Protein: RRP44
Exosome complex exonuclease DIS3 (EC 3.1.13.-) (EC 3.1.26.-) (Chromosome disjunction protein 3) (Ribosomal RNA-processing protein 44)

Gene: RRP44, DIS3
Organism: Saccharomyces cerevisiae S288C
Interactions: 120
UniProt ID: Q08162

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

860819

RRP46
Exosome complex component RRP46

15

16

Small-scale

0.983

High

809596

RRP41
Exosome complex component SKI6

12

20

Small-scale

0.982

High

630276

RRP43
Exosome complex component RRP43

12

1

Small-scale

0.981

High

984317

RRP45
Exosome complex component RRP45

11

19

Small-scale

0.977

High

816982

MTR3
Exosome complex component MTR3

9

0

Small-scale

0.922

High

755005

RRP4
Exosome complex component RRP4

14

13

Small-scale

0.761

High

993685

RRP6
Exosome complex exonuclease RRP6

14

5

Small-scale

0.760

High

865428

CSL4
Exosome complex component CSL4

13

4

Small-scale

0.760

High

993688

RRP42
Exosome complex component RRP42

11

19

Small-scale

0.757

High

993677

RRP40
Exosome complex component RRP40

11

4

Small-scale

0.756

High

993678

SKI7
Superkiller protein 7

9

2

Small-scale

0.752

High

755209

LRP1
Exosome complex protein LRP1

8

0

Small-scale

0.716

High

972923

IMA1
Importin subunit alpha

3

2

Small-scale

0.678

High

993676

RRP44
Exosome complex exonuclease DIS3

1

5

High-throughput

0.665

High

864440

MPP6
M-phase phosphoprotein 6 homolog

4

0

Small-scale

0.653

High

495123

HSP72
Heat shock protein SSA2

3

5

Small-scale

0.650

High

860757

UTP22
U3 small nucleolar RNA-associated protein 22

3

1

High-throughput

0.643

High

748723

ENP1
Essential nuclear protein 1

3

1

High-throughput

0.640

High

979052

DHR1
Probable ATP-dependent RNA helicase DHR1

3

4

High-throughput

0.640

High

863172

NRD1
Protein NRD1

3

0

Small-scale

0.628

High

982896

RRP5
rRNA biogenesis protein RRP5

1

2

High-throughput

0.618

High

492631

HSP71
Heat shock protein SSA1

2

5

Small-scale

0.611

High

512968

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.601

High

628530

SIS1
Protein SIS1

2

1

Small-scale

0.584

High

792607

UTP10
U3 small nucleolar RNA-associated protein 10

2

1

High-throughput

0.584

High

979731

UTP14
U3 small nucleolar RNA-associated protein 14

2

1

High-throughput

0.584

High

987670

NOC4
Nucleolar complex protein 4

2

3

High-throughput

0.584

High

688462

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

0

High-throughput

0.576

High

489682

MPPB
Mitochondrial-processing peptidase subunit beta

2

0

High-throughput

0.563

High

698964

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

Small-scale

0.552

High

769639

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

986146

IMB1
Importin subunit beta-1

1

0

Small-scale

0.537

High

975982

GCN5
Histone acetyltransferase GCN5

1

5

High-throughput

0.536

High

375631

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

3

High-throughput

0.515

High

429779

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.515

High

565797

PHO85
Cyclin-dependent protein kinase PHO85

1

3

High-throughput

0.501

High

601774

RCC1
Guanine nucleotide exchange factor SRM1

1

1

Small-scale

0.501

High

977113

SKY1
Serine/threonine-protein kinase SKY1

1

1

High-throughput

0.501

High

420179

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.493

High

572021

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

0

High-throughput

0.493

High

593272

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.493

High

631688

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.493

High

733200

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.493

High

811315

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.493

High

979275

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

0

High-throughput

0.493

High

509453

CDC24
Cell division control protein 24

1

0

Small-scale

0.480

High

141553

RS9A
Small ribosomal subunit protein uS4A

1

4

High-throughput

0.479

High

408156

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

558291

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

630552

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.479

High

634795

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.479

High

635659

PWP2
Periodic tryptophan protein 2

1

3

High-throughput

0.479

High

663496

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

700107

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

4

High-throughput

0.479

High

707151

DCA13
Protein SOF1

1

2

High-throughput

0.479

High

711083

UTP11
U3 small nucleolar RNA-associated protein 11

1

1

High-throughput

0.479

High

715996

UTP20
U3 small nucleolar RNA-associated protein 20

1

1

