Protein: PESC
Pescadillo homolog (Nucleolar protein 7) (Ribosomal RNA-processing protein 13)

Gene: PESC, NOP7
Organism: Saccharomyces cerevisiae S288C
Interactions: 234
UniProt ID: P53261

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

860879

ERB1
Ribosome biogenesis protein ERB1

20

4

Small-scale

0.989

High

860841

PESC
Pescadillo homolog

6

1

Small-scale

0.932

High

860909

YTM1
Ribosome biogenesis protein YTM1

19

4

Small-scale

0.764

High

860866

NOG1
Nucleolar GTP-binding protein 1

19

5

Small-scale

0.764

High

860870

HAS1
ATP-dependent RNA helicase HAS1

16

6

Small-scale

0.762

High

860846

NOG2
Nucleolar GTP-binding protein 2

16

1

Small-scale

0.760

High

766670

NUG1
Nuclear GTP-binding protein NUG1

12

1

Small-scale

0.756

High

754883

SSF1
Ribosome biogenesis protein SSF1

13

1

Small-scale

0.755

High

564335

RL8A
Large ribosomal subunit protein eL8A

2

2

Small-scale

0.754

High

667239

RL8B
Large ribosomal subunit protein eL8B

2

2

Small-scale

0.754

High

776468

RLP7
Ribosome biogenesis protein RLP7

11

2

Small-scale

0.754

High

859487

NSA1
Ribosome biogenesis protein NSA1

11

1

Small-scale

0.754

High

860896

RLP24
Ribosome biogenesis protein RLP24

11

1

Small-scale

0.753

High

860853

NOP15
Ribosome biogenesis protein 15

9

1

Small-scale

0.751

High

860913

MAK21
Ribosome biogenesis protein MAK21

9

3

Small-scale

0.749

High

764208

NOC2
Nucleolar complex protein 2

9

1

Small-scale

0.747

High

731838

EBP2
rRNA-processing protein EBP2

9

1

Small-scale

0.747

High

860915

DBP10
ATP-dependent RNA helicase DBP10

8

3

Small-scale

0.747

High

703083

MRT4
Ribosome assembly factor MRT4

9

2

Small-scale

0.745

High

778824

NOP2
25S rRNA

8

2

Small-scale

0.744

High

860908

MDN1
Midasin

7

1

Small-scale

0.739

High

638820

SPB4
ATP-dependent rRNA helicase SPB4

7

5

Small-scale

0.736

High

860910

NOP53
Ribosome biogenesis protein NOP53

7

1

Small-scale

0.736

High

634428

SPB1
27S pre-rRNA

6

1

Small-scale

0.730

High

860899

BRX1
Ribosome biogenesis protein BRX1

6

5

Small-scale

0.730

High

733883

RPF2
Ribosome biogenesis protein RPF2

16

0

Small-scale

0.730

High

742037

NOP4
Nucleolar protein 4

6

1

Small-scale

0.729

High

860872

ARX1
Probable metalloprotease ARX1

15

0

Small-scale

0.727

High

754151

CIC1
Proteasome-interacting protein CIC1

13

0

Small-scale

0.726

High

860918

IF6
Eukaryotic translation initiation factor 6

12

0

Small-scale

