Protein: TCPZ
T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta)

Gene: TCPZ, CCT6
Organism: Saccharomyces cerevisiae S288C
Interactions: 235
UniProt ID: P39079

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005832 - chaperonin-containing T-complex
GO:0006457 - protein folding
GO:0016887 - ATP hydrolysis activity
GO:0051082 - unfolded protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

760724

TCPG
T-complex protein 1 subunit gamma

5

19

Small-scale

0.898

High

760858

TCPD
T-complex protein 1 subunit delta

4

19

High-throughput

0.875

High

519944

TCPA
T-complex protein 1 subunit alpha

3

17

Small-scale

0.827

High

761022

TCPH
T-complex protein 1 subunit eta

2

18

High-throughput

0.789

High

760610

TCPB
T-complex protein 1 subunit beta

2

19

High-throughput

0.754

High

761015

TCPE
T-complex protein 1 subunit epsilon

2

16

High-throughput

0.754

High

628061

SIS1
Protein SIS1

3

2

High-throughput

0.633

High

761030

TCPQ
T-complex protein 1 subunit theta

1

19

High-throughput

0.618

High

761102

PLP2
Phosducin-like protein 2

2

17

High-throughput

0.611

High

594324

PP11
Serine/threonine-protein phosphatase PP1-1

3

20

High-throughput

0.609

High

761049

2ABA
Protein phosphatase PP2A regulatory subunit B

3

20

High-throughput

0.609

High

366300

HSP82
ATP-dependent molecular chaperone HSP82

2

9

High-throughput

0.584

High

543750

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.584

High

713171

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

19

High-throughput

0.575

High

491249

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.571

High

493987

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.571

High

511340

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.571

High

761012

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.571

High

454608

TBA3
Tubulin alpha-3 chain

2

20

High-throughput

0.558

High

733378

CAF4
CCR4-associated factor 4

2

20

High-throughput

0.558

High

761054

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

2

High-throughput

0.558

High

761111

WTM1
Transcriptional modulator WTM1

2

1

High-throughput

0.558

High

707090

DCA13
Protein SOF1

2

20

High-throughput

0.549

High

761074

TAP42
Type 2A phosphatase-associated protein 42

2

9

High-throughput

0.537

High

753137

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.536

High

687382

EF2
Elongation factor 2

2

5

High-throughput

0.533

High

761113

CMR1
DNA damage-binding protein CMR1

2

20

High-throughput

0.533

High

334693

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

2

2

High-throughput

0.521

High

342719

ENO1
Enolase 1

2

1

High-throughput

0.521

High

342930

ENO2
Enolase 2

2

1

High-throughput

0.521

High

402953

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

2

2

High-throughput

0.521

High

629559

CDC10
Cell division control protein 10

2

7

High-throughput

0.521

High

761039

HOS2
Probable histone deacetylase HOS2

2

20

High-throughput

0.521

High

412465

KIN28
Serine/threonine-protein kinase KIN28

1

17

High-throughput

0.501

High

419886

SNF1
Carbon catabolite-derepressing protein kinase

1

2

High-throughput

0.501

High

439656

SPS1
Sporulation-specific protein 1

1

20

High-throughput

0.501

High

614653

KC11
Casein kinase I homolog 1

1

5

High-throughput

0.501

High

743876

AKL1
Serine/threonine-protein kinase AKL1

1

9

High-throughput

0.501

High

752117

KSP1
Serine/threonine-protein kinase KSP1

1

13

High-throughput

0.501

High

761038

SCY1
Protein kinase-like protein SCY1

1

5

High-throughput

0.501

High

761063

PKH3
Serine/threonine-protein kinase PKH3

1

20

High-throughput

0.501

High

761070

CTK1
CTD kinase subunit alpha

1

20

High-throughput

0.501

High

761107

YP150
Putative serine/threonine-protein kinase YPL150W

1

7

High-throughput

0.501

High

761109

PKH2
Serine/threonine-protein kinase PKH2

1

20

High-throughput

0.501

High

579424

GBB
Guanine nucleotide-binding protein subunit beta

1

20

High-throughput

0.489

High

597840

PWP1
Periodic tryptophan protein 1

1

20

High-throughput

0.489

High

640843

CDC20
APC/C activator protein CDC20

1

20

High-throughput

0.489

High

744619

TAF5
Transcription initiation factor TFIID subunit 5

1

20

High-throughput

0.489

High

761004

PEX7
Peroxisomal targeting signal 2 receptor

1

20

High-throughput

0.489

High

761006

FHP
Flavohemoprotein

1

8

High-throughput

0.489

High

761009

UTP7
U3 small nucleolar RNA-associated protein 7

1

20

High-throughput

0.489

High

761020

COPB2
Coatomer subunit beta'