High-throughput

0.479

High

767433

UTP7
U3 small nucleolar RNA-associated protein 7

1

2

High-throughput

0.479

High

772690

UTP18
U3 small nucleolar RNA-associated protein 18

1

1

High-throughput

0.479

High

799869

ROK1
ATP-dependent RNA helicase ROK1

1

5

High-throughput

0.479

High

810932

MTR4
ATP-dependent RNA helicase DOB1

1

8

High-throughput

0.479

High

811570

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

1

High-throughput

0.479

High

816917

NOL10
Ribosome biogenesis protein ENP2

1

1

High-throughput

0.479

High

866069

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.479

High

866627

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

3

High-throughput

0.479

High

973687

UTP17
NET1-associated nuclear protein 1

1

7

High-throughput

0.479

High

977858

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

978592

MUS81
Crossover junction endonuclease MUS81

1

1

High-throughput

0.479

High

978642

UTP5
U3 small nucleolar RNA-associated protein 5

1

4

High-throughput

0.479

High

979253

UTP15
U3 small nucleolar RNA-associated protein 15

1

3

High-throughput

0.479

High

983777

FCF1
rRNA-processing protein FCF1

1

2

High-throughput

0.479

High

985430

UTP13
U3 small nucleolar RNA-associated protein 13

1

4

High-throughput

0.479

High

985824

UTP21
U3 small nucleolar RNA-associated protein 21

1

5

High-throughput

0.479

High

986759

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

1

High-throughput

0.479

High

987610

RRP9
Ribosomal RNA-processing protein 9

1

8

High-throughput

0.479

High

988478

BFR2
Protein BFR2

1

1

High-throughput

0.479

High

988646

UTP4
U3 small nucleolar RNA-associated protein 4

1

3

High-throughput

0.479

High

993681

BMS1
Ribosome biogenesis protein BMS1

1

1

High-throughput

0.479

High

993682

FCF2
rRNA-processing protein FCF2

1

1

High-throughput

0.479

High

993683

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

993684

SAS10
Something about silencing protein 10

1

1

High-throughput

0.479

High

993687

UTP12
U3 small nucleolar RNA-associated protein 12

1

4

High-throughput

0.479

High

993689

NOP56
Nucleolar protein 56

1

3

High-throughput

0.479

High

993690

NOP58
Nucleolar protein 58

1

3

High-throughput

0.479

High

993692

NOP14
Nucleolar complex protein 14

1

1

High-throughput

0.479

High

480349

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

571920

SKI3
Superkiller protein 3

1

0

High-throughput

0.458

High

691299

AEP1
ATPase expression protein 1, mitochondrial

1

0

High-throughput

0.458

High

728328

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

756801

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

774289

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

775399

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

861041

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

866217

NM111
Pro-apoptotic serine protease NMA111

1

0

High-throughput

0.458

High

970479

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

978329

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

993365

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

993679

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

993686

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

993691

ISD11
Protein ISD11

1

0

High-throughput

0.458

High

356762

H4
Histone H4

1

2

High-throughput

0.445

High

450212

HSP73
Heat shock protein SSA3

1

5

High-throughput

0.445

High

478571

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.445

High

705734

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

754759

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

978137

HMO1
High mobility group protein 1

1

1

High-throughput

0.445

High

706523

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

716210

SKI2
Antiviral helicase SKI2

1

7

High-throughput

0.437

High

820207

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.437

High

993680

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.437

High

554249

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

2

High-throughput

0.417

High

865932

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.407

High

618520

HXT2
High-affinity glucose transporter HXT2

1

0

High-throughput

0.249

Low

777403

OPT1
Oligopeptide transporter 1

1

0

High-throughput

0.249

Low

977478

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

981510

GFD1
mRNA transport factor GFD1

1

0

High-throughput

0.249

Low

984757

NCW2
Cell wall biogenesis protein NCW2

1

0

High-throughput

0.249

Low

699243

SEC8
Exocyst complex component SEC8

1

0

High-throughput

0.232

Low

761097

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024