0.726

High

756847

RIX1
Pre-rRNA-processing protein RIX1

13

0

Small-scale

0.725

High

860897

BUD20
Bud site selection protein 20

11

0

Small-scale

0.724

High

630878

NLE1
Ribosome assembly protein 4

6

1

Small-scale

0.721

High

768025

NSA2
Ribosome biogenesis protein NSA2

11

0

Small-scale

0.721

High

860842

SDA1
Protein SDA1

10

0

Small-scale

0.718

High

535063

RL3
Large ribosomal subunit protein uL3

10

0

Small-scale

0.718

High

641016

RL5
Large ribosomal subunit protein uL18

9

0

Small-scale

0.715

High

699706

DRS1
ATP-dependent RNA helicase DRS1

5

5

Small-scale

0.714

High

715465

RRP1
Ribosomal RNA-processing protein 1

5

1

Small-scale

0.714

High

860882

RRP5
rRNA biogenesis protein RRP5

7

0

High-throughput

0.713

High

860907

NIP7
60S ribosome subunit biogenesis protein NIP7

6

0

Small-scale

0.695

High

383262

RL25
Large ribosomal subunit protein uL23

6

0

Small-scale

0.688

High

594059

MAK11
Protein MAK11

4

2

Small-scale

0.686

High

860895

NOC3
Nucleolar complex-associated protein 3

4

2

Small-scale

0.686

High

755309

RPF1
Ribosome production factor 1

5

0

Small-scale

0.679

High

766581

NOP16
Nucleolar protein 16

5

0

Small-scale

0.678

High

399569

RLA0
Large ribosomal subunit protein uL10

4

2

Small-scale

0.676

High

499011

RL4A
Large ribosomal subunit protein uL4A

4

1

Small-scale

0.672

High

691395

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

2

High-throughput

0.665

High

797372

LOC1
60S ribosomal subunit assembly/export protein LOC1

4

0

Small-scale

0.664

High

549443

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

1

Small-scale

0.662

High

860865

IMA1
Importin subunit alpha

3

1

High-throughput

0.662

High

501233

MAK16
Protein MAK16

4

0

Small-scale

0.657

High

534811

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.656

High

860901

DNLI4
DNA ligase 4

1

0

High-throughput

0.656

High

860905

RRS1
Regulator of ribosome biosynthesis

3

1

High-throughput

0.650

High

732232

RRP14
Ribosomal RNA-processing protein 14

4

0

High-throughput

0.648

High

860874

RRP17
Ribosomal RNA-processing protein 17

4

0

High-throughput

0.648

High

860849

IPI3
Pre-rRNA-processing protein IPI3

3

2

High-throughput

0.640

High

860850

NOP13
Nucleolar protein 13

3

0

High-throughput

0.638

High

405235

RL17A
Large ribosomal subunit protein uL22A

3

1

Small-scale

0.633

High

584769

CSK22
Casein kinase II subunit alpha'

