Protein: SHAN2
SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1)

Gene: SHAN2, SHANK2
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q9UPX8

Gene Ontology (top 5):
GO:0001750 - photoreceptor outer segment
GO:0001917 - photoreceptor inner segment
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007416 - synapse assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1049744

ARHG7
Rho guanine nucleotide exchange factor 7

2

20

Small-scale

0.815

High

1353980

NLK
Serine/threonine-protein kinase NLK

2

13

High-throughput

0.811

High

145956

DLGP1
Disks large-associated protein 1

2

20

Small-scale

0.800

High

1357784

BAIP2
BAR/IMD domain-containing adapter protein 2

2

20

High-throughput

0.783

High

942399

DLG4
Disks large homolog 4

2

17

Small-scale

0.754

High

581080

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

5

High-throughput

0.747

High

1052351

SRC8
Src substrate cortactin

1

20

Small-scale

0.713

High

1219688

RHG12
Rho GTPase-activating protein 12

2

13

High-throughput

0.700

High

682072

AKT1
RAC-alpha serine/threonine-protein kinase

1

12

Small-scale

0.647

High

1355560

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

10

Small-scale

0.647

High

327248

DLGP3
Disks large-associated protein 3

1

20

Small-scale

0.621

High

1349917

DLGP2
Disks large-associated protein 2

1

20

Small-scale

0.621

High

1357785

DLGP4
Disks large-associated protein 4

1

20

Small-scale

0.621

High

339143

EGFR
Epidermal growth factor receptor

1

12

High-throughput

0.618

High

434312

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

15

Small-scale

0.618

High

523212

SRC
Proto-oncogene tyrosine-protein kinase Src

1

12

High-throughput

0.618

High

557831

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

655508

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

12

High-throughput

0.618

High

802780

CRK
Adapter molecule crk

1

18

High-throughput

0.618

High

924955

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

1031725

GRB10
Growth factor receptor-bound protein 10

1

18

Small-scale

0.618

High

994123

PP2BA
Protein phosphatase 3 catalytic subunit alpha

2

8

High-throughput

0.606

High

1205741

HOME1
Homer protein homolog 1

2

20

High-throughput

0.606

High

840865

DYN2
Dynamin-2

1

8

Small-scale

0.573

High

370725

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1316822

ACE2
Angiotensin-converting enzyme 2

1

3

Small-scale

0.527

High

163478

XPO1
Exportin-1

1

12

High-throughput

0.479

High

522276

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

928527

DYL1
Dynein light chain 1, cytoplasmic

1

4

Small-scale

0.479

High

995937

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

3

Small-scale

0.479

High

1291334

DYL2
Dynein light chain 2, cytoplasmic

1

4

Small-scale

0.479

High

1357786

MYO5A
Unconventional myosin-Va

1

7

Small-scale

0.479

High

181483

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

348254

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.445

High

1269944

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

1327720

SHRPN
Sharpin

1

4

Small-scale

0.408

High

1297930

RIPR3
RIPOR family member 3

2

0

High-throughput

0.316

High


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Last updated: 15 Jul 2024