Protein: THO2
THO complex subunit 2 (Low dye-binding protein 5) (THO complex subunit RLR1) (Zinc-regulated gene 13 protein)

Gene: THO2
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: P53552

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000445 - THO complex part of transcription export complex
GO:0000446 - nucleoplasmic THO complex
GO:0000781 - chromosome, telomeric region
GO:0003676 - nucleic acid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862759

TEX1
Protein TEX1

7

16

Small-scale

0.962

High

568895

HPR1
THO complex subunit HPR1

17

0

Small-scale

0.936

High

141751

THP2
THO complex subunit THP2

11

0

Small-scale

0.926

High

706159

MFT1
THO complex subunit MFT1

10

0

Small-scale

0.926

High

862769

SUB2
ATP-dependent RNA helicase SUB2

4

11

Small-scale

0.892

High

862757

THO2
THO complex subunit 2

2

11

Small-scale

0.776

High

633973

GBP2
Serine/arginine

6

5

Small-scale

0.732

High

757860

HRB1
Serine/arginine

4

5

Small-scale

0.691

High

862774

YRA1
RNA annealing protein YRA1

4

6

Small-scale

0.691

High

710192

NCBP1
Nuclear cap-binding protein complex subunit 1

4

2

Small-scale

0.678

High

862770

ULS1
ATP-dependent helicase ULS1

1

6

High-throughput

0.665

High

862765

IMA1
Importin subunit alpha

3

5

High-throughput

0.662

High

742917

GBLP
Small ribosomal subunit protein RACK1

1

16

High-throughput

0.618

High

862767

IMB1
Importin subunit beta-1

2

1

High-throughput

0.612

High

558178

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

2

Small-scale

0.584

High

692045

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

1

Small-scale

0.584

High

862772

NCBP2
Nuclear cap-binding protein subunit 2

2

4

Small-scale

0.584

High

494576

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

512186

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

614747

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.536

High

680893

HS104
Heat shock protein 104

1

1

High-throughput

0.536

High

389405

HXKB
Hexokinase-2

1

0

High-throughput

0.493

High

376876

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

4

Small-scale

0.479

High

407213

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

413632

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

501392

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

2

Small-scale

0.479

High

606089

RAD53
Serine/threonine-protein kinase RAD53

1

4

High-throughput

0.479

High

752580

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

862758

PAP2
Poly(A) RNA polymerase protein 2

1

2

Small-scale

0.479

High

862762

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

862763

NOP3
Serine/arginine

1

16

Small-scale

0.479

High

862766

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

862773

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

862776

SMC6
Structural maintenance of chromosomes protein 6

1

14

High-throughput

0.479

High

862777

MEX67
mRNA export factor MEX67

1

2

High-throughput

0.479

High

662904

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688348

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

805115

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.458

High

450128

HSP73
Heat shock protein SSA3

1

7

High-throughput

0.445

High

485562

SSBP1
Single-stranded nucleic acid-binding protein

1

5

High-throughput

0.445

High

491979

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

633438

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.445

High

695204

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

696029

HSP79
Heat shock protein homolog SSE2

1

9

High-throughput

0.445

High

754589

SSZ1
Ribosome-associated complex subunit SSZ1

1

6

High-throughput

0.445

High

761392

XDJ1
DnaJ protein homolog XDJ1

1

2

High-throughput

0.445

High

358182

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

405745

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

408035

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

426071

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

472315

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.437

High

480229

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

700542

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

706403

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

478397

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.407

High

541763

SEC63
Protein translocation protein SEC63

1

5

High-throughput

0.407

High

544161

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.407

High

705483

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

817282

HLJ1
Protein HLJ1

1

6

High-throughput

0.407

High

862760

JJJ1
J protein JJJ1

1

6

High-throughput

0.407

High

862768

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

3

High-throughput

0.407

High

767903

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.265

Low

141449

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

383268

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

471174

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

480796

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

482379

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

500629

TIR1
Cold shock-induced protein TIR1

1

0

High-throughput

0.249

Low

541594

CBS2
Cytochrome B translational activator protein CBS2

1

0

High-throughput

0.249

Low

632003

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

730041

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

762424

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

763604

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

0

Small-scale

0.249

Low

820086

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

862761

YNO0
Uncharacterized protein YNL140C

1

0

High-throughput

0.249

Low

862764

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

862771

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

862775

AIR2
Protein AIR2

1

0

Small-scale

0.249

Low

810089

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024