Protein: PTPR2
Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.-) (EC 3.1.3.48) (Islet cell autoantigen-related protein) (IAR) (ICAAR) (Phogrin) [Cleaved into: IA-2beta60]

Gene: PTPR2, PTPRN2
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q92932

Gene Ontology (top 5):
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005886 - plasma membrane
GO:0006470 - protein dephosphorylation
GO:0006629 - lipid metabolic process
GO:0007269 - neurotransmitter secretion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1088220

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

2

19

High-throughput

0.811

High

490002

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

18

High-throughput

0.691

High

508134

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.691

High

523096

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

High-throughput

0.691

High

1245651

MSPD2
Motile sperm domain-containing protein 2

2

5

High-throughput

0.628

High

924751

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

377557

GCR
Glucocorticoid receptor

2

6

High-throughput

0.584

High

1273025

TELO2
Telomere length regulation protein TEL2 homolog

2

1

High-throughput

0.558

High

1273015

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

18

Small-scale

0.545

High

154398

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

10

High-throughput

0.536

High

277616

PAK3
Serine/threonine-protein kinase PAK 3

1

6

High-throughput

0.536

High

834324

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

1273019

SORT
Sortilin

1

0

High-throughput

0.513

High

1273020

NFIP1
NEDD4 family-interacting protein 1

1

0

High-throughput

0.513

High

1047789

CKAP5
Cytoskeleton-associated protein 5

1

17

Small-scale

0.508

High

1273022

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

4

Small-scale

0.508

High

195604

SGSM2
Small G protein signaling modulator 2

1

4

High-throughput

0.489

High

901511

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

6

High-throughput

0.489

High

957750

XIAP
E3 ubiquitin-protein ligase XIAP

1

2

High-throughput

0.489

High

1036309

BIRC2
Baculoviral IAP repeat-containing protein 2

1

3

High-throughput

0.489

High

1189549

MON2
Protein MON2 homolog

1

4

High-throughput

0.489

High

502398

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.479

High

588646

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

6

High-throughput

0.479

High

1034612

GOGA4
Golgin subfamily A member 4

1

2

High-throughput

0.479

High

1273021

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1273023

UBQL4
Ubiquilin-4

1

6

High-throughput

0.464

High

1040197

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1220951

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

1

Small-scale

0.457

High

1047195

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

10

High-throughput

0.445

High

160123

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.437

High

207974

XPOT
Exportin-T

1

20

High-throughput

0.437

High

273924

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.437

High

277106

STAM2
Signal transducing adapter molecule 2

1

10

High-throughput

0.437

High

335157

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.437

High

359393

K1C14
Keratin, type I cytoskeletal 14

1

3

High-throughput

0.437

High

445098

K1C16
Keratin, type I cytoskeletal 16

1

3

High-throughput

0.437

High

575522

EGR1
Early growth response protein 1

1

4

High-throughput

0.437

High

610895

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.437

High

789902

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.437

High

980304

K1C17
Keratin, type I cytoskeletal 17

1

3

High-throughput

0.437

High

1140677

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.437

High

1159561

TTC27
Tetratricopeptide repeat protein 27

1

5

High-throughput

0.437

High

1219349

CUL9
Cullin-9

1

2

High-throughput

0.437

High

1232681

FBXW8
F-box/WD repeat-containing protein 8

1

2

High-throughput

0.437

High

1266778

SNX19
Sorting nexin-19

1

1

High-throughput

0.437

High

1268213

GCN1
Stalled ribosome sensor GCN1

1

16

High-throughput

0.437

High

1268355

NU205
Nuclear pore complex protein Nup205

1

1

High-throughput

0.437

High

1270599

STAM1
Signal transducing adapter molecule 1

1

10

High-throughput

0.437

High

1273016

TNPO1
Transportin-1

1

16

High-throughput

0.437

High

1273018

CLCC1
Chloride channel CLIC-like protein 1

1

1

High-throughput

0.437

High

1273024

RMND1
Required for meiotic nuclear division protein 1 homolog

1

1

High-throughput

0.437

High

725845

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

1135519

INT11
Integrator complex subunit 11

1

0

High-throughput

0.279

Low

1273017

TM186
Transmembrane protein 186

1

0

High-throughput

0.279

Low

931547

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.249

Low

1062466

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.249

Low

1131247

NU188
Nucleoporin NUP188

1

0

High-throughput

0.249

Low

1204558

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.249

Low

1217256

HID1
Protein HID1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024