Protein: KOG1
Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24) (Regulatory-associated protein of TOR) (Raptor)

Gene: KOG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 236
UniProt ID: P38873

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0001558 - regulation of cell growth
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

752112

KSP1
Serine/threonine-protein kinase KSP1

5

15

Small-scale

0.933

High

715187

TOR1
Serine/threonine-protein kinase TOR1

18

14

Small-scale

0.763

High

548530

GCN2
eIF-2-alpha kinase GCN2

1

4

Small-scale

0.747

High

756556

RAGAB
GTP-binding protein GTR1

7

6

Small-scale

0.740

High

756514

LST8
Target of rapamycin complex subunit LST8

5

18

Small-scale

0.716

High

679963

2AAA
Protein phosphatase PP2A regulatory subunit A

1

8

High-throughput

0.713

High

756596

TCO89
Target of rapamycin complex 1 subunit TCO89

6

0

Small-scale

0.702

High

526234

KIN2
Serine/threonine-protein kinase KIN2

1

9

High-throughput

0.691

High

605735

NPR1
Nitrogen permease reactivator protein

1

10

High-throughput

0.691

High

693708

IME2
Meiosis induction protein kinase IME2/SME1

1

7

High-throughput

0.691

High

730467

NNK1
Nitrogen network kinase 1

1

12

High-throughput

0.691

High

756540

FMP48
Probable serine/threonine-protein kinase FMP48

1

5

High-throughput

0.691

High

756558

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

7

High-throughput

0.691

High

756538

PIB2
Glutamine sensor PIB2

5

0

Small-scale

0.682

High

696499

TOR2
Serine/threonine-protein kinase TOR2

4

14

Small-scale

0.680

High

493939

HSP72
Heat shock protein SSA2

4

16

Small-scale

0.669

High

756543

RAGCD
GTP-binding protein GTR2

3

6

Small-scale

0.664

High

419692

RHO1
GTP-binding protein RHO1

2

16

Small-scale

0.624

High

339623

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.621

High

649889

CDC15
Cell division control protein 15

1

18

High-throughput

0.621

High

743874

AKL1
Serine/threonine-protein kinase AKL1

1

5

High-throughput

0.621

High

756488

KOG1
Target of rapamycin complex 1 subunit KOG1

1

18

High-throughput

0.621

High

756498

KC13
Casein kinase I homolog 3

1

14

High-throughput

0.621

High

755574

UBA4
Adenylyltransferase and sulfurtransferase UBA4

2

1

Small-scale

0.620

High

756521

SCD6
Protein SCD6

2

1

Small-scale

0.619

High

731696

SDS22
Protein phosphatase 1 regulatory subunit SDS22

2

1

Small-scale

0.619

High

756545

DCP2
m7GpppN-mRNA hydrolase

2

0

High-throughput

0.600

High

756572

TAP42
Type 2A phosphatase-associated protein 42

2

0

Small-scale

0.598

High

368047

EF1A
Elongation factor 1-alpha

2

2

Small-scale

0.594

High

477274

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

13

Small-scale

0.594

High

554640

HSP26
Heat shock protein 26

2

3

High-throughput

0.594

High

709295

MKS1
Negative regulator of RAS-cAMP pathway

2

0

Small-scale

0.585

High

448206

F16P
Fructose-1,6-bisphosphatase

2

1

Small-scale

0.584

High

450042

HSP73
Heat shock protein SSA3

2

16

High-throughput

0.584

High

511276

SSB1
Ribosome-associated molecular chaperone SSB1

2

17

High-throughput

0.584

High

540577

CYPH
Peptidyl-prolyl cis-trans isomerase

2

2

High-throughput

0.571

High

756512

SA185
SIT4-associating protein SAP185

2

1

High-throughput

0.560

High

756544

PBP1
PAB1-binding protein 1

2

0

Small-scale

0.559

High

586243

EXO70
Exocyst complex component EXO70

1

2

High-throughput

0.552

High

605027

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.552

High

675734

RENT1
ATP-dependent helicase NAM7

1

1

High-throughput

0.552

High

691796

EI2BB
Translation initiation factor eIF2B subunit beta

1

5

High-throughput

0.552

High

713285

WHI3
Protein WHI3

1

1

High-throughput

0.552

High

756491

DHH1
ATP-dependent RNA helicase DHH1

1

9

High-throughput

0.552

High

756497

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

1

High-throughput

0.552

High

756505

GMT1
GDP-mannose transporter 1

1

1

High-throughput

0.552

High

756547

HCH1
Hsp90 co-chaperone HCH1

1

1

High-throughput

0.552

High

756601

CHS5
Chitin biosynthesis protein CHS5

1

1

High-throughput

0.552

High

589286

FKBP
FK506-binding protein 1

1

4

Small-scale

0.536

High

676042

XPO1
Exportin-1

1

13

High-throughput

0.536

High

756534

SAP4
SIT4-associating protein SAP4

1

1

High-throughput

0.536

High

622018

SSD1
Protein SSD1

1

0

High-throughput

0.529

High

696733

RTG2
Retrograde regulation protein 2

1

0

High-throughput

0.529

High

746923

SLM4
Protein SLM4

1

0

High-throughput

0.529

High

755813

LSM12
Protein LSM12

1

0

High-throughput

0.529

High

756499

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.529

High

756532

PSP2
Protein PSP2

1

0

High-throughput

0.529

High

756533

MUP1
High-affinity methionine permease

1

0

High-throughput

0.529

High

756536

MTHR2
Methylenetetrahydrofolate reductase 2

1

0

High-throughput

0.529

High

756594

AB140
tRNA(Thr)

