Protein: FLP1
Tyrosine-protein phosphatase CDC14 homolog (EC 3.1.3.48) (CDC fourteen-like phosphatase 1)

Gene: FLP1, clp1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 140
UniProt ID: Q9P7H1

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000776 - kinetochore
GO:0000917 - division septum assembly
GO:0000922 - spindle pole
GO:0004721 - phosphoprotein phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

383476

CDK1
Cyclin-dependent kinase 1

2

4

Small-scale

0.778

High

840117

STE20
Serine/threonine-protein kinase shk1/pak1

1

1

High-throughput

0.724

High

788717

RAD24
Checkpoint signal transducer rad24

4

8

Small-scale

0.692

High

416125

MPIP
M-phase inducer phosphatase

4

3

Small-scale

0.683

High

737019

DSK1
Protein kinase dsk1

1

7

High-throughput

0.647

High

1265825

SPM1
Mitogen-activated protein kinase spm1

1

16

Small-scale

0.647

High

1350769

FLP1
Tyrosine-protein phosphatase CDC14 homolog

1

17

Small-scale

0.647

High

1185664

NSK1
Kinetochore protein nsk1

2

2

Small-scale

0.624

High

145511

IMDH
Inosine-5'-monophosphate dehydrogenase

1

2

High-throughput

0.618

High

223646

ARK1
Serine/threonine-protein kinase ark1

1

6

Small-scale

0.618

High

294180

BUB1
Checkpoint serine/threonine-protein kinase bub1

1

7

High-throughput

0.618

High

612381

KIN1
Protein kinase kin1

1

7

High-throughput

0.618

High

783445

RES2
Cell division cycle-related protein res2/pct1

1

17

High-throughput

0.618

High

998241

CDS1
Serine/threonine-protein kinase cds1

1

5

Small-scale

0.618

High

195139

MDE4
Monopolin complex subunit mde4

2

0

Small-scale

0.598

High

1093072

KLP9
Kinesin-like motor protein 9

2

11

Small-scale

0.595

High

945106

MID1
Anillin-related medial ring protein mid1

2

0

Small-scale

0.593

High

999946

CDC15
Cell division control protein 15

2

3

Small-scale

0.584

High

142463

PCS1
Monopolin complex subunit pcs1

2

0

Small-scale

0.576

High

195122

SEP1
Forkhead protein sep1

1

2

High-throughput

0.561

High

223579

KLP6
Kinesin-like protein 6

1

9

High-throughput

0.561

High

251570

CDC11
Septation initiation network scaffold protein cdc11

1

6

High-throughput

0.561

High

351028

CDC10
Start control protein cdc10

1

17

High-throughput

0.561

High

706682

RES1
Cell division cycle-related protein res1/sct1

1

18

High-throughput

0.561

High

1350779

PUB2
E3 ubiquitin-protein ligase pub2

1

13

Small-scale

0.561

High

1350780

DYLT
Dynein light chain Tctex-type

2

0

Small-scale

0.559

High

194837

NRM1
Transcription factor nrm1

1

0

High-throughput

0.537

High

777114

SAP1
Switch-activating protein 1

1

0

High-throughput

0.537

High

251338

DNT1
Nucleolar protein dnt1

1

1

Small-scale

0.508

High

1336797

ASE1
Anaphase spindle elongation protein 1

1

7

Small-scale

0.501

High

142793

CSX1
RNA-binding post-transcriptional regulator csx1

1

2

High-throughput

0.479

High

143247

DRI1
RNA-binding protein involved in heterochromatin assembly dri1

1

7

High-throughput

0.479

High

144033

OLA1
Obg-like ATPase 1

1

2

High-throughput

0.479

High

144261

BIR1
Protein bir1

1

3

High-throughput

0.479

High

144492

PRS6A
26S proteasome regulatory subunit 6A

1

8

High-throughput

0.479

High

144877

MYO3
Myosin type-2 heavy chain 2

1

7

High-throughput

0.479

High

144994

IQG1
Ras GTPase-activating-like protein rng2

1

7

High-throughput

0.479

High

145103

SFC1
Transcription factor tau subunit sfc1

1

1

High-throughput

0.479

High

145132

NOG2
Nucleolar GTP-binding protein 2

1

4

High-throughput

0.479

High

145332

YF19
Putative aldehyde dehydrogenase-like protein C9E9.09c

1

