Protein: ADA2
Transcriptional adapter 2

Gene: ADA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 199
UniProt ID: Q02336

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0000183 - rDNA heterochromatin formation
GO:0000781 - chromosome, telomeric region
GO:0001786 - phosphatidylserine binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

970392

GCN5
Histone acetyltransferase GCN5

41

20

Small-scale

0.995

High

970385

ADA2
Transcriptional adapter 2

3

15

Small-scale

0.847

High

691338

NGG1
Chromatin-remodeling complexes subunit NGG1

32

3

Small-scale

0.769

High

715378

SPT7
Transcriptional activator SPT7

28

20

Small-scale

0.768

High

744672

TAF5
Transcription initiation factor TFIID subunit 5

20

16

Small-scale

0.764

High

755445

TRA1
Transcription-associated protein 1

17

7

Small-scale

0.764

High

858558

TAF6
Transcription initiation factor TFIID subunit 6

19

4

Small-scale

0.764

High

420619

SPT3
Protein SPT3

17

4

Small-scale

0.763

High

837453

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

17

9

Small-scale

0.763

High

970395

TAF12
Transcription initiation factor TFIID subunit 12

17

5

Small-scale

0.762

High

970414

HFI1
Transcriptional coactivator HFI1/ADA1

14

2

Small-scale

0.762

High

757456

SPT8
Transcription factor SPT8

14

1

Small-scale

0.761

High

859794

SGF73
SAGA-associated factor 73

14

5

Small-scale

0.761

High

970413

TAF10
Transcription initiation factor TFIID subunit 10

14

5

Small-scale

0.760

High

633891

SGF29
SAGA-associated factor 29

12

6

Small-scale

0.757

High

970403

TAF9
Transcription initiation factor TFIID subunit 9

10

8

Small-scale

0.753

High

970427

SUS1
Transcription and mRNA export factor SUS1

8

3

Small-scale

0.748

High

842071

SPT20
Transcription factor SPT20

18

0

Small-scale

0.732

High

970390

SGF11
SAGA-associated factor 11

9

0

Small-scale

0.717

High

805226

TAF1
Transcription initiation factor TFIID subunit 1

4

2

Small-scale

0.694

High

527042

TBP
TATA-box-binding protein

4

3

Small-scale

0.681

High

368754

GCN4
General control transcription factor GCN4

4

0

Small-scale

0.669

High

381567

GAL4
Regulatory protein GAL4

3

4

Small-scale

0.651

High

902005

H3
Histone H3

3

10

Small-scale

0.650

High

970422

AHC1
Protein AHC1

3

0

Small-scale

0.647

High

636027

AHC2
ADA histone acetyltransferase complex component 2

3

0

High-throughput

0.634

High

970410

MED7
Mediator of RNA polymerase II transcription subunit 7

2

3

High-throughput

0.621

High

697425

CHD1
Chromo domain-containing protein 1

1

14

Small-scale

0.618

High

716329

SPT10
Protein SPT10

1

2

High-throughput

0.618

High

492169

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.601

High

587880

AP1
AP-1-like transcription factor YAP1

2

1

High-throughput

0.601

High

693602

MED22
Mediator of RNA polymerase II transcription subunit 22

2

0

High-throughput

0.595

High

970408

THP1
Nuclear mRNA export protein THP1

2

0

Small-scale

0.585

High

687734

BTAF1
TATA-binding protein-associated factor MOT1

2

20

Small-scale

0.584

High

603004

BAS1
Myb-like DNA-binding protein BAS1

1

10

High-throughput

0.575

High

693055

RPD3
Histone deacetylase RPD3

1

4

High-throughput

0.575

High

375485

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

4

Small-scale

0.571

High

392184

H2A1
Histone H2A.1

2

7

Small-scale

0.571

High

692882

SPT16
FACT complex subunit SPT16

2

1

High-throughput

0.571

High

766819

SPC25
Kinetochore protein SPC25

2

0

High-throughput

0.570

High

761142

PCF11
Protein PCF11

2

0

High-throughput

0.565

High

805118

SAC3
Nuclear mRNA export protein SAC3

2

0

Small-scale

0.559

High

512401

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

334521

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.536

High

375625

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

4

High-throughput

0.536

High

636719

CDC48
Cell division control protein 48

1

1

High-throughput

0.536

High

665005

BMH1
Protein BMH1

1

4

High-throughput

0.536

High

676297

XPO1
Exportin-1

1

1

High-throughput

0.536

High

712989

BMH2
Protein BMH2

1

4

High-throughput

0.536

High

745429

RTG3
Retrograde regulation protein 3

1

1

High-throughput

0.536

High

970407

SUB2
ATP-dependent RNA helicase SUB2

1

2

High-throughput

0.536

High

970423

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.536

High

961903

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

5

Small-scale

0.529

High

409857

NOT2
General negative regulator of transcription subunit 2

1

1

Small-scale

0.518

High

530022

STE12
Protein STE12

1

0

High-throughput

0.513

High

608478

SAN1
Protein SAN1

1

0

High-throughput

0.513

High

730668

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.513

High

771731

PRS4
26S proteasome regulatory subunit 4 homolog

1

0

High-throughput

0.513

High

970391

TFB3
RNA polymerase II transcription factor B subunit 3

1

0

High-throughput

0.513

High

970420

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.513

High

655739

PRP45
Pre-mRNA-processing protein 45

1

3

High-throughput

0.508

High

688801

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

