Protein: RLA4
Large ribosomal subunit protein P2B (P2B) (60S acidic ribosomal protein P2-beta) (L12eIA) (L45) (YL44C) (YP2beta) (YPA1)

Gene: RLA4, RPP2B
Organism: Saccharomyces cerevisiae S288C
Interactions: 188
UniProt ID: P02400

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0002181 - cytoplasmic translation
GO:0002182 - cytoplasmic translational elongation
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

357410

RLA1
Large ribosomal subunit protein P1A

8

8

Small-scale

0.961

High

357409

RLA0
Large ribosomal subunit protein uL10

5

3

Small-scale

0.916

High

357411

RLA2
Large ribosomal subunit protein P2A

5

4

Small-scale

0.904

High

357442

RLA3
Large ribosomal subunit protein P1B

5

8

Small-scale

0.901

High

357402

RLA4
Large ribosomal subunit protein P2B

2

4

Small-scale

0.743

High

357404

HSP82
ATP-dependent molecular chaperone HSP82

3

3

High-throughput

0.640

High

357559

GCN5
Histone acetyltransferase GCN5

2

1

High-throughput

0.628

High

357541

BRE5
UBP3-associated protein BRE5

2

3

High-throughput

0.611

High

357466

RL16A
Large ribosomal subunit protein uL13A

2

4

High-throughput

0.584

High

357574

TMA46
Translation machinery-associated protein 46

2

2

High-throughput

0.584

High

357449

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.571

High

357543

JJJ1
J protein JJJ1

2

6

High-throughput

0.571

High

357463

PWP2
Periodic tryptophan protein 2

2

1

High-throughput

0.567

High

357499

SEC31
Protein transport protein SEC31

2

2

High-throughput

0.567

High

357578

MAK21
Ribosome biogenesis protein MAK21

2

1

High-throughput

0.567

High

357568

RQC1
Ribosome quality control complex subunit 1

2

1

Small-scale

0.558

High

357492

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

2

1

High-throughput

0.537

High

357531

TAF6
Transcription initiation factor TFIID subunit 6

1

1

High-throughput

0.536

High

357536

SGF73
SAGA-associated factor 73

1

1

High-throughput

0.536

High

357550

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

4

High-throughput

0.536

High

357422

KAPC
cAMP-dependent protein kinase type 3

1

1

High-throughput

0.501

High

357424

KIN28
Serine/threonine-protein kinase KIN28

1

2

High-throughput

0.501

High

357450

CSK21
Casein kinase II subunit alpha

1

4

Small-scale

0.501

High

357454

CSK22
Casein kinase II subunit alpha'

1

2

Small-scale

0.501

High

357521

IKS1
Probable serine/threonine-protein kinase IKS1

1

4

High-throughput

0.501

High

357479

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

1

High-throughput

0.494

High

357426

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.489

High

357460

SGF29
SAGA-associated factor 29

1

1

High-throughput

0.489

High

357483

SPT7
Transcriptional activator SPT7

1

3

High-throughput

0.489

High

357490

TAF5
Transcription initiation factor TFIID subunit 5

1

4

High-throughput

0.489

High

357529

SPT20
Transcription factor SPT20

1

1

High-throughput

0.489

High

357560

TAF12
Transcription initiation factor TFIID subunit 12

1

1

High-throughput

0.489

High

357567

TAF9
Transcription initiation factor TFIID subunit 9

1

1

High-throughput

0.489

High

357586

SUS1
Transcription and mRNA export factor SUS1

1

2

High-throughput

0.489

High

357489

UGA2
Succinate-semialdehyde dehydrogenase [NADP(+)]

