Protein: ESA1
Histone acetyltransferase ESA1 (EC 2.3.1.48) (Protein 2-hydroxyisobutyryltransferase ESA1) (EC 2.3.1.-) (Protein acetyltransferase ESA1) (EC 2.3.1.-) (Protein crotonyltransferase ESA1) (EC 2.3.1.-)

Gene: ESA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 233
UniProt ID: Q08649

Gene Ontology (top 5):
GO:0000183 - rDNA heterochromatin formation
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0003682 - chromatin binding
GO:0003712 - transcription coregulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

797195

EPL1
Enhancer of polycomb-like protein 1

26

10

Small-scale

0.990

High

996188

EAF3
Chromatin modification-related protein EAF3

15

13

Small-scale

0.982

High

755379

YNG2
Chromatin modification-related protein YNG2

13

20

Small-scale

0.975

High

996173

ESA1
Histone acetyltransferase ESA1

4

14

Small-scale

0.868

High

755467

TRA1
Transcription-associated protein 1

19

12

Small-scale

0.764

High

987041

EAF1
Chromatin modification-related protein EAF1

16

1

Small-scale

0.761

High

946160

ARP4
Actin-related protein 4

16

20

Small-scale

0.761

High

866325

AF9
Protein AF-9 homolog

14

10

Small-scale

0.758

High

860110

SWC4
SWR1-complex protein 4

13

7

Small-scale

0.757

High

887703

ACT
Actin

14

13

Small-scale

0.757

High

356770

H4
Histone H4

10

13

Small-scale

0.755

High

812225

EAF6
Chromatin modification-related protein EAF6

11

1

Small-scale

0.751

High

866014

EAF7
Chromatin modification-related protein EAF7

7

1

Small-scale

0.744

High

392593

H2A2
Histone H2A.2

7

13

Small-scale

0.740

High

902113

H3
Histone H3

6

20

Small-scale

0.728

High

392220

H2A1
Histone H2A.1

6

13

Small-scale

0.726

High

766431

EAF5
Chromatin modification-related protein EAF5

11

0

Small-scale

0.722

High

355677

H2B1
Histone H2B.1

3

20

Small-scale

0.646

High

707063

MSN4
Zinc finger protein MSN4

3

5

Small-scale

0.641

High

587890

AP1
AP-1-like transcription factor YAP1

3

0

Small-scale

0.634

High

513017

SSB1
Ribosome-associated molecular chaperone SSB1

3

5

Small-scale

0.624

High

769673

SSB2
Ribosome-associated molecular chaperone SSB2

3

5

Small-scale

0.624

High

692953

SPT16
FACT complex subunit SPT16

2

1

Small-scale

0.585

High

695689

HSP7F
Heat shock protein homolog SSE1

2

10

Small-scale

0.585

High

996191

H2AZ
Histone H2A.Z

2

20

Small-scale

0.585

High

665092

BMH1
Protein BMH1

2

3

Small-scale

0.584

High

986192

NEJ1
Non-homologous end-joining protein 1

2

0

Small-scale

0.577

High

356037

H2B2
Histone H2B.2

2

20

Small-scale

0.571

High

961505

CDC14
Tyrosine-protein phosphatase CDC14

2

1

Small-scale

0.571

High

516328

RAP1
DNA-binding protein RAP1

1

0

Small-scale

0.561

High

728774

BDF1
Bromodomain-containing factor 1

2

20

Small-scale

0.552

High

784980

GLDS1
Protein GDS1

2

0

Small-scale

0.547

High

865547

CNM67
Chaotic nuclear migration protein 67

2

1

Small-scale

0.543

High

676438

XPO1
Exportin-1

1

2

High-throughput

0.536

High

760702

TCPB
T-complex protein 1 subunit beta

2

2

Small-scale

0.534

High

777328

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.513

High

539492

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

4

Small-scale

