Protein: LGE1
Transcriptional regulatory protein LGE1 (Large cells protein 1)

Gene: LGE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 147
UniProt ID: Q02796

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006279 - premeiotic DNA replication
GO:0006325 - chromatin organization
GO:0008361 - regulation of cell size

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

972705

BRE1
E3 ubiquitin-protein ligase BRE1

7

0

Small-scale

0.713

High

972694

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.699

High

622073

SSD1
Protein SSD1

3

0

High-throughput

0.606

High

865840

CBK1
Serine/threonine-protein kinase CBK1

3

0

High-throughput

0.606

High

605685

KIN3
Serine/threonine-protein kinase KIN3

2

1

High-throughput

0.571

High

629349

MSH3
DNA mismatch repair protein MSH3

2

2

High-throughput

0.571

High

639285

MSH2
DNA mismatch repair protein MSH2

2

2

High-throughput

0.571

High

752187

KSP1
Serine/threonine-protein kinase KSP1

2

1

High-throughput

0.571

High

756432

SPC97
Spindle pole body component SPC97

2

1

High-throughput

0.571

High

862650

SPC98
Spindle pole body component SPC98

2

1

High-throughput

0.571

High

972696

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

2

1

High-throughput

0.571

High

972700

MSH6
DNA mismatch repair protein MSH6

2

2

High-throughput

0.571

High

356672

H4
Histone H4

2

0

High-throughput

0.547

High

419630

RAD52
DNA repair and recombination protein RAD52

2

0

High-throughput

0.547

High

630092

SNT1
Probable DNA-binding protein SNT1

2

0

High-throughput

0.547

High

650372

SPT5
Transcription elongation factor SPT5

2

0

High-throughput

0.547

High

689288

SP110
Spindle pole body component 110

2

0

High-throughput

0.547

High

705953

SPC29
Spindle pole component 29

2

0

High-throughput

0.547

High

715235

TOR1
Serine/threonine-protein kinase TOR1

2

0

High-throughput

0.547

High

732514

SPC42
Spindle pole body component SPC42

2

0

High-throughput

0.547

High

961467

CDC14
Tyrosine-protein phosphatase CDC14

2

0

High-throughput

0.547

High

761187

RGA1
Rho-type GTPase-activating protein 1

2

1

High-throughput

0.521

High

810718

NET1
Nucleolar protein NET1

2

1

High-throughput

0.521

High

968046

KIN4
Serine/threonine-protein kinase KIN4

2

1

High-throughput

0.521

High

676304

XPO1
Exportin-1

1

0

High-throughput

0.513

High

744897

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.493

High

416063

DED1
ATP-dependent RNA helicase DED1

1

2

High-throughput

0.479

High

624163

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.479

High

560774

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.460

High

703717

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

972704

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

366769

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.458

High

407262

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

420160

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

501405

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

High-throughput

0.458

High

558216

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

604604

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

663096

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688391

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

742954

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

866717

BOP3
Protein BOP3

1

0

High-throughput

0.458

High

963167

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

965472

NOP3
Serine/arginine

1

0

High-throughput

0.458

High

492198

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494770

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

624223

DBP1
ATP-dependent RNA helicase DBP1

1

2

High-throughput

0.445

High

695356

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

972702

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

548438

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

3

High-throughput

0.437

High

341832

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.426

High

392542

H2A2
Histone H2A.2

1

0

High-throughput

0.426

High

410234

UBC2
Ubiquitin-conjugating enzyme E2 2

1

0

High-throughput

0.426

High

424903

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.426

High

512434

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

540628

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

634183

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.426

High

636721

CDC48
Cell division control protein 48

1

0

High-throughput

0.426

High

690639

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.426

High

696391

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.426

High

732387

MUD2
Splicing factor MUD2

1

0

High-throughput

0.426

High

744564

SWD3
COMPASS component SWD3

1

0

High-throughput

0.426

High

747252

SIF2
SIR4-interacting protein SIF2

1

0

High-throughput

0.426

High

755797

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

High-throughput

0.426

High

757867

HRB1
Serine/arginine

1

0

High-throughput

0.426

High

774403

HOS4
Protein HOS4

1

0

High-throughput

0.426

High

793601

BRE2
COMPASS component BRE2

1

0

High-throughput

0.426

High

797134

MOB2
CBK1 kinase activator protein MOB2

1

0

High-throughput

0.426

High

809631

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.426

High

851032

ROM2
RHO1 GDP-GTP exchange protein 2

1

