Protein: NOB1
20S-pre-rRNA D-site endonuclease NOB1 (EC 3.1.-.-) (NIN1-binding protein) (Pre-rRNA-processing endonuclease NOB1)

Gene: NOB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: Q08444

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0004521 - RNA endonuclease activity
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743032

GBLP
Small ribosomal subunit protein RACK1

3

3

Small-scale

0.847

High

770071

RIO2
Serine/threonine-protein kinase RIO2

14

4

Small-scale

0.758

High

748730

ENP1
Essential nuclear protein 1

12

1

Small-scale

0.756

High

991192

TSR1
Ribosome biogenesis protein TSR1

8

1

Small-scale

0.749

High

995644

PNO1
Pre-rRNA-processing protein PNO1

7

2

Small-scale

0.739

High

413742

RS14A
Small ribosomal subunit protein uS11A

2

1

Small-scale

0.737

High

709388

LTV1
Protein LTV1

6

0

Small-scale

0.693

High

784533

DIM1
Dimethyladenosine transferase

5

0

Small-scale

0.673

High

664558

HRR25
Casein kinase I homolog HRR25

4

0

Small-scale

0.653

High

995640

RIO1
Serine/threonine-protein kinase RIO1

3

4

Small-scale

0.641

High

492660

HSP71
Heat shock protein SSA1

3

1

High-throughput

0.633

High

535289

RS17B
Small ribosomal subunit protein eS17B

1

1

High-throughput

0.618

High

988648

UTP4
U3 small nucleolar RNA-associated protein 4

1

2

Small-scale

0.618

High

995636

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

0

Small-scale

0.614

High

480921

RS8A
Small ribosomal subunit protein eS8A

3

0

Small-scale

0.613

High

408160

RS13
Small ribosomal subunit protein uS15

2

1

High-throughput

0.611

High

706528

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.586

High

645689

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.585

High

333926

ADH1
Alcohol dehydrogenase 1

2

0

High-throughput

0.563

High

482491

RS18A
Small ribosomal subunit protein uS13A

2

0

High-throughput

0.559

High

752705

RS20
Small ribosomal subunit protein uS10

2

0

Small-scale

0.559

High

358291

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.553

High

512999

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

479834

RS4A
Small ribosomal subunit protein eS4A

2

0

Small-scale

0.547

High

860536

SLX9
Ribosome biogenesis protein SLX9

2

0

Small-scale

0.547

High

407595

RS9B
Small ribosomal subunit protein uS4B

1

1

High-throughput

0.536

High

416095

DED1
ATP-dependent RNA helicase DED1

1

1

Small-scale

0.536

High

676435

XPO1
Exportin-1

1

1

High-throughput

0.536

High

995639

PSH1
RING finger protein PSH1

1

1

High-throughput

0.536

High

700658

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.517

High

976877

HAS1
ATP-dependent RNA helicase HAS1

1

2

High-throughput

0.515

High

407364

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

479539

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.513

High

624187

DBP2
ATP-dependent RNA helicase DBP2

1

0

Small-scale

0.513

High

703969

PRS7
26S proteasome regulatory subunit 7 homolog

1

0

Small-scale

0.513

High

659847

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.504

High

614840

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

867925

MPS1
Serine/threonine-protein kinase MPS1

1

1

High-throughput

0.501

High

549517

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.493

High

753968

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.493

High

982902

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.493

High

995643

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.489

High

412902

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

539284

YAK1
Dual specificity protein kinase YAK1

1

0

High-throughput

0.480

High

548564

GCN2
eIF-2-alpha kinase GCN2

1

0

High-throughput

0.480

High

565804

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

765416

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

High-throughput

0.480

High

771595

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

High-throughput

0.480

High

859152

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.480

High

141557

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

367014

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

632126

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

763915

IF2P
Eukaryotic translation initiation factor 5B

1

1

Small-scale

0.479

High

691506

RPN12
26S proteasome regulatory subunit RPN12

1

0

Small-scale

0.460

High

408485

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

426185

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

480353

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

481563

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.458

High

634800

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

635444

BUD23
18S rRNA

1

0

Small-scale

0.458

High

644954

RS5
Small ribosomal subunit protein uS7

1

0

Small-scale

0.458

High

663524

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

691133

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

730152

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

775278

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

792613

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

820210

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

857410

VPS4
Vacuolar protein sorting-associated protein 4

1

0

High-throughput

0.458

High

859447

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

Small-scale

0.458

High

967800

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

978336

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

979058

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

979736

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

987059

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

987676

NOC4
Nucleolar complex protein 4

1

0

High-throughput

0.458

High

991315

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

995638

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

995641

SEC39
Protein transport protein SEC39

1

0

High-throughput

0.458

High

995642

RRP12
Ribosomal RNA-processing protein 12

1

0

Small-scale

0.458

High

495149

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544529

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

769662

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

471292

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

368458

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

675444

PSB5
Proteasome subunit beta type-5

1

0

Small-scale

0.426

High

979679

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.426

High

988598

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.426

High

995637

RS10A
Small ribosomal subunit protein eS10A

2

0

High-throughput

0.318

High

812542

ENT3
Epsin-3

1

0

Small-scale

0.261

Low

858369

SCY1
Protein kinase-like protein SCY1

1

0

High-throughput

0.261

Low

383384

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405865

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

472428

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

762624

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

797092

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.249

Low

382810

RL24A
Large ribosomal subunit protein eL24A

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024