3

High-throughput

0.479

High

145380

YE8A
Probable inositol polyphosphate 5-phosphatase C9G1.10c

1

1

High-throughput

0.479

High

145505

KLP5
Kinesin-like protein 5

1

8

High-throughput

0.479

High

193887

YF82
GRIP and coiled-coil domain-containing protein C27D7.02c

1

6

High-throughput

0.479

High

194058

BUB3
Mitotic checkpoint protein bub3

1

7

High-throughput

0.479

High

195061

SRE2
Putative transcription factor sre2

1

2

High-throughput

0.479

High

251204

FKBP4
FK506-binding protein 39 kDa

1

5

High-throughput

0.479

High

251313

DCA13
Protein sof1

1

10

High-throughput

0.479

High

251409

YOCE
Uncharacterized RNA-binding protein C4F6.14

1

2

High-throughput

0.479

High

251467

UBP16
Probable ubiquitin carboxyl-terminal hydrolase 16

1

2

High-throughput

0.479

High

251494

SCW1
Cell wall integrity protein scw1

1

5

High-throughput

0.479

High

251500

STS5
Protein sts5

1

1

High-throughput

0.479

High

251517

SFC4
Transcription factor tau subunit sfc4

1

2

High-throughput

0.479

High

251535

YQC1
Uncharacterized protein C1739.01

1

2

High-throughput

0.479

High

251578

IMB3
Importin subunit beta-3

1

14

High-throughput

0.479

High

251751

POB1
Protein pob1

1

3

High-throughput

0.479

High

252129

RRP5
rRNA biogenesis protein rrp5

1

2

High-throughput

0.479

High

252624

YQL5
Uncharacterized RNA-binding protein C1827.05c

1

2

High-throughput

0.479

High

293465

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

293598

ALP14
Spindle pole body component alp14

1

13

High-throughput

0.479

High

294020

NSA1
Ribosome biogenesis protein nsa1

1

3

High-throughput

0.479

High

532291

PP11
Serine/threonine-protein phosphatase PP1-1

1

6

High-throughput

0.479

High

580775

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.479

High

737049

PMGY
Phosphoglycerate mutase

1

1

High-throughput

0.479

High

740392

DIS3
Exosome complex exonuclease dis3

1

1

High-throughput

0.479

High

772860

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.479

High

784717

PRS8
26S proteasome regulatory subunit 8 homolog

1

4

High-throughput

0.479

High

788731

RAD25
Checkpoint signal transducer rad25

1

7

High-throughput

0.479

High

953210

RPN1
26S proteasome regulatory subunit rpn1

1

4

High-throughput

0.479

High

968764

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.479

High

975929

PRH1
Probable ATP-dependent RNA helicase prh1

1

2

High-throughput

0.479

High

998274

MLR4
Myosin regulatory light chain cdc4

1

1

High-throughput

0.479

High

999808

RRP4
Exosome complex component rrp4

1

1

High-throughput

0.479

High

999850

YA4C
Arrestin domain-containing protein C31A2.12

1

2

High-throughput

0.479

High

999940

RENT1
ATP-dependent helicase upf1

1

3

High-throughput

0.479

High

1000087

HAS1
ATP-dependent RNA helicase has1

1

6

High-throughput

0.479

High

1013635

SYG
Putative glycine--tRNA ligase

1

1

High-throughput

0.479

High

1013724

GAF1
Transcription factor gaf1

1

2

High-throughput

0.479

High

1119780

SPC19
DASH complex subunit spc19

1

1

High-throughput

0.479

High

1303220

COPA
Putative coatomer subunit alpha

1

4

High-throughput

0.479

High

1319457

VPS5
Vacuolar protein sorting-associated protein vps5

1

5

High-throughput

0.479

High

1350700

RM09
Large ribosomal subunit protein uL3m

1

1

High-throughput

0.479

High

1350726

YN8E
Pumilio domain-containing protein P35G2.14

1

1

High-throughput

0.479

High

1350758

APP1
Protein app1

1

12

High-throughput

0.479

High

1350771

DNA2
DNA replication ATP-dependent helicase/nuclease dna2 [Includes: DNA replication nuclease dna2

