Protein: RPF1
Ribosome production factor 1 (Ribosome biogenesis protein RPF1)

Gene: RPF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 163
UniProt ID: P38805

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000460 - maturation of 5.8S rRNA
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470 - maturation of LSU-rRNA

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

733817

RPF2
Ribosome biogenesis protein RPF2

5

1

Small-scale

0.908

High

754857

SSF1
Ribosome biogenesis protein SSF1

5

1

Small-scale

0.903

High

501215

MAK16
Protein MAK16

4

2

High-throughput

0.881

High

755342

BRX1
Ribosome biogenesis protein BRX1

3

5

High-throughput

0.848

High

755336

RRP15
Ribosomal RNA-processing protein 15

3

0

Small-scale

0.775

High

755308

NSA1
Ribosome biogenesis protein NSA1

8

2

Small-scale

0.749

High

755323

HAS1
ATP-dependent RNA helicase HAS1

6

4

High-throughput

0.729

High

731807

EBP2
rRNA-processing protein EBP2

2

0

High-throughput

0.720

High

755350

SSF2
Ribosome biogenesis protein SSF2

2

1

High-throughput

0.712

High

755312

NOP15
Ribosome biogenesis protein 15

5

2

High-throughput

0.712

High

755294

NOP2
25S rRNA

5

3

Small-scale

0.709

High

732213

RRP14
Ribosomal RNA-processing protein 14

2

0

High-throughput

0.699

High

755346

RRS1
Regulator of ribosome biosynthesis

2

0

High-throughput

0.699

High

755320

NOG1
Nucleolar GTP-binding protein 1

5

1

Small-scale

0.699

High

755287

NOC2
Nucleolar complex protein 2

6

0

High-throughput

0.695

High

754115

CIC1
Proteasome-interacting protein CIC1

4

3

High-throughput

0.687

High

755355

IF6
Eukaryotic translation initiation factor 6

5

0

Small-scale

0.684

High

755309

PESC
Pescadillo homolog

5

0

Small-scale

0.679

High

755293

RLP7
Ribosome biogenesis protein RLP7

4

2

Small-scale

0.678

High

744189

MAK5
ATP-dependent RNA helicase MAK5

3

4

High-throughput

0.670

High

755348

YTM1
Ribosome biogenesis protein YTM1

4

0

High-throughput

0.661

High

638747

SPB4
ATP-dependent rRNA helicase SPB4

3

4

High-throughput

0.656

High

755327

PUF6
Pumilio homology domain family member 6

4

0

Small-scale

0.649

High

634407

SPB1
27S pre-rRNA

3

1

High-throughput

0.646

High

715438

RRP1
Ribosomal RNA-processing protein 1

3

3

Small-scale

0.643

High

755298

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

0

High-throughput

0.622

High

699680

DRS1
ATP-dependent RNA helicase DRS1

2

3

High-throughput

0.611

High

755290

NUG1
Nuclear GTP-binding protein NUG1

2

1

High-throughput

0.611

High

594039

MAK11
Protein MAK11

3

0

Small-scale

0.606

High

755353

DBP10
ATP-dependent RNA helicase DBP10

3

0

High-throughput

0.606

High

404576

RL7A
Large ribosomal subunit protein uL30A

2

2

High-throughput

0.601

High

755351

MAK21
Ribosome biogenesis protein MAK21

2

3

High-throughput

0.594

High

748603

ENP1
Essential nuclear protein 1

2

1

High-throughput

0.584

High

141319

RS9A
Small ribosomal subunit protein uS4A

2

2

High-throughput

0.571

High

383133

RL25
Large ribosomal subunit protein uL23

2

1

High-throughput

0.571

High

480092

RS6A
Small ribosomal subunit protein eS6A

2

2

High-throughput

0.571

High

703048

MRT4
Ribosome assembly factor MRT4

2

2

High-throughput

0.571

High

755285

FKBP3
Peptidyl-prolyl cis-trans isomerase

2

2

High-throughput

0.571

High

755329

ERB1
Ribosome biogenesis protein ERB1

2

1

High-throughput

0.571

High

755332

FKBP4
FK506-binding protein 4

2

2

High-throughput

0.571

High

755334

DBP9
ATP-dependent RNA helicase DBP9

2

2

High-throughput

0.571

High

755339

NOC3
Nucleolar complex-associated protein 3

2

2

High-throughput

0.571

High

755301

URB2
Nucleolar pre-ribosomal-associated protein 2

2

0

High-throughput

0.569

High

645432

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.563

High

755324

RRP17
Ribosomal RNA-processing protein 17

2

0

High-throughput

0.559

High

407904

RS13
Small ribosomal subunit protein uS15

2

0

High-throughput

0.547

High

413494

RS14A
Small ribosomal subunit protein uS11A

2

0

High-throughput

0.547

High

755289

NOP16
Nucleolar protein 16

2

0

High-throughput

0.547

High

755291

NSA2
Ribosome biogenesis protein NSA2

2

0

High-throughput

0.547

High

755326

RRB1
Ribosome assembly protein RRB1

2

0

High-throughput

0.547

High

755347

NIP7
60S ribosome subunit biogenesis protein NIP7

2

0

High-throughput

0.547

High

755284

RPF1
Ribosome production factor 1

1

0

High-throughput

0.546

High

667173

RL8B
Large ribosomal subunit protein eL8B

1

3

High-throughput

0.536

High

676034

XPO1
Exportin-1

1

2

High-throughput

0.536

High

405610

RL26A
Large ribosomal subunit protein uL24A

2

4

High-throughput

0.521

High

407036

RS3
Small ribosomal subunit protein uS3

2

1

High-throughput

0.521

High

408354

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

2

2

High-throughput

0.521

High

425939

RS19A
Small ribosomal subunit protein eS19A

2

2

High-throughput

0.521

High

471044

RS22A
Small ribosomal subunit protein uS8A

2

2

High-throughput

0.521

High

478892

RL20B
Large ribosomal subunit protein eL20B

2

2

High-throughput

0.521

High

491149

HSP71
Heat shock protein SSA1

2

3

High-throughput

0.521

High

645024

RL16A
Large ribosomal subunit protein uL13A

2

2

High-throughput

0.521

High

700397

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.521

High

406130

RL36A
Large ribosomal subunit protein eL36A

1

2

High-throughput

0.514

High

481774

RS16B
Small ribosomal subunit protein uS9B

1

1

High-throughput

0.514

High

755307

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.513

High

755304

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.489

High

755318

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.481

High

755321

KA120
Importin beta-like protein KAP120

1

3

Small-scale

0.481

High

631866

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

634595

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.479

High

755297

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

755300

MTR4
ATP-dependent RNA helicase DOB1

1

1

Small-scale

0.479

High

755310

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.479

High

755314

RCM1
25S rRNA

1

3

High-throughput

0.479

High

755325

