Protein: ERF1
Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Omnipotent suppressor protein 1)

Gene: ERF1, SUP45
Organism: Saccharomyces cerevisiae S288C
Interactions: 128
UniProt ID: P12385

Gene Ontology (top 5):
GO:0002184 - cytoplasmic translational termination
GO:0003747 - translation release factor activity
GO:0004045 - aminoacyl-tRNA hydrolase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

402857

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

19

3

Small-scale

0.989

High

519623

RLI1
Translation initiation factor RLI1

3

3

Small-scale

0.864

High

490152

HSP71
Heat shock protein SSA1

3

2

High-throughput

0.624

High

493040

HSP72
Heat shock protein SSA2

3

2

High-throughput

0.624

High

519619

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

2

High-throughput

0.601

High

519587

ECM29
Proteasome component ECM29

2

1

High-throughput

0.588

High

519598

IMB4
Importin subunit beta-4

2

1

High-throughput

0.588

High

519570

RENT1
ATP-dependent helicase NAM7

2

2

Small-scale

0.586

High

519568

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.585

High

519562

SIS1
Protein SIS1

2

2

High-throughput

0.584

High

519605

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

367665

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.575

High

365676

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.571

High

519566

MAS5
Mitochondrial protein import protein MAS5

2

1

High-throughput

0.571

High

519573

HSP7F
Heat shock protein homolog SSE1

2

3

High-throughput

0.571

High

519626

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

2

0

Small-scale

0.569

High

519583

ATR
Serine/threonine-protein kinase MEC1

2

1

High-throughput

0.567

High

450381

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

2

0

High-throughput

0.563

High

519579

UTP20
U3 small nucleolar RNA-associated protein 20

2

0

High-throughput

0.563

High

519584

EIF3A
Eukaryotic translation initiation factor 3 subunit A

2

0

High-throughput

0.563

High

519607

YJB6
Uncharacterized protein YJL016W

2

0

High-throughput

0.563

High

519625

CLU
Clustered mitochondria protein 1

2

0

High-throughput

0.563

High

406718

RS3
Small ribosomal subunit protein uS3

2

0

Small-scale

0.559

High

519558

DBP5
ATP-dependent RNA helicase DBP5

2

0

Small-scale

0.559

High

519582

GBLP
Small ribosomal subunit protein RACK1

2

0

Small-scale

0.559

High

519644

GLE1
mRNA export factor GLE1

1

0

Small-scale

0.554

High

382908

RL25
Large ribosomal subunit protein uL23

2

0

Small-scale

0.547

High

479673

RS4A
Small ribosomal subunit protein eS4A

2

0

Small-scale

0.547

High

519559

RPA2
DNA-directed RNA polymerase I subunit RPA135

2

2

High-throughput

0.537

High

145691

RL36B
Large ribosomal subunit protein eL36B

1

0

High-throughput

0.513

High

420539

SPT2
Protein SPT2

1

0

High-throughput

0.513

High

519580

OSH1
Oxysterol-binding protein homolog 1

1

0

High-throughput

0.513

High

519585

SHE3
SWI5-dependent HO expression protein 3

1

0

High-throughput

0.513

High

519611

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.513

High

519629

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

Small-scale

0.501

High

519631

ITT1
E3 ubiquitin-protein ligase ITT1

1

2

Small-scale

0.501

High

519555

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.493

High

519601

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

Small-scale

0.480

High

357837

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

485620

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.479

High

519554

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

519571

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.479

High

519574

ECM32
Putative ATP-dependent RNA helicase ECM32

1

2

Small-scale

0.479

High

519616

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

High-throughput

0.479

High

519624

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

342633

ENO1
Enolase 1

1

0

High-throughput

0.458

High

407676

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

410286

SC160
Protein SCP160

1

0

High-throughput

0.458

High

425713

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

470812

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

471976

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

479876

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

498413

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.458

High

519550

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

519560

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

519563

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.458

High

519565

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

519567

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

519575

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

519576

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

519577

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

519581

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

519586

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

519590

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

519592

ASPG1
L-asparaginase 1

1

0

High-throughput

0.458

High

519594

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

519597

TPA1
Prolyl 3,4-dihydroxylase TPA1

1

0

Small-scale

0.458

High

519602

TM108
Protein TMA108

1

0

High-throughput

0.458

High

519608

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

519614

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.458

High

519615

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

519620

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

519622

ESP1
Separin

1

0

High-throughput

0.458

High

519628

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

519630

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

519632

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

519633

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

Small-scale

0.458

High

519638

SUB2
ATP-dependent RNA helicase SUB2

1

0

High-throughput

0.458

High

519639

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

519640

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

519642

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

519643

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

519646

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

376603

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

Small-scale

0.445

High

404475

RL7A
Large ribosomal subunit protein uL30A

1

1

Small-scale

0.445

High

510060

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

519552

RS17B
Small ribosomal subunit protein eS17B

1

1

High-throughput

0.445

High

519572

ZUO1
Zuotin

1

2

High-throughput

0.445

High

519589

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

519596

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

519599

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

519561

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.437

High

519604

RLP7
Ribosome biogenesis protein RLP7

1

1

High-throughput

0.437

High

519627

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

519645

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

339986

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

415873

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.426

High

424306

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

424804

IF4E
Eukaryotic translation initiation factor 4E

1

0

Small-scale

0.426

High

498766

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.426

High

519551

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.426

High

519553

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

519593

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

519595

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.426

High

519600

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.426

High

519606

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

519564

USO1
Intracellular protein transport protein USO1

2

0

High-throughput

0.324

High

519603

TAO3
Cell morphogenesis protein PAG1

2

0

High-throughput

0.324

High

519610

ROM2
RHO1 GDP-GTP exchange protein 2

2

0

High-throughput

0.324

High

519621

SEN54
tRNA-splicing endonuclease subunit SEN54

2

0

High-throughput

0.324

High

519636

CORO
Coronin-like protein

2

0

High-throughput

0.324

High

519637

VAC14
Vacuole morphology and inheritance protein 14

2

0

High-throughput

0.324

High

519609

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.279

Low

474314

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

519556

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

519557

HEMH
Ferrochelatase, mitochondrial

1

0

Small-scale

0.249

Low

519569

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

519588

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.249

Low

519612

MLC1
Myosin light chain 1

1

0

Small-scale

0.249

Low

519613

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

519617

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

519618

H3
Histone H3

1

0

High-throughput

0.249

Low

519634

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

519635

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

519641

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

519578

SPT7
Transcriptional activator SPT7

1

0

High-throughput

0.232

Low

519591

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low

519647

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024