Protein: SFRP4
Secreted frizzled-related protein 4 (sFRP-4) (Frizzled protein, human endometrium) (FrpHE)

Gene: SFRP4
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q6FHJ7

Gene Ontology (top 5):
GO:0002092 - positive regulation of receptor internalization
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008285 - negative regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257627

ANR17
Ankyrin repeat domain-containing protein 17

3

1

High-throughput

0.861

High

1151030

ANKH1
Ankyrin repeat and KH domain-containing protein 1

3

1

High-throughput

0.861

High

986430

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

3

0

High-throughput

0.638

High

1151038

SIR1
NAD-dependent protein deacetylase sirtuin-1

3

0

High-throughput

0.638

High

1151043

TBB1
Tubulin beta-1 chain

3

0

High-throughput

0.638

High

653626

CALR
Calreticulin

2

2

High-throughput

0.628

High

639763

IKBA
NF-kappa-B inhibitor alpha

1

2

Small-scale

0.618

High

1151041

PASK
PAS domain-containing serine/threonine-protein kinase

2

0

High-throughput

0.585

High

1151047

AKA11
A-kinase anchor protein 11

2

0

High-throughput

0.585

High

1151032

DHB11
Estradiol 17-beta-dehydrogenase 11

2

0

High-throughput

0.580

High

1037598

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

211027

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

3

High-throughput

0.541

High

383854

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.541

High

437763

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

1

High-throughput

0.541

High

738358

BMR1A
Bone morphogenetic protein receptor type-1A

1

2

High-throughput

0.541

High

869874

PMS2
Mismatch repair endonuclease PMS2

1

1

High-throughput

0.541

High

983493

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

2

High-throughput

0.541

High

1020098

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

1

High-throughput

0.541

High

1035472

SMAD4
Mothers against decapentaplegic homolog 4

1

2

High-throughput

0.541

High

1135803

DCAF8
DDB1- and CUL4-associated factor 8

1

1

High-throughput

0.536

High

160625

AURKA
Aurora kinase A

1

0

High-throughput

0.518

High

617583

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.518

High

787256

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.518

High

1151037

AP2M1
AP-2 complex subunit mu

1

0

High-throughput

0.518

High

1151040

RHG07
Rho GTPase-activating protein 7

1

0

High-throughput

0.518

High

1087193

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.515

High

147751

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.513

High

348728

RASN
GTPase NRas

1

2

High-throughput

0.494

High

716716

CTNA1
Catenin alpha-1

1

1

High-throughput

0.494

High

1069589

PGFRL
Platelet-derived growth factor receptor-like protein

1

3

High-throughput

0.494

High

790807

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

2

High-throughput

0.481

High

612866

FBLN1
Fibulin-1

1

3

High-throughput

0.479

High

1150509

H2B2C
Putative histone H2B type 2-C

1

1

High-throughput

0.479

High

1151039

DCAF5
DDB1- and CUL4-associated factor 5

1

1

High-throughput

0.479

High

1151036

JPH3
Junctophilin-3

1

1

High-throughput

0.470

High

1151035

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.458

High

1151042

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1151048

DICER
Endoribonuclease Dicer

1

0

High-throughput

0.458

High

1151049

FBW1A
F-box/WD repeat-containing protein 1A

1

0

Small-scale

0.458

High

1151031

ARF
Tumor suppressor ARF

1

0

High-throughput

0.438

High

724375

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

2

High-throughput

0.437

High

1151045

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

4

High-throughput

0.437

High

679253

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

3

0

High-throughput

0.347

High

1151044

DCA16
DDB1- and CUL4-associated factor 16

3

0

High-throughput

0.347

High

1151033

B3GL2
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.318

High

519794

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.282

High

1151046

NARF
Nuclear prelamin A recognition factor

1

0

High-throughput

0.282

High

1151034

RASF8
Ras association domain-containing protein 8

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024