Protein: M3K12
Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)

Gene: M3K12, MAP3K12
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q12852

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004706 - JUN kinase kinase kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

338346

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.825

High

153118

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

17

Small-scale

0.724

High

1018208

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

20

Small-scale

0.724

High

1018215

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

1

20

Small-scale

0.724

High

1018211

MK06
Mitogen-activated protein kinase 6

1

15

High-throughput

0.656

High

800978

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

19

Small-scale

0.647

High

646845

1433T
14-3-3 protein theta

1

20

High-throughput

0.618

High

972497

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

16

Small-scale

0.618

High

1018209

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

16

Small-scale

0.618

High

364875

FRIL
Ferritin light chain

1

2

High-throughput

0.541

High

993394

RGS1
Regulator of G-protein signaling 1

1

3

High-throughput

0.541

High

1018210

T22D1
TSC22 domain family protein 1

1

17

High-throughput

0.541

High

1018213

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

Small-scale

0.529

High

431787

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

438113

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

1018214

FKBPL
FK506-binding protein-like

1

14

Small-scale

0.479

High

971427

RL18A
Large ribosomal subunit protein eL20

1

1

High-throughput

0.457

High

1018212

F10C1
Protein FRA10AC1

1

0

High-throughput

0.288

High


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Last updated: 15 Jul 2024