Nucleolar complex-associated protein 3

3

1

High-throughput

0.646

High

731823

NOP2
25S rRNA

3

2

Small-scale

0.640

High

731856

NOG1
Nucleolar GTP-binding protein 1

3

2

Small-scale

0.640

High

731834

CGR1
rRNA-processing protein CGR1

3

0

High-throughput

0.633

High

731899

RRP12
Ribosomal RNA-processing protein 12

3

0

High-throughput

0.633

High

731831

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

0

High-throughput

0.632

High

731793

EBP2
rRNA-processing protein EBP2

3

0

Small-scale

0.625

High

634393

SPB1
27S pre-rRNA

3

0

High-throughput

0.618

High

731815

NOP16
Nucleolar protein 16

3

0

High-throughput

0.618

High

731842

NOP13
Nucleolar protein 13

2

1

High-throughput

0.611

High

731801

YBC8
UPF0642 protein YBL028C

2

0

High-throughput

0.588

High

594029

MAK11
Protein MAK11

2

3

Small-scale

0.584

High

715421

RRP1
Ribosomal RNA-processing protein 1

2

1

Small-scale

0.584

High

731864

RRP5
rRNA biogenesis protein RRP5

2

1

Small-scale

0.584

High

731861

PUF6
Pumilio homology domain family member 6

2

1

Small-scale

0.571

High

731829

MPS3
Spindle pole body assembly component MPS3

1

0

Small-scale

0.568

High

383070

RL25
Large ribosomal subunit protein uL23

2

0

Small-scale

0.559

High

731803

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

731824

UTP10
U3 small nucleolar RNA-associated protein 10

2

0

High-throughput

0.559

High

731859

RRP17
Ribosomal RNA-processing protein 17

2

0

High-throughput

0.559

High

691366

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

3

High-throughput

0.541

High

731840

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.541

High

564263

RL8A
Large ribosomal subunit protein eL8A

2

3

Small-scale

0.535

High

731819

RL34B
Large ribosomal subunit protein eL34B

2

2

Small-scale

0.535

High

392393

H2A2
Histone H2A.2

2

3

High-throughput

0.533

High

490873

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.533

High

624063

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.518

High

731839

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

731853

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

731896

RRP36
rRNA biogenesis protein RRP36

1

0

Small-scale

0.513

High

731837

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.493

High

509417

CDC24
Cell division control protein 24

1

1

High-throughput

0.489

High

731849

RL34A
Large ribosomal subunit protein eL34A

1

2

Small-scale

0.481

High

731881

ULS1
ATP-dependent helicase ULS1

1

1

Small-scale

0.481

High

141260

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

404545

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.479

High

405549

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

480034

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

501206

MAK16
Protein MAK16

1

1

High-throughput

0.479

High

534945

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

644998

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

645190

RL16B
Large ribosomal subunit protein uL13B

1

2

High-throughput

0.479

High

703029

MRT4
Ribosome assembly factor MRT4

1

1

High-throughput

0.479

High

731795

DBP7
ATP-dependent RNA helicase DBP7

1

4

High-throughput

0.479

High

731811

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.479

High

731828

MTR4
ATP-dependent RNA helicase DOB1

1

2

Small-scale

0.479

High

731833

LSG1
Large subunit GTPase 1

1

1

Small-scale

0.479

High

731835

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

731846

RCM1
25S rRNA

1

2

High-throughput

0.479

High

731857

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

731869

JIP5
WD repeat-containing protein JIP5

1

2

High-throughput

0.479

High

731873

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

731879

REXO4
RNA exonuclease 4

1

1

High-throughput

0.479

High

731890

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

731897

NOP58
Nucleolar protein 58

1

1

High-throughput

0.479

High

731898

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

479447

RS24A
Small ribosomal subunit protein eS24A

1

1

High-throughput

0.470

High

615140

BUR1
Serine/threonine-protein kinase BUR1

1

1

High-throughput

0.470

High

731871

RGA2
Rho-type GTPase-activating protein 2

1

2

High-throughput

0.470

High

731802

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

407843

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413434

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

630182

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

631798

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

634555

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

635109

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

645369

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

680614

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

704315

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

710867

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

731804

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

731809

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

731836

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

731843

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.458

High

731845

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

731860

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

731862

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

731872

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

731876

RLP24
Ribosome biogenesis protein RLP24

1

0

High-throughput

0.458

High

731886

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.458

High

510894

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

145714

RL36B
Large ribosomal subunit protein eL36B

1

2

Small-scale

0.439

High

406121

RL36A
Large ribosomal subunit protein eL36A

1

2

Small-scale

0.439

High

605624

KIN3
Serine/threonine-protein kinase KIN3

1

1

High-throughput

0.439

High

728679

BDF1
Bromodomain-containing factor 1

1

3

High-throughput

0.439

High

355447

H2B1
Histone H2B.1

1

3

High-throughput

0.437

High

392101

H2A1
Histone H2A.1

1

3

High-throughput

0.437

High

472130

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

480599

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

481318

RL2A
Large ribosomal subunit protein uL2A

1

1

High-throughput

0.437

High

640904

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.437

High

661904

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

663845

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

667151

RL8B
Large ribosomal subunit protein eL8B

1

3

High-throughput

0.437

High

731798

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.437

High

731848

H3
Histone H3

1

2

High-throughput

0.437

High

731850

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

731851

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

731882

TMA16
Translation machinery-associated protein 16

2

0

High-throughput

0.310

High

731893

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

Small-scale

0.288

High

675955

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

731841

ELOA1
Elongin-A

1

0

High-throughput

0.279

Low

731852

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.279

Low

731883

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.279

Low

731813

OAF1
Oleate-activated transcription factor 1

1

0

High-throughput

0.269

Low

731867

YL455
PWWP domain-containing protein YLR455W

1

0

High-throughput

0.269

Low

731888

THP3
Protein THP3

1

0

High-throughput

0.269

Low

516867

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.265

Low

446147

MYO1
Myosin-1

1

0

High-throughput

0.251

Low

629711

STE50
Protein STE50

1

0

High-throughput

0.251

Low

634946

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

688873

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

702652

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

731800

RTG3
Retrograde regulation protein 3

1

0

High-throughput

0.251

Low

731808

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.251

Low

731817

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

731826

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.251

Low

731827

STB2
Protein STB2

1

0

High-throughput

0.251

Low

731865

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

731895

ERP3
Protein ERP3

1

0

High-throughput

0.251

Low

339573

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.249

Low

357996

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

406958

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

408329

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.249

Low

425877

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

470987

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

482196

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

524259

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

558000

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.249

Low

604537

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.249

Low

605975

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.249

Low

627918

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

688195

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

700335

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

706198

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

729840

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

731812

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

731820

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.249

Low

731821

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

731830

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

731847

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low

731854

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

731855

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

731866

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

731874

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

731880

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

731884

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024