Protein: H3C
Histone H3.3C (Histone H3.5)

Gene: H3C, H3-5
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q6NXT2

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0000791 - euchromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030307 - positive regulation of cell growth

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

825838

NASP
Nuclear autoantigenic sperm protein

4

16

High-throughput

0.698

High

803587

BAG6
Large proline-rich protein BAG6

1

17

High-throughput

0.665

High

966156

NC2B
Protein Dr1

1

2

High-throughput

0.665

High

203711

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

20

High-throughput

0.656

High

232248

KDM1A
Lysine-specific histone demethylase 1A

1

13

High-throughput

0.656

High

1121356

SETMR
Histone-lysine N-methyltransferase SETMAR

1

20

High-throughput

0.656

High

1157210

SMYD1
Histone-lysine N-methyltransferase SMYD1

1

7

High-throughput

0.656

High

1157224

NSD3
Histone-lysine N-methyltransferase NSD3

1

20

High-throughput

0.656

High

1157230

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

7

High-throughput

0.656

High

917448

H4
Histone H4

1

17

High-throughput

0.618

High

1059677

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.618

High

1080038

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.618

High

1157204

H2AV
Histone H2A.V

1

20

High-throughput

0.618

High

1157215

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.618

High

1157222

H2A1J
Histone H2A type 1-J

1

20

High-throughput

0.618

High

1157235

H2AW
Core histone macro-H2A.2

1

20

High-throughput

0.618

High

1157245

SP16H
FACT complex subunit SPT16

1

9

High-throughput

0.618

High

1157212

DNJC9
DnaJ homolog subfamily C member 9

2

14

High-throughput

0.606

High

1157236

DAXX
Death domain-associated protein 6

2

5

High-throughput

0.606

High

657840

ELK4
ETS domain-containing protein Elk-4

2

12

High-throughput

0.571

High

850669

KS6A3
Ribosomal protein S6 kinase alpha-3

2

13

High-throughput

0.571

High

1071108

RBP1
RalA-binding protein 1

2

8

High-throughput

0.571

High

1157228

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

14

High-throughput

0.571

High

1157240

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

6

High-throughput

0.571

High

1157211

FBLI1
Filamin-binding LIM protein 1

2

3

High-throughput

0.553

High

1062748

FL2D
Pre-mRNA-splicing regulator WTAP

1

1

High-throughput

0.536

High

1157205

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

2

High-throughput

0.536

High

157926

KLF11
Krueppel-like factor 11

1

11

High-throughput

0.515

High

791666

HD
Huntingtin

1

2

High-throughput

0.515

High

919127

RAN
GTP-binding nuclear protein Ran

1

6

High-throughput

0.515

High

1157243

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

1157246

TF3C3
General transcription factor 3C polypeptide 3

1

11

High-throughput

0.515

High

153706

ANM5
Protein arginine N-methyltransferase 5

1

12

High-throughput

0.508

High

301146

KDM4B
Lysine-specific demethylase 4B

1

20

High-throughput

0.508

High

1157220

ANM6
Protein arginine N-methyltransferase 6

1

14

High-throughput

0.508

High

1157234

ANM7
Protein arginine N-methyltransferase 7

1

14

High-throughput

0.508

High

1157214

KAT6A
Histone acetyltransferase KAT6A

1

20

Small-scale

0.501

High

258072

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.493

High

877070

CASP6
Caspase-6

1

0

High-throughput

0.493

High

210078

PRC1
Protein regulator of cytokinesis 1

1

4

High-throughput

0.479

High

308797

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

319881

HERC2
E3 ubiquitin-protein ligase HERC2

1

7

High-throughput

0.479

High

326685

SNAI1
Zinc finger protein SNAI1

1

10

High-throughput

0.479

High

418366

NPM
Nucleophosmin

1

4

High-throughput

0.479

High

455562

PARP1
Poly [ADP-ribose] polymerase 1

1

16

High-throughput

0.479

High

489100

H14
Histone H1.4

1

20

High-throughput

