Protein: SH3R3
E3 ubiquitin-protein ligase SH3RF3 (EC 2.3.2.27) (Plenty of SH3s 2) (SH3 domain-containing RING finger protein 3) (SH3 multiple domains protein 4)

Gene: SH3R3, SH3RF3
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q8TEJ3

Gene Ontology (top 5):
GO:0016567 - protein ubiquitination
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0046330 - positive regulation of JNK cascade
GO:0046872 - metal ion binding
GO:0051865 - protein autoubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

228156

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.618

High

476095

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

12

Small-scale

0.618

High

1217966

KSR1
Kinase suppressor of Ras 1

1

10

High-throughput

0.618

High

1256275

TESK2
Dual specificity testis-specific protein kinase 2

1

2

High-throughput

0.618

High

1256289

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

1

14

Small-scale

0.618

High

683567

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.604

High

904904

1433G
14-3-3 protein gamma

3

20

High-throughput

0.604

High

1034763

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

Small-scale

0.561

High

253384

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

20

High-throughput

0.553

High

1032931

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

20

Small-scale

0.553

High

1136530

SPD2A
SH3 and PX domain-containing protein 2A

1

19

High-throughput

0.553

High

1203939

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

13

High-throughput

0.553

High

1256274

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

17

High-throughput

0.553

High

1256278

RTKN
Rhotekin

1

3

High-throughput

0.553

High

1256280

TANC2
Protein TANC2

1

9

High-throughput

0.553

High

925460

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.538

High

1026931

PAK2
Serine/threonine-protein kinase PAK 2

1

20

Small-scale

0.528

High

199129

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

13

Small-scale

0.500

High

909849

1433E
14-3-3 protein epsilon

1

12

High-throughput

0.489

High

982315

1433F
14-3-3 protein eta

1

20

High-throughput

0.489

High

153151

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

10

Small-scale

0.479

High

800925

MK09
Mitogen-activated protein kinase 9

1

7

Small-scale

0.479

High

800990

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

20

Small-scale

0.479

High

894241

CDC42
Cell division control protein 42 homolog

1

20

Small-scale

0.479

High

1042121

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1243861

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1256285

LIMA1
LIM domain and actin-binding protein 1

1

19

High-throughput

0.479

High

1256286

ZBT21
Zinc finger and BTB domain-containing protein 21

1

3

High-throughput

0.479

High

1256288

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

12

Small-scale

0.479

High

538331

ENPL
Endoplasmin

1

4

High-throughput

0.470

High

1256279

B2L13
Bcl-2-like protein 13

1

1

Small-scale

0.439

High

166589

DCLK1
Serine/threonine-protein kinase DCLK1

1

7

High-throughput

0.437

High

196482

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

2

High-throughput

0.437

High

230897

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

12

High-throughput

0.437

High

237276

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.437

High

264366

GGYF1
GRB10-interacting GYF protein 1

1

6

High-throughput

0.437

High

598506

NF1
Neurofibromin

1

11

High-throughput

0.437

High

673611

MPIP3
M-phase inducer phosphatase 3

1

2

High-throughput

0.437

High

800812

MK08
Mitogen-activated protein kinase 8

1

7

Small-scale

0.437

High

880791

HDAC4
Histone deacetylase 4

1

13

High-throughput

0.437

High

1020196

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

9

High-throughput

0.437

High

1139619

DEN4C
DENN domain-containing protein 4C

1

8

High-throughput

0.437

High

1167936

GGYF2
GRB10-interacting GYF protein 2

1

20

High-throughput

0.437

High

1256240

DEN1A
DENN domain-containing protein 1A

1

8

High-throughput

0.437

High

1256276

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

1

High-throughput

0.437

High

1256277

LPIN3
Phosphatidate phosphatase LPIN3

1

1

High-throughput

0.437

High

1256281

KI13B
Kinesin-like protein KIF13B

1

16

High-throughput

0.437

High

1256282

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

20

High-throughput

0.437

High

1256283

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

2

High-throughput

0.437

High

1256284

CING
Cingulin

1

6

High-throughput

0.437

High

1256287

PPM1H
Protein phosphatase 1H

1

4

High-throughput

0.437

High

1256290

CBY1
Protein chibby homolog 1

1

1

High-throughput

0.437

High

1256291

KCTD3
BTB/POZ domain-containing protein KCTD3

1

6

High-throughput

0.437

High


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Last updated: 15 Jul 2024