2

3

High-throughput

0.628

High

810577

ALB1
Ribosome biogenesis protein ALB1

3

0

Small-scale

0.628

High

860891

RRP15
Ribosomal RNA-processing protein 15

3

0

High-throughput

0.628

High

860856

ORC1
Origin recognition complex subunit 1

2

1

Small-scale

0.624

High

481382

RL2A
Large ribosomal subunit protein uL2A

3

0

Small-scale

0.613

High

859975

CGR1
rRNA-processing protein CGR1

3

0

Small-scale

0.606

High

860878

PUF6
Pumilio homology domain family member 6

3

0

Small-scale

0.606

High

696376

PP12
Serine/threonine-protein phosphatase PP1-2

2

0

High-throughput

0.602

High

744218

MAK5
ATP-dependent RNA helicase MAK5

2

6

High-throughput

0.601

High

860886

IMB1
Importin subunit beta-1

2

0

High-throughput

0.585

High

481194

RL1A
Large ribosomal subunit protein uL1A

2

1

Small-scale

0.584

High

624138

DBP2
ATP-dependent RNA helicase DBP2

2

2

High-throughput

0.584

High

704379

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

1

High-throughput

0.584

High

742909

GBLP
Small ribosomal subunit protein RACK1

2

2

High-throughput

0.584

High

757308

FKBP3
Peptidyl-prolyl cis-trans isomerase

2

3

High-throughput

0.584

High

810268

RL17B
Large ribosomal subunit protein uL22B

2

1

Small-scale

0.584

High

810882

MTR4
ATP-dependent RNA helicase DOB1

2

2

Small-scale

0.584

High

860855

RCM1
25S rRNA

2

2

High-throughput

0.584

High

860858

H3
Histone H3

2

2

High-throughput

0.584

High

860888

FKBP4
FK506-binding protein 4

2

3

High-throughput

0.584

High

860889

JIP5
WD repeat-containing protein JIP5

2

2

High-throughput

0.584

High

860890

DBP9
ATP-dependent RNA helicase DBP9

2

3

High-throughput

0.584

High

860894

RIX7
Ribosome biogenesis ATPase RIX7

2

2

Small-scale

0.584

High

860898

NOP12
Nucleolar protein 12

2

1

High-throughput

0.584

High

860916

NOP58
Nucleolar protein 58

2

1

High-throughput

0.584

High

680884

HS104
Heat shock protein 104

2

1

High-throughput

0.571

High

746252

YBC8
UPF0642 protein YBL028C

2

0

High-throughput

0.559

High

755244

IPI1
Pre-rRNA-processing protein IPI1

2

0

High-throughput

0.559

High

792517

UTP10
U3 small nucleolar RNA-associated protein 10

2

0

High-throughput

0.559

High

512135

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

407205

RS3
Small ribosomal subunit protein uS3

2

0

Small-scale

0.547

High

408028

RS13
Small ribosomal subunit protein uS15

2

0

Small-scale

0.547

High

860861

RS15
Small ribosomal subunit protein uS19

2

0

Small-scale

0.547

High

597868

PWP1
Periodic tryptophan protein 1

1

2

High-throughput

0.541

High

698727

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.537

High

392164

H2A1
Histone H2A.1

1

1

High-throughput

0.536

High

404651

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.536

High

550085

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.536

High

744658

TAF5
Transcription initiation factor TFIID subunit 5

1

1

High-throughput

0.536

High

860860

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

860867

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

1

High-throughput

0.536

High

860869

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.536

High

860857

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.527

High

820079

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.517

High

485784

IF4A
ATP-dependent RNA helicase eIF4A

1

2

High-throughput

0.515

High

860479

YG2A
Zinc finger protein YGR067C

1

1

High-throughput

0.515

High

757951

CSK2C
Casein kinase II subunit beta'

