Protein: MIA40
Mitochondrial intermembrane space import and assembly protein 40 (Mitochondrial import inner membrane translocase TIM40)

Gene: MIA40
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: P36046

Gene Ontology (top 5):
GO:0003756 - protein disulfide isomerase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

654994

ERV1
Mitochondrial FAD-linked sulfhydryl oxidase ERV1

17

1

Small-scale

0.763

High

251770

TIM9
Mitochondrial import inner membrane translocase subunit TIM9

11

0

Small-scale

0.722

High

731676

TIM10
Mitochondrial import inner membrane translocase subunit TIM10

5

2

Small-scale

0.721

High

731672

TIM13
Mitochondrial import inner membrane translocase subunit TIM13

4

2

Small-scale

0.680

High

731687

COX17
Cytochrome c oxidase copper chaperone

5

0

Small-scale

0.674

High

731673

ATP23
Mitochondrial inner membrane protease ATP23

2

0

Small-scale

0.607

High

731644

MIA40
Mitochondrial intermembrane space import and assembly protein 40

2

1

Small-scale

0.595

High

731663

CCS1
Superoxide dismutase 1 copper chaperone

2

1

Small-scale

0.595

High

731645

COXM1
COX assembly mitochondrial protein

2

0

Small-scale

0.592

High

619730

TOM40
Mitochondrial import receptor subunit TOM40

2

0

Small-scale

0.592

High

698616

TIM12
Mitochondrial import inner membrane translocase subunit TIM12

2

2

Small-scale

0.585

High

490870

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

493665

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.571

High

731675

TIM8
Mitochondrial import inner membrane translocase subunit TIM8

2

3

Small-scale

0.571

High

510891

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.558

High

731691

COX19
Cytochrome c oxidase assembly protein COX19

2

0

Small-scale

0.547

High

731646

HOT13
Helper of Tim protein 13

1

0

Small-scale

0.537

High

731670

TOM22
Mitochondrial import receptor subunit TOM22

2

0

Small-scale

0.528

High

731666

GPX3
Glutathione peroxidase-like peroxiredoxin HYR1

1

0

Small-scale

0.505

High

333309

CYC1
Cytochrome c isoform 1

1

1

Small-scale

0.501

High

333337

CYC7
Cytochrome c isoform 2

1

1

Small-scale

0.501

High

614607

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

731671

TIM21
Mitochondrial import inner membrane translocase subunit TIM21

1

0

Small-scale

0.480

High

478087

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.479

High

731680

MIX17
Mitochondrial intermembrane space cysteine motif-containing protein MIX17

1

2

Small-scale

0.479

High

731688

TIM22
Mitochondrial import inner membrane translocase subunit TIM22

1

1

Small-scale

0.479

High

373230

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

424065

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

Small-scale

0.458

High

731647

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

731657

TIM17
Mitochondrial import inner membrane translocase subunit TIM17

1

0

Small-scale

0.458

High

731677

PT191
Mitochondrial protein PET191

1

0

Small-scale

0.458

High

333588

CYB2
L-lactate dehydrogenase

1

1

Small-scale

0.445

High

423005

TOM70
Mitochondrial import receptor subunit TOM70

1

1

Small-scale

0.445

High

427230

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

2

High-throughput

0.445

High

575940

ADT2
ADP,ATP carrier protein 2

1

2

High-throughput

0.445

High

619559

MPCP
Mitochondrial phosphate carrier protein

1

2

High-throughput

0.445

High

675258

LCF1
Long-chain-fatty-acid--CoA ligase 1

1

1

High-throughput

0.445

High

687636

OAC1
Mitochondrial oxaloacetate transport protein

1

3

High-throughput

0.445

High

694461

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

705036

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

715778

MDJ1
DnaJ homolog 1, mitochondrial

1

1

High-throughput

0.445

High

731654

HXT6
High-affinity hexose transporter HXT6

1

3

High-throughput

0.445

High

731655

HXT7
High-affinity hexose transporter HXT7

1

3

High-throughput

0.445

High

731656

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

731660

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

731665

FLX1
Mitochondrial FAD carrier protein FLX1

1

3

High-throughput

0.445

High

661901

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

336218

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

Small-scale

0.426

High

336675

SODC
Superoxide dismutase [Cu-Zn]