1

0

High-throughput

0.486

High

145653

RL36B
Large ribosomal subunit protein eL36B

1

4

High-throughput

0.479

High

357403

RL28
Large ribosomal subunit protein uL15

1

1

High-throughput

0.479

High

357406

RL24A
Large ribosomal subunit protein eL24A

1

3

High-throughput

0.479

High

357407

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

357408

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.479

High

357412

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.479

High

357413

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.479

High

357414

RL6B
Large ribosomal subunit protein eL6B

1

3

High-throughput

0.479

High

357415

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.479

High

357416

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.479

High

357417

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

357418

RL36A
Large ribosomal subunit protein eL36A

1

4

High-throughput

0.479

High

357420

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

357421

RL22A
Large ribosomal subunit protein eL22A

1

3

High-throughput

0.479

High

357425

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

3

High-throughput

0.479

High

357427

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

3

High-throughput

0.479

High

357428

RL11A
Large ribosomal subunit protein uL5A

1

3

High-throughput

0.479

High

357429

RL27A
Large ribosomal subunit protein eL27A

1

2

High-throughput

0.479

High

357430

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.479

High

357431

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

357432

RL31B
Large ribosomal subunit protein eL31B

1

2

High-throughput

0.479

High

357433

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.479

High

357434

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.479

High

357436

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

357437

RL2A
Large ribosomal subunit protein uL2A

1

2

High-throughput

0.479

High

357440

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

357441

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.479

High

357443

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.479

High

357444

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.479

High

357445

PDR1
Transcription factor PDR1

1

1

High-throughput

0.479

High

357447

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.479

High

357448

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

357452

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.479

High

357455

RAD53
Serine/threonine-protein kinase RAD53

1

3

High-throughput

0.479

High

357456

RL24B
Large ribosomal subunit protein eL24B

1

3

High-throughput

0.479

High

357458

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

357465

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

357467

RL16B
Large ribosomal subunit protein uL13B

1

4

High-throughput

0.479

High

357472

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.479

High

357473

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

357476

ZUO1
Zuotin

1

4

High-throughput

0.479

High

357480

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

357485

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.479

High

357488

RL32
Large ribosomal subunit protein eL32

1

3

High-throughput

0.479

High

357491

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

3

High-throughput

0.479

High

357494

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.479

High

357496

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.479

High

357501

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

357503

RBG1
Ribosome-interacting GTPase 1

1

2

High-throughput

0.479

High

357504

IF2P
Eukaryotic translation initiation factor 5B

1

2

High-throughput

0.479

High

357508

RL13B
Large ribosomal subunit protein eL13B

1

3

High-throughput

0.479

High

357513

RL34B
Large ribosomal subunit protein eL34B

1

3

High-throughput

0.479

High

357515

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.479

High

357516

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

357519

RL17B
Large ribosomal subunit protein uL22B

1

3

High-throughput

0.479

High

357524

RL37A
Large ribosomal subunit protein eL37A

1

3

High-throughput

0.479

High

357525

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

357526

RL4B
Large ribosomal subunit protein uL4B

1

3

High-throughput

0.479

High

357530

RL37B
Large ribosomal subunit protein eL37B

1

3

High-throughput

0.479

High

357537

RL26B
Large ribosomal subunit protein uL24B

1

3

High-throughput

0.479

High

357547

RL22B
Large ribosomal subunit protein eL22B

1

3

High-throughput

0.479

High

357549

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

357551

RL6A
Large ribosomal subunit protein eL6A

1

3

High-throughput

0.479

High

357555

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

357561

HMO1
High mobility group protein 1

1

4

High-throughput

0.479

High

357566

LTN1
E3 ubiquitin-protein ligase listerin

1

1

Small-scale

0.479

High

357579

RL7B
Large ribosomal subunit protein uL30B

1

4

High-throughput

0.479

High

357582

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

357583

RL13A
Large ribosomal subunit protein eL13A

1

3

High-throughput

0.479

High

357585

RL11B
Large ribosomal subunit protein uL5B

1

3

High-throughput

0.479

High

357419

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

357435

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.458

High

357438

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.458

High

357439

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.458