0.501

High

607353

RFA1
Replication factor A protein 1

1

2

Small-scale

0.501

High

627697

NAP1
Nucleosome assembly protein

1

7

Small-scale

0.501

High

634459

SPB1
27S pre-rRNA

1

2

Small-scale

0.501

High

681052

HS104
Heat shock protein 104

1

1

Small-scale

0.501

High

689976

ASF1
Histone chaperone ASF1

1

3

Small-scale

0.501

High

692368

PRP19
Pre-mRNA-processing factor 19

1

5

Small-scale

0.501

High

698188

AFG2
ATPase family gene 2 protein

1

1

Small-scale

0.501

High

703752

PRS6A
26S proteasome regulatory subunit 6A

1

1

Small-scale

0.501

High

758929

NAB3
Nuclear polyadenylated RNA-binding protein 3

1

1

Small-scale

0.501

High

777106

SYA
Alanine--tRNA ligase, mitochondrial

1

2

Small-scale

0.501

High

832206

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

1

Small-scale

0.501

High

837431

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

Small-scale

0.501

High

864149

HST2
NAD-dependent protein deacetylase HST2

1

5

Small-scale

0.501

High

864513

DBP6
ATP-dependent RNA helicase DBP6

1

6

Small-scale

0.501

High

865364

VPS75
Vacuolar protein sorting-associated protein 75

1

6

Small-scale

0.501

High

964878

CTF4
DNA polymerase alpha-binding protein

1

8

Small-scale

0.501

High

972665

SKI8
Antiviral protein SKI8

1

5

Small-scale

0.501

High

991242

BDF2
Bromodomain-containing factor 2

1

15

Small-scale

0.501

High

604242

APA2
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2

1

0

Small-scale

0.480

High

648338

GYS2
Glycogen [starch] synthase isoform 2

1

0

Small-scale

0.480

High

697328

GLRX4
Monothiol glutaredoxin-4

1

0

Small-scale

0.480

High

710321

SIP2
SNF1 protein kinase subunit beta-2

1

0

Small-scale

0.480

High

710407

EDE1
EH domain-containing and endocytosis protein 1

1

0

Small-scale

0.480

High

731558

POC2
Proteasome assembly chaperone 2

1

0

Small-scale

0.480

High

731936

ELF1
Transcription elongation factor 1

1

0

Small-scale

0.480

High

757364

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

Small-scale

0.480

High

766995

CHZ1
Histone H2A.Z-specific chaperone CHZ1

1

0

Small-scale

0.480

High

768151

MGDP1
Putative magnesium-dependent phosphatase YER134C

1

0

Small-scale

0.480

High

769977

IES2
Ino eighty subunit 2

1

0

Small-scale

0.480

High

838507

SOL1
6-phosphogluconolactonase-like protein 1

1

0

Small-scale

0.480

High

853190

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.480

High

860174

YG1B
Uncharacterized protein YGR017W

1

0

Small-scale

0.480

High

974216

UME1
Transcriptional regulatory protein UME1

1

0

Small-scale

0.480

High

983960

SVF1
Ceramide-binding protein SVF1

1

0

Small-scale

0.480

High

984966

EFM7
Protein N-terminal and lysine N-methyltransferase EFM7

1

0

Small-scale

0.480

High

987734

URN1
Pre-mRNA-splicing factor URN1

1

0

Small-scale

0.480

High

996177

CUB1

1

0

Small-scale

0.480

High

996178

PLP2
Phosducin-like protein 2

1

0

Small-scale

0.480

High

996185

HIF1
HAT1-interacting factor 1

1

0

Small-scale

0.480

High

996187

WHI5
G1-specific transcriptional repressor WHI5

1

0

Small-scale

0.480

High

376956

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

Small-scale

0.479

High

454487

