Protein: TP4A1
Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)

Gene: TP4A1, PTP4A1
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q93096

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005769 - early endosome
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1274604

CNNM1
Metal transporter CNNM1

5

10

High-throughput

0.933

High

1159772

CNNM4
Metal transporter CNNM4

5

10

High-throughput

0.930

High

1242821

CNNM3
Metal transporter CNNM3

5

10

Small-scale

0.930

High

1274603

CNNM2
Metal transporter CNNM2

2

10

High-throughput

0.820

High

1021815

TP4A2
Protein tyrosine phosphatase type IVA 2

7

15

Small-scale

0.748

High

1130411

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

8

High-throughput

0.737

High

1274597

NUD12
NAD-capped RNA hydrolase NUDT12

1

12

High-throughput

0.691

High

850137

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

2

8

High-throughput

0.621

High

659023

MK01
Mitogen-activated protein kinase 1

1

20

High-throughput

0.618

High

1025189

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

5

High-throughput

0.618

High

1082607

MK14
Mitogen-activated protein kinase 14

1

20

High-throughput

0.618

High

1274588

TP4A1
Protein tyrosine phosphatase type IVA 1

1

15

High-throughput

0.618

High

1274617

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

1

High-throughput

0.618

High

1274619

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

2

1

High-throughput

0.611

High

826478

FNTB
Protein farnesyltransferase subunit beta

3

4

High-throughput

0.609

High

863115

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

4

High-throughput

0.609

High

1274590

LRC39
Leucine-rich repeat-containing protein 39

2

1

High-throughput

0.558

High

198685

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

2

High-throughput

0.554

High

907117

PRS8
26S proteasome regulatory subunit 8

1

4

High-throughput

0.554

High

1027745

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

4

High-throughput

0.554

High

1274593

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

4

High-throughput

0.554

High

497402

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.536

High

740950

FDFT
Squalene synthase

1

1

High-throughput

0.536

High

801288

KI67
Proliferation marker protein Ki-67

1

6

High-throughput

0.536

High

826426

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

2

High-throughput

0.536

High

863983

CLH2
Clathrin heavy chain 2

1

6

High-throughput

0.536

High

1058089

PSF1
DNA replication complex GINS protein PSF1

1

1

High-throughput

0.536

High

1274598

SLD5
DNA replication complex GINS protein SLD5

1

1

High-throughput

0.536

High

1274599

PSF3
DNA replication complex GINS protein PSF3

1

1

High-throughput

0.536

High

1274610

PSF2
DNA replication complex GINS protein PSF2

1

1

High-throughput

0.536

High

1274614

TMED5
Transmembrane emp24 domain-containing protein 5

1

3

High-throughput

0.536

High

841475

BPL1
Biotin--protein ligase

1

0

High-throughput

0.530

High

568274

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

2

Small-scale

0.527

High

312763

TFIP8
Tumor necrosis factor alpha-induced protein 8

1

1

High-throughput

0.515

High

309982

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.513

High

1046242

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.513

High

738623

GNL1
Guanine nucleotide-binding protein-like 1

1

4

Small-scale

0.508

High

1174371

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

Small-scale

0.508

High

395394

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

626792

PTAFR
Platelet-activating factor receptor

1

2

High-throughput

0.489

High

1147927

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

3

High-throughput

0.489

High

1274605

ARL15
ADP-ribosylation factor-like protein 15

1

6

High-throughput

0.489

High

1274616

BOLA1
BolA-like protein 1

1

1

High-throughput

0.489

High

254926

CPNE3
Copine-3

1

1

High-throughput

0.479

High

403305

LA
Lupus La protein

1

3

High-throughput

0.479

High

505866

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.479

High

553362

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

575525

EGR1
Early growth response protein 1

1

2

High-throughput

0.479

High

581038

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

2

High-throughput

0.479

High

606464

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

High-throughput

0.479

High

617060

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

4

High-throughput

0.479

High

631210

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

673423

MPIP1
M-phase inducer phosphatase 1

1

3

High-throughput

0.479

High

843827

FXR1
RNA-binding protein FXR1

1

5

High-throughput

0.479

High

878551

PSA
Puromycin-sensitive aminopeptidase

1

1

High-throughput

0.479

High

1017980

GRSF1
G-rich sequence factor 1

1

3

High-throughput

0.479

High

1056384

PLSI
Plastin-1

1

3

High-throughput

0.479

High

1082314

DDB1
DNA damage-binding protein 1

1

6

High-throughput

0.479

High

1240401

TXND5
Thioredoxin domain-containing protein 5

1

9

High-throughput

0.479

High

1240707

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

1243879

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1251115

G45IP
Large ribosomal subunit protein mL64

1

3

High-throughput

0.479

High

1274589

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.479

High

1274591

NUD16
U8 snoRNA-decapping enzyme

1

1

High-throughput

0.479

High

1274594

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

1274600

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

2

High-throughput

0.479

High

1274602

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

1274607

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1274608

MRT4
mRNA turnover protein 4 homolog

1

2

High-throughput

0.479

High

1274613

PDIP2
Polymerase delta-interacting protein 2

1

5

High-throughput

0.479

High

1274615

RNF11
RING finger protein 11

1

3

Small-scale

0.479

High

1274618

COPG1
Coatomer subunit gamma-1

1

8

High-throughput

0.479

High

1274606

ZN212
Zinc finger protein 212

1

3

Small-scale

0.464

High

509264

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.458

High

816367

PPCE
Prolyl endopeptidase

1

0

High-throughput

0.458

High

1183003

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.458

High

1274595

MACD1
ADP-ribose glycohydrolase MACROD1

1

0

High-throughput

0.458

High

1274596

CMS1
Protein CMSS1

1

0

High-throughput

0.458

High

1274609

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.458

High

146378

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

4

High-throughput

0.437

High

153237

ACOT8
Acyl-coenzyme A thioesterase 8

1

1

High-throughput

0.437

High

674963

PUR8
Adenylosuccinate lyase

1

2

High-throughput

0.437

High

721090

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

836661

GUAA
GMP synthase [glutamine-hydrolyzing]

1

1

High-throughput

0.437

High

1184135

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.437

High

1203664

AROS
Active regulator of SIRT1

1

2

High-throughput

0.437

High

1244325

FAD1
FAD synthase

1

3

High-throughput

0.437

High

1274612

RT28
Small ribosomal subunit protein bS1m

1

2

High-throughput

0.437

High

1274601

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.407

High

534208

CD59
CD59 glycoprotein

1

0

High-throughput

0.279

Low

1121584

UNC50
Protein unc-50 homolog

1

0

High-throughput

0.279

Low

1168186

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

1192959

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.279

Low

1250945

OCC1
Overexpressed in colon carcinoma 1 protein

1

0

High-throughput

0.279

Low

1274592

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

0

High-throughput

0.279

Low

857007

THOP1
Thimet oligopeptidase

1

0

High-throughput

0.249

Low

1256526

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.249

Low

1272424

RL3L
Ribosomal protein uL3-like

1

0

High-throughput

0.249

Low

1274611

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024