Protein: PPOX
Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4)

Gene: PPOX
Organism: Homo sapiens
Interactions: 72
UniProt ID: P50336

Gene Ontology (top 5):
GO:0004729 - oxygen-dependent protoporphyrinogen oxidase activity
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0006779 - porphyrin-containing compound biosynthetic process
GO:0006782 - protoporphyrinogen IX biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

258682

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

1

High-throughput

0.628

High

838571

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.541

High

838582

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.536

High

838583

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.536

High

838590

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.536

High

226876

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.533

High

203892

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

815351

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

838569

TAZ
Tafazzin

1

0

High-throughput

0.513

High

838581

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

838593

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.513

High

838601

RT02
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.513

High

838560

HAP1
Huntingtin-associated protein 1

1

1

High-throughput

0.494

High

171959

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

838559

CRBA4
Beta-crystallin A4

1

1

High-throughput

0.489

High

838566

KLRD1
Natural killer cells antigen CD94

1

1

High-throughput

0.489

High

838580

TRI43
Tripartite motif-containing protein 43

1

5

High-throughput

0.489

High

838587

LDH6B
L-lactate dehydrogenase A-like 6B

1

1

High-throughput

0.489

High

838591

ANTR1
Anthrax toxin receptor 1

1

1

High-throughput

0.489

High

838594

NPS3A
Protein NipSnap homolog 3A

1

1

High-throughput

0.489

High

258417

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

311219

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

2

High-throughput

0.479

High

308512

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.437

High

823705

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.437

High

832830

TSP3
Thrombospondin-3

1

2

High-throughput

0.437

High

838562

PO5F1
POU domain, class 5, transcription factor 1

1

4

High-throughput

0.437

High

838573

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

838575

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

838592

NANOG
Homeobox protein NANOG

1

1

High-throughput

0.437

High

838599

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.407

High

326305

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

2

0

High-throughput

0.328

High

838574

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

2

0

High-throughput

0.328

High

592160

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.298

High

245219

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

252742

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

0

High-throughput

0.279

Low

263910

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

272341

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

486999

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.279

Low

571101

EGLN
Endoglin

1

0

High-throughput

0.279

Low

614192

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.279

Low

646380

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.279

Low

789612

I12R1
Interleukin-12 receptor subunit beta-1

1

0

High-throughput

0.279

Low

790240

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.279

Low

792749

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.279

Low

824905

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.279

Low

838558

LIMK2
LIM domain kinase 2

1

0

High-throughput

0.279

Low

838561

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.279

Low

838563

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

838565

FMOD
Fibromodulin

1

0

High-throughput

0.279

Low

838567

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

838570

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.279

Low

838572

TECT1
Tectonic-1

1

0

High-throughput

0.279

Low

838576

ETKMT
Electron transfer flavoprotein beta subunit lysine methyltransferase

1

0

High-throughput

0.279

Low

838577

FA83F
Protein FAM83F

1

0

High-throughput

0.279

Low

838579

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

838584

LSMD1
N-alpha-acetyltransferase 38, NatC auxiliary subunit

1

0

High-throughput

0.279

Low

838588

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.279

Low

838589

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.279

Low

838595

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.279

Low

838596

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.279

Low

838597

PCDAC
Protocadherin alpha-12

1

0

High-throughput

0.279

Low

838598

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.279

Low

838600

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

838602

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

838578

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.265

Low

838568

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.251

Low

146325

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.249

Low

546597

ARSA
Arylsulfatase A

1

0

High-throughput

0.249

Low

779029

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

838564

UPAR
Urokinase plasminogen activator surface receptor

1

0

High-throughput

0.249

Low

838585

CAB45
45 kDa calcium-binding protein

1

0

High-throughput

0.249

Low

838586

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024