Protein: SKP1
Suppressor of kinetochore protein 1 (Centromere DNA-binding protein complex CBF3 subunit D) (E3 ubiquitin ligase complex SCF subunit SKP1)

Gene: SKP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 163
UniProt ID: P52286

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000278 - mitotic cell cycle
GO:0000409 - regulation of transcription by galactose
GO:0000776 - kinetochore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

431143

CDC4
Cell division control protein 4

28

20

Small-scale

0.993

High

853191

CDC53
Cell division control protein 53

28

20

Small-scale

0.993

High

624307

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

20

20

Small-scale

0.991

High

759309

MET30
F-box protein MET30

21

20

Small-scale

0.989

High

810419

DAS1
F-box protein DAS1

6

1

Small-scale

0.947

High

853172

UFO1
Ubiquitin ligase complex F-box protein UFO1

11

0

Small-scale

0.928

High

791217

SKP2
F-box protein SKP2

7

0

Small-scale

0.913

High

853189

DIA2
Protein DIA2

7

0

Small-scale

0.913

High

853177

MDM30
Mitochondrial distribution and morphology protein 30

6

0

Small-scale

0.898

High

778654

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

6

0

Small-scale

0.894

High

853175

MFB1
Mitochondrial F-box protein MFB1

5

0

Small-scale

0.868

High

853164

RUB1
NEDD8-like protein RUB1

3

1

Small-scale

0.833

High

853149

SKP1
Suppressor of kinetochore protein 1

2

15

Small-scale

0.831

High

853188

SGT1
Protein SGT1

12

1

Small-scale

0.763

High

853198

HRT3
F-box protein HRT3

8

10

Small-scale

0.752

High

811766

RAV1
Regulator of V-ATPase in vacuolar membrane protein 1

9

1

Small-scale

0.750

High

716133

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

14

0

Small-scale

0.733

High

539480

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

6

4

Small-scale

0.730

High

853187

RBX1
RING-box protein HRT1

6

3

Small-scale

0.727

High

853174

ROY1
Non-SCF-type F-box protein ROY1

11

0

Small-scale

0.725

High

749020

SAF1
SCF-associated factor 1

4

1

Small-scale

0.701

High

853182

YL352
F-box protein YLR352W

6

0

Small-scale

0.698

High

762728

RCY1
Recyclin-1

8

1

Small-scale

0.690

High

751492

SIC1
Protein SIC1

5

0

Small-scale

0.685

High

853165

RAV2
Regulator of V-ATPase in vacuolar membrane protein 2

5

0

Small-scale

0.684

High

853163

YD131
F-box protein YDR131C

3

1

Small-scale

0.678

High

853183

YD306
F-box protein YDR306C

3

1

Small-scale

0.678

High

731223

YPT52
GTP-binding protein YPT52

4

0

Small-scale

0.669

High

593402

CG12
G1/S-specific cyclin CLN2

3

6

Small-scale

0.650

High

691915

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

4

0

Small-scale

0.648

High

853178

UCC1
F-box protein UCC1

3

0

Small-scale

0.643

High

747769

AMN1
Antagonist of mitotic exit network protein 1

3

20

Small-scale

0.640

High

491832

HSP71
Heat shock protein SSA1

3

3

Small-scale

0.633

High

853199

CSN10
COP9 signalosome complex subunit 10

3

0

High-throughput

0.616

High

366595

HSP82
ATP-dependent molecular chaperone HSP82

2

4

Small-scale

0.601

High

566627

VATA
V-type proton ATPase catalytic subunit A

2

1

Small-scale

0.601

High

556164

VATB
V-type proton ATPase subunit B

2

0

Small-scale

0.585

High

494446

HSP72
Heat shock protein SSA2

2

3

Small-scale

0.584

High

544083

HSC82
ATP-dependent molecular chaperone HSC82

2

4

Small-scale

0.584

High

712963

BMH2
Protein BMH2

2

1

Small-scale

0.571

High

687432

EF2
Elongation factor 2

2

1

Small-scale

0.567

High

605454

VATE
V-type proton ATPase subunit E

2

0

Small-scale

0.563

High

696812

VATD
V-type proton ATPase subunit D

2

0

Small-scale

0.563

High

783848

BUB1
Checkpoint serine/threonine-protein kinase BUB1

1

2

Small-scale

0.561

High

775782

DSN1
Kinetochore-associated protein DSN1

2

0

Small-scale

0.559

High

814163

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

Small-scale

0.558

High

768926

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

812268

BIR1
Protein BIR1

2

0

Small-scale

0.551

High

752267

KIC1
Serine/threonine-protein kinase KIC1

1

1

High-throughput

0.536

High

853161

TDA1
Serine/threonine-protein kinase TDA1

1

3

High-throughput

0.536

High

593364

CG11
G1/S-specific cyclin CLN1