Small-scale

0.501

High

762066

IFH1
Protein IFH1

1

1

Small-scale

0.501

High

399918

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.489

High

478450

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.489

High

771349

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.486

High

809575

RRP41
Exosome complex component SKI6

1

0

High-throughput

0.486

High

811312

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.486

High

861186

BTN2
Protein BTN2

1

0

High-throughput

0.486

High

970388

ISU1
Iron sulfur cluster assembly protein 1, mitochondrial

1

0

High-throughput

0.486

High

970393

VPS71
Vacuolar protein sorting-associated protein 71

1

0

High-throughput

0.486

High

970399

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

0

High-throughput

0.486

High

970405

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.486

High

334783

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

Small-scale

0.479

High

416245

SIR2
NAD-dependent histone deacetylase SIR2

1

5

Small-scale

0.479

High

423701

ADR1
Regulatory protein ADR1

1

1

Small-scale

0.479

High

663077

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

688385

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

689939

ASF1
Histone chaperone ASF1

1

3

Small-scale

0.479

High

691106

HOG1
Mitogen-activated protein kinase HOG1

1

4

Small-scale

0.479

High

751071

RCK1
Serine/threonine-protein kinase RCK1

1

3

High-throughput

0.479

High

866414

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

970397

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

970401

POB3
FACT complex subunit POB3

1

2

High-throughput

0.479

High

970409

REXO4
RNA exonuclease 4

1

1

Small-scale

0.479

High

970412

CTI6
Histone deacetylase complex subunit CTI6

1

3

Small-scale

0.479

High

970416

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

700203

RT04
Small ribosomal subunit protein uS2m

1

2

High-throughput

0.464

High

753791

YHI2
Uncharacterized protein YHR022C

1

2

High-throughput

0.464

High

857406

VPS4
Vacuolar protein sorting-associated protein 4

1

2

High-throughput

0.464

High

970421

HSP42
Heat shock protein 42

1

1

High-throughput

0.464

High

141867

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.458

High

812083

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

970425

NOT5
General negative regulator of transcription subunit 5

1

0

Small-scale

0.458

High

355597

H2B1
Histone H2B.1

1

14

Small-scale

0.445

High

355981

H2B2
Histone H2B.2

1

14

Small-scale

0.445

High

392538

H2A2
Histone H2A.2

1

7

High-throughput

0.445

High

408442

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.445

High

419379

HAP2
Transcriptional activator HAP2

1

4

High-throughput

0.445

High

440085

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

3

High-throughput

0.445

High

450156

HSP73
Heat shock protein SSA3

1

5

High-throughput

0.445

High

472582

YL12B
Transposon Ty1-LR2 Gag-Pol polyprotein

1

2

High-throughput

0.445

High

554722

HSP26
Heat shock protein 26

1

1

High-throughput

0.445

High

560771

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

605254

AFT1
Iron-regulated transcriptional activator AFT1

1

2

High-throughput

0.445

High

609131

SIN3
Transcriptional regulatory protein SIN3

1

4

High-throughput

0.445

High

650370

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.445

High

706989

MSN2
Zinc finger protein MSN2

1

7

High-throughput

0.445

High

707047

MSN4
Zinc finger protein MSN4

1

6

High-throughput

0.445

High

733291

SET3
SET domain-containing protein 3

1

8

High-throughput

0.445

High

751472

MED31
Mediator of RNA polymerase II transcription subunit 31

1

3

High-throughput

0.445

High

766343

SNU13
13 kDa ribonucleoprotein-associated protein

1

1

High-throughput

0.445

High

767711

IMB4
Importin subunit beta-4

1

3

High-throughput

0.445

High

969403

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

20

High-throughput

0.445

High

970396

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.445

High

970402

RCO1
Transcriptional regulatory protein RCO1

1

14

High-throughput

0.445

High

970415

YG11B
Transposon Ty1-GR1 Gag-Pol polyprotein

1

2

High-throughput

0.445

High

970417

MAK21
Ribosome biogenesis protein MAK21

1

1

High-throughput

0.445

High

970418

HAL9
Halotolerance protein 9

1

4

High-throughput

0.445

High

970419

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.445

High

646640

DPB3
DNA polymerase epsilon subunit C

1

0

High-throughput

0.438

High

762485

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

333884

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

537472

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.426

High

549070

TRM1
tRNA

1

0

High-throughput

0.426

High

587322

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.426

High

747639

CCZ1
Vacuolar fusion protein CCZ1

1

0

High-throughput

0.426

High

763516

NUP60
Nucleoporin NUP60

1

0

High-throughput

0.426

High

777317

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.426

High

961996

REG1
Resistance to glucose repression protein 1