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

755328

UTP14
U3 small nucleolar RNA-associated protein 14

1

1

High-throughput

0.479

High

755333

JIP5
WD repeat-containing protein JIP5

1

1

High-throughput

0.479

High

755337

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

755340

RLP24
Ribosome biogenesis protein RLP24

1

1

High-throughput

0.479

High

755341

NOP12
Nucleolar protein 12

1

3

High-throughput

0.479

High

755349

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.479

High

755354

NOP58
Nucleolar protein 58

1

5

High-throughput

0.479

High

742013

NOP4
Nucleolar protein 4

1

0

High-throughput

0.458

High

746237

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

755311

NOP13
Nucleolar protein 13

1

0

High-throughput

0.458

High

477268

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.457

High

755288

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

Small-scale

0.457

High

755299

NMD5
Nonsense-mediated mRNA decay protein 5

1

3

Small-scale

0.457

High

755306

IMB5
Importin subunit beta-5

1

2

Small-scale

0.457

High

405184

RL17A
Large ribosomal subunit protein uL22A

1

2

High-throughput

0.445

High

481155

RL1A
Large ribosomal subunit protein uL1A

1

5

High-throughput

0.445

High

482867

RL35A
Large ribosomal subunit protein uL29A

1

1

High-throughput

0.445

High

549394

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.445

High

564285

RL8A
Large ribosomal subunit protein eL8A

1

3

High-throughput

0.445

High

355475

H2B1
Histone H2B.1

1

1

High-throughput

0.437

High

355887

H2B2
Histone H2B.2

1

1

High-throughput

0.437

High

392421

H2A2
Histone H2A.2

1

2

High-throughput

0.437

High

662161

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

663860

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

688230

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

745642

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

755286

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

755315

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.437

High

755316

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

755331

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

755335

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

755343

SGO1
Shugoshin

1

1

High-throughput

0.437

High

755345

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

357674

RL28
Large ribosomal subunit protein uL15

1

1

High-throughput

0.407

High

368034

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.407

High

406336

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.407

High

471396

RL11A
Large ribosomal subunit protein uL5A

1

2

High-throughput

0.407

High

472179

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.407

High

479106

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.407

High

481333

RL2A
Large ribosomal subunit protein uL2A

1

2

High-throughput

0.407

High

481636

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.407

High

493909

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.407

High

498919

RL4A
Large ribosomal subunit protein uL4A

1

2

High-throughput

0.407

High

511237

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

534759

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.407

High

534982

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.407

High

694654

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.407

High

732712

RL14A
Large ribosomal subunit protein eL14A

1

2

High-throughput

0.407

High

755296

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.407

High

755356

RL13A
Large ribosomal subunit protein eL13A

1

2

High-throughput

0.407

High

640939

RL5
Large ribosomal subunit protein uL18

2

0

High-throughput

0.313

High

358055

RS17A
Small ribosomal subunit protein eS17A

2

0

High-throughput

0.298

High

482253

RS18A
Small ribosomal subunit protein uS13A

2

0

High-throughput

0.298

High

706261

RS3A1
Small ribosomal subunit protein eS1A

2

0

High-throughput

0.298

High

742783

GBLP
Small ribosomal subunit protein RACK1

2

0

High-throughput

0.298

High

752440

RS20
Small ribosomal subunit protein uS10

2

0

High-throughput

0.298

High

755302

RS12
Small ribosomal subunit protein eS12

2

0

High-throughput

0.298

High

755322

PKH3
Serine/threonine-protein kinase PKH3

1

0

High-throughput

0.279

Low

755344

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.279

Low

659783

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.261

Low

755330

IMB1
Importin subunit beta-1

1

0

Small-scale

0.261

Low

755352

GIN4
Serine/threonine-protein kinase GIN4

1

0

High-throughput

0.261

Low

743256

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.253

Low

356462

H4
Histone H4

1

0

High-throughput

0.249

Low

480661

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

524293

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

705151

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.249

Low

729902

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

755292

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.249

Low

755313

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

755317

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

755338

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

404836

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.232

Low

405994

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.232

Low

470741

RS21A
Small ribosomal subunit protein eS21A

1

0

High-throughput

0.232

Low

471775

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.232

Low

479468

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.232

Low

479740

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.232

Low

481913

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.232

Low

482715

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.232

Low

644885

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.232

Low

755295

RS29A
Small ribosomal subunit protein uS14A

1

0

High-throughput

0.232

Low

755303

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.232

Low

755305

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.232

Low

755319

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.232

Low

755357

RS28A
Small ribosomal subunit protein eS28A

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024