Protein: NOP12
Nucleolar protein 12

Gene: NOP12
Organism: Saccharomyces cerevisiae S288C
Interactions: 169
UniProt ID: Q08208

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005730 - nucleolus
GO:0019843 - rRNA binding
GO:0030684 - preribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

742075

NOP4
Nucleolar protein 4

6

19

Small-scale

0.951

High

994052

NOP12
Nucleolar protein 12

3

17

High-throughput

0.834

High

485598

SSBP1
Single-stranded nucleic acid-binding protein

2

19

High-throughput

0.789

High

866277

NOP15
Ribosome biogenesis protein 15

2

18

High-throughput

0.754

High

994063

YRA1
RNA annealing protein YRA1

2

19

Small-scale

0.754

High

744250

MAK5
ATP-dependent RNA helicase MAK5

6

20

High-throughput

0.730

High

764259

NOC2
Nucleolar complex protein 2

5

2

Small-scale

0.711

High

731877

EBP2
rRNA-processing protein EBP2

5

1

Small-scale

0.705

High

550137

CSK21
Casein kinase II subunit alpha

1

19

High-throughput

0.691

High

985907

MRD1
Multiple RNA-binding domain-containing protein 1

1

17

Small-scale

0.691

High

597910

PWP1
Periodic tryptophan protein 1

4

19

High-throughput

0.691

High

994064

MAK21
Ribosome biogenesis protein MAK21

4

8

High-throughput

0.691

High

733956

RPF2
Ribosome biogenesis protein RPF2

4

3

Small-scale

0.683

High

797405

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

1

High-throughput

0.670

High

754207

CIC1
Proteasome-interacting protein CIC1

3

3

High-throughput

0.656

High

976875

HAS1
ATP-dependent RNA helicase HAS1

3

20

High-throughput

0.656

High

982897

RRP5
rRNA biogenesis protein RRP5

3

10

High-throughput

0.656

High

994053

BRX1
Ribosome biogenesis protein BRX1

3

15

High-throughput

0.656

High

634455

SPB1
27S pre-rRNA

3

6

High-throughput

0.646

High

699738

DRS1
ATP-dependent RNA helicase DRS1

3

20

High-throughput

0.646

High

994067

DBP10
ATP-dependent RNA helicase DBP10

3

20

High-throughput

0.646

High

973471

NOG1
Nucleolar GTP-binding protein 1

3

6

Small-scale

0.640

High

593714

DBP4
ATP-dependent RNA helicase HCA4

2

19

High-throughput

0.621

High

676427

XPO1
Exportin-1

1

11

High-throughput

0.618

High

688542

KNS1
Dual specificity protein kinase KNS1

1

17

High-throughput

0.618

High

743467

YPK3
Serine/threonine-protein kinase YPK3

1

13

High-throughput

0.618

High

811934

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

8

High-throughput

0.618

High

964738

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

8

High-throughput

0.618

High

968059

KIN4
Serine/threonine-protein kinase KIN4

1

5

High-throughput

0.618

High

974192

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

16

High-throughput

0.618

High

975918

PKH3
Serine/threonine-protein kinase PKH3

1

11

High-throughput

0.618

High

994062

RTK1
Probable serine/threonine-protein kinase RTK1

1

7

High-throughput

0.618

High

994066

PKH2
Serine/threonine-protein kinase PKH2

1

15

High-throughput

0.618

High

383381

RL25
Large ribosomal subunit protein uL23

1

6

High-throughput

0.618

High

407359

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.618

High

859444

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

6

High-throughput

0.611

High

615187

BUR1
Serine/threonine-protein kinase BUR1

1

13

High-throughput

0.595

High

986479

FKBP4
FK506-binding protein 4

2

5

High-throughput

0.594

High

732254

RRP14
Ribosomal RNA-processing protein 14

2

1

Small-scale

0.586

High

638879

SPB4
ATP-dependent rRNA helicase SPB4

2

19

High-throughput

0.584

High

778873

NOP2
25S rRNA

2

4

Small-scale

0.584

High

860898

PESC
Pescadillo homolog

2

1

High-throughput

0.584

High

994061

NOP53
Ribosome biogenesis protein NOP53

2

4

High-throughput

0.584

High

565798

PHO85
Cyclin-dependent protein kinase PHO85

1

7

High-throughput

0.579

High

810780

SMC3
Structural maintenance of chromosomes protein 3

2

1

High-throughput

0.567

High

748724

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

993172

BUD20
Bud site selection protein 20

2

1

High-throughput

0.558

High

406416

RL15A
Large ribosomal subunit protein eL15A

1

3

High-throughput

0.536

High

829710

RL4B
Large ribosomal subunit protein uL4B

1

8

High-throughput

0.536

High

991191

TSR1
Ribosome biogenesis protein TSR1

1

1

High-throughput

0.536

High

994065

RL7B
Large ribosomal subunit protein uL30B

1