TBA1
Tubulin alpha-1 chain

1

5

Small-scale

0.479

High

485600

SSBP1
Single-stranded nucleic acid-binding protein

1

5

Small-scale

0.479

High

593716

DBP4
ATP-dependent RNA helicase HCA4

1

4

Small-scale

0.479

High

619177

SPT6
Transcription elongation factor SPT6

1

2

Small-scale

0.479

High

650409

SPT5
Transcription elongation factor SPT5

1

1

Small-scale

0.479

High

687759

BTAF1
TATA-binding protein-associated factor MOT1

1

10

Small-scale

0.479

High

689302

SP110
Spindle pole body component 110

1

2

Small-scale

0.479

High

691135

HOG1
Mitogen-activated protein kinase HOG1

1

2

Small-scale

0.479

High

694287

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

High-throughput

0.479

High

696267

STH1
Nuclear protein STH1/NPS1

1

9

Small-scale

0.479

High

698697

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

1

Small-scale

0.479

High

703970

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

Small-scale

0.479

High

707001

MSN2
Zinc finger protein MSN2

1

6

Small-scale

0.479

High

713028

BMH2
Protein BMH2

1

3

Small-scale

0.479

High

728330

DEF1
RNA polymerase II degradation factor 1

1

1

Small-scale

0.479

High

742080

NOP4
Nucleolar protein 4

1

2

Small-scale

0.479

High

767752

IMB4
Importin subunit beta-4

1

4

Small-scale

0.479

High

797611

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

Small-scale

0.479

High

797967

RSC8
Chromatin structure-remodeling complex protein RSC8

1

1

Small-scale

0.479

High

972927

IMA1
Importin subunit alpha

1

8

Small-scale

0.479

High

977535

TAF12
Transcription initiation factor TFIID subunit 12

1

5

Small-scale

0.479

High

986148

IMB1
Importin subunit beta-1

1

4

Small-scale

0.479

High

987854

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

10

High-throughput

0.479

High

996176

NEW1
[NU+] prion formation protein 1

1

3

Small-scale

0.479

High

996181

SAS10
Something about silencing protein 10

1

1

Small-scale

0.479

High

859484

SLD3
DNA replication regulator SLD3

1

0

Small-scale

0.460

High

995650

SLD7
Mitochondrial morphogenesis protein SLD7

1

0

Small-scale

0.460

High

597274

PSA7
Probable proteasome subunit alpha type-7

1

0

Small-scale

0.458

High

663537

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

705965

SPC29
Spindle pole component 29

1

0

Small-scale

0.458

High

732524

SPC42
Spindle pole body component SPC42

1

0

Small-scale

0.458

High

753970

RPN1
26S proteasome regulatory subunit RPN1

1

0

Small-scale

0.458

High

755873

LSM12
Protein LSM12

1

0

Small-scale

0.458

High

759465

STM1
Suppressor protein STM1

1

0

Small-scale

0.458

High

771388

PSA4
Proteasome subunit alpha type-4

1

0

Small-scale

0.458

High

783567

HAC1
Transcriptional activator HAC1

1

0

Small-scale

0.458

High

797333

BLM10
Proteasome activator BLM10

1

0

Small-scale

0.458

High

810544

LSM1
Sm-like protein LSm1

1

0

Small-scale

0.458

High

861298

PBP1
PAB1-binding protein 1

1

0

Small-scale

0.458

High

976420

RPN4
Protein RPN4

1

0

Small-scale

0.458

High

978339

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

978618

SXM1
Importin beta SMX1

1

0

Small-scale

0.458

High

991182

PBP4
Protein PBP4

1

0

Small-scale

