Protein: GIN4
Serine/threonine-protein kinase GIN4 (EC 2.7.11.1) (Growth inhibitory protein 4)

Gene: GIN4
Organism: Saccharomyces cerevisiae S288C
Interactions: 133
UniProt ID: Q12263

Gene Ontology (top 5):
GO:0000920 - septum digestion after cytokinesis
GO:0000921 - septin ring assembly
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

750956

RIM11
Serine/threonine-protein kinase RIM11/MSD1

3

10

High-throughput

0.867

High

339910

CDK1
Cyclin-dependent kinase 1

3

3

Small-scale

0.858

High

711010

HSL1
Probable serine/threonine-protein kinase HSL1

2

17

High-throughput

0.793

High

698362

ELM1
Serine/threonine-protein kinase ELM1

2

17

Small-scale

0.767

High

627709

NAP1
Nucleosome assembly protein

13

3

Small-scale

0.761

High

991731

SHS1
Seventh homolog of septin 1

6

16

Small-scale

0.744

High

690287

CDC3
Cell division control protein 3

5

5

Small-scale

0.722

High

629593

CDC10
Cell division control protein 10

5

9

Small-scale

0.720

High

690567

CDC12
Cell division control protein 12

5

5

Small-scale

0.720

High

690351

CDC11
Cell division control protein 11

4

14

Small-scale

0.702

High

624754

CG23
G2/mitotic-specific cyclin-3

1

2

High-throughput

0.691

High

691219

MKK1
MAP kinase kinase MKK1/SSP32

1

17

High-throughput

0.691

High

744090

PP2C4
Protein phosphatase 2C homolog 4

1

19

High-throughput

0.691

High

964747

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

17

High-throughput

0.691

High

515025

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.647

High

864561

FPK1
Flippase kinase 1

1

17

Small-scale

0.647

High

866772

CRZ1
Transcriptional regulator CRZ1

1

3

High-throughput

0.647

High

1015395

ARP8
Actin-like protein ARP8

1

10

High-throughput

0.647

High

865820

BNI5
Bud neck protein 5

2

1

Small-scale

0.635

High

715604

PP2C1
Protein phosphatase 2C homolog 1

1

20

High-throughput

0.621

High

606177

RAD53
Serine/threonine-protein kinase RAD53

1

16

High-throughput

0.618

High

961522

CDC14
Tyrosine-protein phosphatase CDC14

1

12

Small-scale

0.618

High

1015393

GIN4
Serine/threonine-protein kinase GIN4

1

16

Small-scale

0.618

High

708077

NUF2
Kinetochore protein NUF2

2

11

High-throughput

0.595

High

764020

SAW1
Single-strand annealing weakened protein 1

2

1

High-throughput

0.588

High

972491

PDR12
ATP-dependent permease PDR12

2

0

High-throughput

0.587

High

865222

CA120
CCR4-NOT transcriptional complex subunit CAF120

1

0

High-throughput

0.586

High

367087

HSP82
ATP-dependent molecular chaperone HSP82

1

15

High-throughput

0.575

High

629080

SCJ1
DnaJ-related protein SCJ1

1

5

High-throughput

0.575

High

751101

RCK1
Serine/threonine-protein kinase RCK1

1

20

High-throughput

0.575

High

866559

APJ1
J domain-containing protein APJ1

1

9

High-throughput

0.575

High

705808

HSP78
Heat shock protein 78, mitochondrial

2

4

High-throughput

0.571

High

978100

SPC19
DASH complex subunit SPC19

2

0

High-throughput

0.570

High

773881

BNR1
BNI1-related protein 1

1

5

Small-scale

0.561

High

758722

TEM1
Protein TEM1

1

18

High-throughput

0.553

High

1015222

NBP2
NAP1-binding protein 2

1

2

High-throughput

0.527

High

563993

SEC2
Rab guanine nucleotide exchange factor SEC2

1

4

High-throughput

0.501

High

585880

RDS2
Regulator of drug sensitivity 2

1

2

High-throughput

0.501

High

630664

GLRX1
Glutaredoxin-1

1

2

High-throughput

0.501

High

648342

GYS2
Glycogen [starch] synthase isoform 2

1

1

High-throughput

0.501

High

657145

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

7

High-throughput

0.501

High

748906

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

1

1

Small-scale

0.501

High

775483

DOT5
Peroxiredoxin DOT5

1

4

High-throughput

0.501

High

860175

YG1B
Uncharacterized protein YGR017W

1

1

High-throughput

0.501

High

979227

SEG1
Eisosome protein SEG1

1

1

High-throughput

0.501

High

979617

HFD1
Fatty aldehyde dehydrogenase HFD1

1

2

High-throughput

0.501

High

986130

YL345
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W [Includes: 6-phosphofructo-2-kinase

