Protein: PKP3
Plakophilin-3

Gene: PKP3
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q9Y446

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0002159 - desmosome assembly
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1216869

ARMC8
Armadillo repeat-containing protein 8

1

8

Small-scale

0.740

High

970865

DSG1
Desmoglein-1

1

20

Small-scale

0.713

High

1055870

DSC3
Desmocollin-3

1

20

Small-scale

0.713

High

1317644

RHBT2
Rho-related BTB domain-containing protein 2

1

20

High-throughput

0.691

High

800967

MK09
Mitogen-activated protein kinase 9

3

12

High-throughput

0.667

High

1122415

SGO2
Shugoshin 2

3

1

High-throughput

0.667

High

1314972

RBM24
RNA-binding protein 24

3

10

High-throughput

0.667

High

1217207

LACC1
Purine nucleoside phosphorylase LACC1

3

0

High-throughput

0.638

High

1292519

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

3

0

High-throughput

0.638

High

380159

MAS
Proto-oncogene Mas

2

4

High-throughput

0.628

High

792932

GDF5
Growth/differentiation factor 5

2

2

High-throughput

0.628

High

1246300

IL31R
Interleukin-31 receptor subunit alpha

2

7

High-throughput

0.628

High

1300127

CDK15
Cyclin-dependent kinase 15

2

9

High-throughput

0.628

High

1357363

OAZ3
Ornithine decarboxylase antizyme 3

2

2

High-throughput

0.628

High

1377519

FCF1
rRNA-processing protein FCF1 homolog

2

1

High-throughput

0.628

High

1270013

ESR2
Estrogen receptor beta

1

20

High-throughput

0.625

High

542487

PLAK
Junction plakoglobin

1

19

Small-scale

0.621

High

971080

DSC2
Desmocollin-2

1

20

Small-scale

0.621

High

349025

RASN
GTPase NRas

1

20

High-throughput

0.618

High

349752

RASH
GTPase HRas

1

20

High-throughput

0.618

High

350719

RASK
GTPase KRas

1

20

High-throughput

0.618

High

370791

ESR1
Estrogen receptor

1

20

High-throughput

0.618

High

488039

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.618

High

522286

CADH1
Cadherin-1

1

20

High-throughput

0.618

High

545714

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

717461

CTNB1
Catenin beta-1

1

18

High-throughput

0.618

High

818648

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.618

High

852689

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

894615

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

1138345

MYOME
Myomegalin

2

20

High-throughput

0.611

High

1242597

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

2

3

High-throughput

0.611

High

1290274

MITOK
Mitochondrial potassium channel

3

2

High-throughput

0.609

High

1203349

GPBP1
Vasculin

2

0

High-throughput

0.602

High

1343844

ANLN
Anillin

2

8

High-throughput

0.584

High

1261374

CPLX3
Complexin-3

2

1

High-throughput

0.574

High

1377775

KIF3A
Kinesin-like protein KIF3A

2

9

High-throughput

0.574

High

1068523

KPCD1
Serine/threonine-protein kinase D1

2

8

High-throughput

0.571

High

1082659

MK14
Mitogen-activated protein kinase 14

2

13

High-throughput

0.571

High

1355724

CTNA3
Catenin alpha-3

2

20

Small-scale

0.565

High

274701

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

2

1

High-throughput

0.558

High

701702

DSG3
Desmoglein-3

1

20

Small-scale

0.552

High

1048689

DSG2
Desmoglein-2

1

20

Small-scale

0.552

High

165116

SC16A
Protein transport protein Sec16A

1

10

High-throughput

0.536

High

178998

FOXP2
Forkhead box protein P2

1

7

High-throughput

0.536

High

230940

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

10

High-throughput

0.536

High

565993

AATC
Aspartate aminotransferase, cytoplasmic

1

2

High-throughput

0.536

High

686785

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.536

High

794194

MATR3
Matrin-3

1

6

High-throughput

0.536

High

882839

STX17
Syntaxin-17

1

2

High-throughput

0.536

High

961030

CLH1
Clathrin heavy chain 1

1

3

High-throughput

0.536

High

1167367

NPSR1
Neuropeptide S receptor

1

5

High-throughput

0.536

High

1203115

ZC3C1
Zinc finger C3HC-type protein 1

1

2

High-throughput

0.536

High

1233823

CCD82
Coiled-coil domain-containing protein 82

1

1

High-throughput

0.536

High

1239247

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.536

High

1268704

FAN
Protein FAN

1

11

High-throughput

0.536

High

1282603

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

3

High-throughput

0.536

High

1315555

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

15

High-throughput

0.536

High

1315626

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.536

High

1344313

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

1348766

GTSE1
G2 and S phase-expressed protein 1

1

2

High-throughput

0.536

High

1377318

SSUH2
Protein SSUH2 homolog

1

2

High-throughput

0.536

High

1377776

RBM8A
RNA-binding protein 8A

1

6

High-throughput

0.536

High

684419

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

535611

GFAP
Glial fibrillary acidic protein

1

10

High-throughput

0.515

High

1039966

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1186195

DYM
Dymeclin

1

0

High-throughput

0.513

High

1237230

CCYL1
Cyclin-Y-like protein 1

1

0

High-throughput

0.513

High

1333673

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

1349074

AHSP
Alpha-hemoglobin-stabilizing protein

1

0

High-throughput

0.513

High

303737

OR2A4
Olfactory receptor 2A4

1

2

