Protein: BBC3B
Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis)

Gene: BBC3B, BBC3
Organism: Homo sapiens
Interactions: 25
UniProt ID: Q96PG8

Gene Ontology (top 5):
GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
GO:0006915 - apoptotic process
GO:0051117 - ATPase binding
GO:0070059 - intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992191

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

10

5

Small-scale

0.752

High

992116

B2CL1
Bcl-2-like protein 1

7

5

Small-scale

0.736

High

489449

BCL2
Apoptosis regulator Bcl-2

4

5

Small-scale

0.683

High

147940

ACPM
Acyl carrier protein, mitochondrial

2

0

High-throughput

0.580

High

387329

P53
Cellular tumor antigen p53

2

0

Small-scale

0.559

High

1271717

B2CL2
Bcl-2-like protein 2

2

5

High-throughput

0.558

High

1299307

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.513

High

992035

BAX
Apoptosis regulator BAX

1

5

Small-scale

0.479

High

246307

NOL3
Nucleolar protein 3

1

0

Small-scale

0.458

High

338860

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.458

High

1036824

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

1083080

B2LA1
Bcl-2-related protein A1

1

5

Small-scale

0.408

High

160159

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.316

High

903447

WDR5
WD repeat-containing protein 5

2

0

High-throughput

0.316

High

1136602

FHL5
Four and a half LIM domains protein 5

2

0

High-throughput

0.316

High

1190651

ZN438
Zinc finger protein 438

2

0

High-throughput

0.316

High

1191191

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

0

High-throughput

0.316

High

1201332

MYPOP
Myb-related transcription factor, partner of profilin

2

0

High-throughput

0.316

High

1257128

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

2

0

High-throughput

0.316

High

1294464

FXL20
F-box/LRR-repeat protein 20

1

0

Small-scale

0.301

High

167599

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

0

Small-scale

0.292

High

363880

ALBU
Albumin

1

0

High-throughput

0.249

Low

575542

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

961420

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

0

Small-scale

0.249

Low

1299306

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024