0.479

High

559429

H13
Histone H1.3

1

20

High-throughput

0.479

High

582340

NUCL
Nucleolin

1

6

High-throughput

0.479

High

643358

HMGB2
High mobility group protein B2

1

20

High-throughput

0.479

High

649560

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

708683

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.479

High

826296

CDK8
Cyclin-dependent kinase 8

1

7

High-throughput

0.479

High

855669

KIF11
Kinesin-like protein KIF11

1

14

High-throughput

0.479

High

969779

KIF23
Kinesin-like protein KIF23

1

19

High-throughput

0.479

High

971220

H11
Histone H1.1

1

20

High-throughput

0.479

High

973351

TOP2B
DNA topoisomerase 2-beta

1

12

High-throughput

0.479

High

1063868

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.479

High

1066267

KIF14
Kinesin-like protein KIF14

1

12

High-throughput

0.479

High

1131336

HP1B3
Heterochromatin protein 1-binding protein 3

1

4

High-throughput

0.479

High

1157207

SMC5
Structural maintenance of chromosomes protein 5

1

15

High-throughput

0.479

High

1157218

SPDLY
Protein Spindly

1

11

High-throughput

0.479

High

1157219

AURKB
Aurora kinase B

1

20

High-throughput

0.479

High

1157221

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1157223

OVOL2
Transcription factor Ovo-like 2

1

10

Small-scale

0.479

High

1157226

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

6

High-throughput

0.479

High

1157229

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.479

High

1157231

ECT2
Protein ECT2

1

3

High-throughput

0.479

High

1157232

ANLN
Anillin

1

2

High-throughput

0.479

High

1157233

DJC11
DnaJ homolog subfamily C member 11

1

8

High-throughput

0.479

High

1157237

BAZ1B
Tyrosine-protein kinase BAZ1B

1

20

High-throughput

0.479

High

1157239

PHF8
Histone lysine demethylase PHF8

1

20

High-throughput

0.479

High

1157241

FAN1
Fanconi-associated nuclease 1

1

1

High-throughput

0.479

High

1157244

TRRAP
Transformation/transcription domain-associated protein

1

9

High-throughput

0.479

High

231566

KIF1B
Kinesin-like protein KIF1B

1

8

High-throughput

0.470

High

281687

WFS1
Wolframin

1

1

High-throughput

0.470

High

527543

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.470

High

660568

GRN
Progranulin

1

1

High-throughput

0.470

High

674182

HMOX2
Heme oxygenase 2

1

2

High-throughput

0.470

High

1034823

LSAMP
Limbic system-associated membrane protein

1

2

High-throughput

0.470

High

1157238

ICAM5
Intercellular adhesion molecule 5

1

8

High-throughput

0.470

High

1157242

SHLB1
Endophilin-B1

1

2

High-throughput

0.470

High

1157227

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1157213

DPF3
Zinc finger protein DPF3

1

20

Small-scale

0.445

High

148945

CTRO
Citron Rho-interacting kinase

1

8

High-throughput

0.437

High

255865

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.437

High

549902

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

9

High-throughput

0.437

High

897756

ABCE1
ATP-binding cassette sub-family E member 1

1

4

High-throughput

0.437

High

1061465

CUL7
Cullin-7

1

6

High-throughput

0.437

High

1138609

OTUD1
OTU domain-containing protein 1

1

2

High-throughput

0.437

High

1157203

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1157206

CUL9
Cullin-9

1

7

High-throughput

0.437

High

1157208

FBXW8
F-box/WD repeat-containing protein 8

1

10

High-throughput

0.437

High

1157217

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.437

High

1157225

TRIM4
E3 ubiquitin-protein ligase TRIM4

1

3

Small-scale

0.437

High

1157209

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

413148

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

1157216

COQA1
Collagen alpha-1(XXVI) chain

1

0

High-throughput

0.268

Low

856399

EFNA4
Ephrin-A4

1

0

High-throughput

0.249

Low

981885

RON
Macrophage-stimulating protein receptor

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024