Protein: GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (GFAT) (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (Hexosephosphate aminotransferase)

Gene: GFA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 215
UniProt ID: P14742

Gene Ontology (top 5):
GO:0004360 - glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0005829 - cytosol
GO:0006002 - fructose 6-phosphate metabolic process
GO:0006047 - UDP-N-acetylglucosamine metabolic process
GO:0006048 - UDP-N-acetylglucosamine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

540150

GCN5
Histone acetyltransferase GCN5

2

7

High-throughput

0.628

High

540089

RPN10
26S proteasome regulatory subunit RPN10

2

3

High-throughput

0.621

High

502946

SEC7
Protein transport protein SEC7

2

0

High-throughput

0.595

High

477099

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

4

High-throughput

0.595

High

540114

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

4

High-throughput

0.584

High

540111

EMW1
Essential for maintenance of the cell wall protein 1

3

3

High-throughput

0.579

High

341640

ARGI
Arginase

2

0

High-throughput

0.576

High

365702

HSP82
ATP-dependent molecular chaperone HSP82

2

6

High-throughput

0.571

High

510118

SSB1
Ribosome-associated molecular chaperone SSB1

2

10

High-throughput

0.571

High

540040

RAD51
DNA repair protein RAD51

2

2

High-throughput

0.567

High

540050

IMB3
Importin subunit beta-3

2

1

High-throughput

0.567

High

480986

RL23B
Large ribosomal subunit protein uL14B

2

0

High-throughput

0.559

High

540038

RS2
Small ribosomal subunit protein uS5

2

0

Small-scale

0.559

High

540183

RUVB2
RuvB-like protein 2

2

2

High-throughput

0.558

High

540103

SSB2
Ribosome-associated molecular chaperone SSB2

2

10

High-throughput

0.552

High

343265

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

1

High-throughput

0.536

High

372793

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

2

High-throughput

0.536

High

540128

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

540141

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

540182

AHA1
Hsp90 co-chaperone AHA1

1

1

High-throughput

0.536

High

540155

RUVB1
RuvB-like protein 1

2

2

High-throughput

0.521

High

498421

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.513

High

540065

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.513

High

540074

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.513

High

540082

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.513

High

540086

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

540098

FHP
Flavohemoprotein

1

0

High-throughput

0.513

High

540126

SGF73
SAGA-associated factor 73

1

0

High-throughput

0.513

High

540135

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.513

High

540161

ISR1
Serine/threonine-protein kinase ISR1

1

0

High-throughput

0.513

High

539937

EI2BA
Translation initiation factor eIF2B subunit alpha

1

1

High-throughput

0.500

High

540056

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.500

High

540080

IMB2
Importin subunit beta-2

1

1

High-throughput

0.500

High

540140

AP1M1
AP-1 complex subunit mu-1-I

1

1

High-throughput

0.500

High

540187

AP2M
AP-2 complex subunit mu

1

1

High-throughput

0.500

High

429608

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.489

High

439956

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.489

High

454543

TBA3
Tubulin alpha-3 chain

1

3

High-throughput

0.489

High

539292

KSS1
Mitogen-activated protein kinase KSS1

1

1

High-throughput

0.489

High

540025

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

4

High-throughput

0.489

High

540026

DBF2
Cell cycle protein kinase DBF2

1

2

High-throughput

0.489

High

540047

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.489

High

540066

SPT7
Transcriptional activator SPT7

1

3

High-throughput

0.489

High

540071

KDX1
Serine/threonine-protein kinase KDX1

1

2

High-throughput

0.489

High

540078

TAF5
Transcription initiation factor TFIID subunit 5

1

2

High-throughput

0.489

High

540079

CHK1
Serine/threonine-protein kinase CHK1

1

3

High-throughput

0.489

High

540084

KPR3
Ribose-phosphate pyrophosphokinase 3

1

1

High-throughput

0.489

High

540105

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

540124

INO80
Chromatin-remodeling ATPase INO80

1

1

High-throughput

0.489

High

540138

ARP4
Actin-related protein 4

1

1

High-throughput

0.489

High

540185

GLT1
Glutamate synthase [NADH]