0

High-throughput

0.426

High

862276

TBG
Tubulin gamma chain

1

0

High-throughput

0.426

High

862733

H1
Histone H1

1

0

High-throughput

0.426

High

972695

IMA1
Importin subunit alpha

1

0

High-throughput

0.426

High

972697

SPP1
COMPASS component SPP1

1

0

High-throughput

0.426

High

972698

SDC1
COMPASS component SDC1

1

0

High-throughput

0.426

High

969458

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.407

High

756562

KOG1
Target of rapamycin complex 1 subunit KOG1

3

0

High-throughput

0.330

High

763706

MBO1
Gamma tubulin complex adapter SPC72

2

0

High-throughput

0.300

High

416807

CDC31
Cell division control protein 31

2

0

High-throughput

0.298

High

526294

KIN2
Serine/threonine-protein kinase KIN2

2

0

High-throughput

0.298

High

643028

BUB2
Mitotic check point protein BUB2

2

0

High-throughput

0.298

High

687891

NUD1
Protein NUD1

2

0

High-throughput

0.298

High

743180

BOB1
Protein BOB1

2

0

High-throughput

0.298

High

743920

AKL1
Serine/threonine-protein kinase AKL1

2

0

High-throughput

0.298

High

745397

SEA4
SEH-associated protein 4

2

0

High-throughput

0.298

High

765658

BEM2
GTPase-activating protein BEM2/IPL2

2

0

High-throughput

0.298

High

767014

FIR1
Factor interacting with REF2

2

0

High-throughput

0.298

High

774214

TAO3
Cell morphogenesis protein PAG1

2

0

High-throughput

0.298

High

837538

PSP2
Protein PSP2

2

0

High-throughput

0.298

High

865533

CNM67
Chaotic nuclear migration protein 67

2

0

High-throughput

0.298

High

972706

TCO89
Target of rapamycin complex 1 subunit TCO89

2

0

High-throughput

0.298

High

972712

YB296
Uncharacterized protein YBR296C-A

1

0

High-throughput

0.282

High

629762

STE50
Protein STE50

1

0

High-throughput

0.251

Low

688922

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

690253

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

767537

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

860678

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

861100

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.251

Low

959846

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.251

Low

972709

NYV1
Vacuolar v-SNARE NYV1

1

0

High-throughput

0.251

Low

972711

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.251

Low

141485

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

358222

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

383312

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405790

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

408079

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

413671

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

426113

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

471214

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

480271

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

480838

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

482417

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

524425

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

632046

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

644818

RFA3
Replication factor A protein 3

1

0

High-throughput

0.249

Low

645610

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

687466

EF2
Elongation factor 2

1

0

High-throughput

0.249

Low

696705

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.249

Low

697849

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.249

Low

699808

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.249

Low

700588

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

752624

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

820129

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

859413

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.249

Low

866035

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.249

Low

967714

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

972699

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.249

Low

972701

PAL1
Protein PAL1

1

0

High-throughput

0.249

Low

972703

YL352
F-box protein YLR352W

1

0

High-throughput

0.249

Low

972707

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

972708

UBX3
UBX domain-containing protein 3

1

0

Small-scale

0.249

Low

972710

YO093
Uncharacterized protein YOR093C

1

0

High-throughput

0.249

Low

336731

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.232

Low

516233

KAR1
Cell division control protein KAR1

1

0

High-throughput

0.232

Low

541914

NSP1
Nucleoporin NSP1

1

0

High-throughput

0.232

Low

585365

MYO2
Myosin-2

1

0

High-throughput

0.232

Low

627552

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.232

Low

634362

LRE1
Laminarase-resistance protein LRE1

1

0

High-throughput

0.232

Low

741348

STT4
Phosphatidylinositol 4-kinase STT4

1

0

High-throughput

0.232

Low

741429

PAM1
Protein PAM1

1

0

High-throughput

0.232

Low

747764

ICS2
Increased copper sensitivity protein 2

1

0

High-throughput

0.232

Low

756274

KEL1
Kelch repeat-containing protein 1

1

0

High-throughput

0.232

Low

760673

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

764878

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.232

Low

783345

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.232

Low

811857

BFA1
Mitotic check point protein BFA1

1

0

High-throughput

0.232

Low

817346

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024