1

0

High-throughput

0.513

High

774936

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.513

High

859787

SGF73
SAGA-associated factor 73

1

0

High-throughput

0.513

High

860847

ELOA1
Elongin-A

1

0

High-throughput

0.513

High

860893

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

376870

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.500

High

485560

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.500

High

627657

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.493

High

860877

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.493

High

860911

RTK1
Probable serine/threonine-protein kinase RTK1

1

1

High-throughput

0.489

High

860862

PVH1
Tyrosine-protein phosphatase YVH1

1

0

Small-scale

0.486

High

860864

RPM2
Ribonuclease P protein component, mitochondrial

1

0

Small-scale

0.480

High

605094

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.479

High

382777

RL24A
Large ribosomal subunit protein eL24A

1

1

Small-scale

0.479

High

406033

RL33A
Large ribosomal subunit protein eL33A

1

1

Small-scale

0.479

High

471419

RL11A
Large ribosomal subunit protein uL5A

1

1

Small-scale

0.479

High

480222

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

593548

DBP3
ATP-dependent RNA helicase DBP3

1

2

High-throughput

0.479

High

634706

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.479

High

650347

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.479

High

698174

AFG2
ATPase family gene 2 protein

1

2

High-throughput

0.479

High

744560

SWD3
COMPASS component SWD3

1

3

Small-scale

0.479

High

780490

RL33B
Large ribosomal subunit protein eL33B

1

1

Small-scale

0.479

High

829642

RL4B
Large ribosomal subunit protein uL4B

1

1

Small-scale

0.479

High

860843

YG5X
Putative methyltransferase YGR283C

1

1

High-throughput

0.479

High

860844

DBP6
ATP-dependent RNA helicase DBP6

1

5

High-throughput

0.479

High

860848

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

3

High-throughput

0.479

High

860851

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

Small-scale

0.479

High

860854

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

860868

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

860876

RRB1
Ribosome assembly protein RRB1

1

1

Small-scale

0.479

High

860880

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.479

High

860892

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

860912

SSF2
Ribosome biogenesis protein SSF2

1

1

High-throughput

0.479

High

860914

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

860917

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

860919

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

860920

RRP12
Ribosomal RNA-processing protein 12

1

1

High-throughput

0.479

High

860921

RL11B
Large ribosomal subunit protein uL5B

1

1

Small-scale

0.479

High

860922

MEX67
mRNA export factor MEX67

1

1

High-throughput

0.479

High

692992

MSS1
tRNA modification GTPase MSS1, mitochondrial

1

4

High-throughput

0.470

High

141442

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

405738

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

408419

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

413624

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

426062

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

480791

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

481051

RL23B
Large ribosomal subunit protein uL14B

1

0

Small-scale

0.458

High

482760

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.458

High

558171

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

604591

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

628303

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

635139

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

645084

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

645559

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

662866

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

664959

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

688340

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

688789

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.458

High

691093

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

706394

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

710903

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

730032

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

748666

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

752572

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

756373

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.458

High

774581

BMT5
25S rRNA

1

0

High-throughput

0.458

High

775217

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

811781

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

841411

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

859387

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.458

High

860845

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

860873

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

860875

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

860884

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.458

High

860887

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

860900

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.458

High

860902

SGO1
Shugoshin

1

0

High-throughput

0.458

High

860904

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

366641

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

479506

RS24A
Small ribosomal subunit protein eS24A

1

1

Small-scale

0.445

High

491936

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494540

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

695173

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

769025

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

472307

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

482370

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

860903

HRK1
Serine/threonine-protein kinase HRK1

1

1

High-throughput

0.437

High

357708

RL28
Large ribosomal subunit protein uL15

1

0

Small-scale

0.426

High

560746

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

631994

RS2
Small ribosomal subunit protein uS5

1

0

Small-scale

0.426

High

692576

ZUO1
Zuotin

1

0

High-throughput

0.426

High

858995

MCM6
DNA replication licensing factor MCM6

1

0

Small-scale

0.426

High

860863

NU116
Nucleoporin NUP116/NSP116

1

0

Small-scale

0.426

High

860883

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.426

High

478383

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.407

High

544142

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.407

High

705467

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

766128

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.407

High

772569

JEM1
DnaJ-like chaperone JEM1

1

3

High-throughput

0.407

High

750138

IF5
Eukaryotic translation initiation factor 5

2

0

High-throughput

0.307

High

696551

DSS4
Protein DSS4

1

0

High-throughput

0.279

Low

860859

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.279

Low

860885

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.279

Low

762797

SOP4
Protein SOP4

1

0

High-throughput

0.269

Low

860881

NTE1
Lysophospholipase NTE1

1

0

High-throughput

0.269

Low

520854

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.261

Low

358173

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

471167

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

471804

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.249

Low

500628

TIR1
Cold shock-induced protein TIR1

1

0

High-throughput

0.249

Low

629577

CDC10
Cell division control protein 10

1

0

High-throughput

0.249

Low

700534

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

754079

RRF1
Ribosome-recycling factor, mitochondrial

1

0

Small-scale

0.249

Low

762412

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

778739

CDC1
Cell division control protein 1

1

0

High-throughput

0.249

Low

860852

RN35
Large ribosomal subunit protein bL35m

1

0

Small-scale

0.249

Low

860871

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

860906

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

588169

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

629009

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low

748457

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.232

Low

784181

RL10
Large ribosomal subunit protein uL16

1

0

Small-scale

0.232

Low

810083

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

811406

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

817280

HLJ1
Protein HLJ1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024