1

7

Small-scale

0.515

High

853200

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.515

High

728722

BDF1
Bromodomain-containing factor 1

1

2

High-throughput

0.508

High

688787

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

4

High-throughput

0.501

High

701904

SWE1
Mitosis inhibitor protein kinase SWE1

1

2

High-throughput

0.501

High

765176

PAC2
Protein PAC2

1

1

Small-scale

0.501

High

381618

GAL80
Galactose/lactose metabolism regulatory protein GAL80

1

0

Small-scale

0.493

High

774905

CSN11
Cop9 signalosome complex subunit 11

1

0

High-throughput

0.493

High

853166

CSN9
COP9 signalosome complex subunit 9

1

0

High-throughput

0.493

High

853184

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.486

High

614727

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

648212

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

853153

HST4
NAD-dependent histone deacetylase HST4

1

0

Small-scale

0.480

High

853190

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.480

High

485774

IF4A
ATP-dependent RNA helicase eIF4A

1

1

Small-scale

0.479

High

605370

HSP74
Heat shock protein SSA4

1

3

Small-scale

0.479

High

636677

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

664945

BMH1
Protein BMH1

1

1

Small-scale

0.479

High

698876

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

Small-scale

0.479

High

699011

GSP2
GTP-binding nuclear protein GSP2/CNR2

1

1

Small-scale

0.479

High

730016

RS27A
Small ribosomal subunit protein eS27A

1

1

Small-scale

0.479

High

763175

FHP
Flavohemoprotein

1

1

Small-scale

0.479

High

768393

GPP2
Glycerol-1-phosphate phosphohydrolase 2

1

1

Small-scale

0.479

High

783288

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

1

Small-scale

0.479

High

797479

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

853159

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

853169

YM13A
Transposon Ty1-MR1 Gag polyprotein

1

1

Small-scale

0.479

High

853202

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.479

High

853181

CORO
Coronin-like protein

1

4

High-throughput

0.464

High

586504

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.460

High

805181

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.460

High

811847

BFA1
Mitotic check point protein BFA1

1

0

Small-scale

0.460

High

853158

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.460

High

853168

LIC4
Protein ATC1/LIC4

1

0

High-throughput

0.460

High

853171

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

0

High-throughput

0.460

High

482355

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

546195

SYKC
Lysine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.458

High

560732

BIP
Endoplasmic reticulum chaperone BiP

1

0

Small-scale

0.458

High

628269

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

644923

RS5
Small ribosomal subunit protein uS7

1

0

Small-scale

0.458

High

662767

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

680860

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

686973

GLNA
Glutamine synthetase

1

0

High-throughput

0.458

High

692665

DUR1
Urea amidolyase [Includes: Urea carboxylase

1

0

Small-scale

0.458

High

693807

CBS
Cystathionine beta-synthase

1

0

Small-scale

0.458

High

730654

EF1G2
Elongation factor 1-gamma 2

1

0

Small-scale

0.458

High

741197

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

Small-scale

0.458

High

747744

SLI15
Inner centromere protein-related protein SLI15

1

0

Small-scale

0.458

High

748288

CENPU
Inner kinetochore subunit AME1

1

0

Small-scale

0.458

High

811739

YJ11B
Transposon Ty1-JR1 Gag-Pol polyprotein

1

0

Small-scale

0.458

High

853150

UFD1
Ubiquitin fusion degradation protein 1

1

0

High-throughput

0.458

High

853157

COFI
Cofilin

1

0

Small-scale

0.458

High

853160

SLD5
DNA replication complex GINS protein SLD5

1

0

Small-scale

0.458

High

853167

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

853170

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

853173

METX
Putative cystathionine gamma-synthase YML082W

1

0

High-throughput

0.458

High

853176

SWR1
Helicase SWR1

1

0

High-throughput

0.458

High

853180

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