1

0

Small-scale

0.426

High

341990

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.426

High

429195

SEC4
Ras-related protein SEC4

1

0

High-throughput

0.426

High

534384

DPM1
Dolichol-phosphate mannosyltransferase

1

0

High-throughput

0.426

High

677082

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.426

High

696493

TOR2
Serine/threonine-protein kinase TOR2

1

0

High-throughput

0.426

High

704015

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

0

High-throughput

0.426

High

730614

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.426

High

731649

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.426

High

731651

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.426

High

731659

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.426

High

731664

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

0

High-throughput

0.426

High

731686

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

Small-scale

0.426

High

141661

YA11B
Truncated transposon Ty1-A Gag-Pol polyprotein

1

7

High-throughput

0.407

High

360840

TBB
Tubulin beta chain

1

2

High-throughput

0.407

High

454280

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.407

High

454593

TBA3
Tubulin alpha-3 chain

1

3

High-throughput

0.407

High

472542

YD14B
Transposon Ty1-DR5 Gag-Pol polyprotein

1

7

High-throughput

0.407

High

472549

YD15B
Transposon Ty1-DR6 Gag-Pol polyprotein

1

7

High-throughput

0.407

High

560949

EF3A
Elongation factor 3A

1

1

High-throughput

0.407

High

628699

PHO84
Inorganic phosphate transporter PHO84

1

4

High-throughput

0.407

High

636103

FIG2
Factor-induced gene 2 protein

1

2

High-throughput

0.407

High

690480

HXT3
Low-affinity glucose transporter HXT3

1

3

High-throughput

0.407

High

690505

HXT4
Low-affinity glucose transporter HXT4

1

3

High-throughput

0.407

High

731658

BDH1
(R,R)-butanediol dehydrogenase

1

1

High-throughput

0.407

High

731662

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

731674

EF3B
Elongation factor 3B

1

1

High-throughput

0.407

High

731678

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

7

High-throughput

0.407

High

731679

YE12B
Transposon Ty1-ER2 Gag-Pol polyprotein

1

7

High-throughput

0.407

High

731681

YD11B
Transposon Ty1-DR1 Gag-Pol polyprotein

1

7

High-throughput

0.407

High

731689

GPR1
G protein-coupled receptor GPR1

1

1

High-throughput

0.407

High

731692

YD12B
Transposon Ty1-DR3 Gag-Pol polyprotein

1

7

High-throughput

0.407

High

594312

PP11
Serine/threonine-protein phosphatase PP1-1

3

0

High-throughput

0.335

High

731669

SA155
SIT4-associating protein SAP155

2

0

High-throughput

0.298

High

633128

MAS5
Mitochondrial protein import protein MAS5

2

0

High-throughput

0.288

High

333761

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.279

Low

731661

IMB4
Importin subunit beta-4

1

0

High-throughput

0.279

Low

710053

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.269

Low

731653

VPS29
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.269

Low

731682

AIM32
Altered inheritance of mitochondria protein 32

1

0

Small-scale

0.261

Low

731648

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.249

Low

731683

POC1
Proteasome chaperone 1

1

0

High-throughput

0.249

Low

423451

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.232

Low

503076

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.232

Low

580810

GAP1
General amino-acid permease GAP1

1

0

High-throughput

0.232

Low

596966

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.232

Low

604386

CLH
Clathrin heavy chain

1

0

High-throughput

0.232

Low

625997

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.232

Low

653835

KRE2
Glycolipid 2-alpha-mannosyltransferase

1

0

High-throughput

0.232

Low

696444

FIMB
Fimbrin

1

0

High-throughput

0.232

Low

731650

IST2
Increased sodium tolerance protein 2

1

0

High-throughput

0.232

Low

731652

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.232

Low

731667

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.232

Low

731668

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.232

Low

731684

SUE1
Protein SUE1, mitochondrial

1

0

Small-scale

0.232

Low

731685

PUN1
Protein PUN1

1

0

High-throughput

0.232

Low

731690

NOP58
Nucleolar protein 58

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024