Protein: NOP15
Ribosome biogenesis protein 15 (Nucleolar protein 15)

Gene: NOP15
Organism: Saccharomyces cerevisiae S288C
Interactions: 191
UniProt ID: P53927

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

742044

NOP4
Nucleolar protein 4

4

19

High-throughput

0.892

High

866243

NOP15
Ribosome biogenesis protein 15

4

15

Small-scale

0.878

High

865735

NOP13
Nucleolar protein 13

3

20

High-throughput

0.847

High

383283

RL25
Large ribosomal subunit protein uL23

2

3

Small-scale

0.754

High

866277

NOP12
Nucleolar protein 12

2

18

High-throughput

0.754

High

866255

HAS1
ATP-dependent RNA helicase HAS1

9

20

High-throughput

0.751

High

860853

PESC
Pescadillo homolog

9

1

Small-scale

0.751

High

754162

CIC1
Proteasome-interacting protein CIC1

8

3

Small-scale

0.750

High

733890

RPF2
Ribosome biogenesis protein RPF2

8

1

Small-scale

0.748

High

766678

NUG1
Nuclear GTP-binding protein NUG1

7

7

High-throughput

0.744

High

866252

NOG1
Nucleolar GTP-binding protein 1

7

4

Small-scale

0.744

High

638830

SPB4
ATP-dependent rRNA helicase SPB4

7

18

High-throughput

0.740

High

776481

RLP7
Ribosome biogenesis protein RLP7

6

5

Small-scale

0.737

High

768031

NSA2
Ribosome biogenesis protein NSA2

6

2

High-throughput

0.730

High

859490

NSA1
Ribosome biogenesis protein NSA1

6

1

Small-scale

0.729

High

764218

NOC2
Nucleolar complex protein 2

6

3

Small-scale

0.726

High

866262

ERB1
Ribosome biogenesis protein ERB1

5

10

High-throughput

0.716

High

866284

YTM1
Ribosome biogenesis protein YTM1

5

20

High-throughput

0.712

High

866290

DBP10
ATP-dependent RNA helicase DBP10

5

19

High-throughput

0.712

High

755312

RPF1
Ribosome production factor 1

5

2

High-throughput

0.712

High

434771

PBS2
MAP kinase kinase PBS2

1

12

High-throughput

0.691

High

602731

MCK1
Protein kinase MCK1

1

9

High-throughput

0.691

High

634431

SPB1
27S pre-rRNA

4

7

High-throughput

0.691

High

699710

DRS1
ATP-dependent RNA helicase DRS1

4

20

High-throughput

0.691

High

865659

IPI3
Pre-rRNA-processing protein IPI3

4

8

High-throughput

0.691

High

866278

BRX1
Ribosome biogenesis protein BRX1

4

9

High-throughput

0.691

High

866283

MDN1
Midasin

4

2

High-throughput

0.691

High

866288

MAK21
Ribosome biogenesis protein MAK21

4

5

High-throughput

0.691

High

756851

RIX1
Pre-rRNA-processing protein RIX1

5

0

Small-scale

0.686

High

866286

NOP53
Ribosome biogenesis protein NOP53

4

2

High-throughput

0.683

High

778831

NOP2
25S rRNA

4

2

Small-scale

0.676

High

864658

NOG2
Nucleolar GTP-binding protein 2

4

7

Small-scale

0.676

High

859400

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

3

High-throughput

0.670

High

866294

IF6
Eukaryotic translation initiation factor 6

4

0

High-throughput

0.664

High

715963

UTP20
U3 small nucleolar RNA-associated protein 20

3

1

High-throughput

0.662

High

861394

SDA1
Protein SDA1

3

1

High-throughput

0.662

High

866256

ARX1
Probable metalloprotease ARX1

3

3

High-throughput

0.662

High

866273

RIX7
Ribosome biogenesis ATPase RIX7

3

8

High-throughput

0.662

High

866296

RRP12
Ribosomal RNA-processing protein 12

3

1

High-throughput

0.662

High

731844

EBP2
rRNA-processing protein EBP2

3

1

High-throughput

0.650

High

866267

JIP5
WD repeat-containing protein JIP5

3

11

High-throughput

0.650

High

866281

RRS1
Regulator of ribosome biosynthesis

3

2

High-throughput

0.650

High

866257

RRP17
Ribosomal RNA-processing protein 17

4

0

High-throughput

0.648

High

703090

MRT4
Ribosome assembly factor MRT4

3

2

Small-scale

0.640

High

715468

RRP1
Ribosomal RNA-processing protein 1

3

5

Small-scale

0.640

High

754891

SSF1
Ribosome biogenesis protein SSF1

3

2

High-throughput

0.640

High

866275

RLP24
Ribosome biogenesis protein RLP24

3

2

Small-scale

0.640

High

866276

BUD20
Bud site selection protein 20

3

0

High-throughput

0.638

High

648411

NSR1
Nuclear localization sequence-binding protein

1

19

High-throughput

0.618

High

866253

SPP1
COMPASS component SPP1

1

3

High-throughput

0.618

High

797379

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

0

Small-scale

0.613

High

534819

RL30
Large ribosomal subunit protein eL30

2

1

High-throughput

0.611

High

535077

RL3
Large ribosomal subunit protein uL3

2

3

High-throughput

0.611

High

667250

RL8B
Large ribosomal subunit protein eL8B

2

5

High-throughput

0.611

High

866263

RRP5
rRNA biogenesis protein RRP5

2

12

High-throughput

0.611

High

357714

RL28
Large ribosomal subunit protein uL15

2

0

High-throughput

0.585

High

405759

RL26A
Large ribosomal subunit protein uL24A

2

3

High-throughput

0.584

High

480244

RS6A
Small ribosomal subunit protein eS6A

2

3

High-throughput

0.584

High

481056

RL23B
Large ribosomal subunit protein uL14B

2

2

Small-scale

0.584

High

481200

RL1A
Large ribosomal subunit protein uL1A

