Protein: OTUD5
OTU domain-containing protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA)

Gene: OTUD5
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q96G74

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0014033 - neural crest cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476196

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

10

12

Small-scale

0.972

High

599712

TNAP3
Tumor necrosis factor alpha-induced protein 3

2

4

High-throughput

0.811

High

1255809

OTU7A
OTU domain-containing protein 7A

1

4

High-throughput

0.691

High

387291

P53
Cellular tumor antigen p53

3

2

Small-scale

0.688

High

1079576

NEDD8
NEDD8

1

4

Small-scale

0.647

High

1291931

RABX5
Rab5 GDP/GTP exchange factor

2

1

High-throughput

0.628

High

1291932

TRI35
E3 ubiquitin-protein ligase TRIM35

2

3

High-throughput

0.628

High

1291922

OTUD5
OTU domain-containing protein 5

1

7

High-throughput

0.618

High

660663

GRN
Progranulin

3

1

High-throughput

0.609

High

1024735

TRAF3
TNF receptor-associated factor 3

2

7

Small-scale

0.601

High

1291929

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

2

0

Small-scale

0.585

High

304294

UBR5
E3 ubiquitin-protein ligase UBR5

1

7

Small-scale

0.561

High

676966

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

Small-scale

0.561

High

996826

SSRP1
FACT complex subunit SSRP1

1

2

Small-scale

0.561

High

1069765

NONO
Non-POU domain-containing octamer-binding protein

1

6

Small-scale

0.561

High

153474

PDCD5
Programmed cell death protein 5

1

0

Small-scale

0.549

High

583546

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.537

High

624994

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.537

High

867244

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

Small-scale

0.537

High

1291933

SP16H
FACT complex subunit SPT16

1

0

Small-scale

0.537

High

323961

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.536

High

598273

FLNA
Filamin-A

1

6

High-throughput

0.515

High

643900

SYVC
Valine--tRNA ligase

1

2

High-throughput

0.515

High

675059

KPYR
Pyruvate kinase PKLR

1

1

High-throughput

0.515

High

850149

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

4

High-throughput

0.515

High

963877

SET
Protein SET

1

1

High-throughput

0.515

High

1291925

CYBP
Calcyclin-binding protein

1

1

High-throughput

0.515

High

1291927

LANC2
LanC-like protein 2

1

1

High-throughput

0.515

High

871733

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

533720

GYS1
Glycogen [starch] synthase, muscle

1

0

High-throughput

0.493

High

739404

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

0

High-throughput

0.493

High

924783

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.493

High

1291926

PYRG2
CTP synthase 2

1

0

High-throughput

0.493

High

160706

AURKA
Aurora kinase A

1

11

Small-scale

0.479

High

681979

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.479

High

890796

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.479

High

1230511

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

Small-scale

0.479

High

1291923

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1092965

LONF2
LON peptidase N-terminal domain and RING finger protein 2

1

2

High-throughput

0.470

High

651944

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

1161820

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1203563

STING
Stimulator of interferon genes protein

1

0

Small-scale

0.458

High

1291928

RN146
E3 ubiquitin-protein ligase RNF146

1

0

Small-scale

0.458

High

1291924

LN28A
Protein lin-28 homolog A

1

4

High-throughput

0.445

High

169120

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.438

High

1291930

DS13B
Dual specificity protein phosphatase 13B

1

2

High-throughput

0.437

High


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Last updated: 15 Jul 2024