Protein: CENPH
Inner kinetochore subunit MCM16 (CENP-H homolog) (Constitutive centromere-associated network protein MCM16) (Minichromosome maintenance protein 16)

Gene: CENPH, MCM16
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: Q12262

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0034087 - establishment of mitotic sister chromatid cohesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

812585

CENPK
Inner kinetochore subunit MCM22

12

0

Small-scale

0.727

High

1015390

CENPI
Inner kinetochore subunit CTF3

9

0

Small-scale

0.718

High

748308

CENPU
Inner kinetochore subunit AME1

6

0

Small-scale

0.696

High

861324

CENPQ
Inner kinetochore subunit OKP1

6

0

Small-scale

0.696

High

988574

CENPO
Inner kinetochore subunit MCM21

5

0

Small-scale

0.684

High

775902

DSN1
Kinetochore-associated protein DSN1

5

0

Small-scale

0.676

High

972082

CENPP
Inner kinetochore subunit CTF19

5

0

Small-scale

0.666

High

1015388

NKP1
Inner kinetochore subunit NKP1

4

0

Small-scale

0.658

High

763962

MTW1
Kinetochore-associated protein MTW1

4

0

Small-scale

0.653

High

757233

CENPN
Inner kinetochore subunit CHL4

4

0

Small-scale

0.649

High

798071

CENPT
Inner kinetochore subunit CNN1

3

0

Small-scale

0.638

High

747538

CENPL
Inner kinetochore subunit IML3

3

0

Small-scale

0.634

High

986228

NKP2
Inner kinetochore subunit NKP2

3

0

Small-scale

0.630

High

775290

ULP2
Ubiquitin-like-specific protease 2

2

0

Small-scale

0.622

High

860967

DAM1
DASH complex subunit DAM1

2

0

Small-scale

0.565

High

812451

NNF1
Kinetochore-associated protein NNF1

2

0

Small-scale

0.547

High

1015108

NSL1
Kinetochore-associated protein NSL1

2

0

Small-scale

0.547

High

1015217

PSH1
RING finger protein PSH1

2

0

Small-scale

0.547

High

730942

CENPA
Histone H3-like centromeric protein CSE4

2

0

Small-scale

0.528

High

356789

H4
Histone H4

1

0

High-throughput

0.493

High

635057

RDS1
Regulator of drug sensitivity 1

1

0

High-throughput

0.486

High

368762

GCN4
General control transcription factor GCN4

1

0

High-throughput

0.460

High

436851

SWI5
Transcriptional factor SWI5

1

0

High-throughput

0.460

High

514602

BIK1
Nuclear fusion protein BIK1

1

0

High-throughput

0.460

High

599936

RE107
Recombination protein 107

1

0

High-throughput

0.460

High

691183

MEI5
Meiosis protein 5

1

0

High-throughput

0.460

High

697879

YBB0
Uncharacterized protein YBL010C

1

0

High-throughput

0.460

High

700810

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.460

High

702731

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

759107

POP2
Poly(A) ribonuclease POP2

1

0

High-throughput

0.460

High

766842

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

777422

YAP4
AP-1-like transcription factor YAP4

1

0

High-throughput

0.460

High

778478

MAD1
Spindle assembly checkpoint component MAD1

1

0

High-throughput

0.460

High

858694

PPT1
Serine/threonine-protein phosphatase T

1

0

High-throughput

0.460

High

935988

DAD4
DASH complex subunit DAD4

1

0

High-throughput

0.460

High

961942

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.460

High

979277

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

0

High-throughput

0.460

High

988462

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

993938

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.460

High

1015323

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.460

High

663671

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

859866

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

1015391

CENPW
Inner kinetochore subunit WIP1

1

0

Small-scale

0.458

High

695806

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

454502

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

492841

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

513205

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

774092

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.426

High

859854

DUO1
DASH complex subunit DUO1

1

0

High-throughput

0.426

High

1015386

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.426

High

562304

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.407

High

562455

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.407

High

797688

FAR7
Factor arrest protein 7

2

0

High-throughput

0.319

High

704975

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.269

Low

964549

ARG56
Protein ARG5,6, mitochondrial [Cleaved into: N-acetyl-gamma-glutamyl-phosphate reductase

1

0

High-throughput

0.269

Low

141764

THP2
THO complex subunit THP2

1

0

High-throughput

0.251

Low

145923

YO304
Uncharacterized protein YOR304C-A

1

0

High-throughput

0.251

Low

629789

STE50
Protein STE50

1

0

High-throughput

0.251

Low

688949

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

756665

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.251

Low

759281

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.251

Low

766509

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.251

Low

861133

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.251

Low

1015379

NYV1
Vacuolar v-SNARE NYV1

1

0

High-throughput

0.251

Low

1015387

CLF1
Pre-mRNA-splicing factor CLF1

1

0

High-throughput

0.251

Low

1015389

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.251

Low

1015392

CENPX
Inner kinetochore subunit MHF2

1

0

Small-scale

0.249

Low

342142

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

804927

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024