2

6

High-throughput

0.584

High

501237

MAK16
Protein MAK16

2

1

High-throughput

0.584

High

564346

RL8A
Large ribosomal subunit protein eL8A

2

5

Small-scale

0.584

High

594062

MAK11
Protein MAK11

2

20

Small-scale

0.584

High

630883

NLE1
Ribosome assembly protein 4

2

17

Small-scale

0.584

High

634720

KRR1
KRR1 small subunit processome component

2

2

High-throughput

0.584

High

744224

MAK5
ATP-dependent RNA helicase MAK5

2

20

High-throughput

0.584

High

757313

FKBP3
Peptidyl-prolyl cis-trans isomerase

2

5

High-throughput

0.584

High

792535

UTP10
U3 small nucleolar RNA-associated protein 10

2

1

High-throughput

0.584

High

866260

PUF6
Pumilio homology domain family member 6

2

9

Small-scale

0.584

High

866266

FKBP4
FK506-binding protein 4

2

5

High-throughput

0.584

High

866268

DBP9
ATP-dependent RNA helicase DBP9

2

13

High-throughput

0.584

High

866272

NOC4
Nucleolar complex protein 4

2

5

High-throughput

0.584

High

866274

NOC3
Nucleolar complex-associated protein 3

2

3

High-throughput

0.584

High

866282

NIP7
60S ribosome subunit biogenesis protein NIP7

2

1

High-throughput

0.584

High

499026

RL4A
Large ribosomal subunit protein uL4A

2

5

High-throughput

0.571

High

753690

RL14B
Large ribosomal subunit protein eL14B

2

3

High-throughput

0.571

High

732236

RRP14
Ribosomal RNA-processing protein 14

2

0

High-throughput

0.559

High

748676

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

766583

NOP16
Nucleolar protein 16

2

0

High-throughput

0.559

High

859979

CGR1
rRNA-processing protein CGR1

2

0

Small-scale

0.559

High

866271

RRP15
Ribosomal RNA-processing protein 15

2

0

High-throughput

0.559

High

366706

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.541

High

864574

BRE5
UBP3-associated protein BRE5

1

16

High-throughput

0.536

High

866249

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

7

High-throughput

0.536

High

866254

GCN5
Histone acetyltransferase GCN5

1

16

High-throughput

0.536

High

471813

RL27A
Large ribosomal subunit protein eL27A

2

1

High-throughput

0.533

High

478953

RL20B
Large ribosomal subunit protein eL20B

2

1

High-throughput

0.533

High

706418

RS3A1
Small ribosomal subunit protein eS1A

2

1

High-throughput

0.533

High

755848

LSM12
Protein LSM12

1

2

High-throughput

0.515

High

860510

TWF1
Twinfilin-1

1

0

High-throughput

0.513

High

866279

DNLI4
DNA ligase 4

1

0

High-throughput

0.513

High

759420

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

145771

RL36B
Large ribosomal subunit protein eL36B

1

1

High-throughput

0.479

High

404664

RL7A
Large ribosomal subunit protein uL30A

1

5

High-throughput

0.479

High

405245

RL17A
Large ribosomal subunit protein uL22A

1

2

High-throughput

0.479

High

406041

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.479

High

406590

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.479

High

408049

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

426086

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

471427

RL11A
Large ribosomal subunit protein uL5A

1

2

High-throughput

0.479

High

471925

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.479

High

481684

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

481808

RS16B
Small ribosomal subunit protein uS9B

1

5

High-throughput

0.479

High

482766

RL19B
Large ribosomal subunit protein eL19

1

3

High-throughput

0.479

High

482913

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.479

High

492066

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.479

High

544205

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

549459

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.479

High

597875

PWP1
Periodic tryptophan protein 1

1

16

High-throughput

0.479

High

605113

XRN1
5'-3' exoribonuclease 1

1

4

High-throughput

0.479

High

621501

RL24B
Large ribosomal subunit protein eL24B

1

2

High-throughput

0.479

High

632017

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

641029

RL5
Large ribosomal subunit protein uL18

1

4

High-throughput

0.479

High

645255

RL16B
Large ribosomal subunit protein uL13B

1

4

High-throughput

0.479

High

662982

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

663899

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.479

High

688359

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

691405

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

5

High-throughput

0.479

High

698179

AFG2
ATPase family gene 2 protein

1

8

High-throughput

0.479

High

700086

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

2

High-throughput

0.479

High

704395

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

2

High-throughput

0.479

High

707122

DCA13
Protein SOF1

1

12

High-throughput

0.479

High

710911

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

Small-scale

0.479

High

732766

