Protein: PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13)

Gene: PRP16
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: P15938

Gene Ontology (top 5):
GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0000378 - RNA exon ligation
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554210

BRR2
Pre-mRNA-splicing helicase BRR2

3

19

Small-scale

0.872

High

554201

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

13

Small-scale

0.757

High

554198

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

13

High-throughput

0.618

High

554211

PRP8
Pre-mRNA-splicing factor 8

1

8

High-throughput

0.618

High

554213

NCBP1
Nuclear cap-binding protein complex subunit 1

1

4

High-throughput

0.618

High

554231

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

13

High-throughput

0.618

High

554235

CWC22
Pre-mRNA-splicing factor CWC22

1

3

High-throughput

0.618

High

554200

ISY1
Pre-mRNA-splicing factor ISY1

2

4

Small-scale

0.584

High

554221

NTC20
Pre-mRNA-splicing factor NTC20

2

3

Small-scale

0.584

High

554236

PAP2
Poly(A) RNA polymerase protein 2

2

3

Small-scale

0.526

High

554239

NOP13
Nucleolar protein 13

1

13

High-throughput

0.515

High

554202

BUD31
Pre-mRNA-splicing factor BUD31

1

5

High-throughput

0.479

High

554203

PRP45
Pre-mRNA-processing protein 45

1

8

High-throughput

0.479

High

554204

YJU2
Splicing factor YJU2

1

4

High-throughput

0.479

High

554207

PRP19
Pre-mRNA-processing factor 19

1

18

High-throughput

0.479

High

554215

SN114
Pre-mRNA-splicing factor SNU114

1

11

High-throughput

0.479

High

554219

SLT11
Pre-mRNA-splicing factor SLT11

1

2

High-throughput

0.479

High

554226

MSL1
U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.479

High

554227

PRP17
Pre-mRNA-processing factor 17

1

18

High-throughput

0.479

High

554233

SYF2
Pre-mRNA-splicing factor SYF2

1

3

High-throughput

0.479

High

554238

CWC25
Pre-mRNA-splicing factor CWC25

1

2

High-throughput

0.479

High

554243

CWC21
Pre-mRNA-splicing factor CWC21

1

2

High-throughput

0.479

High

554244

CEF1
Pre-mRNA-splicing factor CEF1

1

11

High-throughput

0.479

High

554245

CWC15
Pre-mRNA-splicing factor CWC15

1

2

High-throughput

0.479

High

554246

SYF1
Pre-mRNA-splicing factor SYF1

1

20

High-throughput

0.479

High

554247

SN309
Pre-mRNA-splicing factor SNT309

1

2

High-throughput

0.479

High

554251

NCBP2
Nuclear cap-binding protein subunit 2

1

9

High-throughput

0.479

High

554252

RU2A
U2 small nuclear ribonucleoprotein A'

1

13

High-throughput

0.479

High

554253

CWC2
Pre-mRNA-splicing factor CWC2

1

10

High-throughput

0.479

High

554254

YRA1
RNA annealing protein YRA1

1

6

High-throughput

0.479

High

554256

CLF1
Pre-mRNA-splicing factor CLF1

1

19

High-throughput

0.479

High

554258

PRP46
Pre-mRNA-splicing factor PRP46

1

18

High-throughput

0.479

High

549585

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

554222

KIC1
Serine/threonine-protein kinase KIC1

1

1

High-throughput

0.457

High

554241

UBC7
Ubiquitin-conjugating enzyme E2 7

1

5

High-throughput

0.457

High

490229

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

510147

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

554209

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

554225

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

554248

DIB1
Spliceosomal protein DIB1

1

0

High-throughput

0.438

High

141713

THP2
THO complex subunit THP2

1

1

High-throughput

0.437

High

554199

HPR1
THO complex subunit HPR1

1

1

High-throughput

0.437

High

554205

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

554208

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

8

High-throughput

0.437

High

554212

MFT1
THO complex subunit MFT1

1

1

High-throughput

0.437

High

554237

BRE5
UBP3-associated protein BRE5

1

6

High-throughput

0.437

High

554240

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

8

High-throughput

0.437

High

141795

YL462
Putative uncharacterized protein YLR462W

1

2

High-throughput

0.417

High

554214

UTP20
U3 small nucleolar RNA-associated protein 20

1

2

High-throughput

0.417

High

554217

CCL1
Cyclin CCL1

1

2

High-throughput

0.417

High

554229

RSF2
Respiration factor 2

1

2

High-throughput

0.417

High

554234

RBG2
Ribosome-interacting GTPase 2

1

3

High-throughput

0.417

High

554249

RRP44
Exosome complex exonuclease DIS3

1

2

High-throughput

0.417

High

554255

IQG1
Ras GTPase-activating-like protein IQG1

1

1

High-throughput

0.417

High

554232

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.269

Low

336192

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

411212

LEU1
2-isopropylmalate synthase

1

0

High-throughput

0.249

Low

478655

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.249

Low

554206

MLS1
Malate synthase 1

1

0

High-throughput

0.249

Low

554218

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

554224

GDI1
Rab GDP-dissociation inhibitor

1

0

High-throughput

0.249

Low

141894

YP177
Putative uncharacterized protein YPR177C

1

0

High-throughput

0.238

Low

554216

YKH5
Uncharacterized protein YKL075C

1

0

High-throughput

0.238

Low

554220

UMP1
Proteasome maturation factor UMP1

1

0

High-throughput

0.238

Low

554223

MDM31
Mitochondrial distribution and morphology protein 31

1

0

High-throughput

0.238

Low

554228

MTHR1
Methylenetetrahydrofolate reductase 1

1

0

High-throughput

0.238

Low

554230

DOHH
Deoxyhypusine hydroxylase

1

0

High-throughput

0.238

Low

554242

YP067
Uncharacterized protein YPL067C

1

0

High-throughput

0.238

Low

554250

CRT10
Protein CRT10

1

0

High-throughput

0.238

Low

554257

APTH1
Acyl-protein thioesterase 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024