1

0

High-throughput

0.529

High

756603

NMD4
Nonsense-mediated decay protein 4

1

0

High-throughput

0.529

High

756612

DCP1
mRNA-decapping enzyme subunit 1

1

0

High-throughput

0.529

High

745419

RTG3
Retrograde regulation protein 3

1

0

High-throughput

0.513

High

521190

EI2BD
Translation initiation factor eIF2B subunit delta

1

5

High-throughput

0.504

High

643037

BUB3
Cell cycle arrest protein BUB3

1

16

Small-scale

0.501

High

588069

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.500

High

756526

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.500

High

756609

HSP42
Heat shock protein 42

1

3

High-throughput

0.500

High

756515

MAF1
Repressor of RNA polymerase III transcription MAF1

1

0

Small-scale

0.493

High

145909

YO304
Uncharacterized protein YOR304C-A

1

1

High-throughput

0.481

High

336678

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.481

High

341660

ARGI
Arginase

1

2

High-throughput

0.481

High

373466

PUR1
Amidophosphoribosyltransferase

1

2

High-throughput

0.481

High

409991

NOT3
General negative regulator of transcription subunit 3

1

1

High-throughput

0.481

High

439516

FUMH
Fumarate hydratase, mitochondrial

1

3

High-throughput

0.481

High

488464

YEY2
Uncharacterized protein YER152C

1

1

High-throughput

0.481

High

570691

HXKG
Glucokinase-1

1

1

High-throughput

0.481

High

597129

ACE2
Metallothionein expression activator

1

5

High-throughput

0.481

High

613120

URE2
Transcriptional regulator URE2

1

1

High-throughput

0.481

High

626442

ERG6
Sterol 24-C-methyltransferase ERG6

1

3

High-throughput

0.481

High

699784

KPR1
Ribose-phosphate pyrophosphokinase 1

1

3

High-throughput

0.481

High

680695

HS104
Heat shock protein 104

1

3

High-throughput

0.481

High

686915

PROB
Glutamate 5-kinase

1

2

High-throughput

0.481

High

689721

MDHP
Malate dehydrogenase, peroxisomal

1

4

High-throughput

0.481

High

713170

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

20

Small-scale

0.481

High

743802

ATPG
ATP synthase subunit gamma, mitochondrial

1

2

High-throughput

0.481

High

756494

BDH1
(R,R)-butanediol dehydrogenase

1

2

High-throughput

0.481

High

756495

FLC2
Flavin carrier protein 2

1

1

High-throughput

0.481

High

756502

SERA
D-3-phosphoglycerate dehydrogenase 1

1

7

High-throughput

0.481

High

756504

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

3

High-throughput

0.481

High

756509

SER33
D-3-phosphoglycerate dehydrogenase 2

1

7

High-throughput

0.481

High

756520

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.481

High

756525

BNA3
Probable kynurenine--oxoglutarate transaminase BNA3

1

1

High-throughput

0.481

High

756539

IMO32
Probable alcohol acetyltransferase

1

2

High-throughput

0.481

High

756542

YG3A
Uncharacterized protein YGR130C

1

14

High-throughput

0.481

High

756548

CA120
CCR4-NOT transcriptional complex subunit CAF120

1

1

High-throughput

0.481

High

756549

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.481

High

756554

DAK1
Dihydroxyacetone kinase 1

1

1

High-throughput

0.481

High

756564

RT17
Small ribosomal subunit protein uS17m

1

3

High-throughput

0.481

High

756567

GLRX3
Monothiol glutaredoxin-3

1

14

High-throughput

0.481

High

756574

ADH6
NADP-dependent alcohol dehydrogenase 6

1

2

High-throughput

0.481

High

756577

ERP1
Protein ERP1

1

8

High-throughput

0.481

High

756580

SKG3
Protein SKG3

1

1

High-throughput

0.481

High

756593

MCA1
Metacaspase-1

1

1

High-throughput

0.481

High

756606

KPR5
Ribose-phosphate pyrophosphokinase 5

1

3

High-throughput

0.481

High

376781

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

5

Small-scale

0.479

High

485726

IF4A
ATP-dependent RNA helicase eIF4A

1

8

Small-scale

0.479

High

543709

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

604262

MDHC
Malate dehydrogenase, cytoplasmic

1

4

Small-scale

0.479

High

705161

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.479

High

756503

IMB4
Importin subunit beta-4

1

5

Small-scale

0.479

High

756541

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

Small-scale

0.479

High

756559

NOP3
Serine/arginine

1

8

Small-scale

0.479

High

756590

LAM6
Membrane-anchored lipid-binding protein LAM6

1

2

Small-scale

0.479

High

756598

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

756605

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

Small-scale

0.479

High

756607

IQG1
Ras GTPase-activating-like protein IQG1

1

7

Small-scale

0.479

High

756611