RL14A
Large ribosomal subunit protein eL14A

1

3

High-throughput

0.479

High

733585

RL1D1
Ribosome biogenesis protein UTP30

1

3

High-throughput

0.479

High

752594

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

755249

IPI1
Pre-rRNA-processing protein IPI1

1

1

High-throughput

0.479

High

765649

BEM2
GTPase-activating protein BEM2/IPL2

1

5

High-throughput

0.479

High

766335

SNU13
13 kDa ribonucleoprotein-associated protein

1

5

High-throughput

0.479

High

770430

RL13B
Large ribosomal subunit protein eL13B

1

4

High-throughput

0.479

High

784191

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

810276

RL17B
Large ribosomal subunit protein uL22B

1

2

High-throughput

0.479

High

810895

MTR4
ATP-dependent RNA helicase DOB1

1

17

High-throughput

0.479

High

811333

NOP9
Nucleolar protein 9

1

1

High-throughput

0.479

High

811539

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

3

High-throughput

0.479

High

829656

RL4B
Large ribosomal subunit protein uL4B

1

5

High-throughput

0.479

High

860242

RL26B
Large ribosomal subunit protein uL24B

1

3

High-throughput

0.479

High

866026

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

866245

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

4

High-throughput

0.479

High

866246

RCM1
25S rRNA

1

2

High-throughput

0.479

High

866247

ORC1
Origin recognition complex subunit 1

1

7

High-throughput

0.479

High

866248

ACT
Actin

1

9

High-throughput

0.479

High

866250

RL6A
Large ribosomal subunit protein eL6A

1

3

High-throughput

0.479

High

866251

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.479

High

866258

DHR1
Probable ATP-dependent RNA helicase DHR1

1

5

High-throughput

0.479

High

866259

RRB1
Ribosome assembly protein RRB1

1

8

High-throughput

0.479

High

866261

UTP14
U3 small nucleolar RNA-associated protein 14

1

4

High-throughput

0.479

High

866270

RRP9
Ribosomal RNA-processing protein 9

1

20

High-throughput

0.479

High

866285

FCF2
rRNA-processing protein FCF2

1

1

High-throughput

0.479

High

866287

SSF2
Ribosome biogenesis protein SSF2

1

2

High-throughput

0.479

High

866291

NOP56
Nucleolar protein 56

1

5

High-throughput

0.479

High

866292

NOP58
Nucleolar protein 58

1

5

High-throughput

0.479

High

866293

CMR1
DNA damage-binding protein CMR1

1

11

High-throughput

0.479

High

866295

RL13A
Large ribosomal subunit protein eL13A

1

4

High-throughput

0.479

High

866299

NOP14
Nucleolar complex protein 14

1

1

High-throughput

0.479

High

866289

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

413646

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

446205

MYO1
Myosin-1

1

0

High-throughput

0.458

High

482393

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

645581

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

655877

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.458

High

730055

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

746257

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

754373

RPP1
Ribonuclease P/MRP protein subunit RPP1

1

0

High-throughput

0.458

High

768098

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

774583

BMT5
25S rRNA

1

0

High-throughput

0.458

High

784518

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

810583

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.458

High

824790

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

858812

DXO
Decapping nuclease RAI1

1

0

High-throughput

0.458

High

866244

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

866264

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.458

High

866265

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

866269

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

866280

SGO1
Shugoshin

1

0

High-throughput

0.458

High

866298

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

1

0

High-throughput

0.458

High

866300

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

368294

EF1A
Elongation factor 1-alpha

1

8

High-throughput

0.445

High

424652

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

512284

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

472330

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

472521

RL31B
Large ribosomal subunit protein eL31B

1

3

High-throughput

0.437

High

479154

RL43B
Large ribosomal subunit protein eL43B

1

1

Small-scale

0.437

High

479512

RS24A
Small ribosomal subunit protein eS24A

1

1

High-throughput

0.437

High

480810

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

481966

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.437

High

700556

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

860340

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.437

High

866297

RS28A
Small ribosomal subunit protein eS28A

1

1

High-throughput

0.437

High

762447

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024