Protein: ARHGG
Rho guanine nucleotide exchange factor 16 (Ephexin-4)

Gene: ARHGG, ARHGEF16
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q5VV41

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0030165 - PDZ domain binding
GO:0030971 - receptor tyrosine kinase binding
GO:0031267 - small GTPase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021513

DLG1
Disks large homolog 1

3

17

High-throughput

0.827

High

1059990

LASP1
LIM and SH3 domain protein 1

2

9

High-throughput

0.783

High

1138658

TFG
Protein TFG

1

8

High-throughput

0.740

High

924030

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

7

High-throughput

0.737

High

1138649

FGD6
FYVE, RhoGEF and PH domain-containing protein 6

2

14

High-throughput

0.737

High

1138668

ANFY1
Rabankyrin-5

2

10

High-throughput

0.737

High

1138662

IF122
Intraflagellar transport protein 122 homolog

2

5

High-throughput

0.726

High

646986

1433T
14-3-3 protein theta

4

20

High-throughput

0.697

High

904694

1433G
14-3-3 protein gamma

4

20

High-throughput

0.694

High

784026

KPCI
Protein kinase C iota type

1

13

High-throughput

0.691

High

927148

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.683

High

982120

1433F
14-3-3 protein eta

3

20

High-throughput

0.667

High

1033880

SNTB2
Beta-2-syntrophin

2

16

High-throughput

0.659

High

1074138

SF3A1
Splicing factor 3A subunit 1

2

8

High-throughput

0.659

High

683428

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.650

High

681894

AKT1
RAC-alpha serine/threonine-protein kinase

1

12

Small-scale

0.647

High

1049974

SCRIB
Protein scribble homolog

3

15

High-throughput

0.641

High

668749

PML
Protein PML

2

4

High-throughput

0.628

High

349391

RASH
GTPase HRas

1

13

High-throughput

0.618

High

665261

EPHA2
Ephrin type-A receptor 2

1

20

Small-scale

0.618

High

894120

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

915744

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

1138646

A16L1
Autophagy-related protein 16-1

1

16

High-throughput

0.618

High

1138656

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

6

High-throughput

0.618

High

684104

1433S
14-3-3 protein sigma

2

20

High-throughput

0.612

High

682843

HNRH1
Heterogeneous nuclear ribonucleoprotein H

2

4

High-throughput

0.606

High

1138648

DPP8
Dipeptidyl peptidase 8

2

0

High-throughput

0.602

High

1138661

UBAC1
Ubiquitin-associated domain-containing protein 1

2

0

High-throughput

0.602

High

985535

Q05BK6
TFG protein

1

2

High-throughput

0.594

High

1138671

MAGD1
Melanoma-associated antigen D1

2

0

High-throughput

0.580

High

1077886

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

2

3

High-throughput

0.571

High

1138670

E41L3
Band 4.1-like protein 3

2

7

High-throughput

0.571

High

1047745

CKAP5
Cytoskeleton-associated protein 5

1

3

Small-scale

0.561

High

504226

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.536

High

1138652

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

4

High-throughput

0.523

High

489760

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

2

1

High-throughput

0.521

High

713533

GLYM
Serine hydroxymethyltransferase, mitochondrial

2

2

High-throughput

0.521

High

816015

ATPO
ATP synthase subunit O, mitochondrial

2

1

High-throughput

0.521

High

1126201

RABL3
Rab-like protein 3

2

20

High-throughput

0.521

High

1138650

MGAP
MAX gene-associated protein

2

1

High-throughput

0.521

High

909662

1433E
14-3-3 protein epsilon

1

12

High-throughput

0.515

High

147750

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.513

High

271483

LYPA1
Acyl-protein thioesterase 1

1

0

High-throughput

0.513

High

360027

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

10

High-throughput

0.481

High

1138654

LNX1
E3 ubiquitin-protein ligase LNX

1

20

Small-scale

0.481

High

162850

XPO1
Exportin-1

1

1

High-throughput

0.479

High

521993

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

614350

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

5

High-throughput

0.479

High

657367

ABCD3
ATP-binding cassette sub-family D member 3

1

2

High-throughput

0.479

High

684806

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

848052

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.479

High

853320

IMA1
Importin subunit alpha-1

1

3

High-throughput

0.479

High

1076320

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

1

High-throughput

0.479

High

1076977

MARE1
Microtubule-associated protein RP/EB family member 1

1

6

High-throughput

0.479

High

1138655

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

7

High-throughput

0.479

High

1138669

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1138651

BOLL
Protein boule-like

1

2

High-throughput

0.470

High

1138657

ELMO1
Engulfment and cell motility protein 1

1

0

Small-scale

0.458

High

152299

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

8

Small-scale

0.457

High

198908

RFOX2
RNA binding protein fox-1 homolog 2

1

4

High-throughput

0.437

High

214955

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

2

High-throughput

0.437

High

396946

HMGN1
Non-histone chromosomal protein HMG-14

1

4

High-throughput

0.437

High

440567

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.437

High

442230

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

6

High-throughput

0.437

High

552926

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

623942

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

1

High-throughput

0.437

High

809126

UTRN
Utrophin

1

9

High-throughput

0.437

High

1058735

LBR
Delta(14)-sterol reductase LBR

1

2

High-throughput

0.437

High

1137512

RIF1
Telomere-associated protein RIF1

1

7

High-throughput

0.437

High

1138647

RL22L
Ribosomal protein eL22-like

1

1

High-throughput

0.437

High

1138659

HDAC2
Histone deacetylase 2

1

8

High-throughput

0.437

High

1138663

LIN7C
Protein lin-7 homolog C

1

20

High-throughput

0.437

High

1138665

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

1

High-throughput

0.437

High

1138666

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

3

High-throughput

0.437

High

1138667

HACD3
Very-long-chain

1

1

High-throughput

0.437

High

1120228

CEP55
Centrosomal protein of 55 kDa

1

1

High-throughput

0.417

High

843460

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

2

0

High-throughput

0.328

High

1138653

COQ8A
Atypical kinase COQ8A, mitochondrial

2

0

High-throughput

0.298

High

1138660

RM53
Large ribosomal subunit protein mL53

2

0

High-throughput

0.298

High

1138664

TM160
Transmembrane protein 160

1

0

High-throughput

0.279

Low

1138672

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.249

Low

1133060

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024