Protein: SP105
Spindle pole body component SPC105 (105 kDa spindle pole component protein)

Gene: SP105, SPC105
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: P53148

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005739 - mitochondrion
GO:0005816 - spindle pole body
GO:0007094 - mitotic spindle assembly checkpoint signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

775788

DSN1
Kinetochore-associated protein DSN1

19

0

Small-scale

0.730

High

859671

KRE28
Spindle pole body component KRE28

6

0

Small-scale

0.704

High

763943

MTW1
Kinetochore-associated protein MTW1

3

1

Small-scale

0.681

High

859672

SPC24
Kinetochore protein SPC24

5

0

Small-scale

0.676

High

859667

MPS1
Serine/threonine-protein kinase MPS1

4

0

Small-scale

0.667

High

708030

NUF2
Kinetochore protein NUF2

3

1

Small-scale

0.658

High

798054

CENPT
Inner kinetochore subunit CNN1

3

0

Small-scale

0.639

High

774059

NDC80
Kinetochore protein NDC80

2

1

Small-scale

0.635

High

766807

SPC25
Kinetochore protein SPC25

3

0

Small-scale

0.633

High

859663

SP105
Spindle pole body component SPC105

1

0

High-throughput

0.631

High

812415

NNF1
Kinetochore-associated protein NNF1

3

0

High-throughput

0.627

High

748291

CENPU
Inner kinetochore subunit AME1

3

0

Small-scale

0.614

High

859684

NSL1
Kinetochore-associated protein NSL1

2

0

Small-scale

0.598

High

859683

SLK19
Kinetochore protein SLK19

2

0

High-throughput

0.576

High

731335

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.493

High

734072

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.493

High

859674

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.493

High

521147

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.460

High

797080

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.460

High

811182

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.460

High

859668

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.460

High

859686

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.460

High

643045

BUB3
Cell cycle arrest protein BUB3

1

0

Small-scale

0.458

High

716100

CENPC
Inner kinetochore subunit MIF2

1

0

Small-scale

0.458

High

746174

STU1
Protein STU1

1

0

Small-scale

0.458

High

778464

MAD1
Spindle assembly checkpoint component MAD1

1

0

Small-scale

0.458

High

783850

BUB1
Checkpoint serine/threonine-protein kinase BUB1

1

0

Small-scale

0.458

High

859665

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

859669

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

859678

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.458

High

859682

SGO1
Shugoshin

1

0

High-throughput

0.458

High

859685

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

756267

KEL1
Kelch repeat-containing protein 1

1

1

High-throughput

0.439

High

837237

KEL2
Kelch repeat-containing protein 2

1

1

High-throughput

0.439

High

539576

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.438

High

859680

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

Small-scale

0.437

High

859687

CENPI
Inner kinetochore subunit CTF3

1

0

High-throughput

0.426

High

512080

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

695145

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.407

High

731127

LHS1
Heat shock protein 70 homolog LHS1

1

1

High-throughput

0.407

High

768989

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

759243

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.269

Low

491898

HSP71
Heat shock protein SSA1

1

0

Small-scale

0.261

Low

145915

YO304
Uncharacterized protein YOR304C-A

1

0

High-throughput

0.251

Low

410015

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.251

Low

599921

RE107
Recombination protein 107

1

0

High-throughput

0.251

Low

605671

KIN3
Serine/threonine-protein kinase KIN3

1

0

High-throughput

0.251

Low

623491

KPC1
Protein kinase C-like 1

1

0

High-throughput

0.251

Low

688656

MCM10
Minichromosome maintenance protein 10

1

0

High-throughput

0.251

Low

710793

CASP
Protein CASP

1

0

High-throughput

0.251

Low

713194

SCD5
Protein SCD5

1

0

High-throughput

0.251

Low

728118

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

728427

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

733083

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.251

Low

734312

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.251

Low

746754

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

756655

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.251

Low

764864

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.251

Low

766496

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.251

Low

767527

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

784627

BNI1
Protein BNI1

1

0

High-throughput

0.251

Low

785594

REF2
RNA end formation protein 2

1

0

High-throughput

0.251

Low

859209

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.251

Low

859664

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.251

Low

859666

IPI3
Pre-rRNA-processing protein IPI3

1

0

High-throughput

0.251

Low

859670

SNX41
Sorting nexin-41

1

0

High-throughput

0.251

Low

859673

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

859675

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.251

Low

859676

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.251

Low

859677

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

859681

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.251

Low

859688

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

662831

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

689271

SP110
Spindle pole body component 110

1

0

Small-scale

0.232

Low

859679

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024