High-throughput

0.489

High

821640

PTSS1
Phosphatidylserine synthase 1

1

2

High-throughput

0.489

High

958797

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

4

High-throughput

0.489

High

1104033

CR021
UPF0711 protein C18orf21

1

1

High-throughput

0.489

High

1281767

PIGT
GPI transamidase component PIG-T

1

1

High-throughput

0.489

High

1356353

FBXL4
F-box/LRR-repeat protein 4

1

1

High-throughput

0.489

High

408966

K1C18
Keratin, type I cytoskeletal 18

1

18

Small-scale

0.481

High

551876

DESP
Desmoplakin

1

15

Small-scale

0.481

High

996022

DSC1
Desmocollin-1

1

20

Small-scale

0.481

High

151265

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

High-throughput

0.479

High

163513

XPO1
Exportin-1

1

10

High-throughput

0.479

High

236540

CIDEA
Lipid transferase CIDEA

1

2

High-throughput

0.479

High

268348

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

278192

PIAS1
E3 SUMO-protein ligase PIAS1

1

4

High-throughput

0.479

High

309185

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

339185

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.479

High

360573

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

13

High-throughput

0.479

High

554135

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

591166

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

652694

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

669096

PML
Protein PML

1

19

High-throughput

0.479

High

721863

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

738144

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

5

High-throughput

0.479

High

843977

FXR1
RNA-binding protein FXR1

1

13

Small-scale

0.479

High

903637

WDR5
WD repeat-containing protein 5

1

13

High-throughput

0.479

High

918191

H4
Histone H4

1

1

High-throughput

0.479

High

1035644

SMAD4
Mothers against decapentaplegic homolog 4

1

7

High-throughput

0.479

High

1052813

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

18

High-throughput

0.479

High

1064288

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1064888

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

1066931

KIF14
Kinesin-like protein KIF14

1

18

High-throughput

0.479

High

1076317

TRIP4
Activating signal cointegrator 1

1

1

High-throughput

0.479

High

1077183

MARE1
Microtubule-associated protein RP/EB family member 1

1

10

Small-scale

0.479

High

1154093

NIPBL
Nipped-B-like protein

1

12

High-throughput

0.479

High

1174019

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

12

Small-scale

0.479

High

1200381

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

7

High-throughput

0.479

High

1239184

ZBT38
Zinc finger and BTB domain-containing protein 38

1

6

Small-scale

0.479

High

1270540

HDAC2
Histone deacetylase 2

1

17

High-throughput

0.479

High

1274371

MED12
Mediator of RNA polymerase II transcription subunit 12

1

12

High-throughput

0.479

High

1281508

FBXW7
F-box/WD repeat-containing protein 7

1

20

High-throughput

0.479

High

1285233

SH3K1
SH3 domain-containing kinase-binding protein 1

1

4

High-throughput

0.479

High

1302360

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

Small-scale

0.479

High

1328322

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

1330576

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

1333833

ECT2
Protein ECT2

1

15

High-throughput

0.479

High

1348349

MTMR4
Myotubularin-related protein 4

1

4

High-throughput

0.479

High

1354176

HDAC6
Histone deacetylase 6

1

20

High-throughput

0.479

High

1354978

ZRAN1
Ubiquitin thioesterase ZRANB1

1

20

High-throughput

0.479

High

1349583

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

1

High-throughput

0.470

High

182967

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

295697

RMP
Unconventional prefoldin RPB5 interactor 1

1

0

Small-scale

0.458

High

1085381

FSCN1
Fascin

1

0

High-throughput

0.458

High

1191097

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.458

High

1244769

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1377777

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

529955

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.445

High

709126

MCM7
DNA replication licensing factor MCM7

1

16

Small-scale

0.445

High

149461

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.437

High

352329

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

1290108

RNF31
E3 ubiquitin-protein ligase RNF31

1

20

High-throughput

0.437

High

1308842

ZFY21
Zinc finger FYVE domain-containing protein 21

1

5

Small-scale

0.437

High

1326227

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

8

High-throughput

0.437

High

1326386

DDX24
ATP-dependent RNA helicase DDX24

1

7

High-throughput

0.437

High

1297427

CI072
Guanine nucleotide exchange factor C9orf72

1

0

Small-scale

0.426

High

1205760

DOPP1
Dolichyldiphosphatase 1

2

0

High-throughput

0.318

High

1231956

ELMD1
ELMO domain-containing protein 1

2

0

High-throughput

0.318

High

1238844

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

0

High-throughput

0.316

High

1012581

CF210
Cilia- and flagella- associated protein 210

1

0

High-throughput

0.279

Low

1089423

SYT16
Synaptotagmin-16

1

0

High-throughput

0.279

Low

1169482

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024