1

17

High-throughput

0.489

High

761021

PFS2
Polyadenylation factor subunit 2

1

20

High-throughput

0.489

High

761043

BRE5
UBP3-associated protein BRE5

1

5

High-throughput

0.489

High

761066

WDR59
Maintenance of telomere capping protein 5

1

20

High-throughput

0.489

High

761076

ERB1
Ribosome biogenesis protein ERB1

1

20

High-throughput

0.489

High

761103

RAD28
Radiation-sensitive protein 28

1

20

High-throughput

0.489

High

761108

WTM2
Transcriptional modulator WTM2

1

1

High-throughput

0.489

High

761112

PRP46
Pre-mRNA-splicing factor PRP46

1

20

High-throughput

0.489

High

556058

VATB
V-type proton ATPase subunit B

1

8

High-throughput

0.479

High

566586

VATA
V-type proton ATPase catalytic subunit A

1

11

High-throughput

0.479

High

694713

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.479

High

713224

TSA1
Peroxiredoxin TSA1

1

7

High-throughput

0.479

High

761047

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

761048

ACT
Actin

1

20

High-throughput

0.479

High

761071

PLP1
Phosducin-like protein 1

1

16

High-throughput

0.479

High

761110

GIN4
Serine/threonine-protein kinase GIN4

1

7

High-throughput

0.479

High

340679

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

606010

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

731574

EAP1
Protein EAP1

1

0

High-throughput

0.458

High

761033

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

761069

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

761073

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

761075

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

761056

UBC7
Ubiquitin-conjugating enzyme E2 7

1

4

High-throughput

0.457

High

693019

RPD3
Histone deacetylase RPD3

1

20

Small-scale

0.457

High

342018

ATPB
ATP synthase subunit beta, mitochondrial

1

8

High-throughput

0.445

High

539469

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

4

High-throughput

0.445

High

628829

RAD57
DNA repair protein RAD57

1

3

High-throughput

0.445

High

629278

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

7

High-throughput

0.445

High

761035

CTF18
Chromosome transmission fidelity protein 18

1

5

High-throughput

0.445

High

761037

UBC11
Ubiquitin-conjugating enzyme E2-18 kDa

1

2

High-throughput

0.445

High

761053

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

17

High-throughput

0.445

High

761058

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

1

High-throughput

0.445

High

761084

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.445

High

141336

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.437

High

375395

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

4

High-throughput

0.437

High

399472

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.437

High

454329

TBA1
Tubulin alpha-1 chain

1

20

High-throughput

0.437

High

541878

NSP1
Nucleoporin NSP1

1

2

High-throughput

0.437

High

595027

NUP1
Nucleoporin NUP1

1

4

High-throughput

0.437

High

606650

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.437

High

618774

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

20

High-throughput

0.437

High

634607

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

690204

CDC3
Cell division control protein 3

1

1

High-throughput

0.437

High

690535

CDC12
Cell division control protein 12

1

1

High-throughput

0.437

High

691628

NUP2
Nucleoporin NUP2

1

2

High-throughput

0.437

High

700066

