Protein: TAF1
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (TAFII-130) (TAFII-145) (TBP-associated factor 1) (TBP-associated factor 145 kDa)

Gene: TAF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 162
UniProt ID: P46677

Gene Ontology (top 5):
GO:0001091 - RNA polymerase II general transcription initiation factor binding
GO:0003682 - chromatin binding
GO:0004402 - histone acetyltransferase activity
GO:0005634 - nucleus
GO:0005669 - transcription factor TFIID complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

527022

TBP
TATA-box-binding protein

32

8

Small-scale

0.993

High

805240

TAF7
Transcription initiation factor TFIID subunit 7

12

3

Small-scale

0.971

High

805199

TAF1
Transcription initiation factor TFIID subunit 1

3

2

Small-scale

0.817

High

805214

TAF6
Transcription initiation factor TFIID subunit 6

20

3

Small-scale

0.765

High

805233

TAF12
Transcription initiation factor TFIID subunit 12

18

5

Small-scale

0.763

High

744640

TAF5
Transcription initiation factor TFIID subunit 5

18

6

Small-scale

0.763

High

805242

TAF9
Transcription initiation factor TFIID subunit 9

16

3

Small-scale

0.761

High

805211

TAF4
Transcription initiation factor TFIID subunit 4

15

4

Small-scale

0.760

High

805251

TAF10
Transcription initiation factor TFIID subunit 10

16

3

Small-scale

0.760

High

805237

TAF11
Transcription initiation factor TFIID subunit 11

15

2

Small-scale

0.758

High

613859

TAF2
Transcription initiation factor TFIID subunit 2

13

3

Small-scale

0.757

High

715703

TAF14
Transcription initiation factor TFIID subunit 14

13

1

Small-scale

0.754

High

515114

TAF13
Transcription initiation factor TFIID subunit 13

12

2

Small-scale

0.752

High

805255

TAF3
Transcription initiation factor TFIID subunit 3

16

0

Small-scale

0.728

High

805232

TAF8
Transcription initiation factor TFIID subunit 8

11

0

Small-scale

0.720

High

805226

ADA2
Transcriptional adapter 2

4

2

Small-scale

0.694

High

356557

H4
Histone H4

3

2

High-throughput

0.650

High

805256

RUVB2
RuvB-like protein 2

3

1

High-throughput

0.634

High

728715

BDF1
Bromodomain-containing factor 1

2

13

Small-scale

0.612

High

423687

ADR1
Regulatory protein ADR1

2

1

Small-scale

0.611

High

599264

REB1
DNA-binding protein REB1

2

0

High-throughput

0.595

High

599480

VPS1
Vacuolar protein sorting-associated protein 1

2

0

High-throughput

0.595

High

686852

MED16
Mediator of RNA polymerase II transcription subunit 16

2

0

High-throughput

0.595

High

410007

NOT3
General negative regulator of transcription subunit 3

2

1

Small-scale

0.586

High

805258

NOT5
General negative regulator of transcription subunit 5

2

1

Small-scale

0.586

High

407145

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.585

High

355531

H2B1
Histone H2B.1

2

1

High-throughput

0.571

High

355928

H2B2
Histone H2B.2

2

1

High-throughput

0.571

High

744880

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

2

3

High-throughput

0.571

High

805220

H3
Histone H3

2

4

High-throughput

0.571

High

636153

NOT1
General negative regulator of transcription subunit 1

1

0

Small-scale

0.568

High

446180

MYO1
Myosin-1

2

1

High-throughput

0.567

High

655674

FUN19
SWIRM domain-containing protein FUN19

2

0

High-throughput

0.563

High

805227

TBF1
Protein TBF1

2

0

High-throughput

0.563

High

805238

PUF6
Pumilio homology domain family member 6

2

0

High-throughput

0.563

High

757434

SPT8
Transcription factor SPT8

2

0

Small-scale

0.560

High

662592

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.559

High

805235

HMO1
High mobility group protein 1

1

2

Small-scale

0.552

High

516306

RAP1
DNA-binding protein RAP1

2

0

Small-scale

0.547

High

805229

GCN5
Histone acetyltransferase GCN5

1

7

High-throughput

0.536

High

511784

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

805200

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.513

High

420611

SPT3
Protein SPT3

1

2

Small-scale

0.501

High

536237

DPOZ
DNA polymerase zeta catalytic subunit

1

0

High-throughput

0.493

High

755831

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

514193

NHP6A
Non-histone chromosomal protein 6A

1

2

Small-scale

0.481

High

514261

NHP6B
Non-histone chromosomal protein 6B

1

2

Small-scale

0.481

High

706026

NIP80
Protein NIP100

1

2

High-throughput

0.481

High

772478

RAD26
DNA repair and recombination protein RAD26

1

4

High-throughput

0.481

High

805222

CTR9
RNA polymerase-associated protein CTR9

1

1

High-throughput

0.481

High

805247

IMH1
Golgin IMH1

1

3

High-throughput

0.481

High

645763

INO2
Protein INO2

1

0

Small-scale

0.480

High

805209

RFX1
RFX-like DNA-binding protein RFX1

1

0

Small-scale

0.480

High

805212

SPT20
Transcription factor SPT20

1

0

Small-scale

0.480

High

472263

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

543973

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

689903

ASF1
Histone chaperone ASF1

1

1

Small-scale

0.479

High

805216

INO80
Chromatin-remodeling ATPase INO80

1

4

High-throughput

0.479

High

805218

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

560714

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.460

High

633870

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.460

High

659804

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.460

High

690224

CDC3
Cell division control protein 3

1

0

High-throughput

0.460

High

704212

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

0

Small-scale

0.460

High

710779

CASP
Protein CASP

1

0

High-throughput

0.460

High

762330

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.460

High

772293

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.460

High

778809

NOP2
25S rRNA

1

0

High-throughput

0.460

High

805202

YJ41B
Transposon Ty4-J Gag-Pol polyprotein

1

0

High-throughput

0.460

High

805205

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.460

High

805244

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.460

High

805252

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.460

High

805257

SKS1
Serine/threonine-protein kinase SKS1

1

0

High-throughput

0.460

High

141402