11

High-throughput

0.536

High

704437

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

4

High-throughput

0.533

High

810597

ALB1
Ribosome biogenesis protein ALB1

2

1

High-throughput

0.533

High

730737

DHR2
Probable ATP-dependent RNA helicase DHR2

1

7

High-throughput

0.515

High

420584

SPT2
Protein SPT2

1

0

High-throughput

0.513

High

987098

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.513

High

991541

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

994068

RRP36
rRNA biogenesis protein RRP36

1

0

Small-scale

0.513

High

810450

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.493

High

625987

PTP1
Tyrosine-protein phosphatase 1

1

2

High-throughput

0.489

High

653136

MIG1
Regulatory protein MIG1

1

9

High-throughput

0.489

High

667366

PTP2
Tyrosine-protein phosphatase 2

1

2

High-throughput

0.489

High

704183

DOM34
Protein DOM34

1

1

High-throughput

0.489

High

864620

BRE5
UBP3-associated protein BRE5

1

13

High-throughput

0.489

High

965054

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

7

High-throughput

0.489

High

145794

RL36B
Large ribosomal subunit protein eL36B

1

6

Small-scale

0.481

High

406170

RL36A
Large ribosomal subunit protein eL36A

1

6

Small-scale

0.481

High

141554

RS9A
Small ribosomal subunit protein uS4A

1

5

High-throughput

0.479

High

404719

RL7A
Large ribosomal subunit protein uL30A

1

11

High-throughput

0.479

High

405861

RL26A
Large ribosomal subunit protein uL24A

1

4

High-throughput

0.479

High

408157

RS13
Small ribosomal subunit protein uS15

1

5

High-throughput

0.479

High

413737

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

426182

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

480350

RS6A
Small ribosomal subunit protein eS6A

1

4

High-throughput

0.479

High

482489

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

501259

MAK16
Protein MAK16

1

2

High-throughput

0.479

High

594079

MAK11
Protein MAK11

1

19

Small-scale

0.479

High

630894

NLE1
Ribosome assembly protein 4

1

16

High-throughput

0.479

High

632122

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.479

High

634796

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.479

High

645686

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

667289

RL8B
Large ribosomal subunit protein eL8B

1

6

High-throughput

0.479

High

703126

MRT4
Ribosome assembly factor MRT4

1

3

High-throughput

0.479

High

715496

RRP1
Ribosomal RNA-processing protein 1

1

7

High-throughput

0.479

High

730148

RS27A
Small ribosomal subunit protein eS27A

1

3

High-throughput

0.479

High

746274

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

754922

SSF1
Ribosome biogenesis protein SSF1

1

3

High-throughput

0.479

High

755341

RPF1
Ribosome production factor 1

1

3

High-throughput

0.479

High

757360

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

5

High-throughput

0.479

High

765082

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

12

Small-scale

0.479

High

766604

NOP16
Nucleolar protein 16

1

1

High-throughput

0.479

High

766717

NUG1
Nuclear GTP-binding protein NUG1

1

6

High-throughput

0.479

High

768057

NSA2
Ribosome biogenesis protein NSA2

1

4

High-throughput

0.479

High

776530

RLP7
Ribosome biogenesis protein RLP7

1

11

High-throughput

0.479

High

792608

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

810933

MTR4
ATP-dependent RNA helicase DOB1

1

20

Small-scale

0.479

High

859519

NSA1
Ribosome biogenesis protein NSA1

1

1

High-throughput

0.479

High

864694

NOG2
Nucleolar GTP-binding protein 2

1

6

High-throughput

0.479

High

865626

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

10

High-throughput

0.479

High

866863

RCM1
25S rRNA

1

4

High-throughput

0.479

High

967794

RS15
Small ribosomal subunit protein uS19

1

4

High-throughput

0.479

High

972645

XRN2
5'-3' exoribonuclease 2

1

6

High-throughput

0.479

High

975848

TOM1
E3 ubiquitin-protein ligase TOM1

1

13

High-throughput

0.479

High

977775

ARX1
Probable metalloprotease ARX1

1

4

High-throughput

0.479

High

978441

RRP17
Ribosomal RNA-processing protein 17

1

1

High-throughput

0.479

High

979053

DHR1
Probable ATP-dependent RNA helicase DHR1

1

14

High-throughput

0.479

High

979732

UTP14
U3 small nucleolar RNA-associated protein 14

1

1

High-throughput

0.479

High

980168

ERB1
