Protein: IMB2
Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN)

Gene: IMB2, KAP104
Organism: Saccharomyces cerevisiae S288C
Interactions: 170
UniProt ID: P38217

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005643 - nuclear pore
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005934 - cellular bud tip

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

691992

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

12

2

Small-scale

0.761

High

746558

HRP1
Nuclear polyadenylated RNA-binding protein 4

10

7

Small-scale

0.757

High

698781

GSP1
GTP-binding nuclear protein GSP1/CNR1

6

17

Small-scale

0.731

High

746509

T2FB
Transcription initiation factor IIF subunit beta

3

1

Small-scale

0.672

High

707842

GCN1
eIF-2-alpha kinase activator GCN1

3

9

High-throughput

0.662

High

746536

STE20
Serine/threonine-protein kinase STE20

1

6

Small-scale

0.647

High

746501

IMB4
Importin subunit beta-4

3

13

High-throughput

0.643

High

746533

NU100
Nucleoporin NUP100/NSP100

3

20

Small-scale

0.640

High

746518

NUP57
Nucleoporin NUP57

2

20

Small-scale

0.628

High

746493

ECM29
Proteasome component ECM29

2

12

High-throughput

0.621

High

454297

TBA1
Tubulin alpha-1 chain

2

3

High-throughput

0.618

High

746545

IMB1
Importin subunit beta-1

1

12

High-throughput

0.618

High

746490

ENP1
Essential nuclear protein 1

2

0

Small-scale

0.606

High

392110

H2A1
Histone H2A.1

2

6

Small-scale

0.602

High

746519

NUP42
Nucleoporin NUP42

2

20

Small-scale

0.600

High

746537

CLU
Clustered mitochondria protein 1

2

0

High-throughput

0.595

High

366184

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.594

High

746520

NU145
Nucleoporin NUP145

2

20

Small-scale

0.586

High

360852

TBB
Tubulin beta chain

2

3

High-throughput

0.584

High

511067

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.584

High

543622

HSC82
ATP-dependent molecular chaperone HSC82

2

7

High-throughput

0.584

High

555992

VATB
V-type proton ATPase subunit B

2

3

High-throughput

0.584

High

680650

HS104
Heat shock protein 104

2

3

High-throughput

0.584

High

746534

NU116
Nucleoporin NUP116/NSP116

2

20

Small-scale

0.584

High

619568

MPCP
Mitochondrial phosphate carrier protein

2

3

High-throughput

0.565

High

746502

SSB2
Ribosome-associated molecular chaperone SSB2

2

9

High-throughput

0.552

High

392408

H2A2
Histone H2A.2

1

6

High-throughput

0.536

High

399436

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.536

High

407874

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.536

High

423678

ADR1
Regulatory protein ADR1

1

11

High-throughput

0.536

High

424478

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.536

High

491008

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.536

High

699003

GSP2
GTP-binding nuclear protein GSP2/CNR2

1

17

High-throughput

0.536

High

703041

MRT4
Ribosome assembly factor MRT4

1

2

High-throughput

0.536

High

746505

AYR1
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

1

1

High-throughput

0.536

High

746510

YRB1
Ran-specific GTPase-activating protein 1

1

20

High-throughput

0.536

High

746524

PRS10
26S proteasome subunit RPT4

1

4

High-throughput

0.536

High

746529

YND5
Uncharacterized WD repeat-containing protein YNL035C

1

12

High-throughput

0.536

High

746555

RTN2
Reticulon-like protein 2

1

2

High-throughput

0.536

High

688035

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

2

4

High-throughput

0.521

High

407508

RS9B
Small ribosomal subunit protein uS4B

1

2

High-throughput

0.515

High

389081

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

739484

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.513

High

744724

KTR3
Probable mannosyltransferase KTR3

1

0

High-throughput

0.513

High

746508

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.513

High

746515

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.513

High

746549

SYO1
Synchronized import protein 1

1

0

High-throughput

0.513

High

746556

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.513

High

595023

NUP1
Nucleoporin NUP1

1

20

Small-scale

0.508

High

355465

H2B1
Histone H2B.1

1

4

Small-scale

0.501

High

485514

SSBP1
Single-stranded nucleic acid-binding protein

1

6

Small-scale

0.501

High

498900

RL4A
Large ribosomal subunit protein uL4A

1

5

Small-scale

0.501

High

746496

RS14B
Small ribosomal subunit protein uS11B

1

3

Small-scale

0.501

High

746498

RS26A
Small ribosomal subunit protein eS26A

1

2

Small-scale

0.501

High

746527

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

Small-scale

0.501

High

746530

H3
Histone H3

1

15

Small-scale

0.501

High

746531

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

7

Small-scale

0.501

High

746547

TSR2
Pre-rRNA-processing protein TSR2

1

1

Small-scale

0.501

High

746548

ASR1
Alcohol-sensitive RING finger protein 1

1

2

Small-scale

0.501

High

746551

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

1

1

Small-scale

0.501

High

746552

POM33
Pore membrane protein of 33 kDa

1

2

Small-scale

0.501

High

746554

ARP8
Actin-like protein ARP8

1

2

Small-scale

0.501

High

334472

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.500

High

334925

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.500

High

342705

ENO1
Enolase 1

1

1

High-throughput

0.500

High

376762

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.500

High

378336

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.500

High

381701

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

1

High-throughput

0.500

High

389273

HXKA
Hexokinase-1

1

1

High-throughput

0.500

High

393557

PMA1
Plasma membrane ATPase 1

1

3

High-throughput

0.500

High

410982

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.500

High

423835

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.500

High

450024

HSP73
Heat shock protein SSA3

1

10

High-throughput

0.500

High

454597

TBA3
Tubulin alpha-3 chain

1

4

High-throughput

0.500

High

540080

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.500

High

657231

URA7
CTP synthase 1

1

1

High-throughput

0.500

High

660908

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

4

High-throughput

0.500

High

664795

BMH1
Protein BMH1

1

2

High-throughput

0.500

High

703784

PRS6B
26S proteasome regulatory subunit 6B homolog

1

1

High-throughput

0.500

High

746497

MET10
Sulfite reductase [NADPH] flavoprotein component

1

1

High-throughput

0.500

High

746539

RUVB1
RuvB-like protein 1

1

4

High-throughput

0.500

High

675262

LCF1