1

0

High-throughput

0.426

High

970389

DIG1
Down-regulator of invasive growth 1

1

0

High-throughput

0.426

High

970426

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.426

High

970411

SOG2
Leucine-rich repeat-containing protein SOG2

1

4

High-throughput

0.417

High

334974

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.407

High

357552

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.407

High

368333

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.407

High

399601

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

424672

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.407

High

485810

IF4A
ATP-dependent RNA helicase eIF4A

1

3

High-throughput

0.407

High

541909

NSP1
Nucleoporin NSP1

1

1

High-throughput

0.407

High

544272

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.407

High

561053

EF3A
Elongation factor 3A

1

1

High-throughput

0.407

High

566646

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.407

High

659978

MSP1
Outer mitochondrial transmembrane helix translocase

1

1

High-throughput

0.407

High

687464

EF2
Elongation factor 2

1

2

High-throughput

0.407

High

689374

ARP2
Actin-related protein 2

1

9

High-throughput

0.407

High

691582

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.407

High

715844

MDJ1
DnaJ homolog 1, mitochondrial

1

3

High-throughput

0.407

High

760936

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.407

High

765657

BEM2
GTPase-activating protein BEM2/IPL2

1

4

High-throughput

0.407

High

785172

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

859411

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

3

High-throughput

0.407

High

962619

ACAC
Acetyl-CoA carboxylase

1

2

High-throughput

0.407

High

970394

CLU
Clustered mitochondria protein 1

1

1

High-throughput

0.407

High

970400

RBA50
RNA polymerase II-associated protein RBA50

1

1

High-throughput

0.407

High

970424

NOP58
Nucleolar protein 58

1

2

High-throughput

0.407

High

811435

TCPQ
T-complex protein 1 subunit theta

2

0

High-throughput

0.313

High

360997

TBB
Tubulin beta chain

1

0

High-throughput

0.279

Low

416804

CDC31
Cell division control protein 31

1

0

Small-scale

0.279

Low

470763

RS21A
Small ribosomal subunit protein eS21A

1

0

High-throughput

0.279

Low

572056

CLC1
Clathrin light chain

1

0

High-throughput

0.279

Low

588201

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.279

Low

599870

DIT1
Spore wall maturation protein DIT1

1

0

High-throughput

0.279

Low

699807

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.279

Low

731007

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.279

Low

814713

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.279

Low

861330

TIM13
Mitochondrial import inner membrane translocase subunit TIM13

1

0

High-throughput

0.279

Low

630644

TRX3
Thioredoxin-3, mitochondrial

1

0

High-throughput

0.265

Low

763827

RBG1
Ribosome-interacting GTPase 1

1

0

High-throughput

0.265

Low

805316

AP3B
AP-3 complex subunit beta

1

0

High-throughput

0.265

Low

810802

BIT61
Target of rapamycin complex 2 subunit BIT61

1

0

High-throughput

0.265

Low

811591

MRX12
MIOREX complex component 12

1

0

High-throughput

0.265

Low

970386

YP077
Uncharacterized protein YPL077C

1

0

High-throughput

0.265

Low

970387

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

0

High-throughput

0.265

Low

294155

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.249

Low

481400

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

481976

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

784554

MID1
Stretch-activated cation channel MID1

1

0

Small-scale

0.249

Low

970398

GIS4
Protein GIS4

1

0

High-throughput

0.249

Low

970406

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

389976

VDAC1
Mitochondrial outer membrane protein porin 1

1

0

High-throughput

0.232

Low

399784

RLA1
Large ribosomal subunit protein P1A

1

0

High-throughput

0.232

Low

446214

MYO1
Myosin-1

1

0

High-throughput

0.232

Low

534828

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.232

Low

540143

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

562425

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.232

Low

568340

CAP
Adenylyl cyclase-associated protein

1

0

High-throughput

0.232

Low

614528

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

0

High-throughput

0.232

Low

629029

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low

677113

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.232

Low

704406

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.232

Low

713255

TSA1
Peroxiredoxin TSA1

1

0

High-throughput

0.232

Low

744063

SYG
Glycine--tRNA ligase 1, mitochondrial

1

0

High-throughput

0.232

Low

744110

ATG42
Vacuolar serine-type carboxypeptidase ATG42

1

0

High-throughput

0.232

Low

770025

YNU8
Uncharacterized protein YNL208W

1

0

High-throughput

0.232

Low

865712

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.232

Low

970404

NGK1
N-acetylglucosamine kinase

1

0

High-throughput

0.232

Low

970428

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024