High

357507

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.458

High

357532

DXO
Decapping nuclease RAI1

1

0

High-throughput

0.458

High

357535

LSG1
Large subunit GTPase 1

1

0

High-throughput

0.458

High

357571

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

357576

CHS5
Chitin biosynthesis protein CHS5

1

0

High-throughput

0.458

High

357459

KCC4
Probable serine/threonine-protein kinase KCC4

1

2

High-throughput

0.457

High

357468

CDC15
Cell division control protein 15

1

2

High-throughput

0.457

High

357580

PKH2
Serine/threonine-protein kinase PKH2

1

2

High-throughput

0.457

High

357477

RPD3
Histone deacetylase RPD3

1

3

Small-scale

0.457

High

357534

SNT2
E3 ubiquitin-protein ligase SNT2

1

1

Small-scale

0.457

High

357514

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.439

High

357554

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.439

High

339308

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.437

High

357423

SC160
Protein SCP160

1

2

High-throughput

0.437

High

357446

ACOX
Acyl-coenzyme A oxidase

1

2

High-throughput

0.437

High

357451

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

357457

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.437

High

357461

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

357462

SYP1
Suppressor of yeast profilin deletion

1

1

High-throughput

0.437

High

357464

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

357469

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

357470

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

357482

IXR1
Intrastrand cross-link recognition protein

1

4

Small-scale

0.437

High

357486

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.437

High

357487

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

357493

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.437

High

357500

STM1
Suppressor protein STM1

1

1

High-throughput

0.437

High

357502

ECM1
Shuttling pre-60S factor ECM1

1

1

High-throughput

0.437

High

357505

NOC2
Nucleolar complex protein 2

1

1

Small-scale

0.437

High

357511

TM108
Protein TMA108

1

1

High-throughput

0.437

High

357517

ELP2
Elongator complex protein 2

1

3

High-throughput

0.437

High

357518

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

357522

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

357523

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

357527

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.437

High

357533

VID30
Vacuolar import and degradation protein 30

1

1

High-throughput

0.437

High

357538

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

357539

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.437

High

357540

H1
Histone H1

1

1

High-throughput

0.437

High

357542

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

357544

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.437

High

357546

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.437

High

357553

ABF2
ARS-binding factor 2, mitochondrial

1

4

High-throughput

0.437

High

357558

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.437

High

357562

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.437

High

357564

UTP14
U3 small nucleolar RNA-associated protein 14

1

1

High-throughput

0.437

High

357570

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

357573

SGO1
Shugoshin

1

1

High-throughput

0.437

High

357581

RQC2
Ribosome quality control complex subunit 2

1

1

High-throughput

0.437

High

357584

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.437

High

357528

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

2

High-throughput

0.407

High

357552

ADA2
Transcriptional adapter 2

1

1

High-throughput

0.407

High

357575

HFI1
Transcriptional coactivator HFI1/ADA1

1

1

High-throughput

0.407

High

357453

SKI3
Superkiller protein 3

1

0

High-throughput

0.279

Low

357563

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.279

Low

357405

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

357471

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

357474

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.249

Low

357475

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

357478

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.249

Low

357484

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.249

Low

357495

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

357497

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.249

Low

357498

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.249

Low

357506

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

0

High-throughput

0.249

Low

357510

YIQ1
Uncharacterized protein YIL161W

1

0

High-throughput

0.249

Low

357545

FAP1
FKBP12-associated protein 1

1

0

High-throughput

0.249

Low

357556

ELP3
Elongator complex protein 3

1

0

High-throughput

0.249

Low

357557

ESP1
Separin

1

0

High-throughput

0.249

Low

357565

VBA4
Vacuolar basic amino acid transporter 4

1

0

High-throughput

0.249

Low

357569

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

0

High-throughput

0.249

Low

357572

NOP6
Nucleolar protein 6

1

0

High-throughput

0.249

Low

357577

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.249

Low

357520

MRX5
MIOREX complex component 5

1

0

High-throughput

0.238

Low

357548

ACT
Actin

1

0

Small-scale

0.238

Low

357481

YME2
Mitochondrial escape protein 2

1

0

High-throughput

0.232

Low

357509

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.232

Low

357512

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024