853194

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

853196

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

450113

HSP73
Heat shock protein SSA3

1

3

High-throughput

0.445

High

675534

MCM4
DNA replication licensing factor MCM4

1

1

High-throughput

0.445

High

755699

DMA1
E3 ubiquitin-protein ligase DMA1

1

1

High-throughput

0.445

High

763432

MET10
Sulfite reductase [NADPH] flavoprotein component

1

1

High-throughput

0.445

High

853154

DMA2
E3 ubiquitin-protein ligase DMA2

1

1

High-throughput

0.445

High

387994

ADT1
ADP,ATP carrier protein 1

1

2

Small-scale

0.437

High

423031

TOM70
Mitochondrial import receptor subunit TOM70

1

1

Small-scale

0.437

High

546763

SEC23
Protein transport protein SEC23

1

1

Small-scale

0.437

High

575898

ADT3
ADP,ATP carrier protein 3

1

2

Small-scale

0.437

High

575987

ADT2
ADP,ATP carrier protein 2

1

2

Small-scale

0.437

High

732750

RL14A
Large ribosomal subunit protein eL14A

1

1

Small-scale

0.437

High

753018

RS27B
Small ribosomal subunit protein eS27B

1

1

Small-scale

0.437

High

753682

RL14B
Large ribosomal subunit protein eL14B

1

1

Small-scale

0.437

High

853193

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

1

Small-scale

0.437

High

853195

POM33
Pore membrane protein of 33 kDa

1

1

Small-scale

0.437

High

141861

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.426

High

478679

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.426

High

515197

SCH9
Serine/threonine-protein kinase SCH9

1

0

High-throughput

0.426

High

730859

CENPA
Histone H3-like centromeric protein CSE4

1

0

Small-scale

0.426

High

753075

OSH3
Oxysterol-binding protein homolog 3

1

0

High-throughput

0.426

High

761576

VATF
V-type proton ATPase subunit F

1

0

High-throughput

0.426

High

766113

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

784274

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.426

High

784955

MAF1
Repressor of RNA polymerase III transcription MAF1

1

0

High-throughput

0.426

High

853156

STP1
Transcription factor STP1

1

0

High-throughput

0.426

High

853185

CDC45
Cell division control protein 45

1

0

High-throughput

0.426

High

853201

YO098
Uncharacterized protein YOL098C

1

0

High-throughput

0.426

High

368749

GCN4
General control transcription factor GCN4

1

0

Small-scale

0.391

High

853179

BOP2
Protein BOP2

3

0

High-throughput

0.345

High

448508

PRTB
Cerevisin

2

0

High-throughput

0.313

High

853203

LAG2
Cullin-associated NEDD8-dissociated protein 1 homolog

1

0

Small-scale

0.301

High

748221

CS111
F-box protein COS111

1

0

High-throughput

0.279

Low

853186

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

745006

YB9Z
Inactive deaminase YBR284W

1

0

High-throughput

0.251

Low

342376

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.249

Low

343650

PMG1
Phosphoglycerate mutase 1

1

0

Small-scale

0.249

Low

450328

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.249

Low

480776

RS8A
Small ribosomal subunit protein eS8A

1

0

Small-scale

0.249

Low

521011

G6PI
Glucose-6-phosphate isomerase

1

0

Small-scale

0.249

Low

583241

METK2
S-adenosylmethionine synthase 2

1

0

Small-scale

0.249

Low

758003

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

762385

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

744108

ATG42
Vacuolar serine-type carboxypeptidase ATG42

1

0

High-throughput

0.232

Low

763753

YAE5
Putative uncharacterized protein YAL045C

1

0

High-throughput

0.232

Low

778781

FKS2
1,3-beta-glucan synthase component GSC2

1

0

High-throughput

0.232

Low

853151

TPN1
Vitamin B6 transporter TPN1

1

0

High-throughput

0.232

Low

853152

ARE2
Sterol O-acyltransferase 2

1

0

High-throughput

0.232

Low

853155

CACM
Putative mitochondrial carnitine O-acetyltransferase

1

0

High-throughput

0.232

Low

853162

YM30
Uncharacterized membrane protein YMR155W

1

0

High-throughput

0.232

Low

853192

YD172
Putative uncharacterized protein YDL172C

1

0

High-throughput

0.232

Low

853197

SUL2
Sulfate permease 2

1

0

Small-scale

0.232

Low

728426

YKF0
Uncharacterized protein YKL050C

1

0

Small-scale

0.213

Low


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Last updated: 15 Jul 2024