LAS17
Proline-rich protein LAS17

1

5

Small-scale

0.479

High

400157

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.460

High

507798

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase

1

0

High-throughput

0.460

High

587913

PNPP
4-nitrophenylphosphatase

1

0

High-throughput

0.460

High

594129

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

High-throughput

0.460

High

611617

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.460

High

622218

SEC14
SEC14 cytosolic factor

1

0

High-throughput

0.460

High

648316

GYS2
Glycogen [starch] synthase isoform 2

1

0

High-throughput

0.460

High

660222

AROC
Chorismate synthase ARO2

1

0

High-throughput

0.460

High

696718

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.460

High

698369

TMN1
Transmembrane 9 superfamily member 1

1

0

High-throughput

0.460

High

710059

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.460

High

710415

PIN4
RNA-binding protein PIN4

1

0

High-throughput

0.460

High

730751

NDK
Nucleoside diphosphate kinase

1

0

High-throughput

0.460

High

732486

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.460

High

734100

TVP38
Golgi apparatus membrane protein TVP38

1

0

High-throughput

0.460

High

741292

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.460

High

755269

SDO1L
Restriction of telomere capping protein 3

1

0

High-throughput

0.460

High

755605

DNPEP
Aspartyl aminopeptidase 4

1

0

High-throughput

0.460

High

756343

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.460

High

756493

KTD1
Protein-toxin resistance protein KTD1

1

0

High-throughput

0.460

High

756508

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.460

High

756516

EMP47
Protein EMP47

1

0

High-throughput

0.460

High

756517

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.460

High

756524

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.460

High

756528

YJ94
Uncharacterized membrane protein YJR124C

1

0

High-throughput

0.460

High

756531

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.460

High

756537

PNC1
Nicotinamidase

1

0

High-throughput

0.460

High

756546

YN8Z
Uncharacterized vacuolar membrane protein YNR061C

1

0

High-throughput

0.460

High

756550

DUG3
Probable glutamine amidotransferase DUG3

1

0

High-throughput

0.460

High

756555

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.460

High

756557

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.460

High

756565

YD210
Cysteine-rich and transmembrane domain-containing protein YDR210W

1

0

High-throughput

0.460

High

756566

MIX17
Mitochondrial intermembrane space cysteine motif-containing protein MIX17

1

0

High-throughput

0.460

High

756571

ICY1
Interacting with cytoskeleton protein 1

1

0

High-throughput

0.460

High

756573

KAR5
Nuclear fusion protein KAR5

1

0

High-throughput

0.460

High

756576

IVY1
Protein IVY1

1

0

High-throughput

0.460

High

756579

KYNU
Kynureninase

1

0

High-throughput

0.460

High

756581

YPQ2
Vacuolar arginine/histidine antiporter YPQ2

1

0

High-throughput

0.460

High

756585

PUN1
Protein PUN1

1

0

High-throughput

0.460

High

756589

SNA4
Protein SNA4

1

0

High-throughput

0.460

High

756591

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.460

High

756595

TIM18
Mitochondrial import inner membrane translocase subunit TIM18

1

0

High-throughput

0.460

High

756599

VPS68
Vacuolar protein sorting-associated protein 68

1

0

High-throughput

0.460

High

756600

YP162
Vacuolar membrane protein YPL162C

1

0

High-throughput

0.460

High

756602

TMS1
Membrane protein TMS1

1

0

High-throughput

0.460

High

756604

FCY1
Cytosine deaminase

1

0

High-throughput

0.460

High

756608

MAM3
Protein MAM3

1

0

High-throughput

0.460

High

756610

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.460

High

635859

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.458

High

657025

ACEA
Isocitrate lyase

1

0

Small-scale

0.458

High

689751

SFP1
Transcription factor SFP1

1

0

Small-scale

0.458

High

756490

POP2
Poly(A) ribonuclease POP2

1

0

Small-scale

0.458

High

756519

ALK1
Serine/threonine-protein kinase Haspin homolog ALK1

1

0

High-throughput

0.458

High

756569

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

756578

PAL1
Protein PAL1

1

0

High-throughput

0.458

High

756588

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

604406

CLH
Clathrin heavy chain

1

3

High-throughput

0.457

High

756592

RTC1
Restriction of telomere capping protein 1

1

16

High-throughput

0.457

High

