Protein: RFC4
Replication factor C subunit 4 (Replication factor C4) (Activator 1 37 kDa subunit)

Gene: RFC4
Organism: Saccharomyces cerevisiae S288C
Interactions: 109
UniProt ID: P40339

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

772256

CTF18
Chromosome transmission fidelity protein 18

8

19

Small-scale

0.966

High

772247

RFC2
Replication factor C subunit 2

8

15

Small-scale

0.960

High

751267

RFC3
Replication factor C subunit 3

5

15

Small-scale

0.931

High

550553

PCNA
Proliferating cell nuclear antigen

4

17

Small-scale

0.896

High

747109

RFC5
Replication factor C subunit 5

3

17

High-throughput

0.855

High

751310

RFC1
Replication factor C subunit 1

3

20

High-throughput

0.855

High

772275

ELG1
Telomere length regulation protein ELG1

10

19

Small-scale

0.755

High

697296

RAD24
Checkpoint protein RAD24

6

20

Small-scale

0.727

High

680758

HS104
Heat shock protein 104

1

3

High-throughput

0.691

High

703806

PRS6B
26S proteasome regulatory subunit 6B homolog

1

2

High-throughput

0.691

High

636644

CDC48
Cell division control protein 48

1

3

High-throughput

0.646

High

744524

DPOA2
DNA polymerase alpha subunit B

2

3

High-throughput

0.621

High

756642

CTF8
Chromosome transmission fidelity protein 8

2

3

Small-scale

0.621

High

705247

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.618

High

772266

RUVB1
RuvB-like protein 1

1

11

High-throughput

0.618

High

772279

RUVB2
RuvB-like protein 2

1

11

High-throughput

0.618

High

772265

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.613

High

392453

H2A2
Histone H2A.2

2

8

High-throughput

0.611

High

423463

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

1

High-throughput

0.536

High

630416

RNQ1
[PIN+] prion protein RNQ1

1

1

High-throughput

0.536

High

676107

XPO1
Exportin-1

1

10

High-throughput

0.536

High

772252

ECO1
N-acetyltransferase ECO1

1

4

Small-scale

0.515

High

584169

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.513

High

608468

SAN1
Protein SAN1

1

0

High-throughput

0.513

High

752913

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.513

High

772253

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

772274

DDC1
DNA damage checkpoint protein 1

1

0

High-throughput

0.513

High

772278

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.513

High

745687

NU170
Nucleoporin NUP170

1

4

High-throughput

0.504

High

747174

MMS4
Crossover junction endonuclease MMS4

1

1

Small-scale

0.501

High

772267

MUS81
Crossover junction endonuclease MUS81

1

1

Small-scale

0.501

High

342034

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.500

High

366383

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.500

High

423858

ATPA
ATP synthase subunit alpha, mitochondrial

1

7

High-throughput

0.500

High

560676

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.500

High

562395

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.500

High

693313

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.500

High

772254

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.500

High

772260

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

High-throughput

0.500

High

772261

ACT
Actin

1

1

High-throughput

0.500

High

378355

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.479

High

570701

HXKG
Glucokinase-1

1

0

High-throughput

0.479

High

588103

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.479

High

141368

RS9A
Small ribosomal subunit protein uS4A

1

4

High-throughput

0.479

High

355503

H2B1
Histone H2B.1

1

16

High-throughput

0.479

High

355907

H2B2
Histone H2B.2

1

16

High-throughput

0.479

High

356512

H4
Histone H4

1

8

High-throughput

0.479

High

358098

RS17A
Small ribosomal subunit protein eS17A

1

4

High-throughput

0.479

High

383183

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.479

High

389645

DNLI1
DNA ligase 1

1

4

Small-scale

0.479

High

405659

RL26A
Large ribosomal subunit protein uL24A

1

8

High-throughput

0.479

High

407091

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.479

High

407952

RS13
Small ribosomal subunit protein uS15

1

4

High-throughput

0.479

High

413541

RS14A
Small ribosomal subunit protein uS11A

1

4

High-throughput

0.479

High

425988

RS19A
Small ribosomal subunit protein eS19A

1

5

High-throughput

0.479

High

457032

SWI6
Regulatory protein SWI6

1

2

High-throughput

0.479

High

471090

RS22A
Small ribosomal subunit protein uS8A

1

4

High-throughput

0.479

High

472226

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.479

High

480138

RS6A
Small ribosomal subunit protein eS6A

1

6

High-throughput

0.479

High

480704

RS8A
Small ribosomal subunit protein eS8A

1

6

High-throughput

0.479

High

543847

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

558088

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.479

High

631916

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.479

High

634056

DCC1
Sister chromatid cohesion protein DCC1

1

8

High-throughput

0.479

High

645480

RS7A
Small ribosomal subunit protein eS7A

1

4

High-throughput

0.479

High

662391

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

688269

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

4

High-throughput

0.479

High

689887

ASF1
Histone chaperone ASF1

1

4

Small-scale

0.479

High

698828

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

4

High-throughput

0.479

High

700450

RSSA1
Small ribosomal subunit protein uS2A

1

6

High-throughput

0.479

High

706308

RS3A1
Small ribosomal subunit protein eS1A

1

4

High-throughput

0.479

High

729946

RS27A
Small ribosomal subunit protein eS27A

1

3

High-throughput

0.479

High

752489

RS20
Small ribosomal subunit protein uS10

1

4

High-throughput

0.479

High

762260

LAA1
AP-1 accessory protein LAA1

1

4

High-throughput

0.479

High

772249

ULP2
Ubiquitin-like-specific protease 2

1

4

High-throughput

0.479

High

772250

DSN1
Kinetochore-associated protein DSN1

1

4

High-throughput

0.479

High

772255

RS12
Small ribosomal subunit protein eS12

1

4

High-throughput

0.479

High

772259

RL26B
Large ribosomal subunit protein uL24B

1

8

High-throughput

0.479

High

772262

H3
Histone H3

1

14

High-throughput

0.479

High

772263

CTF4
DNA polymerase alpha-binding protein

1

5

Small-scale

0.479

High

772264

RS15
Small ribosomal subunit protein uS19

1

4

High-throughput

0.479

High

772268

SIZ1
E3 SUMO-protein ligase SIZ1

1

4

High-throughput

0.479

High

772269

HRQ1
ATP-dependent helicase HRQ1

1

7

Small-scale

0.479

High

772270

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.479

High

772272

SGO1
Shugoshin

1

4

High-throughput

0.479

High

772273

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.479

High

772276

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.479

High

772277

SCC1
Sister chromatid cohesion protein 1

1

4

High-throughput

0.479

High

625819

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

631669

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.458

High

667590

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

733441

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

744284

TBS1
Uncharacterized transcriptional regulatory protein TBS1

1

0

High-throughput

0.458

High

772248

SPO22
Sporulation-specific protein 22

1

0

Small-scale

0.458

High

628985

SCJ1
DnaJ-related protein SCJ1

1

2

High-throughput

0.457

High

368115

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

424550

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

454350

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.445

High

556085

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.445

High

768576

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

743553

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

772271

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.437

High

612239

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

360901

TBB
Tubulin beta chain

1

1

High-throughput

0.407

High

772257

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

2

High-throughput

0.407

High

333978

ADH2
Alcohol dehydrogenase 2

1

0

High-throughput

0.279

Low

772258

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.279

Low

453002

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

772251

BNI1
Protein BNI1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024