1

2

High-throughput

0.489

High

540024

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.479

High

540037

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.479

High

540168

SHS1
Seventh homolog of septin 1

1

0

High-throughput

0.479

High

477593

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

2

High-throughput

0.479

High

540034

SIS1
Protein SIS1

1

6

High-throughput

0.479

High

540061

SMY2
Protein SMY2

1

3

High-throughput

0.479

High

540097

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

540133

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.479

High

357848

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

382918

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

402864

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

Small-scale

0.458

High

406737

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

407689

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

425725

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

470823

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

471987

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

479888

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

481586

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.458

High

482045

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

540043

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

540058

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

540060

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

540064

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

540070

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

540081

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.458

High

540085

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

540118

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

540142

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

540156

HMO1
High mobility group protein 1

1

0

High-throughput

0.458

High

540171

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

540174

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

540117

CLA4
Serine/threonine-protein kinase CLA4

1

3

High-throughput

0.457

High

540021

GBB
Guanine nucleotide-binding protein subunit beta

1

3

High-throughput

0.457

High

540022

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

2

High-throughput

0.457

High

540032

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

1

High-throughput

0.457

High

540039

DMC1
Meiotic recombination protein DMC1

1

2

High-throughput

0.457

High

540094

DUN1
DNA damage response protein kinase DUN1

1

1

High-throughput

0.457

High

540109

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.457

High

540153

WDR59
Maintenance of telomere capping protein 5

1

5

High-throughput

0.457

High

540159

SPC24
Kinetochore protein SPC24

1

1

High-throughput

0.457

High

367523

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.445

High

490202

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.445

High

493089

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

540016

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.445

High

540027

NPR1
Nitrogen permease reactivator protein

1

2

High-throughput

0.445

High

540115

NMD5
Nonsense-mediated mRNA decay protein 5

1

1

High-throughput

0.445

High

540129

HCH1
Hsp90 co-chaperone HCH1

1

1

High-throughput

0.445

High

540173

HRK1
Serine/threonine-protein kinase HRK1

1

2

High-throughput

0.445

High

540057

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

0

High-throughput

0.438

High

454156

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.437

High

540029

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

4

High-throughput

0.437

High

540042

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

540048

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

540062

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.437

High

540073

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

540088

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.437

High

540106

FIS1
Mitochondrial fission 1 protein

1

1

Small-scale

0.437

High

540137

H3
Histone H3

1

1

High-throughput

0.437

High

540139

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

540162

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

424984

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.426

High

540019

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.426

High

540033

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.426

High

540090

SKN7
Transcription factor SKN7

1

0

High-throughput

0.426

High

540092

ASPG1
L-asparaginase 1

1

0

High-throughput

0.426

High

540095

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

High-throughput

0.426

High

540122

MDS3
Negative regulator of sporulation MDS3

1

0

High-throughput

0.426

High

540134

SIW14
Inositol phosphatase SIW14

1

0

High-throughput

0.426

High

540146

FDC1
Ferulic acid decarboxylase 1

1

0

High-throughput

0.426

High

540149

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.426

High

540172

FOLE
Folylpolyglutamate synthase

1

0

High-throughput

0.426

High

339404

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.407

High

412509

CDC7
Cell division control protein 7

1

4

Small-scale

0.407

High

477852

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.407

High

540044

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.407

High

540049

MCM5
Minichromosome maintenance protein 5

1

3

High-throughput

0.407

High

540053

APE2
Aminopeptidase 2, mitochondrial

1

2

High-throughput

0.407

High

540067

MDJ1
DnaJ homolog 1, mitochondrial

1

5

High-throughput

0.407

High

540087

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.407

High

540101

PIC2
Mitochondrial phosphate carrier protein 2

1

1

High-throughput

0.407

High

540130

RM22
Large ribosomal subunit protein uL22m

1

1

High-throughput

0.407

High

540131

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.407

High