366276

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

627614

NAP1
Nucleosome assembly protein

1

2

High-throughput

0.445

High

633216

MAS5
Mitochondrial protein import protein MAS5

1

11

High-throughput

0.445

High

690618

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

4

High-throughput

0.445

High

733246

SET3
SET domain-containing protein 3

1

16

High-throughput

0.445

High

756506

SSB2
Ribosome-associated molecular chaperone SSB2

1

17

High-throughput

0.445

High

756529

IML1
Vacuolar membrane-associated protein IML1

1

5

High-throughput

0.445

High

756535

HOS2
Probable histone deacetylase HOS2

1

15

High-throughput

0.445

High

756551

PFD4
Prefoldin subunit 4

1

4

High-throughput

0.445

High

756552

APJ1
J domain-containing protein APJ1

1

12

High-throughput

0.445

High

756563

HOS3
Histone deacetylase HOS3

1

18

High-throughput

0.445

High

446990

EI2BG
Translation initiation factor eIF2B subunit gamma

1

2

High-throughput

0.439

High

561870

TUP1
General transcriptional corepressor TUP1

1

19

High-throughput

0.439

High

577301

GLN3
Nitrogen regulatory protein GLN3

1

6

High-throughput

0.439

High

690198

CDC3
Cell division control protein 3

1

10

High-throughput

0.439

High

696967

YEF3
Uncharacterized protein YEL043W

1

1

High-throughput

0.439

High

756489

SKN7
Transcription factor SKN7

1

6

High-throughput

0.439

High

756513

MAD1
Spindle assembly checkpoint component MAD1

1

14

High-throughput

0.439

High

756560

MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)]

1

2

High-throughput

0.439

High

756561

CENPP
Inner kinetochore subunit CTF19

1

1

High-throughput

0.439

High

756597

FLC1
Flavin carrier protein 1

1

1

High-throughput

0.439

High

514557

BIK1
Nuclear fusion protein BIK1

1

7

Small-scale

0.437

High

523380

SRS2
ATP-dependent DNA helicase SRS2

1

1

High-throughput

0.437

High

619465

PSA2
Proteasome subunit alpha type-2

1

3

High-throughput

0.437

High

662190

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

687606

DGR2
2-deoxy-glucose resistant protein 2

1

18

High-throughput

0.437

High

756500

BIM1
Protein BIM1

1

5

Small-scale

0.437

High

756510

MPH1
ATP-dependent DNA helicase MPH1

1

9

High-throughput

0.437

High

756553

EF3B
Elongation factor 3B

1

3

Small-scale

0.437

High

745379

SEA4
SEH-associated protein 4

1

0

High-throughput

0.426

High

756492

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

744553

SWD3
COMPASS component SWD3

1

17

High-throughput

0.407

High

755766

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

13

High-throughput

0.407

High

756522

STU2
Protein STU2

1

3

High-throughput

0.407

High

756587

BRE1
E3 ubiquitin-protein ligase BRE1

1

16

High-throughput

0.407

High

756562

LGE1
Transcriptional regulatory protein LGE1

3

0

High-throughput

0.330

High

501288

PCKA
Phosphoenolpyruvate carboxykinase

2

0

Small-scale

0.306

High

693400

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.288

High

688063

VPH2
Vacuolar ATPase assembly integral membrane protein VPH2

1

0

High-throughput

0.279

Low

482644

MTCU2
Copper metallothionein 1-2

1

0

High-throughput

0.251

Low

536688

SNA3
Protein SNA3

1

0

High-throughput

0.251

Low

732282

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.251

Low

756496

HPH2
Protein HPH2

1

0

High-throughput

0.251

Low

756501

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

756507

PEX17
Peroxisomal membrane protein PEX17

1

0

High-throughput

0.251

Low

756518

BLM10
Proteasome activator BLM10

1

0

High-throughput

0.251

Low

756523

STB2
Protein STB2

1

0

High-throughput

0.251

Low

756527

VPS55
Vacuolar protein sorting-associated protein 55

1

0

High-throughput

0.251

Low

756530

ECL1
Extender of the chronological lifespan protein 1

1

0

High-throughput

0.251

Low

756568

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.251

Low

756575

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

756582

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

756583

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.251

Low

756584

YP084
Uncharacterized protein YPR084W

1

0

High-throughput

0.251

Low

756586

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

High-throughput

0.251

Low

756613

ISN1
IMP-specific 5'-nucleotidase 1

1

0

High-throughput

0.251

Low

756511

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

756570

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

689877

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024