0.458

High

996179

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

996192

HAA1
Transcriptional activator HAA1

1

0

Small-scale

0.458

High

389019

SYTC
Threonine--tRNA ligase, cytoplasmic

1

1

Small-scale

0.457

High

417606

PHSG
Glycogen phosphorylase

1

1

Small-scale

0.457

High

564386

RL8A
Large ribosomal subunit protein eL8A

1

1

Small-scale

0.457

High

690283

CDC3
Cell division control protein 3

1

2

Small-scale

0.457

High

690348

CDC11
Cell division control protein 11

1

3

Small-scale

0.457

High

690564

CDC12
Cell division control protein 12

1

2

Small-scale

0.457

High

697611

HBS1
Elongation factor 1 alpha-like protein

1

1

Small-scale

0.457

High

699814

KPR1
Ribose-phosphate pyrophosphokinase 1

1

1

Small-scale

0.457

High

740820

ADCS
Aminodeoxychorismate synthase

1

1

Small-scale

0.457

High

753525

YLF2
Obg-like ATPase homolog

1

1

Small-scale

0.457

High

753552

OTU2
OTU domain-containing protein 2

1

1

Small-scale

0.457

High

859643

LSG1
Large subunit GTPase 1

1

2

Small-scale

0.457

High

974042

GDE1
Glycerophosphocholine phosphodiesterase GDE1

1

1

Small-scale

0.457

High

979438

TAP42
Type 2A phosphatase-associated protein 42

1

2

Small-scale

0.457

High

979739

UTP14
U3 small nucleolar RNA-associated protein 14

1

1

Small-scale

0.457

High

991730

SHS1
Seventh homolog of septin 1

1

5

Small-scale

0.457

High

994461

BRX1
Ribosome biogenesis protein BRX1

1

2

Small-scale

0.457

High

996180

CHS5
Chitin biosynthesis protein CHS5

1

1

Small-scale

0.457

High

996186

DBP10
ATP-dependent RNA helicase DBP10

1

4

Small-scale

0.457

High

367022

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

492677

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

495168

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

633650

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

697448

CHD1
Chromo domain-containing protein 1

1

6

High-throughput

0.445

High

754772

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

810404

JJJ2
J protein JJJ2

1

2

High-throughput

0.445

High

978031

RUVB1
RuvB-like protein 1

1

12

High-throughput

0.445

High

996189

RUVB2
RuvB-like protein 2

1

12

High-throughput

0.445

High

361063

TBB
Tubulin beta chain

1

2

Small-scale

0.437

High

416815

CDC31
Cell division control protein 31

1

1

Small-scale

0.437

High

472431

RL31A
Large ribosomal subunit protein eL31A

1

1

Small-scale

0.437

High

520005

TCPA
T-complex protein 1 subunit alpha

1

1

Small-scale

0.437

High

594434

SAR1
Small COPII coat GTPase SAR1

1

1

Small-scale

0.437

High

643032

BUB2
Mitotic check point protein BUB2

1

2

Small-scale

0.437

High

690985

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

1

Small-scale

0.437

High

696475

FIMB
Fimbrin

1

1

Small-scale

0.437

High

707948

GCN1
eIF-2-alpha kinase activator GCN1

1

2

Small-scale

0.437

High

710354

IF4B
Eukaryotic translation initiation factor 4B

1

1

Small-scale

0.437

High

746608

OLA1
Obg-like ATPase 1

1

1

Small-scale

0.437

High

760973

TCPD
T-complex protein 1 subunit delta

1

2

Small-scale

0.437

High

784362

COPB
Coatomer subunit beta

1

1

Small-scale

0.437

High

784442

COPB2
Coatomer subunit beta'

