Protein: ETS2
Protein C-ets-2

Gene: ETS2
Organism: Homo sapiens
Interactions: 57
UniProt ID: P15036

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

507357

ERG
Transcriptional regulator ERG

2

18

Small-scale

0.783

High

542752

COP1
E3 ubiquitin-protein ligase COP1

3

17

Small-scale

0.684

High

542742

CDK10
Cyclin-dependent kinase 10

3

1

Small-scale

0.672

High

386026

P53
Cellular tumor antigen p53

3

5

Small-scale

0.670

High

542756

CBP
CREB-binding protein

3

20

Small-scale

0.667

High

542748

ANKS6
Ankyrin repeat and SAM domain-containing protein 6

1

0

High-throughput

0.656

High

542743

ZMY11
Zinc finger MYND domain-containing protein 11

2

20

Small-scale

0.651

High

541970

ETS1
Protein C-ets-1

1

18

Small-scale

0.647

High

542731

SPI1
Transcription factor PU.1

1

17

Small-scale

0.647

High

542738

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

10

Small-scale

0.646

High

542741

EP300
Histone acetyltransferase p300

3

20

Small-scale

0.635

High

542746

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.582

High

542740

PO5F1
POU domain, class 5, transcription factor 1

1

11

Small-scale

0.561

High

542757

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

Small-scale

0.561

High

421254

GDN
Glia-derived nexin

1

5

High-throughput

0.541

High

542735

TTC3
E3 ubiquitin-protein ligase TTC3

1

3

High-throughput

0.541

High

542736

RL15
Large ribosomal subunit protein eL15

1

1

High-throughput

0.541

High

542751

ZBT44
Zinc finger and BTB domain-containing protein 44

1

6

High-throughput

0.541

High

542758

EGLN2
Prolyl hydroxylase EGLN2

1

1

High-throughput

0.541

High

542762

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.541

High

542765

TF3C4
General transcription factor 3C polypeptide 4

1

1

High-throughput

0.541

High

542766

PPME1
Protein phosphatase methylesterase 1

1

1

High-throughput

0.541

High

542767

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.536

High

542744

TWST1
Twist-related protein 1

1

15

Small-scale

0.534

High

542754

TWST2
Twist-related protein 2

1

13

Small-scale

0.534

High

401352

JUN
Transcription factor Jun

1

20

Small-scale

0.527

High

154431

GBRD
Gamma-aminobutyric acid receptor subunit delta

1

0

High-throughput

0.518

High

210536

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.518

High

500708

CLUS
Clusterin

1

0

High-throughput

0.518

High

542747

FOCAD
Focadhesin

1

0

High-throughput

0.518

High

542755

NDRG1
Protein NDRG1

1

0

High-throughput

0.518

High

542729

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

High-throughput

0.515

High

542733

TGFR2
TGF-beta receptor type-2

1

2

High-throughput

0.515

High

542763

IMPCT
Protein IMPACT

1

0

High-throughput

0.513

High

542764

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.513

High

542768

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.513

High

345303

FOS
Protein c-Fos

1

16

Small-scale

0.501

High

475302

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

542760

SRA1
Steroid receptor RNA activator 1

1

1

Small-scale

0.501

High

542753

DMXL2
DmX-like protein 2

1

14

High-throughput

0.494

High

313497

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

0

High-throughput

0.486

High

150843

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

2

High-throughput

0.479

High

162381

XPO1
Exportin-1

1

5

Small-scale

0.479

High

175817

P73
Tumor protein p73

1

5

Small-scale

0.479

High

261393

NCOR1
Nuclear receptor corepressor 1

1

19

Small-scale

0.479

High

377066

GCR
Glucocorticoid receptor

1

13

Small-scale

0.479

High

542730

CEBPB
CCAAT/enhancer-binding protein beta

1

11

High-throughput

0.479

High

542732

EGR1
Early growth response protein 1

1

8

High-throughput

0.479

High

542739

EWS
RNA-binding protein EWS

1

7

High-throughput

0.479

High

542745

NCOA1
Nuclear receptor coactivator 1

1

19

Small-scale

0.479

High

542750

DET1
DET1 homolog

1

3

Small-scale

0.479

High

542759

GFI1
Zinc finger protein Gfi-1

1

2

Small-scale

0.479

High

542761

TLR9
Toll-like receptor 9

1

3

Small-scale

0.479

High

542769

NCOA3
Nuclear receptor coactivator 3

1

20

Small-scale

0.479

High

542734

SERPH
Serpin H1

1

9

High-throughput

0.470

High

542737

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.282

High

542749

RM14
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024