540158

UTP15
U3 small nucleolar RNA-associated protein 15

1

4

High-throughput

0.407

High

540166

SSK1
Osmolarity two-component system protein SSK1

1

1

High-throughput

0.407

High

540178

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.407

High

540181

ARP7
Actin-related protein 7

1

1

High-throughput

0.407

High

540188

DUF1
DUB-associated factor 1

1

4

High-throughput

0.407

High

440849

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

2

0

High-throughput

0.328

High

540072

EF1G2
Elongation factor 1-gamma 2

2

0

High-throughput

0.307

High

540077

GLYC
Serine hydroxymethyltransferase, cytosolic

2

0

High-throughput

0.307

High

540083

RMD9L
RNA-binding protein RMD9-like, mitochondrial

2

0

High-throughput

0.307

High

540108

LCB2
Serine palmitoyltransferase 2

2

0

High-throughput

0.307

High

524129

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.305

High

516787

SST2
Protein SST2

1

0

High-throughput

0.279

Low

540041

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.279

Low

540052

ARP2
Actin-related protein 2

1

0

High-throughput

0.279

Low

540091

SPT8
Transcription factor SPT8

1

0

High-throughput

0.279

Low

540110

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.279

Low

540119

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.279

Low

540120

MSN5
Protein MSN5

1

0

High-throughput

0.279

Low

540125

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.279

Low

540169

VPS13
Intermembrane lipid transfer protein VPS13

1

0

High-throughput

0.279

Low

540180

IES3
Ino eighty subunit 3

1

0

High-throughput

0.279

Low

540186

SUS1
Transcription and mRNA export factor SUS1

1

0

High-throughput

0.279

Low

540020

CLC1
Clathrin light chain

1

0

High-throughput

0.269

Low

540031

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.269

Low

540059

PDC2
Protein PDC2

1

0

High-throughput

0.269

Low

540151

CEF1
Pre-mRNA-splicing factor CEF1

1

0

High-throughput

0.269

Low

540164

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.269

Low

540036

CDC10
Cell division control protein 10

1

0

High-throughput

0.261

Low

375244

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

540068

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

540069

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

540075

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

540076

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

540099

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.249

Low

540107

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

540112

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

540113

SET4
SET domain-containing protein 4

1

0

Small-scale

0.249

Low

540116

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

540145

ESP1
Separin

1

0

High-throughput

0.249

Low

540154

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

540157

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

540170

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

141711

THP2
THO complex subunit THP2

1

0

High-throughput

0.232

Low

141817

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.232

Low

427166

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.232

Low

531653

DHAS
Aspartate-semialdehyde dehydrogenase

1

0

High-throughput

0.232

Low

540017

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

540018

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.232

Low

540023

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.232

Low

540028

SEC15
Exocyst complex component SEC15

1

0

High-throughput

0.232

Low

540030

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.232

Low

540035

MSH3
DNA mismatch repair protein MSH3

1

0

High-throughput

0.232

Low

540045

NAM9
Small ribosomal subunit protein uS4m

1

0

High-throughput

0.232

Low

540046

LAC1
Ceramide synthase LAC1

1

0

High-throughput

0.232

Low

540051

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.232

Low

540054

GSH1
Glutamate--cysteine ligase

1

0

High-throughput

0.232

Low

540055

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

540063

MFT1
THO complex subunit MFT1

1

0

High-throughput

0.232

Low

540093

HXT7
High-affinity hexose transporter HXT7

1

0

High-throughput

0.232

Low

540096

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.232

Low

540100

FMP52
Protein FMP52, mitochondrial

1

0

High-throughput

0.232

Low

540102

MGDP1
Putative magnesium-dependent phosphatase YER134C

1

0

High-throughput

0.232

Low

540104

VID27
Vacuolar import and degradation protein 27

1

0

High-throughput

0.232

Low

540121

NIF3
NGG1-interacting factor 3

1

0

High-throughput

0.232

Low

540123

ARI1
NADPH-dependent aldehyde reductase ARI1

1

0

High-throughput

0.232

Low

540127

MPA43
Protein MPA43

1

0

High-throughput

0.232

Low

540132

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low

540136

DOS2
Protein DOS2

1

0

High-throughput

0.232

Low

540143

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.232

Low

540144

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.232

Low

540147

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.232

Low

540148

PIR1
Cell wall mannoprotein PIR1

1

0

High-throughput

0.232

Low

540152

ARX1
Probable metalloprotease ARX1

1

0

High-throughput

0.232

Low

540160

YL287
Uncharacterized protein YLR287C

1

0

High-throughput

0.232

Low

540163

FKBP4
FK506-binding protein 4

1

0

High-throughput

0.232

Low

540165

UBX5
UBX domain-containing protein 5

1

0

High-throughput

0.232

Low

540167

NOP6
Nucleolar protein 6

1

0

High-throughput

0.232

Low

540175

YO352
Uncharacterized protein YOR352W

1

0

High-throughput

0.232

Low

540176

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.232

Low

540177

NMD4
Nonsense-mediated decay protein 4

1

0

High-throughput

0.232

Low

540179

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.232

Low

540184

NOP58
Nucleolar protein 58

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024