Long-chain-fatty-acid--CoA ligase 1

1

1

High-throughput

0.489

High

687639

OAC1
Mitochondrial oxaloacetate transport protein

1

1

High-throughput

0.489

High

746503

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

4

High-throughput

0.489

High

746540

YHM2
Citrate/oxoglutarate carrier protein

1

2

High-throughput

0.489

High

746557

TECR
Very-long-chain enoyl-CoA reductase

1

1

High-throughput

0.489

High

746532

NUP49
Nucleoporin NUP49/NSP49

1

20

Small-scale

0.481

High

389703

CDC25
Cell division control protein 25

1

0

Small-scale

0.480

High

746535

DIG1
Down-regulator of invasive growth 1

1

0

Small-scale

0.480

High

746538

ACL4
Assembly chaperone of RPL4

1

0

Small-scale

0.480

High

410791

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.479

High

425015

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.479

High

430771

SYV
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.479

High

440880

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.479

High

520966

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.479

High

537402

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

554631

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

588051

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.479

High

746492

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.479

High

141292

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

407001

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

413467

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

480631

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

485709

IF4A
ATP-dependent RNA helicase eIF4A

1

5

High-throughput

0.479

High

558027

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

606623

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

631835

RS2
Small ribosomal subunit protein uS5

1

2

Small-scale

0.479

High

662035

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

675994

XPO1
Exportin-1

1

8

High-throughput

0.479

High

688210

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

693624

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.479

High

694023

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

7

Small-scale

0.479

High

700857

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

706232

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

729871

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

746491

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

746512

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

5

High-throughput

0.479

High

746517

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

1

High-throughput

0.479

High

746525

HST2
NAD-dependent protein deacetylase HST2

1

10

High-throughput

0.479

High

746528

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

746541

LRS4
Monopolin complex subunit LRS4

1

1

Small-scale

0.479

High

746542

SXM1
Importin beta SMX1

1

8

High-throughput

0.479

High

746544

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

746550

SUB2
ATP-dependent RNA helicase SUB2

1

8

High-throughput

0.479

High

746553

RIO1
Serine/threonine-protein kinase RIO1

1

6

High-throughput

0.479

High

481902

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.458

High

746494

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

746499

FIR1
Factor interacting with REF2

1

0

High-throughput

0.458

High

448496

PRTB
Cerevisin

1

1

Small-scale

0.457

High

655702

PRP45
Pre-mRNA-processing protein 45

1

4

High-throughput

0.457

High

427235

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

High-throughput

0.457

High

746506

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

5

High-throughput

0.457

High

367990

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

389899

VDAC1
Mitochondrial outer membrane protein porin 1

1

1

High-throughput

0.445

High

478133

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.445

High

493785

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

605017

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.445

High

628964

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.445

High

633167

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

694563

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

705098

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

746511

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.445

High

746514

RSSA2
Small ribosomal subunit protein uS2B

1

5

High-throughput

0.445

High

746516

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.445

High

549385

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

Small-scale

0.437

High

690772

ERG1
Squalene epoxidase ERG1

1

2

High-throughput

0.437

High

704621

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

4

High-throughput

0.437

High

746504

ELO3
Fatty acid elongase 3

1

3

High-throughput

0.437

High

640921

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

576226

ERD2
ER lumen protein-retaining receptor

1

1

High-throughput

0.407

High

746500

PIC2
Mitochondrial phosphate carrier protein 2

1

1

High-throughput

0.407

High

746521

PHB2
Prohibitin-2

1

8

High-throughput

0.407

High

746522

ERG25
C-4 methylsterol oxidase ERG25

1

1

High-throughput

0.407

High

746543

PDR15
ATP-dependent permease PDR15

1

1

High-throughput

0.407

High

746507

LCB2
Serine palmitoyltransferase 2

2

0

High-throughput

0.324

High

746513

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

2

0

High-throughput

0.318

High

423992

CBP6
Cytochrome B pre-mRNA-processing protein 6

1

0

High-throughput

0.279

Low

486137

ADH4
Alcohol dehydrogenase 4

1

0

High-throughput

0.279

Low

549667

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.279

Low

561795

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.279

Low

575946

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.279

Low

655840

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.279

Low

689079

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.279

Low

696784

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.279

Low

733505

PET10
Protein PET10

1

0

High-throughput

0.279

Low

746495

PSD1
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial

1

0

High-throughput

0.279

Low

746546

TDA5
Uncharacterized oxidoreductase TDA5

1

0

High-throughput

0.269

Low

746526

BSC5
Bypass of stop codon protein 5

1

0

High-throughput

0.265

Low

696866

RML2
Large ribosomal subunit protein uL2m

1

0

Small-scale

0.261

Low

746523

YG1I
Uncharacterized membrane protein YGR026W

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024