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

358135

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

368746

GCN4
General control transcription factor GCN4

1

0

Small-scale

0.458

High

383219

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

405693

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

413585

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

426021

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

471129

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

480176

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

480747

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

482325

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

558124

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

631953

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

688306

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

706349

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

716282

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

729981

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

752528

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

805207

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.458

High

805217

SGF73
SAGA-associated factor 73

1

0

High-throughput

0.458

High

805224

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

805236

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

805253

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

491632

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494287

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

696224

STH1
Nuclear protein STH1/NPS1

1

4

High-throughput

0.445

High

697665

T2AG
Transcription initiation factor IIA subunit 2

1

1

High-throughput

0.445

High

752381

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.445

High

754244

RSC30
Chromatin structure-remodeling complex protein RSC30

1

1

High-throughput

0.445

High

797911

RSC8
Chromatin structure-remodeling complex protein RSC8

1

2

High-throughput

0.445

High

805225

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

12

High-throughput

0.445

High

805234

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.445

High

805243

ARP9
Actin-like protein ARP9

1

1

High-throughput

0.445

High

805245

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

11

High-throughput

0.445

High

805246

RSC3
Chromatin structure-remodeling complex protein RSC3

1

1

High-throughput

0.445

High

805248

BDF2
Bromodomain-containing factor 2

1

10

High-throughput

0.445

High

805250

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

4

High-throughput

0.445

High

805259

H2AZ
Histone H2A.Z

1

1

High-throughput

0.445

High

805254

RUD3
GRIP domain-containing protein RUD3

1

2

High-throughput

0.439

High

376830

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.426

High

392483

H2A2
Histone H2A.2

1

0

High-throughput

0.426

High

404625

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.426

High

419354

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

424581

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

498981

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.426

High

501174

HSF
Heat shock transcription factor

1

0

High-throughput

0.426

High

534788

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.426

High

605077

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.426

High

622170

MCM3
DNA replication licensing factor MCM3

1

0

High-throughput

0.426

High

635518

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.426

High

640987

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

698668

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

0

High-throughput

0.426

High

700489

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.426

High

707027

MSN4
Zinc finger protein MSN4

1

0

High-throughput

0.426

High

805215

MCM6
DNA replication licensing factor MCM6

1

0

High-throughput

0.426

High

805219

ACT
Actin

1

0

High-throughput

0.426

High

805223

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

399523

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

805210

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.407

High

805241

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.407

High

549427

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

0

High-throughput

0.307

High

731640

MNN4
Protein MNN4

2

0

High-throughput

0.307

High

805230

CLU
Clustered mitochondria protein 1

2

0

High-throughput

0.307

High

145913

YO304
Uncharacterized protein YOR304C-A

1

0

High-throughput

0.251

Low

404072

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.251

Low

409907

CDC37
Hsp90 co-chaperone Cdc37

1

0

Small-scale

0.251

Low

677097

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.251

Low

680287

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.251

Low

728424

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

731826

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.251

Low

741421

PAM1
Protein PAM1

1

0

High-throughput

0.251

Low

747586

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.251

Low

758074

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.251

Low

768140

VFA1
VPS4-associated protein 1

1

0

High-throughput

0.251

Low

805201

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.251

Low

805204

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

805206

ACF4
Assembly-complementing factor 4

1

0

High-throughput

0.251

Low

805208

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.251

Low

805213

PSP1
Protein PSP1

1

0

High-throughput

0.251

Low

805221

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

805231

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.251

Low

805239

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

805249

YET3
Endoplasmic reticulum transmembrane protein 3

1

0

High-throughput

0.251

Low

747618

SHE3
SWI5-dependent HO expression protein 3

1

0

High-throughput

0.249

Low

797746

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.249

Low

705343

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

805203

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low

805228

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024