1

4

Small-scale

0.437

High

811484

TCPQ
T-complex protein 1 subunit theta

1

1

Small-scale

0.437

High

863649

COPA
Coatomer subunit alpha

1

4

Small-scale

0.437

High

866897

EF3B
Elongation factor 3B

1

3

Small-scale

0.437

High

979061

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.437

High

979666

SEC13
Protein transport protein SEC13

1

5

Small-scale

0.437

High

810743

NET1
Nucleolar protein NET1

1

0

High-throughput

0.426

High

862746

H1
Histone H1

1

0

High-throughput

0.426

High

629066

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

705751

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

715865

MDJ1
DnaJ homolog 1, mitochondrial

1

2

High-throughput

0.407

High

731157

LHS1
Heat shock protein 70 homolog LHS1

1

7

High-throughput

0.407

High

772941

TCPE
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.407

High

988599

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.407

High

772404

ATG3
Autophagy-related protein 3

2

0

Small-scale

0.328

High

333932

ADH1
Alcohol dehydrogenase 1

2

0

High-throughput

0.307

High

141951

YP089
Dilute domain-containing protein YPR089W

1

0

Small-scale

0.261

Low

425427

PIF1
ATP-dependent DNA helicase PIF1

1

0

Small-scale

0.261

Low

501302

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.261

Low

540199

NMT
Glycylpeptide N-tetradecanoyltransferase

1

0

Small-scale

0.261

Low

570728

HXKG
Glucokinase-1

1

0

Small-scale

0.261

Low

576120

MET16
Phosphoadenosine phosphosulfate reductase

1

0

Small-scale

0.261

Low

686906

P5CR
Pyrroline-5-carboxylate reductase

1

0

Small-scale

0.261

Low

688562

IMPX
Sugar utilization regulatory protein IMP2

1

0

Small-scale

0.261

Low

690374

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

1

0

Small-scale

0.261

Low

706172

MFT1
THO complex subunit MFT1

1

0

Small-scale

0.261

Low

743793

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

Small-scale

0.261

Low

747696

YSW1
Spore-specific protein YSW1

1

0

Small-scale

0.261

Low

770387

SIP5
Protein SIP5

1

0

Small-scale

0.261

Low

791287

KRI1
Protein KRI1

1

0

Small-scale

0.261

Low

859542

CUE3
RQC trigger complex subunit CUE3

1

0

Small-scale

0.261

Low

860085

EFM5
Protein-lysine N-methyltransferase EFM5

1

0

Small-scale

0.261

Low

860927

VOA1
V0 assembly protein 1

1

0

Small-scale

0.261

Low

865818

BNI5
Bud neck protein 5

1

0

Small-scale

0.261

Low

866346

APP1
Phosphatidate phosphatase APP1

1

0

Small-scale

0.261

Low

979385

YM54
Uncharacterized protein YMR196W

1

0

Small-scale

0.261

Low

984300

DON1
Donuts protein 1

1

0

Small-scale

0.261

Low

984754

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

Small-scale

0.261

Low

986129

YL345
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W [Includes: 6-phosphofructo-2-kinase

1

0

Small-scale

0.261

Low

986183

YL257
Uncharacterized protein YLR257W

1

0

Small-scale

0.261

Low

989237

MDM36
Mitochondrial distribution and morphology protein 36

1

0

Small-scale

0.261

Low

996150

AB140
tRNA(Thr)

1

0

Small-scale

0.261

Low

996174

MSC6
Meiotic sister-chromatid recombination protein 6, mitochondrial

1

0

Small-scale

0.261

Low

996175

SELO
Protein adenylyltransferase SelO, mitochondrial

1

0

Small-scale

0.261

Low

996182

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

0

Small-scale

0.261

Low

996190

ATG11
Autophagy-related protein 11

1

0

Small-scale

0.261

Low

420350

CALM
Calmodulin

1

0

Small-scale

0.249

Low

503029

SEC7
Protein transport protein SEC7

1

0

Small-scale

0.249

Low

503152

ARF1
ADP-ribosylation factor 1

1

0

Small-scale

0.249

Low

619645

MPCP
Mitochondrial phosphate carrier protein

1

0

Small-scale

0.249

Low

685580

COPG
Coatomer subunit gamma

1

0

Small-scale

0.249

Low

687898

NUD1
Protein NUD1

1

0

Small-scale

0.249

Low

700133

SKG6
Protein SKG6

1

0

Small-scale

0.249

Low

751430

FKS1
1,3-beta-glucan synthase component FKS1

1

0

Small-scale

0.249

Low

766894

RPN3
26S proteasome regulatory subunit RPN3

1

0

Small-scale

0.249

Low

774452

SEC24
Protein transport protein SEC24

1

0

Small-scale

0.249

Low

774870

COPE
Coatomer subunit epsilon

1

0

Small-scale

0.249

Low

804916

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

Small-scale

0.249

Low

811862

BFA1
Mitotic check point protein BFA1

1

0

Small-scale

0.249

Low

820213

RS12
Small ribosomal subunit protein eS12

1

0

Small-scale

0.249

Low

977175

CLU
Clustered mitochondria protein 1

1

0

Small-scale

0.249

Low

993923

MDM38
Mitochondrial distribution and morphology protein 38

1

0

Small-scale

0.249

Low

996183

PST1
Cell wall mannoprotein PST1

1

0

High-throughput

0.249

Low

996184

BBP1
Spindle pole component BBP1

1

0

Small-scale

0.249

Low

953550

YD271
Putative uncharacterized protein YDR271C

1

0

High-throughput

0.238

Low

368466

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

424752

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

979542

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024