1

3

High-throughput

0.501

High

992563

CMS1
Protein CMS1

1

1

High-throughput

0.501

High

1015083

SAS10
Something about silencing protein 10

1

1

High-throughput

0.501

High

488506

PRI1
DNA primase small subunit

1

0

High-throughput

0.493

High

704450

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.493

High

865366

VPS75
Vacuolar protein sorting-associated protein 75

1

0

High-throughput

0.493

High

987110

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.493

High

706076

NIP80
Protein NIP100

1

18

High-throughput

0.481

High

866388

NIS1
Protein NIS1

1

1

Small-scale

0.481

High

629790

STE50
Protein STE50

1

0

Small-scale

0.480

High

969347

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.480

High

989239

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.480

High

141584

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

407397

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

408186

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

482516

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

632150

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

663672

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

730176

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

730943

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.479

High

743060

GBLP
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.479

High

751005

KPR2
Ribose-phosphate pyrophosphokinase 2

1

7

High-throughput

0.479

High

752731

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

761110

TCPZ
T-complex protein 1 subunit zeta

1

7

High-throughput

0.479

High

762043

DHH1
ATP-dependent RNA helicase DHH1

1

5

High-throughput

0.479

High

774503

MOB1
DBF2 kinase activator protein MOB1

1

2

High-throughput

0.479

High

902139

H3
Histone H3

1

5

High-throughput

0.479

High

967827

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

984226

HRQ1
ATP-dependent helicase HRQ1

1

3

Small-scale

0.479

High

986284

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

991357

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.479

High

549531

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.470

High

754356

GIC1
GTPase-interacting component 1

1

0

Small-scale

0.460

High

979194

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.460

High

987950

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

1015397

AIM44
Altered inheritance of mitochondria protein 44

1

0

Small-scale

0.460

High

554772

HSP26
Heat shock protein 26

1

0

Small-scale

0.458

High

775903

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

797899

ECO1
N-acetyltransferase ECO1

1

0

Small-scale

0.458

High

812163

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

820236

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

966051

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.458

High

1015365

YL054
Uncharacterized transcriptional regulatory protein YLL054C

1

0

Small-scale

0.458

High

581127

IF5A2
Eukaryotic translation initiation factor 5A-2

1

1

High-throughput

0.457

High

979670

SEC13
Protein transport protein SEC13

1

3

High-throughput

0.457

High

987752

ARV1
Protein ARV1

1

1

High-throughput

0.457

High

492842

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

495305

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

513206

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

681086

HS104
Heat shock protein 104

1

5

High-throughput

0.445

High

695807

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

754811

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.445

High

766277

HSP7E
Heat shock protein SSC3, mitochondrial

1

10

High-throughput

0.445

High

769801

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

773793

6P21
6-phosphofructo-2-kinase 1

1

4

High-throughput

0.445

High

988725

IMH1
Golgin IMH1

1

20

High-throughput

0.439

High

987204

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

383412

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

405887

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

413771

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

471318

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

472453

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

480948

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

700683

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

706558

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

822959

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

996352

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

731450

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.282

High

548008

SEC11
Signal peptidase complex catalytic subunit SEC11

1

0

High-throughput

0.269

Low

373307

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.261

Low

447010

EI2BG
Translation initiation factor eIF2B subunit gamma

1

0

High-throughput

0.261

Low

617243

MBR1
Mitochondrial biogenesis regulation protein 1

1

0

High-throughput

0.261

Low

755352

RPF1
Ribosome production factor 1

1

0

High-throughput

0.261

Low

977649

NUP53
Nucleoporin NUP53

1

0

High-throughput

0.261

Low

1015396

MPD1
Protein disulfide-isomerase MPD1

1

0

High-throughput

0.261

Low

750731

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.251

Low

797095

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

982688

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

993142

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

1015394

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

1015398

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.251

Low

358314

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

426208

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

645714

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

732348

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

812237

ACF4
Assembly-complementing factor 4

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024