1

3

High-throughput

0.479

High

1350773

CLC1
Clathrin light chain

1

4

High-throughput

0.479

High

1350776

MRT4
Ribosome assembly factor mrt4

1

2

High-throughput

0.479

High

1350777

2AAA
Protein phosphatase PP2A regulatory subunit A

1

9

Small-scale

0.479

High

1350778

RL1DB
Putative ribosome biogenesis protein C8F11.04

1

2

High-throughput

0.479

High

1350782

AP1G1
AP-1 complex subunit gamma-1

1

7

High-throughput

0.479

High

1350784

RGF3
Rho1 guanine nucleotide exchange factor 3

1

3

High-throughput

0.479

High

1350785

MYO1
Myosin-1

1

12

High-throughput

0.479

High

142250

SFC9
Putative transcription factor tau subunit sfc9

1

0

High-throughput

0.458

High

142612

MUG61
Meiotically up-regulated gene 61 protein

1

0

High-throughput

0.458

High

142722

NOP12
Nucleolar protein 12

1

0

High-throughput

0.458

High

144224

PNO1
Pre-rRNA-processing protein pno1

1

0

High-throughput

0.458

High

145374

CYK3
cytokinesis protein 3

1

0

High-throughput

0.458

High

195077

RGA6
Probable Rho-GTPase-activating protein 6

1

0

High-throughput

0.458

High

223973

BAG1A
BAG family molecular chaperone regulator 1A

1

0

High-throughput

0.458

High

251308

BLT1
Mitosis inducer protein blt1

1

0

High-throughput

0.458

High

251424

YJL4
Uncharacterized protein C14G10.04

1

0

High-throughput

0.458

High

251449

MU174
Meiotically up-regulated gene 174 protein

1

0

High-throughput

0.458

High

251574

FKS4
1,3-beta-glucan synthase component bgs4

1

0

High-throughput

0.458

High

251921

MU164
Microtubule-associated protein mug164

1

0

High-throughput

0.458

High

293149

MU118
Meiotically up-regulated gene 118 protein

1

0

High-throughput

0.458

High

293946

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

777424

YOX1
MBF complex negative regulatory component yox1

1

0

High-throughput

0.458

High

945029

UGPA1
Probable UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.458

High

953327

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.458

High

997981

RNP24
RNA-binding protein rnp24

1

0

High-throughput

0.458

High

999749

LYS1
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]

1

0

High-throughput

0.458

High

999933

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.458

High

1013747

YD4B
Uncharacterized protein C22H10.11c

1

0

High-throughput

0.458

High

1093064

PIC1
Inner centromere protein-related protein pic1

1

0

High-throughput

0.458

High

1303225

YNH5
UPF0642 protein C32H8.05

1

0

High-throughput

0.458

High

1350772

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.458

High

1350774

SFC3
Transcription factor tau subunit sfc3

1

0

High-throughput

0.458

High

1350775

ATH1
Ataxin-2 homolog

1

0

High-throughput

0.458

High

1350781

NSA2
Ribosome biogenesis protein nsa2

1

0

High-throughput

0.458

High

1350783

PAL1
Protein pal1

1

0

High-throughput

0.458

High

142032

SAHH
Adenosylhomocysteinase

1

8

High-throughput

0.437

High

144272

ATC4
Endoplasmic reticulum transmembrane helix translocase

1

6

High-throughput

0.437

High

194917

YBP8
Uncharacterized ABC transporter ATP-binding protein C16H5.08c

1

3

High-throughput

0.437

High

195033

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

2

High-throughput

0.437

High

224200

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.437

High

251430

ENT1
Epsin-1

1

2

High-throughput

0.437

High

251456

YJE9
Uncharacterized mitochondrial carrier C1682.09c

1

4

High-throughput

0.437

High

293536

YN67
Putative enoyl reductase C646.07c

1

2

High-throughput

0.437

High

603272

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.437

High

736838

ARF1
ADP-ribosylation factor 1

1

1

High-throughput

0.437

High

1013477

GCN1
eIF-2-alpha kinase activator gcn1

1

20

High-throughput

0.437

High

1350770

MPCP
Probable mitochondrial phosphate carrier protein

1

4

High-throughput

0.437

High

194948

MBX1
MADS-box transcription factor 1

2

0

Small-scale

0.333

High

143449

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

Small-scale

0.251

Low

143421

SEL1
Eisosome protein sle1

1

0

High-throughput

0.249

Low

251651

PROD
Probable proline dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

408520

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.249

Low

772829

MAOX
NAD-dependent malic enzyme

1

0

High-throughput

0.249

Low

953492

CUE4
CUE domain-containing protein 4, mitochondrial

1

0

High-throughput

0.249

Low

1265770

PFL8
Putative cell agglutination protein pfl8

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024