Ribosome biogenesis protein ERB1

1

11

High-throughput

0.479

High

986583

JIP5
WD repeat-containing protein JIP5

1

13

High-throughput

0.479

High

987645

RRP15
Ribosomal RNA-processing protein 15

1

1

High-throughput

0.479

High

987671

NOC4
Nucleolar complex protein 4

1

8

High-throughput

0.479

High

992538

NOC3
Nucleolar complex-associated protein 3

1

5

High-throughput

0.479

High

992621

RLP24
Ribosome biogenesis protein RLP24

1

3

High-throughput

0.479

High

994054

REXO4
RNA exonuclease 4

1

5

High-throughput

0.479

High

994057

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

994058

RRS1
Regulator of ribosome biosynthesis

1

3

High-throughput

0.479

High

994059

NIP7
60S ribosome subunit biogenesis protein NIP7

1

1

High-throughput

0.479

High

994060

YTM1
Ribosome biogenesis protein YTM1

1

17

High-throughput

0.479

High

994069

NOP58
Nucleolar protein 58

1

3

High-throughput

0.479

High

866070

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.458

High

994070

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

960024

SEN1
Helicase SEN1

1

18

Small-scale

0.445

High

775099

RL34B
Large ribosomal subunit protein eL34B

1

4

Small-scale

0.439

High

953526

RL34A
Large ribosomal subunit protein eL34A

1

4

Small-scale

0.439

High

358288

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

408483

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

6

High-throughput

0.437

High

471287

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

472424

RL31A
Large ribosomal subunit protein eL31A

1

5

High-throughput

0.437

High

478999

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.437

High

480917

RS8A
Small ribosomal subunit protein eS8A

1

6

High-throughput

0.437

High

558292

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

628532

SIS1
Protein SIS1

1

4

High-throughput

0.437

High

663503

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

665087

BMH1
Protein BMH1

1

3

High-throughput

0.437

High

688463

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

700656

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

706524

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

737229

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.437

High

743029

GBLP
Small ribosomal subunit protein RACK1

1

13

High-throughput

0.437

High

752702

RS20
Small ribosomal subunit protein uS10

1

4

High-throughput

0.437

High

762618

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

775274

ULP2
Ubiquitin-like-specific protease 2

1

2

High-throughput

0.437

High

820208

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

841445

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.437

High

859641

LSG1
Large subunit GTPase 1

1

6

High-throughput

0.437

High

860398

EIF2A
Eukaryotic translation initiation factor 2A

1

3

High-throughput

0.437

High

872815

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.437

High

986263

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

991308

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

994055

SGO1
Shugoshin

1

1

High-throughput

0.437

High

512975

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.407

High

769643

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.407

High

524464

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.305

High

604308

MAG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.279

Low

697887

ALK2
Serine/threonine-protein kinase Haspin homolog ALK2

1

0

High-throughput

0.279

Low

865466

ELOA1
Elongin-A

1

0

High-throughput

0.279

Low

978593

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.279

Low

987349

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.279

Low

994056

DIA2
Protein DIA2

1

0

High-throughput

0.279

Low

622902

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.269

Low

748062

GDT1
Divalent cation/proton antiporter GDT1

1

0

High-throughput

0.269

Low

809792

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.269

Low

419507

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.249

Low

705737

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.249

Low

731619

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

756878

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.249

Low

775882

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

977479

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024