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

2

High-throughput

0.437

High

728245

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.437

High

730803

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

744821

GLU2A
Glucosidase 2 subunit alpha

1

4

High-throughput

0.437

High

745544

MAP2
Methionine aminopeptidase 2

1

4

High-throughput

0.437

High

752349

ARP1
Centractin

1

20

High-throughput

0.437

High

753807

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.437

High

755770

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

20

Small-scale

0.437

High

758530

SEC31
Protein transport protein SEC31

1

20

High-throughput

0.437

High

761014

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

20

High-throughput

0.437

High

761026

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

7

High-throughput

0.437

High

761029

MDV1
Mitochondrial division protein 1

1

20

High-throughput

0.437

High

761062

TOM1
E3 ubiquitin-protein ligase TOM1

1

11

High-throughput

0.437

High

761077

YMW4
Uncharacterized protein YMR074C

1

5

High-throughput

0.437

High

761094

SHS1
Seventh homolog of septin 1

1

9

High-throughput

0.437

High

761101

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

593640

DBP4
ATP-dependent RNA helicase HCA4

1

0

High-throughput

0.426

High

608697

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.426

High

667518

PAP
Poly(A) polymerase

1

0

High-throughput

0.426

High

696210

STH1
Nuclear protein STH1/NPS1

1

0

High-throughput

0.426

High

705185

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

761046

NSG2
Protein NSG2

1

0

High-throughput

0.426

High

761052

ARG56
Protein ARG5,6, mitochondrial [Cleaved into: N-acetyl-gamma-glutamyl-phosphate reductase

1

0

High-throughput

0.426

High

368069

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.407

High

392123

H2A1
Histone H2A.1

1

1

High-throughput

0.407

High

419658

RAD7
DNA repair protein RAD7

1

2

High-throughput

0.407

High

423019

TOM70
Mitochondrial import receptor subunit TOM70

1

10

High-throughput

0.407

High

634142

SRO9
RNA-binding protein SRO9

1

6

High-throughput

0.407

High

688119

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

20

High-throughput

0.407

High

690078

APE2
Aminopeptidase 2, mitochondrial

1

2

High-throughput

0.407

High

693302

RPN2
26S proteasome regulatory subunit RPN2

1

2

High-throughput

0.407

High

761010

TSC11
Target of rapamycin complex 2 subunit TSC11

1

4

High-throughput

0.407

High

761011

MGDP1
Putative magnesium-dependent phosphatase YER134C

1

1

High-throughput

0.407

High

761016

TM108
Protein TMA108

1

2

High-throughput

0.407

High

761036

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

3

High-throughput

0.407

High

761042

DUS2
tRNA-dihydrouridine(20) synthase [NAD(P)+]

1

2

High-throughput

0.407

High

761045

TDA7
Topoisomerase I damage affected protein 7

1

5

High-throughput

0.407

High

761060

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.407

High

761061

GDE1
Glycerophosphocholine phosphodiesterase GDE1

1

5

High-throughput

0.407

High

761065

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

1

High-throughput

0.407

High

761078

RCO1
Transcriptional regulatory protein RCO1

1

4

High-throughput

0.407

High

761081

UTP13
U3 small nucleolar RNA-associated protein 13

1

20

High-throughput

0.407

High

761082

DUS4
tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]

