Protein: VEGFA
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]

Gene: VEGFA
Organism: Homo sapiens
Interactions: 52
UniProt ID: P15692

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0001541 - ovarian follicle development
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001570 - vasculogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549560

VGFR2
Vascular endothelial growth factor receptor 2

19

20

Small-scale

0.988

High

155260

NRP1
Neuropilin-1

16

7

Small-scale

0.986

High

549553

VGFR1
Vascular endothelial growth factor receptor 1

12

20

Small-scale

0.980

High

549551

VEGFA
Vascular endothelial growth factor A, long form

7

10

Small-scale

0.963

High

549564

VEGFB
Vascular endothelial growth factor B

3

8

High-throughput

0.861

High

234418

NRP2
Neuropilin-2

2

7

Small-scale

0.778

High

549563

PLGF
Placenta growth factor

2

10

Small-scale

0.737

High

549574

HIF1A
Hypoxia-inducible factor 1-alpha

6

0

Small-scale

0.695

High

549568

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

2

Small-scale

0.647

High

549566

NGAL
Neutrophil gelatinase-associated lipocalin

1

0

High-throughput

0.630

High

451067

SPRC
SPARC

2

3

Small-scale

0.602

High

549567

SMAD3
Mothers against decapentaplegic homolog 3

2

2

Small-scale

0.601

High

549571

SMAD4
Mothers against decapentaplegic homolog 4

2

2

Small-scale

0.601

High

549582

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

3

Small-scale

0.586

High

434809

CXB1
Gap junction beta-1 protein

2

0

High-throughput

0.580

High

549578

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

549581

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.580

High

358968

CRYAB
Alpha-crystallin B chain

2

1

Small-scale

0.563

High

362779

FINC
Fibronectin

1

7

Small-scale

0.561

High

549580

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

2

High-throughput

0.541

High

549556

CCN2
CCN family member 2

1

0

Small-scale

0.537

High

549576

ACTBL
Beta-actin-like protein 2

1

1

High-throughput

0.536

High

528482

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

549579

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.518

High

434923

SP1
Transcription factor Sp1

1

1

Small-scale

0.501

High

549558

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

Small-scale

0.501

High

549570

SP3
Transcription factor Sp3

1

1

Small-scale

0.501

High

549573

IBP7
Insulin-like growth factor-binding protein 7

1

3

Small-scale

0.501

High

549583

LYVE1
Lymphatic vessel endothelial hyaluronic acid receptor 1

1

1

Small-scale

0.501

High

549584

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

0

Small-scale

0.486

High

372988

VTNC
Vitronectin

1

0

Small-scale

0.480

High

403589

AP2A
Transcription factor AP-2-alpha

1

0

Small-scale

0.480

High

168292

ANGP2
Angiopoietin-2

1

1

Small-scale

0.479

High

345307

FOS
Protein c-Fos

1

1

Small-scale

0.479

High

434614

TSP1
Thrombospondin-1

1

7

Small-scale

0.479

High

549554

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

4

Small-scale

0.479

High

549555

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

1

2

Small-scale

0.479

High

549562

STAT3
Signal transducer and activator of transcription 3

1

1

Small-scale

0.479

High

549572

SMAD2
Mothers against decapentaplegic homolog 2

1

2

Small-scale

0.479

High

159874

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

Small-scale

0.458

High

414153

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.458

High

431501

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

500711

CLUS
Clusterin

1

0

Small-scale

0.458

High

549552

ITF2
Transcription factor 4

1

0

Small-scale

0.458

High

549557

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

549559

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

549565

GSK3B
Glycogen synthase kinase-3 beta

1

0

Small-scale

0.458

High

549577

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

0

Small-scale

0.458

High

549575

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

549569

U2AF1
Splicing factor U2AF 35 kDa subunit

1

0

High-throughput

0.282

High

549561

MOT8
Monocarboxylate transporter 8

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024