Protein: FBXL6
F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A)

Gene: FBXL6
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q8N531

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

928987

SKP1
S-phase kinase-associated protein 1

4

20

Small-scale

0.905

High

1041091

CUL1
Cullin-1

3

20

Small-scale

0.827

High

432056

HS90A
Heat shock protein HSP 90-alpha

3

12

Small-scale

0.640

High

369995

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

387097

P53
Cellular tumor antigen p53

1

2

Small-scale

0.561

High

311730

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

2

High-throughput

0.536

High

829032

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

3

High-throughput

0.536

High

1184906

CSN6
COP9 signalosome complex subunit 6

1

3

High-throughput

0.536

High

1234106

KKCC1
Calcium/calmodulin-dependent protein kinase kinase 1

1

1

High-throughput

0.536

High

1234111

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

13

High-throughput

0.536

High

1234112

MPP8
M-phase phosphoprotein 8

1

1

High-throughput

0.536

High

1234116

SENP3
Sentrin-specific protease 3

1

1

High-throughput

0.536

High

364975

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

471622

TFPT
TCF3 fusion partner

1

0

High-throughput

0.513

High

1234107

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.513

High

1234109

TFG
Protein TFG

1

0

High-throughput

0.513

High

781639

ETV6
Transcription factor ETV6

1

4

Small-scale

0.512

High

341448

FA12
Coagulation factor XII

1

1

High-throughput

0.489

High

962209

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.489

High

1234108

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

20

High-throughput

0.489

High

1234110

HES6
Transcription cofactor HES-6

1

3

High-throughput

0.489

High

1234113

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.489

High

1234120

NGN3
Neurogenin-3

1

2

High-throughput

0.489

High

374530

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.479

High

499926

CH60
60 kDa heat shock protein, mitochondrial

1

2

Small-scale

0.479

High

515474

CDK4
Cyclin-dependent kinase 4

1

8

Small-scale

0.479

High

590204

CCNA2
Cyclin-A2

1

4

Small-scale

0.479

High

631506

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.479

High

826007

FAS
Fatty acid synthase

1

2

Small-scale

0.479

High

994248

DHX9
ATP-dependent RNA helicase A

1

1

Small-scale

0.479

High

1234115

MBB1A
Myb-binding protein 1A

1

0

Small-scale

0.458

High

800037

VDAC2
Voltage-dependent anion-selective channel protein 2

1

4

Small-scale

0.437

High

821678

K2C6C
Keratin, type II cytoskeletal 6C

1

1

Small-scale

0.437

High

224993

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

923881

CCG7
Voltage-dependent calcium channel gamma-7 subunit

1

0

High-throughput

0.279

Low

1232933

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1234114

RBM4B
RNA-binding protein 4B

1

0

High-throughput

0.279

Low

1234117

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.279

Low

151841

IRS4
Insulin receptor substrate 4

1

0

Small-scale

0.249

Low

455653

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.249

Low

830140

PRI1
DNA primase small subunit

1

0

Small-scale

0.249

Low

917590

H4
Histone H4

1

0

High-throughput

0.249

Low

1234118

RAB9B
Ras-related protein Rab-9B

1

0

Small-scale

0.249

Low

1234119

PNO1
RNA-binding protein PNO1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024