1

2

High-throughput

0.407

High

761090

SSK1
Osmolarity two-component system protein SSK1

1

1

High-throughput

0.407

High

761091

BDF2
Bromodomain-containing factor 2

1

6

High-throughput

0.407

High

761104

YTM1
Ribosome biogenesis protein YTM1

1

20

High-throughput

0.407

High

761105

HOSM
Homocitrate synthase, mitochondrial

1

2

High-throughput

0.407

High

761115

HUB1
Ubiquitin-like modifier HUB1

1

1

High-throughput

0.407

High

761013

VID27
Vacuolar import and degradation protein 27

3

0

High-throughput

0.342

High

761031

HGH1
Protein HGH1

3

0

Small-scale

0.342

High

761028

STU2
Protein STU2

2

0

High-throughput

0.319

High

680033

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

2

0

High-throughput

0.313

High

407056

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.305

High

756919

RPN10
26S proteasome regulatory subunit RPN10

2

0

High-throughput

0.298

High

730978

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.279

Low

757417

SPT8
Transcription factor SPT8

1

0

High-throughput

0.279

Low

404587

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

407922

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

480676

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

481026

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.249

Low

524305

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

534992

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

599256

REB1
DNA-binding protein REB1

1

0

High-throughput

0.249

Low

631884

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

662245

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

677092

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.249

Low

688247

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

700897

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

706276

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

716242

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

753101

GRE3
NADPH-dependent aldose reductase GRE3

1

0

High-throughput

0.249

Low

761005

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

761017

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

761019

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

761023

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

761027

MHP1
MAP-homologous protein 1

1

0

High-throughput

0.249

Low

761032

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

761040

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.249

Low

761050

REG1
Resistance to glucose repression protein 1

1

0

High-throughput

0.249

Low

761064

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

761068

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

761085

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

761092

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

761098

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

141663

YA11B
Truncated transposon Ty1-A Gag-Pol polyprotein

1

0

High-throughput

0.232

Low

341798

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.232

Low

406532

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.232

Low

411001

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.232

Low

516300

RAP1
DNA-binding protein RAP1

1

0

High-throughput

0.232

Low

541711

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low

563958

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.232

Low

605431

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

615361

GYS1
Glycogen [starch] synthase isoform 1

1

0

High-throughput

0.232

Low

628756

RNA14
mRNA 3'-end-processing protein RNA14

1

0

High-throughput

0.232

Low

629623

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.232

Low

669866

MPI
Mannose-6-phosphate isomerase

1

0

High-throughput

0.232

Low

676055

XPO1
Exportin-1

1

0

High-throughput

0.232

Low

693541

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.232

Low

701327

SPT4
Transcription elongation factor SPT4

1

0

High-throughput

0.232

Low

731917

ELF1
Transcription elongation factor 1

1

0

High-throughput

0.232

Low

732142

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.232

Low

746634

RKM3
Ribosomal lysine N-methyltransferase 3

1

0

High-throughput

0.232

Low

746829

TRM7
tRNA

1

0

High-throughput

0.232

Low

747150

RXT2
Transcriptional regulatory protein RXT2

1

0

High-throughput

0.232

Low

748586

DPH7
Diphthine methyltransferase

1

0

High-throughput

0.232

Low

754081

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.232

Low

755607

DNPEP
Aspartyl aminopeptidase 4

1

0

High-throughput

0.232

Low

757270

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

761007

DPO5
rDNA transcriptional regulator POL5

1

0

High-throughput

0.232

Low

761008

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

0

High-throughput

0.232

Low

761018

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.232

Low

761024

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

0

High-throughput

0.232

Low

761025

BLM10
Proteasome activator BLM10

1

0

High-throughput

0.232

Low

761034

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.232

Low

761041

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.232

Low

761044

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.232

Low

761051

STP1
Transcription factor STP1

1

0

High-throughput

0.232

Low

761055

NOP3
Serine/arginine

1

0

High-throughput

0.232

Low

761057

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.232

Low

761059

CWC27
Peptidyl-prolyl isomerase CWC27

1

0

High-throughput

0.232

Low

761067

VPS61
Putative uncharacterized protein VPS61

1

0

High-throughput

0.232

Low

761072

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.232

Low

761079

YM91
Putative methyltransferase YMR310C

1

0

High-throughput

0.232

Low

761080

ERP1
Protein ERP1

1

0

High-throughput

0.232

Low

761083

IMB1
Importin subunit beta-1

1

0

High-throughput

0.232

Low

761086

NOC4
Nucleolar complex protein 4

1

0

High-throughput

0.232

Low

761087

SWC7
SWR1-complex protein 7

1

0

High-throughput

0.232

Low

761088

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.232

Low

761089

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.232

Low

761093

ACK1
Activator of C kinase protein 1

1

0

High-throughput

0.232

Low

761095

YL032
KH domain-containing protein YLL032C

1

0

High-throughput

0.232

Low

761096

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.232

Low

761097

RRP44
Exosome complex exonuclease DIS3

1

0

High-throughput

0.232

Low

761099

PUS7
Multisubstrate pseudouridine synthase 7

1

0

High-throughput

0.232

Low

761100

RDL2
Thiosulfate sulfurtransferase RDL2, mitochondrial

1

0

High-throughput

0.232

Low

761106

NMD4
Nonsense-mediated decay protein 4

1

0

High-throughput

0.232

Low

761114

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low

761116

SAS5
Something about silencing protein 5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024